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https://www.readbyqxmd.com/read/28431477/duration-of-orthognathic-surgical-treatment
#1
Jaakko Paunonen, Mika Helminen, Timo Peltomäki
OBJECTIVE: The objective of this study was to determine the duration of orthognathic-surgical treatment conducted with conventional pre- and post-surgical orthodontic treatment phases. MATERIAL AND METHODS: The study material was comprised of the files of 185 consecutive patients treated in Oral and Maxillofacial Unit, Tampere University Hospital, Finland, in 2007-2014. The files were reviewed and the following data was obtained: gender and age of patients, ICD-10 diagnosis, type of malocclusion, duration of pre- and post-surgical orthodontic treatment and type of operation...
April 21, 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28430723/colpocleisis-a-survey-of-current-practice-patterns
#2
Keisha Jones, Gary Wang, Robert Romano, Peter St Marie, Oz Harmanli
BACKGROUND: Currently, there are no standard treatment guidelines for colpocleisis. Clinical practice varies widely for this safe and effective procedure. OBJECTIVE: The aim of this study was to evaluate the current practice patterns in the United States among surgeons who perform colpocleisis. METHODS: A 27-item anonymous Web-based survey was sent to all practicing physicians affiliated with the American Urogynecologic Society. It consisted of questions regarding the demographic background of the physicians and their current practice as it relates to colpocleisis...
April 20, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28429449/non-pincer-type-manganese-complexes-as-efficient-catalysts-for-the-hydrogenation-of-esters
#3
Robbert van Putten, Evgeny A Uslamin, Marcel Garbe, Chong Liu, Angela Gonzalez-de-Castro, Martin Lutz, Kathrin Junge, Emiel J M Hensen, Matthias Beller, Laurent Lefort, Evgeny A Pidko
Catalytic hydrogenation of carboxylic acid esters is essential for the green production of pharmaceuticals, fragrances, and fine chemicals. Herein, we report the efficient hydrogenation of esters with manganese catalysts based on simple bidentate aminophosphine ligands. Monoligated Mn PN complexes are particularly active for the conversion of esters into the corresponding alcohols at Mn concentrations as low as 0.2 mol % in the presence of sub-stoichiometric amounts of KO(t) Bu base.
April 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28411670/3-10-mise-en-s%C3%A3-curit%C3%A3-et-alerte-des-secours
#4
Xavier Huber, Clément Derkenne, Frédéric Lemoine, Hugues Lefort, Jean-Pierre Tourtier
No abstract text is available yet for this article.
April 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28410392/cyfip1-is-directly-controlled-by-notch1-and-down-regulated-in-cutaneous-squamous-cell-carcinoma
#5
Piotr J Dziunycz, Johannes Neu, Karine Lefort, Nadia Djerbi, Sandra N Freiberger, Guergana Iotzova-Weiss, Lars E French, Gian-Paolo Dotto, Günther F Hofbauer
Squamous cell carcinoma of the skin (SCC) represents one of the most common cancers in the general population and is associated with a substantial risk of metastasis. Previous work uncovered the functional role of CYFIP1 in epithelial tumors as an invasion inhibitor. It was down-regulated in some cancers and correlated with the metastatic properties of these malignant cells. We investigated its role and expression mechanisms in SCC. We analyzed the expression of CYFIP1 in patient derived SCC, primary keratinocytes and SCC cell lines, and correlated it to the differentiation and NOTCH1 levels...
2017: PloS One
https://www.readbyqxmd.com/read/28392417/pharmacological-inhibition-of-carnitine-palmitoyltransferase-1-restores-mitochondrial-oxidative-phosphorylation-in-human-trifunctional-protein-deficient-fibroblasts
#6
Bruno Lefort, Elodie Gouache, Cécile Acquaviva, Marine Tardieu, Jean François Benoist, Jean-François Dumas, Stéphane Servais, Stéphan Chevalier, Christine Vianey-Saban, François Labartheh
BACKGROUND: Mitochondrial Trifunctional Protein deficiency (TFPD) is a severe genetic disease characterized by altered energy metabolism and accumulation of long-chain (LC) acylcarnitines in blood and tissues. This accumulation could impair the mitochondrial oxidative phosphorylation (OxPhos), contributing to the non-optimal outcome despite conventional diet therapy with medium-chain triglycerides (MCT). METHOD: Acylcarnitine and OxPhos parameters were measured in TFPD-fibroblasts obtained from 8 children and cultured in medium mimicking fasting (LCFA) or conventional treatment (MCT), with or without Etomoxir (ETX) an inhibitor of carnitine palmitoyltransferase 1 (CPT1) activity, and were compared to results obtained with fibroblasts from 5 healthy-control children...
