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https://www.readbyqxmd.com/read/28088144/more-room-for-microphase-separation-an-extended-study-on-binary-liquids-confined-in-sba-15-cylindrical-pores
#1
Ramona Mhanna, Abdel Razzak Abdel Hamid, Sujeet Dutta, Ronan Lefort, Laurence Noirez, Bernhard Frick, Denis Morineau
The confinement of liquid mixtures in porous channels provides new insight into fluid ordering at the nanoscale. In this study, we address a phenomenon of microphase separation, which appears as a novel fascinating confinement effect for fully miscible binary liquids. We investigate the structure of tert-butanol-toluene mixtures confined in the straight and mono-dispersed cylindrical nanochannels of SBA-15 mesoporous silicates (D = 8.3 nm). Small angle neutron scattering experiments on samples with carefully designed isotopic compositions are performed to systematically vary the scattering length density of the different compounds and assess the radial concentration profile of the confined phases...
January 14, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28076966/evesor-a-model-based-multiparameter-phase-i-trial-to-optimize-the-benefit-toxicity-ratio-of-everolimus-and-sorafenib
#2
Mévidette El-Madani, Olivier Colomban, Michel Tod, Denis Maillet, Julien Peron, Claire Rodriguez-Lafrasse, Osama A Badary, Pierre-Jean Valette, Thibaud Lefort, Philippe Cassier, Siham M El-Shenawy, Ebtehal El-Demerdash, Juliette Hommel-Fontaine, Jerome Guitton, Marie-Claude Gagnieu, Bassant Mm Ibrahim, Catherine Barrois, Gilles Freyer, Benoit You
AIM: This novel multiparameter Phase I study aimed to optimize doses/dosing schedules of everolimus and sorafenib drug combination, based on modeling/simulation (NCT01932177). PATIENTS & METHODS: About 26 patients with solid tumors were treated in four different dosing schedules. Everolimus once daily + sorafenib twice daily were given continuously in arms A and B, and intermittently in arms C (alternating every other week) and D (everolimus continuous and sorafenib 3 days on/4 days off)...
January 12, 2017: Future Oncology
https://www.readbyqxmd.com/read/28073733/antibiotic-therapy-and-staphylococcal-skin-infections-in-a-tropical-malarial-zone-guyana-practices-in-conventional-and-exceptional-situations
#3
S-P Corcostegui, H Lefort, A Dia, V Pommier de Santi, C Carfantan, J Galant, E Lightburne, P Guénot, X Deparis, R Migliani, J-J Morand
A problem of community-acquired Staphylococcus aureus skin infections emerged in the French armed forces in 2004, in a malaria-endemic areas. The high incidence rate led us to evaluate military staff practices. This was a cross-sectional survey of doctors and nurses deployed as officers in French Guyana since 2006. The definition of skin and soft-tissue infection came from the criteria for epidemiological surveillance of the armed forces. We studied the management of antibiotic therapy and its related difficulties...
November 1, 2016: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28072470/sonographic-dynamic-description-of-the-laryngeal-tract-definition-of-quantitative-measures-to-characterize-vocal-fold-motion-and-estimation-of-their-normal-values
#4
Héloïse Bergeret-Cassagne, Diane S Lazard, Muriel Lefort, Siham Hachi, Laurence Leenhardt, Fabrice Menegaux, Gilles Russ, Christophe Trésallet, Frédérique Frouin
Vocal fold motion was analyzed during free breathing using two-dimensional dynamic ultrasound imaging. Two cadavers were first analyzed to define easily identifiable landmarks. Motion of the laryngeal tract was then analyzed in an axial plane. Left and right arytenoids and thyroid cartilage were defined on images corresponding to abduction and adduction of the laryngeal tract. Associated area measurements were established for 50 healthy subjects. All area indices were significantly larger during abduction than adduction...
January 10, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28027972/pelvic-symptoms-body-image-and-regret-after-lefort-colpocleisis-a-long-term-follow-up
#5
Xiaojuan Wang, Yisong Chen, Keqin Hua
STUDY OBJECTIVE: to evaluate the impact of leFort colpocleisis on body image, regret, and pelvic floor symptoms long-term after surgery. DESIGN: retrospective study DESIGN: Classification: Canadian Task Force classification II-2 SETTING: Tertiary university-affiliated hospital PATIENTS: Between April 2011 and April 2015, 334 patients underwent LeFort colpocleisis. INTERVENTION: LeFort colpocleisis MEASUREMENT AND MAIN RESULTS: Patient characteristics (e...
