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https://www.readbyqxmd.com/read/28409045/odontogenic-cyst-with-verrucous-proliferation-exhibiting-melanin-pigmentation
#1
Nidhi Manaktala, Karen Boaz, Krupa Mehta Soni, Srikant Natarajan, Junaid Ahmed, Keshava Bhat, Nandita Kottieth Pallam, Amitha Juanita Lewis
Verrucous proliferation arising from odontogenic cysts is a rare entity. We report an unusual case of an infected odontogenic cyst with verrucous proliferation and melanin pigmentation in a 13-year-old male patient who presented with an intraoral swelling in relation to impacted teeth 26 and 27. The enucleated lesion was diagnosed as an odontogenic keratocyst and the patient died within two years of presentation due to multiple recurrences. The clinical, radiological, and microscopic features of the lesion are presented with an attempt to discuss the etiopathogenesis...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28390759/tube-decompression-for-staged-treatment-of-a-calcifying-odontogenic-cyst-a-case-report
#2
Hany A Emam, Judson Smith, Ashleigh Briody, Courtney A Jatana
The calcifying odontogenic cyst is a rare developmental odontogenic lesion with a distinguishing cystic lining containing "ghost" epithelial cells. The variation in clinical, radiographic, and histologic findings makes the treatment decision difficult for these lesions. There are very few reports on treatment, with enucleation and curettage being the standard surgical method of choice for the cystic type and excision of the tumor for the solid type. A 2-stage surgical approach consisting of initial decompression with tube placement followed by a secondary procedure of enucleation and curettage is common for other large odontogenic cysts, such as dentigerous and odontogenic keratocysts...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28388515/long-term-observation-of-a-large-keratocystic-odontogenic-tumour-of-the-mandible-treated-by-a-single-enucleation-procedure-a-case-report-and-literature-review
#3
Tobias L Pittl, Marius Meier, Paul Hakl, Walter Sutter, Dritan Turhani
INTRODUCTION: Keratocystic odontogenic tumours (KCOTs) are benign lesions of the jaw that are characterised by expansive growth and high rates of recurrence. Herein, we present a novel minimally invasive method for the surgical treatment of KCOTs. CASE PRESENTATION: We present a 49-year-old woman with a rare, large KCOT of the mandible extending from tooth 37 to tooth 47. A single enucleation procedure was selected as the surgical technique combined with a titanium plate...
March 23, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28377093/decompression-of-keratocystic-odontogenic-tumors-leading-to-increased-fibrosis-but-without-any-change-in-epithelial-proliferation
#4
Sarah Awni, Brendan Conn
OBJECTIVE: The aim of this study was to investigate whether decompression treatment induces changes in the histology or biologic behavior of keratocystic odontogenic tumor (KCOT). STUDY DESIGN: Seventeen patients with KCOT underwent decompression treatment with or without enucleation. Histologic evaluation and immunohistochemical expression of p53, Ki-67, and Bcl-2 were analyzed by using conventional microscopy. RESULTS: KCOT showed significantly increased fibrosis (P = ...
December 30, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28341089/corrigendum-to-malignant-transformation-of-keratocystic-odontogenic-tumor-two-case-reports-american-journal-of-otolaryngology-34-2013-357-361
#5
Bernard Tan, Sok Yan Tay, Lee Shermin, Kwa Chong Teck, Poon Choy Yoke, Christopher Goh, Abhilash Balakrishnan
No abstract text is available yet for this article.