April 6, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28382677/selective-hydrogenation-of-%C3%AE-%C3%AE-unsaturated-aldehydes-and-ketones-by-air-stable-ruthenium-nns-complexes
#7
Johannes Gerardus de Vries, Pim Puylaert, Richard van Heck, Yuting Fan, Anke Spannenberg, Wolfgang Baumann, Matthias Beller, Jonathan Medlock, Werner Bonrath, Lauren Lefort, Sandra Hinze
The selective hydrogenation of the carbonyl functionality of α,β-unsaturated aldehydes and ketones is catalysed by ruthenium dichloride complexes bearing a tridentate NNS ligand as well as triphenylphosphine. The tridentate ligand backbone is flexible, as evidenced by the equilibrium observed in solution between the cis- and trans-isomers of the dichloride precatalysts, as well as crystal structures of several of these complexes. The complexes are activated by base in the presence of hydrogen and readily hydrogenate carbonyl functionalities under mild conditions...
April 5, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28366250/-emergency-plans-in-crisis-situations
#8
Laure Alhanati, Hugues Lefort, Noémie Galinou, Catherine Rivet, Stéphane Travers, Jean-Pierre Tourtier
In November 2015, in Paris, a wave of terrorist attacks brought horror to France. The medical and nursing teams were severely tested but demonstrated efficiency and courage. The organisation of the emergency response requires fast and essential decision making and actions.
April 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28304415/vaginal-obliterative-procedures-for-pelvic-organ-prolapse-a-systematic-review
#9
REVIEW
Gunhilde M Buchsbaum, Toy Gee Lee
Importance: Pelvic organ prolapse is a common condition, the prevalence of which is likely to increase with the aging of our population. Also changing are parameters by which outcomes are assessed, shifting toward patient-centered care. Objective: To review vaginal obliterative procedures for surgical treatment of advanced pelvic organ prolapse historically and to discuss evidence on indications for colpocleisis, outcomes, and complications, as well as review pros and cons for concomitant vaginal hysterectomy and anti-incontinence procedures...
March 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28287415/dietary-buglossoides-arvensis-oil-increases-circulating-n-3-polyunsaturated-fatty-acids-in-a-dose-dependent-manner-and-enhances-lipopolysaccharide-stimulated-whole-blood-interleukin-10-a-randomized-placebo-controlled-trial
#10
Natalie Lefort, Rémi LeBlanc, Marc E Surette
Buglossoides arvensis (Ahiflower) oil is a dietary oil rich in stearidonic acid (20% SDA; 18:4 n-3). The present randomized, double blind, placebo-controlled clinical trial investigated the effects of three Ahiflower oil dosages on omega-3 polyunsaturated fatty acid (PUFA) content of plasma and mononuclear cells (MCs) and of the highest Ahiflower dosage on stimulated cytokine production in blood. Healthy subjects (n = 88) consumed 9.7 mL per day for 28 days of 100% high oleic sunflower oil (HOSO); 30% Ahiflower oil (Ahi) + 70% HOSO; 60% Ahi + 40% HOSO; and 100% Ahi...
March 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28284407/-creation-of-a-medical-work-station-for-use-in-community-based-care
#11
REVIEW
Samuel Mercier, Fabrice Desauty, Christophe Lamache, Hugues Lefort
In community-based care, the teams must adapt to the environment and perform a number of technical procedures. Foldable medical equipment has been developed and patented, enabling the care provision to approach hospital standards and improving working conditions in this context.
March 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28274523/intraoperative-stenting-of-pulmonary-artery-stenosis-in-children-with-congenital-heart-disease
#12
Mathilde Meot, Bruno Lefort, Jean Marc El Arid, Nathalie Soulé, Julie Lothion-Boulanger, François Lengellé, Alain Chantepie, Paul Neville
BACKGROUND: Branch pulmonary artery (BPA) stenosis is frequently associated with congenital heart disease. Management of BPA stenosis is challenging for surgeons due to a high rate of recurrence. The purpose of this study was to assess the results of intraoperative pulmonary artery stenting associated with or without surgical angioplasty. METHODS: We included 33 children from our center between January 2008 and July 2014. Patients had pulmonary atresia with ventricular septal defect (13), tetralogy of Fallot (10), troncus arteriosus (4), double outlet right ventricle (2), and single left or right ventricle (4)...
March 5, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28274035/stability-of-vertical-horizontal-and-angular-parameters-following-superior-repositioning-of-maxilla-by-le-fort-i-osteotomy-a-cephalometric-study
#13
Pruthvi Raj Hanthur Venkategowda, A T Prakash, E T Roy, K Sadashiva Shetty, Surbhi Thakkar, Rajkumar Maurya
INTRODUCTION: The restoration of normal jaw function, optimal facial aesthetics and long term stability are the goals of any orthognathic surgical procedures. During the last two decades, several cephalometric investigations have been reported on the skeletal changes following maxillary surgical procedures. The stability following LeFort I osteotomy and maxillary superior repositioning of the maxilla has not been studied extensively. AIM: This study was aimed at determining the surgical changes brought about by superior repositioning of the maxilla by Le Fort I osteotomy and evaluate the stability of the surgical procedure one year following surgery...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28213085/1-10-responsabilit%C3%A3-juridique-du-soignant-en-cas-d%C3%A2-attentat-ou-de-catastrophe
#14
Nicolas Couessurel, Nicolas Genotelle, Christophe Fleury, Patrice Bodenan, Hugues Lefort
No abstract text is available yet for this article.
