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Stéphane Foucher, David Drexler, Jean-Baptiste Le Loch, François Braun, Hugues Lefort
No abstract text is available yet for this article.
May 2018: Soins; la Revue de Référence Infirmière
Thibaut Bila, Myriam Honnorat, Paul-Vincent Martin, Yvan Fronty, Hugues Lefort
No abstract text is available yet for this article.
May 2018: Revue de L'infirmière
Fabien Lefebvre, Benjamin Baudin, Antoine Bronstein, Hugues Lefort, Frank Peduzzi
Nursing practice on a ship involves certain risks and constraints inherent to the facilities themselves and the maritime environment. The response in the case of a medical incident at sea is guided by an organisation adapted to these constraints, overseen by a specific regulatory body. Different entities, players and resources may be involved depending on the diverse situations encountered.
May 2018: Revue de L'infirmière
Sophie Carter, Stéphanie Miard, Louise Boivin, Sandrine Sallé-Lefort, Frédéric Picard
Several studies have suggested that signals emerging from white adipose tissue can contribute to the control of longevity. In turn, aging is associated with perturbed regulation and partitioning of fat depots and insulin resistance. However, the exact mechanisms involved in these relationships remain undetermined. Using RAP-PCR on adipose tissue of young and old male mice coupled with qPCR validation, we have uncovered the long non-coding RNA Malat1 as a gene robustly downregulated in visceral white adipose tissue (vWAT) during normal aging in male mice and men...
2018: PloS One
Nolwenn Le Meur, Cécile Vigneau, Mathilde Lefort, Saïd Lebbah, Jean-Philippe Jais, Eric Daugas, Sahar Bayat
Background Patients with chronic diseases, like patients with end-stage renal disease (ESRD), have long history of care driven by multiple determinants (medical, social, economic, etc.). Although in most epidemiological studies, analyses of health care determinants are computed on single health care events using classical multivariate statistical regression methods. Only few studies have integrated the concept of treatment trajectories as a whole and studied their determinants. Methods All 18- to 80-year-old incident ESRD patients who started dialysis in Ile-de-France or Bretagne between 2006 and 2009 and could be followed for a period of 48 months after initiation of a renal replacement therapy were included ( n = 5568)...
January 1, 2018: Statistical Methods in Medical Research
Marc Renom-Carrasco, Laurent Lefort
To accelerate the discovery of new or improved homogeneous catalysts, research groups in industry and academia have embraced high throughput experimentation (HTE). Such methodologies consist of preparing and testing large numbers of catalysts in parallel. Homogeneous metal catalysts are very well-suited for HTE, since in many cases, they can be prepared by simply mixing a metal precursor and a ligand. However, an HTE program requires a large set of chemically diverse ligands, i.e. a ligand library. In this review, we describe five different approaches for assembling ligand libraries based on an extensive survey of the literature...
May 8, 2018: Chemical Society Reviews
M Schwaiger, J Wallner, W Zemann, M Feichtinger
Orbital tumours, located in the medial extraconal and intraconal compartment of the orbit, represent a challenge, with regard to surgical exposure. In the present paper removal of a cavernous haemangioma, located in the medial intraconal compartment was accomplished by combining lateral orbitotomy, midfacial degloving and LeFort-I osteotomy. Resection of the tumour could be performed under direct vision. Surgical exposure and removal of the lesion were obtained, without causing damage to surrounding tissues...
April 24, 2018: International Journal of Oral and Maxillofacial Surgery
Isabelle Klein, Axelle Montels, Kilian Bertho, Clément Derkenne, Hugues Lefort
No abstract text is available yet for this article.
April 2018: Soins; la Revue de Référence Infirmière
Zakaria Jalal, Sébastien Hascoët, Céline Gronier, François Godart, Lucia Mauri, Claire Dauphin, Bruno Lefort, Matthias Lachaud, Dominique Piot, Marie-Lou Dinet, Yael Levy, Alain Fraisse, Caroline Ovaert, Xavier Pillois, Jean-René Lusson, Jérôme Petit, Alban-Elouen Baruteau, Jean-Benoit Thambo
OBJECTIVES: This study sought to assess procedural characteristics, early clinical outcome, and long-term complications after transcatheter closure of atrial septal defect (ASD) in children. BACKGROUND: Transcatheter closure has become the preferred strategy in most cases of isolated secundum ASD. However, reported experience in the pediatric population is limited. METHODS: A 1998 to 2016 retrospective multicenter study was performed in 9 French tertiary institutions...
April 23, 2018: JACC. Cardiovascular Interventions
Shokei Matsumoto, Taku Akashi, Kei Hayashida, Kazuhiko Sekine, Tomohiko Orita, Tomohiro Funabiki, Mitsuhide Kitano
INTRODUCTION: Transcatheter arterial embolization (TAE) has gained importance in the management of maxillofacial fractures with life-threating hemorrhage (MFH). However, clinical evidence supporting the use of TAE has not been clearly established in the literature. Therefore, we evaluated the effectiveness of TAE for MFH, based on data obtained from the Japan Trauma Data Bank. METHODS: Patients were identified from Japan Trauma Data Bank entries for the years 2004 to 2014...