March 21, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28329640/diagnostic-parameters-of-children-with-basal-cell-carcinoma-nevus-syndrome
#6
Fariha T Siddiqui
Basal Cell Carcinoma Nevus Syndrome (BCCNS) is a multi-system genetic disease characterized by the development of multiple basal cell carcinomas (BCCs), macrocephaly, medulloblastomas, jaw keratocysts, and coarse facial features, amongst other symptoms. The major and minor criteria for adults with BCCNS are often extrapolated for children, however, little is known about the disease presentation of children with BCCNS. Our study focused on bringing the pediatric presentation of BCCNS to light. To the best of our knowledge, we are the first to investigate BCCNS and its medical impact on children...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28328109/a-cohort-study-of-gorlin-syndrome-with-emphasis-on-standardised-phenotyping-and-quality-of-life-assessment
#7
Aamira J Huq, Michael Bogwitz, Alexandra Gorelik, Ingrid M Winship, Susan M White, Alison H Trainer
BACKGROUND: Gorlin syndrome (Nevoid Basal Cell Carcinoma Syndrome) is a rare genetic predisposition to basal cell carcinomas (BCCs), keratocysts of the jaw and calcification of the falx cerebri amongst other clinical features. With the advent of sonic hedgehog inhibitors for the treatment of BCCs, it is timely to establish a cohort of individuals with Gorlin syndrome and collect standardised phenotypic information on these individuals. Moreover, the health-related quality of life (QoL) in individuals with Gorlin syndrome is not well studied...
March 22, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28316917/a-comparative-study-of-syndecan-1-expression-in-different-odontogenic-tumors
#8
Shahroo Etemad-Moghadam, Mojgan Alaeddini
BACKGROUND: Expression of various cellular/molecular factors change during the course of tumor formation from odontogenic tissues of the tooth germ. Evaluation of these factors can help provide a better perception of the tumorigenesis and biologic behavior of odontogenic tumors (OTs). Syndecan-1 is a heparan sulfate proteoglycan which has not been extensively investigated in these lesions. The objective of the present study was to assess the immunohistochemical expression of CD138 in adenomatoid odontogenic tumor (AOT), ameloblastic fibroma (AF) and odontogenic myxoma (OM) and to compare it with ameloblastoma and keratocystic odontogenic tumor (KCOT)...
January 2017: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/28280759/immunohistochemical-comparison-of-the-expression-of-cd34-and-cd105-in-odontogenic-keratocyst-and-dentigerous-cyst
#9
Shokoofeh Jamshidi, Massoumeh Zargaran, Ghodratollah Roshanaei, Fatemeh Hadadi, Ali Dehghani Nazhvani
STATEMENT OF THE PROBLEM: Odontogenic keratocyst (OKC) is a developmental odontogenic cyst with specific histopathological features, high recurrence rate, and aggressive clinical behavior. Angiogenesis might be considered as an important factor for the growth, expansion, and distribution of this lesion. PURPOSE: The aim of the present study was to determine the mean vascular densities (MVD) of OKCs and dentigerous cysts to evaluate their relationship with the biologic behavior of these lesions...
March 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28274671/second-opinion-oral-pathology-referrals-in-new-zealand
#10
B Seo, H M Hussaini, A M Rich
Referral for a second opinion is an important aspect of pathology practice, which reduces the rate of diagnostic error and ensures consistency with diagnoses. The Oral Pathology Centre (OPC) is the only specialist oral diagnostic centre in New Zealand. OPC provides diagnostic services to dentists and dental specialists throughout New Zealand and acts as a referral centre for second opinions for oral pathology specimens that have been sent to anatomical pathologists. The aim of this study was to review second opinion referral cases sent to the OPC over a 15-year period and to assess the levels of concordance between the original and final diagnoses...
April 2017: Pathology
https://www.readbyqxmd.com/read/28273221/keratocystic-odontogenic-tumor
#11
Brenda DE Souza Moura, Maria Aparecida Cavalcante, Wagner Hespanhol
to evaluate the frequency of keratocystic odontogenic tumor (KOT) in the Oral Surgery Service (OSS) of the University Hospital Clementino Fraga Filho of the Federal University of Rio de Janeiro (HUCFF / UFRJ), with respect to recurrence rate, gender, age of recurrence and location of the injury Methods: clinical records were reviewed and histopathological reports of KOT patients of the HUCFF/UFRJ between 2002 and 2012. Patients diagnosed with KOT were divided into two groups for the occurrence of relapse: positive (n=6) and negative (n=19) Results: regarding the location, there was a predilection for the mandible...