December 24, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28025678/enlightening-the-mechanisms-of-pop-recurrence-after-lefort-colpocleisis-case-report-and-review
#6
REVIEW
Themistoklis Mikos, Mariliz Chatzipanteli, Grigoris F Grimbizis, Basil C Tarlatzis
INTRODUCTION AND HYPOTHESIS: Obliterative procedures for the treatment of pelvic organ prolapse have been reported to have a recurrence rate up to 10%. We present (1) a case report of a patient with prolapse after LeFort colpocleisis and how it was managed in our department, and (2) a review of the literature regarding the types of recurrence after LeFort colpocleisis, their rate and their treatment. METHODS: A 77-year-old woman was treated in our department for recurrence of prolapse through the right lateral channel 6 months after LeFort colpocleisis...
December 26, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/28024773/comprehensive-treatment-approach-for-condylar-hyperplasia-and-mandibular-crowding-with-custom-lingual-braces-and-2-jaw-surgery
#7
Panagiotis G Kyteas, W Stuart McKenzie, Peter D Waite, Chung H Kau
We report on the successful treatment of a 32-year-old woman with condylar hyperplasia and severe mandibular crowding. In addition, her maxilla was canted to the right, her mandibular midline and chin point deviated to the left, and her maxillary canines were missing. The treatment plan included (1) aligning and leveling the teeth in both arches, (2) correcting overbite and overjet, (3) performing LeFort I osteotomy and bilateral split osteotomies, and (4) correcting the malocclusion postsurgically. The orthodontic treatment was performed with custom lingual braces and clear brackets, and virtual surgical planning techniques were used to plan the orthognathic surgery...
January 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28005762/jaw-in-a-day-state-of-the-art-in-maxillary-reconstruction
#8
Christopher M Runyan, Vishal Sharma, David A Staffenberg, Jamie P Levine, Lawrence E Brecht, Leonard H Wexler, David L Hirsch
BACKGROUND: Reconstruction of maxillary defects following tumor extirpation is challenging because of combined aesthetic and functional roles of the maxilla. One-stage reconstruction combining osseous free flaps with immediate osseointegrated implants are becoming the standard for mandibular defects, and have similar potential for maxillary reconstruction. METHODS: A woman with maxillary Ewing sarcoma successfully treated at age 9 with neoadjuvant chemotherapy, right hemimaxillectomy, and obturator prosthetic reconstruction presented for definitive reconstruction, complaining of poor obturator fit, and hypernasality...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28000626/role-of-contrast-enhanced-harmonic-endoscopic-ultrasound-in-submucosal-tumors
#9
REVIEW
Maria Victoria Alvarez-Sanchez, Rodica Gincul, Christine Lefort, Bertrand Napoleon
With the widespread use of endoscopy, gastrointestinal submucosal lesions are now more commonly discovered. Although endoscopic ultrasound (EUS) is superior to all other imaging techniques for the diagnosis of submucosal tumors (SMTs), it is still suboptimal for differentiating hypoechoic lesions arising from the fourth sonographic gastrointestinal wall layer, which encompass tumors with very different prognosis. EUS tissue acquisition has provided with the unique opportunity to obtain histological confirmation, but it is not accurate enough to evaluate the malignant potential of gastrointestinal stromal tumors (GISTs)...
November 2016: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/27994866/facilitating-access-to-the-renal-transplant-waiting-list-does-not-increase-the-number-of-transplantations-comparative-study-of-two-french-regions
#10
Mathilde Lefort, Cécile Vigneau, Annelen Laurent, Saïd Lebbah, Nolwenn Le Meur, Jean-Philippe Jais, Eric Daugas, Sahar Bayat
BACKGROUND: In France, there are important regional disparities of access to the renal transplant waiting list and transplantation. Our objectives were to compare the characteristics of patients with end-stage renal disease (ESRD) of two French regions (Ile-de-France and Bretagne) and to identify determinants of access to the waiting list and subsequent transplantation, with a focus on temporary inactive status (TIS) periods. METHODS: All 18-80-year-old incident patients who started dialysis in Ile-de-France or Bretagne between 2006 and 2009 were included (n = 6160)...
