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Systematic review methodology

Sarah Barrett, Gerard G Hanna, Laure Marignol
Standard of care radiotherapy in LA-NSCLC is 60-66 Gy in 30-33 fractions. However outcomes for these patients are poor with 5-year survival in the range of 10-20%. Randomised controlled trials have shown that dose escalation in a linear fashion does not improve outcomes for all patients, thus there is a need to tailor the prescription to the individual patient. This review assesses the strategies published to personalise the radiation therapy dose prescription in LA-NSCLC. A systematic and scoping search of the literature was performed to identify studies that met the inclusion criteria...
June 13, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Ying-Ying Liang, Fan Xu, Yuan Guo, Jin Wang
OBJECTIVE: To assess the added benefit of combining different MRI techniques for preoperative diagnosis of parotid tumors when compared to conventional MRI and advanced MRI techniques alone with meta-analysis. METHODS: A comprehensive PubMed electronic database search was performed for original diagnostic studies up to July 2017. The methodologic quality of each study was evaluated by two independent reviewers who used the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool...
June 7, 2018: Clinical Imaging
Marianne de Vasconcelos Carvalho, Sandra Lúcia Dantas de Moraes, Cleidiel Aparecido Araujo Lemos, Joel Ferreira Santiago Júnior, Belmiro Cavalcanti do Egito Vasconcelos, Eduardo Piza Pellizzer
OBJECTIVE: The aim of this systematic review was to compare outcomes between surgical and non-surgical treatment of actinic cheilitis (AC). MATERIALS AND METHODS: A systematic review and meta-analysis based on the Preferred Reporting Items for Systematic reviews and Meta-Analyses guideline was performed. A search of PubMed/MEDLINE, Web of Science, and Cochrane Library databases was conducted. Articles were selected based on the inclusion criteria: randomized clinical trials, prospective/retrospective studies, and case series with at least 10 patients, with a minimum follow-up period of 6 months...
June 16, 2018: Oral Diseases
Timothy David Robbins, Sarah N Lim Choi Keung, Theodoros N Arvanitis
Enabling successful active ageing is an international priority to meet the challenges of increasing life expectancy. Digital strategies, such as telemedicine and e-health, offer the potential to deliver active ageing in a cost-effective manner at scale. This article aims to establish the extent to which the research literature considers e-health-based and telemedicine-based active ageing interventions. A systematic review was conducted according to PRISMA standards. Independently, two authors searched the Cochrane, EMBASE & CINAHL databases, with subsequent independent extraction and semi-quantitative analysis...
August 2018: Maturitas
Yuhao Wu, Zhichao Wu, Junmeng Zheng, Yonggang Li, Yuehang Zhou, Hongyu Kuang, Xin Jin, Chun Wu
BACKGROUD: A meta-analysis was performed to compare the differences in outcomes between sutureless technique and conventional surgery for primary repair of Total Anomalous Pulmonary Venous Connection(TAPVC). METHODS: Electronic databases, including PubMed, EMbase, Medline, CNKI, Wanfang Data and Weipu Data were searched systematically for the literature aimed mainly at comparing the therapeutic effects for primary repair of TAPVC administered by sutureless technique and conventional surgery...
June 15, 2018: Journal of Cardiothoracic Surgery
M E Kelly, F Patterson, S O'Flynn, J Mulligan, A W Murphy
BACKGROUND: The purpose of this paper is to systematically review the literature with respect to stakeholder views of selection methods for medical school admissions. METHODS: An electronic search of nine databases was conducted between January 2000-July 2014. Two reviewers independently assessed all titles (n = 1017) and retained abstracts (n = 233) for relevance. Methodological quality of quantitative papers was assessed using the MERSQI instrument. The overall quality of evidence in this field was low...
June 15, 2018: BMC Medical Education
Christos I Athanasiou, Angeliki Kopsini
INTRODUCTION: In the field of antimicrobial resistance, the number of studies that use time series data has increased recently. The purpose of this study is the systematic review of all studies on antibacterial consumption and on Pseudomonas aeruginosa resistance in healthcare settings, that have used time series data. METHODS: A systematic review of the literature till June 2017 was conducted. All the studies that have used time series data and have examined the inhospital antibiotic consumption and Ps...