December 2016: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28238093/role-of-hif-1%C3%AE-and-caspase-3-in-cystogenesis-of-odontogenic-cysts-and-tumors
#12
Natacha M M da Costa, Adriane S de Siqueira, André L R Ribeiro, Maria S da Silva Kataoka, Ruy G Jaeger, Sérgio M de Alves-Júnior, Andrew M Smith, João de Jesus Viana Pinheiro
OBJECTIVES: Odontogenic cysts and tumors are the most relevant lesions that affect the gnathic bones. These lesions have in common the formation of cystic areas and this common feature may suggest involvement of similar mechanisms. The hypoxia inducible factor 1 alpha (HIF-1α), a responsive protein to hypoxia and caspase-3, an irreversible apoptosis marker, may contribute to cyst formation. Thus, this study aimed to investigate the immunoexpression of these proteins in odontogenic cysts and tumors...
February 25, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28222389/correlation-between-ploidy-status-using-flow-cytometry-and-nucleolar-organizer-regions-in-benign-and-malignant-epithelial-odontogenic-tumors
#13
Sarah Ahmed Mohamed Mahmoud, Dalia Hussein El-Rouby, Safa Fathy Abd El-Ghani, Omnia Mohamed Badawy
OBJECTIVE: Differentiation between the aggressive benign odontogenic tumors and their malignant counterparts is controversial and difficult. While flow cytometry (FCM) allowed DNA analysis in neoplasia, argyrophilic organizer regions (AgNORs) number and/or size in a nucleus are correlated with the ribosomal gene activity and therefore with cellular proliferation. The aim of this research was to study the diagnostic accuracy of FCM and AgNORs staining in differentiating between benign and malignant epithelial odontogenic tumors and to correlate between these two interventions...
February 14, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28209002/ability-of-oral-and-maxillofacial-surgery-residents-in-diagnosing-jaw-cysts-a-retrospective-20-years-study
#14
Hassan Mohajerani, Mohammad Esmaeelinejad, Reza Mofidian
INTRODUCTION: Diagnosis of odontogenic cysts despite of their benign nature is a critical and challenging problem especially among undergraduate and postgraduate students. AIM: This study aimed to evaluate the capability of oral and maxillofacial surgery residents in diagnosing odontogenic cysts. MATERIALS AND METHODS: This cross-sectional study was executed on 312 patient records over the past 20 years since October 1995 till December 2014 in Taleghani Hospital, Tehran, Iran...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28199753/tnf-%C3%AE-308g-a-and-tnf-r1-36a-g-single-nucleotide-polymorphisms-are-strong-risk-factors-for-odontogenic-keratocystic-tumor-development
#15
Branislav Ilic, Nadja Nikolic, Miroslav Andric, Drago Jelovac, Biljana Milicic, Tanja Jozic, Slobodan Krstic, Jelena Milasin
BACKGROUND: Polymorphisms in genes encoding tumor necrosis factor-α (TNF-α) and its receptor TNF-R1 have been shown to affect one person's susceptibility to develop certain neoplastic diseases. The aim of the present association study was to investigate whether single nucleotide polymorphisms (SNPs) in TNF-α (-308G>A) and TNF-R1 (36A>G) genes modulate the susceptibility for keratocystic odontogenic tumors (KCOTs) development in Serbian patients. METHODS: Genotyping was performed in 60 KCOT patients and 125 healthy individuals, using polymerase chain reaction/restriction fragment length polymorphism analysis...