January 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/28194343/the-effect-of-a-condylar-repositioning-plate-on-condylar-position-and-relapse-in-two-jaw-surgery
#15
Gyu Sik Jung, Taek Kyun Kim, Jeong Woo Lee, Jung Dug Yang, Ho Yun Chung, Byung Chae Cho, Kang Young Choi
BACKGROUND: Numerous condylar repositioning methods have been reported. However, most of them are 2-dimensional or are complex procedures that require a longer operation time and a highly trained surgeon. This study aims to introduce a new technique using a condylar repositioning plate and a centric relation splint to achieve a centric relationship. METHODS: We evaluated 387 patients who had undergone surgery for skeletal jaw deformities. During the operation, a centric relation splint, intermediate splint, final centric occlusion splint, and condylar repositioning plate along with an L-type mini-plate for LeFort I osteotomy or a bicortical screw for bilateral sagittal split ramus osteotomy were utilized for rigid fixation...
January 2017: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/28192237/untargeted-next-generation-sequencing-based-first-line-diagnosis-of-infection-in-immunocompromised-adults-a-multicentre-blinded-prospective-study
#16
Perrine Parize, Erika Muth, Clémence Richaud, Marlène Gratigny, Benoit Pilmis, Arnaud Lamamy, Jean-Luc Mainardi, Justine Cheval, Louise de Visser, Florence Jagorel, Laura Ben Yahia, Geraldine Bamba, Myriam Dubois, Olivier Join-Lambert, Marianne Leruez-Ville, Xavier Nassif, Agnes Lefort, Fanny Lanternier, Felipe Suarez, Olivier Lortholary, Marc Lecuit, Marc Eloit
OBJECTIVE: Infections are the major cause of morbidity and mortality in immunocompromised patients. Improving microbiological diagnosis in these patients is of paramount clinical importance. METHODS: We performed this multicentre, blinded, prospective, proof-of-concept study, to compare untargeted next-generation sequencing with conventional microbiological methods for first-line diagnosis of infection in 101 immunocompromised adults. Patients were followed for 30 days and their blood samples, and in some cases nasopharyngeal swabs and/or biological fluids, were analysed...
February 10, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28160829/-glioblastoma-and-nursing-care-in-neurosurgery
#17
Mathilde Lefort
Nurses in neurosurgical departments play a critical role as they are involved in the first stages of the care pathway of patients with glioblastoma. Indeed, surgery enables a definitive histopathological diagnosis to be established and the size of the tumour to be significantly reduced, thereby improving the prognosis.
February 2017: Revue de L'infirmière
https://www.readbyqxmd.com/read/28157452/activated-%C3%AE-2-integrins-restrict-neutrophil-recruitment-during-murine-acute-pseudomonal-pneumonia
#18
Zachary S Wilson, Lawrence B Ahn, William S Serratelli, Matthew D Belley, Joanne Lomas-Neira, Mehmet Sen, Craig T Lefort
Rapid neutrophil recruitment is critical for the efficient clearance of bacterial pathogens from the lungs. While β2 integrins and their activation are required for neutrophil recruitment from postcapillary venules of the systemic circulation into inflamed tissues, the involvement of integrins in neutrophil recruitment in response to respiratory infection varies between bacterial pathogens. For stimuli eliciting β2 integrin-dependent neutrophil influx, including Pseudomonas aeruginosa, it remains unclear whether the activation of β2 integrins is an essential step in this process...
February 3, 2017: American Journal of Respiratory Cell and Molecular Biology
https://www.readbyqxmd.com/read/28153564/computer-assisted-surgical-planning-and-simulation-for-unilateral-condylar-benign-lesions-causing-facial-asymmetry
#19
Chuan Lu, Dongmei He, Chi Yang, Dong Huang, Edward Ellis
OBJECTIVE: The purpose of this study was to investigate the best surgical sequence for the treatment of unilateral condylar benign lesions causing facial asymmetry by applying computer-assisted surgical planning and simulation. STUDY DESIGN: Computed tomography (CT) data from 12 patients whose maxillary cant was corrected by maintaining the vertical position of the central incisors and equally intruding the long side of the maxilla and extruding the short side were analyzed by ProPlan CMF 1...
April 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28152148/evaluation-of-a-minimally-disruptive-treatment-protocol-for-frontal-sinus-fractures
#20
Sapna A Patel, Angelique M Berens, Karthik Devarajan, Mark E Whipple, Kris S Moe
Importance: Despite common goals of frontal sinus fracture treatment (restoring forehead contour and creating a safe sinus), there remains significant variability in evaluation and treatment. Objective: To describe our experience with a minimally disruptive treatment protocol for the treatment of frontal sinus fractures. Design, Setting, and Participants: Analysis of prospectively collected data from 2010 through 2015 at a level 1 trauma center...
February 2, 2017: JAMA Facial Plastic Surgery
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