June 12, 2018: Journal of Global Antimicrobial Resistance
Michael F Knox, Lucy S Chipchase, Siobhan M Schabrun, Rick J Romero, Paul W M Marshall
BACKGROUND CONTEXT: Despite altered anticipatory (APAs) and compensatory postural adjustments (CPAs) being hypothesized to contribute to the onset and persistence of low back pain (LBP), results from studies comparing people with and without LBP are conflicting. PURPOSE: This systematic review aimed to determine whether anticipatory (APAs) or compensatory postural adjustments (CPAs) are altered in the presence of acute and chronic low back pain (LBP). STUDY DESIGN: A systematic review of studies was carried out...
June 12, 2018: Spine Journal: Official Journal of the North American Spine Society
Troy Morrison, Sara Jones, Ryan S Causby, Kerry Thoirs
INTRODUCTION: Diabetes mellitus (DM) is associated with hyperglycaemia and advanced glycosylation end-products. In the foot, the consequences of chronic or uncontrolled diabetes are micro and macrovascular disease, neuropathy, reduced joint mobility and structural and soft tissue changes that increase the risk of ulcer development and amputation. Diabetes foot assessment currently includes a comprehensive history, neurological and vascular assessments and examination focussed on dermatological and musculoskeletal abnormalities...
2018: PloS One
James R Bailey, Christopher Kim, Eduard Alentorn-Geli, Donald T Kirkendall, Leila Ledbetter, Dean C Taylor, Alison P Toth, Grant E Garrigues
BACKGROUND: Surgical management of rotator cuff tears is controversial and complex, ranging from nonoperative management to reverse shoulder arthroplasty. PURPOSE: To systematically review and evaluate the outcomes of graft augmentation or interposition versus rotator cuff repair (RCR) alone and evaluate via meta-analysis whether the use of a graft leads to superior outcomes versus RCR alone. STUDY DESIGN: Systematic review and meta-analysis...
June 1, 2018: American Journal of Sports Medicine
R El Arab, M Sagbakken
Background: This review aims to explore the healthcare needs and access to healthcare services among Syrian refugees in Jordan. Furthermore, it identifies possible ways of responding to such needs within the framework of the structural challenges faced in this particular context. Methods: Through qualitative techniques, this study systematically reviewed nine articles identified in academic and international organizations' databases. Six articles are from scholarly sources, while three are published reports or commentary articles; thus, there are variations in methodological rigour...
June 13, 2018: European Journal of Public Health
Xingke Cai, Yuting Luo, Bilu Liu, Hui-Ming Cheng
Extensive research on two-dimensional (2D) materials has triggered the renaissance of an old topic, that is, the intercalation and exfoliation of layer materials. Such top-down exfoliation produced 2D materials and their dispersions have several advantages including low cost, scalable production capability, solution processability, and versatile functionalities stemming from the large number of species of layer materials, and show promising potential in many applications. In recent years, many new methods have been developed for exfoliating layer materials to 2D materials for different application purposes...
June 15, 2018: Chemical Society Reviews
L J Broome, C Izura, N Lorenzo-Dus
Data presented within this article supports the findings of the manuscript "A systematic review of fantasy driven vs contact driven internet-initiated sexual offences: Discrete or overlapping typologies?" (Broome et al., in press) [1]. Inclusion and Exclusion criteria of study selection, PICO Formulation of Study Appraisal, as well as the Study Characteristics and Methodology of included studies are presented.
June 2018: Data in Brief
Andika Afriansyah, Agus Rizal Ardy Hariandy Hamid, Chaidir Arif Mochtar, Rainy Umbas
Aim: Metastatic prostate cancer (mPCa) has a poor outcome with median survival of two to five years. The use of androgen deprivation therapy (ADT) is a gold standard in management of this stage.  Aim of this study is to analyze the prognostic value of PSA kinetics of patient treated with hormonal therapy related to survival from several published studies Method: Systematic review and meta-analysis was performed using literature searching in the electronic databases of MEDLINE, Science Direct, and Cochrane Library...
