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Cynthia Gyamfi-Bannerman

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https://www.readbyqxmd.com/read/29791953/past-and-present-a-review-of-antenatal-corticosteroids-and-recommendations-for-late-preterm-birth-steroids
#1
C Luke Dixon, Gloria Too, George R Saade, Cynthia Gyamfi-Bannerman
Since 1972, the beneficial neonatal effects of antenatal corticosteroids (ACSs) have been repeatedly demonstrated in pregnancies at risk of preterm birth before 34 weeks' gestation. While ACS utilization before 34 weeks has been high since the 1990s, knowledge gaps regarding the risks and benefits of ACS continue to exist. Recent evidence has been published regarding the benefit of ACS in the late preterm period. This review addresses the evidence and knowledge gaps for ACS use before and after 34 weeks' gestation...
May 23, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29752934/postpartum-hemorrhage-outcomes-and-race
#2
Cynthia Gyamfi-Bannerman, Sindhu K Srinivas, Jason D Wright, Dena Goffman, Zainab Siddiq, Mary E D'Alton, Alexander M Friedman
BACKGROUND: How race is associated with adverse outcomes in the setting of postpartum hemorrhage is not well characterized. OBJECTIVE: The objective of this study was to assess how race is associated with adverse maternal outcomes in the setting of postpartum hemorrhage. STUDY DESIGN: This retrospective cohort study utilized the National (Nationwide) Inpatient Sample (NIS) from the Agency for Healthcare Research and Quality for the years 2012 to 2014...
May 9, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29747882/antenatal-corticosteroids-who-should-we-be-treating
#3
REVIEW
Whitney A Booker, Cynthia Gyamfi-Bannerman
Antenatal corticosteroids remain one of the crucial interventions in those at risk for imminent preterm birth. Therapeutic benefits include reducing major complications of prematurity such as respiratory distress syndrome, intraventricular hemorrhage, and necrotizing enterocolitis, as well as an overall decrease in neonatal deaths. Optimal reductions in neonatal morbidity and mortality require a thoughtful review of the timing of administration. In addition, a thorough understanding is required of which patients maximally benefit from this intervention in the management and counseling of those at risk for preterm birth...
June 2018: Clinics in Perinatology
https://www.readbyqxmd.com/read/29738748/femur-sparing-pattern-of-abnormal-fetal-growth-in-pregnant-women-from-new-york-city-after-maternal-zika-virus-infection
#4
Christie L Walker, Audrey A Merriam, Eric O Ohuma, Manjiri K Dighe, Michael Gale, Lakshmi Rajagopal, Aris T Papageorghiou, Cynthia Gyamfi-Bannerman, Kristina M Adams Waldorf
BACKGROUND: Zika virus (ZIKV) is a mosquito-transmitted flavivirus, which can induce fetal brain injury and growth restriction following maternal infection during pregnancy. Prenatal diagnosis of ZIKV-associated fetal injury in the absence of microcephaly is challenging due to an incomplete understanding of how maternal ZIKV infection affects fetal growth and the use of different sonographic reference standards around the world. We hypothesized that skeletal growth is unaffected by ZIKV infection and that the femur length can represent an internal standard to detect growth deceleration of the fetal head and/or abdomen by ultrasound...
May 5, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29702708/prolong-clinical-study-protocol-hydroxyprogesterone-caproate-to-reduce-recurrent-preterm-birth
#5
Sean C Blackwell, Cynthia Gyamfi-Bannerman, Joseph R Biggio, Suneet P Chauhan, Brenna L Hughes, Judette M Louis, Tracy Manuck, Hugh S Miller, Anita F Das, Robert Birch, Michael J Jozwiakowski
The objective of this commentary is to describe the background, rationale, and methods of the PROLONG (Progestin's Role in Optimizing Neonatal Gestation) trial, which is a multicenter, multinational, placebo-controlled, randomized clinical trial (RCT) designed to assess the safety and efficacy of Makena (hydroxyprogesterone caproate injection, 250 mg/mL) in reducing the risk of preterm birth (PTB) and neonatal morbidity/mortality in women pregnant with a singleton gestation who had a previous singleton spontaneous PTB...