December 2016: Clinical Kidney Journal
https://www.readbyqxmd.com/read/27968969/-care-seen-from-the-other-side
#11
Magali Porlier, Hugues Lefort
Treating an out-of-hospital cardiac arrest (OHCA) is a rare event. The experience of a young nurse who suffered an OHCA reminds us of the importance of activating the chain of survival at the earliest possible moment.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27968967/-nurses-and-health-officers-supporting-the-emergency-operations-command
#12
Franck Pilorget, Hugues Lefort
The health and medical emergency service of a departmental fire and rescue unit is a key element of emergency care in France. Health officers are present in the operations room or in the field. Often a nurse from the fire service, they may also be a doctor or pharmacist. Their mission is to optimise and to anticipate the emergency healthcare response both on a day-to-day basis as well as with extraordinary events involving numerous victims or large-scale technological, natural or terror risks.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27968966/-the-nurse-on-a-remote-mineral-gas-or-oil-extraction-site
#13
Stéphane Roch, Damien Guillou, Hugues Lefort
On mineral, gas or oil extraction sites, medical care is often provided in uncommon conditions by doctors or paramedical staff. Caregivers must fulfil certain requirements, but must also possess the necessary human, technical, physical and psychological qualities to be able to provide high quality care throughout their mission on a remote site.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27968964/-evolution-of-the-nurse-s-role-in-the-management-of-a-cardiac-arrest
#14
Florian Loosli, Alice Hutin, Hugues Lefort, Pierre Carli, Lionel Lamhaut
In France, there are 40 000 sudden deaths each year and the cardiac arrest survival rate is less than 10%. The arrival of extracorporeal cardio pulmonary resuscitation (ECPR) offers hope in the event of refractory cardiac arrest in prehospital care. Extending ECPR programmes requires more scientific evidence, training and an evolution of the role of paramedics.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27968963/-emergency-the-nurse-and-the-patient
#15
Hugues Lefort
At the heart of an emergency, nurses work closely with the patient and centralise the focus of the team work. They provide technical assistance through procedures carried out in an optimal safety framework.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27968962/infirmier-acteur-de-l%C3%A2-urgence
#16
EDITORIAL
Hugues Lefort
No abstract text is available yet for this article.
November 2016: Revue de L'infirmière
https://www.readbyqxmd.com/read/27918377/utility-of-emergency-department-observation-units-for-neurologically-intact-children-with-head-ct-abnormalities-secondary-to-acute-closed-head-injury
#17
Roxanna Lefort, Jill V Hunter, Andrea T Cruz, A Chantal Caviness, Thomas G Luerssen, Aderonke Adekunle-Ojo
OBJECTIVE: The aim of the study was to evaluate the utility of the emergency department observation unit (EDOU) for neurologically intact children with closed head injuries (CHIs) and computed tomography (CT) abnormalities. METHODS: A retrospective cohort study of children aged 0 to 18 years with acute CHI, abnormal head CT, and a Glasgow Coma Scales score of 14 or higher admitted to the EDOU of a tertiary care children's hospital from 2007 to 2010. Children with multisystem trauma, nonaccidental trauma, and previous neurosurgical or coagulopathic conditions were excluded...
December 1, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27906054/is-radical-surgery-of-an-inverted-papilloma-of-the-maxillary-sinus-obsolete-a-case-report
#18
Vedat Yildirim, Niels Christian Pausch, Dirk Halama, Heinz-Theo Lübbers, Ayhan Yildirim
BACKGROUND: Sinonasal inverted papilloma is a locally aggressive tumor arising from the Schneiderian membrane which lines the nasal cavity and paranasal sinuses. Aggressive surgical approaches, such as lateral rhinotomy, were used until recently for complete removal of the inverted papilloma. Currently, endoscopic resection is the gold standard in the treatment of inverted papilloma. However, there are situations that justify an open approach. For example there are studies that report a higher postoperative recurrence rate after endonasal endoscopic resection, particularly in the treatment of recurrent diseases...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27893551/mid-face-degloving-an-alternate-approach-to-extended-osteotomies-of-the-midface
#19
Anantanarayanan Parameswaran, Naveen Kumar Jayakumar, Manikandhan Ramanathan, Hermann F Sailer
Extended osteotomies for mid-face advancement require generous exposure of the anterior maxilla, nasal bones, infraorbital rims, orbital floor, zygoma, and the anterior third of the zygomatic arches. This cannot be obtained with an exclusive transoral approach. Hence, the surgeon is usually compelled to utilize supplemental cutaneous incisions that are a compromise on the purpose behind a cosmetic surgery. In order to alleviate the need for such compromise, the authors advocate the mid face degloving approach for extended osteotomies at Lefort II and Lefort III levels...
January 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27852744/integrin-cross-talk-regulates-the-human-neutrophil-response-to-fungal-%C3%AE-glucan-in-the-context-of-the-extracellular-matrix-a-prominent-role-for-vla3-in-the-antifungal-response
#20
Courtney M Johnson, Xian M O'Brien, Angel S Byrd, Valentina E Parisi, Alex J Loosely, Wei Li, Hadley Witt, Hafeez M Faridi, Craig T Lefort, Vineet Gupta, Minsoo Kim, Jonathan S Reichner
Candida albicans infection produces elongated hyphae resistant to phagocytic clearance compelling alternative neutrophil effector mechanisms to destroy these physically large microbial structures. Additionally, all tissue-based neutrophilic responses to fungal infections necessitate contact with the extracellular matrix (ECM). Neutrophils undergo a rapid, ECM-dependent mechanism of homotypic aggregation and NETosis in response to C. albicans mediated by the β2 integrin, complement receptor 3 (CR3, CD11b/CD18, αMβ2)...
January 1, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
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