2018: F1000Research
Lianping Ti, Michelle Ng, Lindila Awendila, Patrizia Maria Carrieri
INTRODUCTION: People living with hepatitis C virus (HCV) infection are disproportionately over-represented in the healthcare system due to various individual and contextual circumstances, including comorbidities and socioeconomic marginalisation. With growing trends in morbidity and mortality related to HCV infection, HCV is becoming a significant health and financial burden on the healthcare system, particularly in acute hospital settings. It is noteworthy that with the advent of direct-acting antiviral therapy the increasing number of patients who are cured of HCV could potentially result in different patterns of hospital-related outcomes over time...
June 14, 2018: BMJ Open
Scott Weich, Sarah-Jane Hannah Fenton, Kamaldeep Bhui, Sophie Staniszewska, Jason Madan, Michael Larkin, Elizabeth Newton, David Crepaz-Keay, Alastair Canaway, Charlotte Croft, Frances Griffiths
INTRODUCTION: Inpatient mental healthcare continues to be an area of high risk and where patients report negative experiences. To ensure the patient voice is heard, National Health Service (NHS) Trusts are required to collect feedback from patients routinely. We do not know what kinds of feedback are most important or what management processes are needed to translate this into effective action plans. Further, we do not know if this makes any difference to the patients themselves. This study seeks to explore which of the many different approaches to collecting and using patient experience data are the most useful for supporting improvements in inpatient mental healthcare...
June 14, 2018: BMJ Open
Shuaijun Guo, Rebecca Armstrong, Elizabeth Waters, Thirunavukkarasu Sathish, Sheikh M Alif, Geoffrey R Browne, Xiaoming Yu
OBJECTIVE: Improving health literacy at an early age is crucial to personal health and development. Although health literacy in children and adolescents has gained momentum in the past decade, it remains an under-researched area, particularly health literacy measurement. This study aimed to examine the quality of health literacy instruments used in children and adolescents and to identify the best instrument for field use. DESIGN: Systematic review. SETTING: A wide range of settings including schools, clinics and communities...
June 14, 2018: BMJ Open
Thomas Waterfield, Derek Fairley, Fiona Lynn, Bronagh Blackwood, Michael D Shields
BACKGROUND: Meningococcal disease (MD) is notoriously difficult to diagnose in the early stages of the illness and presents similarly to many self-limiting viral infections. This mandates a cautious approach to diagnosis and initial management of suspected MD with many children receiving precautionary broad-spectrum intravenous antibiotics. Despite this approach, some children are still diagnosed late. In the last 10 years, there have been advances in nucleic acid amplification techniques, and there is now a rapid test that can detect meningococcal DNA in under 30 min...
June 15, 2018: Systematic Reviews
Michelle Cleary, Denis Visentin, Sancia West, Violeta Lopez, Rachel Kornhaber
OBJECTIVE: To synthesize the evidence that explored resilience and emotional intelligence in undergraduate nursing students. BACKGROUND: Nursing is a demanding profession that offers unique challenges. Emotional intelligence and resilience are traits that can allow nursing students to effectively respond to challenges in professional placements and future practice. DESIGN: An integrative review incorporating both quantitative and qualitative research designs...
May 30, 2018: Nurse Education Today
Sarkis Manoukian, Sally Stewart, Stephanie Dancer, Nicholas Graves, Helen Mason, Agi McFarland, Chris Robertson, Jacqui Reilly
BACKGROUND: Healthcare-associated infection (HAI) affects millions of patients worldwide. HAI is associated with increased healthcare costs, owing primarily to increased hospital length of stay (LOS) but calculating these costs is complicated due to time-dependent bias. Accurate estimation of excess LOS due to HAI is essential to ensure we invest in cost-effective infection prevention and control (IPC) measures. AIM: To identify and review the main statistical methods that have been employed to estimate differential LOS between patients with, and without, HAI; to highlight and discuss potential biases of all statistical approaches...
June 11, 2018: Journal of Hospital Infection
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