April 27, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29409815/fusobacterium-nucleatum-and-adverse-pregnancy-outcomes-epidemiological-and-mechanistic-evidence
#6
REVIEW
Emilie L Vander Haar, Jeewon So, Cynthia Gyamfi-Bannerman, Yiping W Han
Fusobacterium nucleatum is a Gram-negative anaerobic oral commensal associated with periodontal disease. F. nucleatum has been implicated in a wide spectrum of systemic diseases, including oral, gastro-intestinal, rheumatologic, and vascular pathologies. As pregnancy risk has been linked to periodontal disease, there has also been significant research into the effects of periodontal disease on adverse pregnancy outcomes. This article reviews the epidemiological and mechanistic evidence of the role of F. nucleatum in adverse pregnancy outcomes...
April 2018: Anaerobe
https://www.readbyqxmd.com/read/29191289/introduction-current-preterm-birth-prevention-strategies-part-2
#7
EDITORIAL
Joy Vink, Cynthia Gyamfi-Bannerman
No abstract text is available yet for this article.
December 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/29183819/smfm-special-report-putting-the-m-back-in-mfm-reducing-racial-and-ethnic-disparities-in-maternal-morbidity-and-mortality-a-call-to-action
#8
Joses A Jain, Lorene A Temming, Mary E D'Alton, Cynthia Gyamfi-Bannerman, Methodius Tuuli, Judette M Louis, Sindhu K Srinivas, Aaron B Caughey, William A Grobman, Mark Hehir, Elizabeth Howell, George R Saade, Alan T N Tita, Laura E Riley
Racial and ethnic disparities in maternal morbidity and mortality rates are an important public health problem in the United States. Because racial and ethnic minorities are expected to comprise more than one-half of the US population by 2050, this issue needs to be addressed urgently. Research suggests that the drivers of health disparities occur at 3 levels: patient, provider, and system. Although we have recognized this issue and identified elements that contribute to it, knowledge must be converted into action to address it...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29108444/outcomes-after-periviable-ultrasound-indicated-cerclage
#9
Daphnie Drassinower, Elizabeth Coviello, Helain J Landy, Cynthia Gyamfi-Bannerman, Annette Perez-Delboy, Alexander M Friedman
BACKGROUND: Cerclage placed for a sonographically short cervix has been shown to reduce the risk of preterm delivery in women with a history of prior preterm birth. While short cervix is traditionally placed before viability, the threshold gestational age at which viability is achieved continues to decrease, and, as a result, a larger subset of women may be ineligible to receive this potentially beneficial procedure. OBJECTIVE: To evaluate the association between obstetric outcomes and perioperative complications after placement of an ultrasound-indicated cerclage at periviability compared to placement in the previable period...
November 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29079144/society-for-maternal-fetal-medicine-smfm-consult-series-44-management-of-bleeding-in-the-late-preterm-period
#10
Cynthia Gyamfi-Bannerman
Third-trimester bleeding is a common complication arising from a variety of etiologies, some of which may initially present in the late preterm period. Previous management recommendations have not been specific to this gestational age window, which carries a potentially lower threshold for delivery. The purpose of this document is to provide guidance on management of late preterm (34 0/7-36 6/7 weeks of gestation) vaginal bleeding. The following are Society for Maternal-Fetal Medicine recommendations: (1) we recommend delivery at 36-37 6/7 weeks of gestation for stable women with placenta previa without bleeding or other obstetric complications (GRADE 1B); (2) we do not recommend routine cervical length screening for women with placenta previa in the late preterm period due to a lack of data on an appropriate management strategy (GRADE 2C); (3) we recommend delivery between 34 and 37 weeks of gestation for stable women with placenta accreta (GRADE 1B); (4) we recommend delivery between 34 and 37 weeks of gestation for stable women with vasa previa (GRADE 1B); (5) we recommend that in women with active hemorrhage in the late preterm period, delivery should not be delayed for the purpose of administering antenatal corticosteroids (GRADE 1B); (6) we recommend that fetal lung maturity testing should not be used to guide management in the late preterm period when an indication for delivery is present (GRADE 1B); and (7) we recommend that antenatal corticosteroids should be administered to women who are eligible and are managed expectantly if delivery is likely within 7 days, the gestational age is between 34 0/7 and 36 6/7 weeks of gestation, and antenatal corticosteroids have not previously been administered (GRADE 1A)...