June 2018: Annals of Plastic Surgery
A Trubiroha, P Gillotay, N Giusti, D Gacquer, F Libert, A Lefort, B Haerlingen, X De Deken, R Opitz, S Costagliola
The foregut endoderm gives rise to several organs including liver, pancreas, lung and thyroid with important roles in human physiology. Understanding which genes and signalling pathways regulate their development is crucial for understanding developmental disorders as well as diseases in adulthood. We exploited unique advantages of the zebrafish model to develop a rapid and scalable CRISPR/Cas-based mutagenesis strategy aiming at the identification of genes involved in morphogenesis and function of the thyroid...
April 4, 2018: Scientific Reports
Qu Zhenyu, Wang Qian, Zhao Yan, Sheng Lanlan, Ma Weidong, Qu Weiguo
OBJECTIVE: This study aimed to investigate the application of an osteotomy template and a repositioning template manufactured by three-dimensional (3D) printing technique in maxillary LeFortⅠosteotomy. METHODS: The patient group consisted of eight patients with maxillary hypoplasia who underwent LeFortⅠosteotomy. The mean age at the time of surgery was 25.6 years old. All patients were scanned using cone beam computed tomography (CBCT) to create a 3D model of the maxillary...
February 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
T Goulenok, D Chopin, V De Lastours, V Zarrouk, R Lepeule, B Fantin, A Lefort
INTRODUCTION: Vaccination against influenza virus and Streptococcus pneumoniae is a global health priority and authorities, on the basis of recent publications, have recently updated French recommendations. The aim of this study was to describe the influenzae and pneumococcal vaccination's rate in an internal medicine ward. MATERIAL AND METHODS: All patients consecutively hospitalized during a 10 week-period in an internal medicine ward were included. The reasons for non-vaccination and the impact of an educational program for corrective measures were reported...
March 20, 2018: La Revue de Médecine Interne
Jérôme Pallier, Clément Derkenne, Sébastien Ramade, Stéphane Travers, Hugues Lefort
No abstract text is available yet for this article.
March 2018: Soins; la Revue de Référence Infirmière
Elbert E Vaca, Sergey Y Turin, Arun K Gosain
Difficulty with speech intelligibility in Mobius syndrome patients due to bilabial incompetence is common yet rarely discussed. We present a patient with Mobius syndrome who underwent counterclockwise LeFort I impaction to improve her labial competence. In addition, we present a literature review of management strategies for labial incompetence correction in Mobius patients. At 7-year follow-up after LeFort 1 impaction, the patient reports improvement in speech intelligibility, specifically regarding the ability to pronounce bilabial consonants...
January 1, 2018: Cleft Palate-craniofacial Journal
Thibaut Bila, Pierre-Éric Schwartzbrod, Paul-Vincent Martin, Yvan Fronty, Hugues Lefort
No abstract text is available yet for this article.
March 2018: Revue de L'infirmière
Elizabeth G Mann, Margaret B Harrison, Sandra LeFort, Elizabeth G VanDenKerkhof
Individuals with chronic pain with neuropathic characteristics (CPNC) describe a different pain experience compared with those with chronic pain without neuropathic characteristics (CP). The aim of this study was to describe and compare pain, self-management strategies, and satisfaction with ability to control pain between adults with CPNC versus CP. Seven hundred and ten community-dwelling adults with chronic pain participated in a cross-sectional survey. CPNC was defined as a score ≥12 on the Self-Report Leeds Assessment of Neuropathic Symptoms and Signs Pain Scale...
March 1, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
Sophie Carter, Stéphanie Miard, Alexandre Caron, Sandrine Sallé-Lefort, Philippe St-Pierre, Fernando Forato Anhê, Emilie Lavoie-Charland, Pascale Blais-Lecours, Marie-Claude Drolet, Julie S Lefebvre, Julie Lacombe, Yves Deshaies, Jacques Couet, Mathieu Laplante, Mathieu Ferron, Yohan Bossé, André Marette, Denis Richard, David Marsolais, Frédéric Picard
The current demographic shift toward an aging population has led to a robust increase in the prevalence of age-associated metabolic disorders. Interestingly, recent studies have demonstrated that the etiology of obesity-related insulin resistance developed upon aging differs from that induced by high-calorie diets. Whereas the role of adaptive immunity on the changes in energy metabolism driven by nutritional challenges has gained attention in the past years, its impact upon aging remains mostly unknown. Here, we found that follicular B2 lymphocytes and expression levels of the B cell-specific transcriptional coactivator OcaB increase with age in spleen and in intra-abdominal epididymal white adipose tissue (eWAT), concomitantly with higher circulating levels of immunoglobulin G (IgG) and impaired glucose homeostasis...
March 1, 2018: Diabetes
Florence Zylbersztejn, Mario Flores-Violante, Thibault Voeltzel, Franck-Emmanuel Nicolini, Sylvain Lefort, Véronique Maguer-Satta
The microenvironment (niche) governs the fate of stem cells (SCs) by balancing self-renewal and differentiation. Increasing evidence indicates that the tumor niche plays an active role in cancer, but its important properties for tumor initiation progression and resistance remain to be identified. Clinical data show that leukemic stem cell (LSC) survival is responsible for disease persistence and drug resistance, probably due to their sustained interactions with the tumor niche. Bone morphogenetic protein (BMP) signaling is a key pathway controlling stem cells and their niche...
May 2018: Experimental Hematology
David Drexler, Kilian Bertho, Patrick Walkoviak, Clément Derkenne, Hugues Lefort
No abstract text is available yet for this article.
January 2018: Soins; la Revue de Référence Infirmière
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