April 2017: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/28187891/automated-classification-of-maxillofacial-cysts-in-cone-beam-ct-images-using-contourlet-transformation-and-spherical-harmonics
#16
Fatemeh Abdolali, Reza Aghaeizadeh Zoroofi, Yoshito Otake, Yoshinobu Sato
BACKGROUND AND OBJECTIVE: Accurate detection of maxillofacial cysts is an essential step for diagnosis, monitoring and planning therapeutic intervention. Cysts can be of various sizes and shapes and existing detection methods lead to poor results. Customizing automatic detection systems to gain sufficient accuracy in clinical practice is highly challenging. For this purpose, integrating the engineering knowledge in efficient feature extraction is essential. METHODS: This paper presents a novel framework for maxillofacial cysts detection...
February 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28174367/collagen-and-its-role-in-predicting-the-biological-behavior-of-odontogenic-lesions
#17
Pavan G Kulkarni, M Aruna Kumari, Abhishek Jahagirdar, Srk Nandan, Shyam Prasad Reddy D, M Keerthi
INTRODUCTION: Odontogenic cysts and tumors have variable recurrence rates. Recurrence rate is mainly due to the activity of the epithelium. The epithelium of these lesions has been investigated extensively in regard to their role in proliferative and aggressive behavior of the lesions. However, the role of the connective tissue wall in their behavior has not been studied as extensively. Collagen is an essential part of the connective tissue as a whole and fibrous wall of cystic lesions especially...
February 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28160576/the-relative-frequency-of-odontogenic-tumors-a-study-of-376-cases-in-a-brazilian-population
#18
R Lima-Verde-Osterne, E Turatti, R Cordeiro-Teixeira, R Barroso-Cavalcante
BACKGROUND: Odontogenic tumors (OTs) are rare lesions, exclusive of the jaws, that are derived from epithelial and/or ectomesenchymal elements of the tooth-forming apparatus. Their biological behavior is heterogeneous, including hamartomatous tissue proliferation, benign nonaggressive and aggressive neoplasms, and malignant tumors with metastatic capacity. The aim of this study was to describe the relative frequency of odontogenic tumors in a Brazilian population. In addition, a review of the literature identified studies on odontogenic tumors that follow the 2005 World Health Organization...
March 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28153133/odontogenic-cysts-and-neoplasms
#19
REVIEW
Elizabeth Ann Bilodeau, Bobby M Collins
This article reviews a myriad of common and uncommon odontogenic cysts and tumors. The clinical presentation, gross and microscopic features, differential diagnosis, prognosis, and diagnostic pitfalls are addressed for inflammatory cysts (periapical cyst, mandibular infected buccal cyst/paradental cyst), developmental cysts (dentigerous, lateral periodontal, glandular odontogenic, orthokeratinized odontogenic cyst), benign tumors (keratocystic odontogenic tumor, ameloblastoma, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibroma and fibroodontoma, odontoma, squamous odontogenic tumor, calcifying cystic odontogenic tumor, primordial odontogenic tumor, central odontogenic fibroma, and odontogenic myxomas), and malignant tumors (clear cell odontogenic carcinoma, ameloblastic carcinoma, ameloblastic fibrosarcoma)...
March 2017: Surgical Pathology Clinics
https://www.readbyqxmd.com/read/28149484/maxillary-peripheral-keratocystic-odontogenic-tumor-a-clinical-case-report
#20
María Del Carmen Vázquez-Romero, María de Los Angeles Serrera-Figallo, Javier Alberdi-Navarro, Javier Cabezas-Talavero, Manuel-María Romero-Ruiz, Daniel Torres-Lagares, Jose-Manuel Aguirre-Urizar, Jose-Luis Gutiérrez-Pérez
The keratocystic odontogenic tumor is a benign odontogenic cystic neoplasia characterized by its thin, squamous epithelium with superficial parakeratosis. It has the potential for infiltration and local aggressiveness and has a high rate of recurrence. This neoplasia is predominantly found in males and people of white origin. The mandible is the most frequently involved site, in particular the third molar region, mandibular angle, and ramus. It has a mandible-maxilla ratio of 2:1. Only about twenty cases of peripheral keratocystic odontogenic tumors (PKCOT) have been reported in the international literature...
January 2017: Journal of Clinical and Experimental Dentistry
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