January 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29074002/novel-thoughts-on-preterm-birth-research-proceedings-of-the-13th-annual-preterm-birth-international-collaborative-prebic-meeting
#11
REVIEW
Cynthia Gyamfi-Bannerman, Ramkumar Menon, Elizabeth A Bonney, Siobhan M Dolan, Mark Johnson, Ronald F Lamont, Sam Mesiano, Amy P Murtha, Leslie Myatt, Indira Mysorekar, Scott M Williams, Nanbert Zhong, Hanns Helmer
No abstract text is available yet for this article.
November 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/29020697/effect-of-maternal-age-and-fetal-number-on-the-risk-of-hypertensive-disorders-of-pregnancy
#12
Devin D Smith, Audrey A Merriam, Julley Jung, Cynthia Gyamfi-Bannerman
OBJECTIVE:  Our primary objective was to compare the differential contribution of fetal number and maternal age to the risk of hypertensive disorders of pregnancy (HDP). STUDY DESIGN:  This was a secondary analysis of a large study of primary cesarean delivery. Women with singleton, twin, or triplet gestations were included. Women were divided into groups based on fetal number and maternal age. The primary outcome was HDP. A logistic regression model was fit to adjust for confounders...
February 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/28865982/epidemiology-of-preterm-birth
#13
REVIEW
Stephanie E Purisch, Cynthia Gyamfi-Bannerman
Preterm birth is a worldwide epidemic with a global incidence of 15 million per year. Though rates of preterm birth in the United States have declined over the last decade, nearly 1 in 10 babies is still born preterm. The incidence, gestational age, and underlying etiology of preterm birth is highly variable across different racial and ethnic groups and geographic boundaries. In this article, we review the epidemiology of preterm birth in the United States and globally, with a focus on temporal trends and racial, ethnic, and geographic disparities...
November 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28818299/current-preterm-birth-prevention-strategies
#14
EDITORIAL
Joy Vink, Cynthia Gyamfi-Bannerman
No abstract text is available yet for this article.
November 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28495223/feasibility-of-text-message-influenza-vaccine-safety-monitoring-during-pregnancy
#15
Melissa S Stockwell, Maria Cano, Kathleen Jakob, Karen R Broder, Cynthia Gyamfi-Bannerman, Paula M Castaño, Paige Lewis, Angela Barrett, Oidda I Museru, Ormarys Castellanos, Philip S LaRussa
INTRODUCTION: The feasibility and accuracy of text messaging to monitor events after influenza vaccination throughout pregnancy and the neonatal period has not been studied, but may be important for seasonal and pandemic influenza vaccines and future maternal vaccines. METHODS: This prospective observational study was conducted during 2013-2014 and analyzed in 2015-2016. Enrolled pregnant women receiving inactivated influenza vaccination at a gestational age <20 weeks were sent text messages intermittently through participant-reported pregnancy end to request fever, health events, and neonatal outcomes...
May 2, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28295991/antenatal-corticosteroids-it-s-all-about-timing
#16
C Gyamfi-Bannerman
No abstract text is available yet for this article.
September 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28286050/the-role-of-maternal-age-in-twin-pregnancy-outcomes
#17
Amelia S McLennan, Cynthia Gyamfi-Bannerman, Cande V Ananth, Jason D Wright, Zainab Siddiq, Mary E D'Alton, Alexander M Friedman
BACKGROUND: There are limited data on how maternal age is related to twin pregnancy outcomes. OBJECTIVE: The purpose of this study was to assess the relationship between maternal age and risk for preterm birth, fetal death, and neonatal death in the setting of twin pregnancy. STUDY DESIGN: This population-based study of US birth, fetal death, and period-linked birth-infant death files from 2007-2013 evaluated neonatal outcomes for twin pregnancies...
July 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28142153/outcomes-of-operative-vaginal-delivery-during-trial-of-labor-after-cesarean-delivery
#18
Clifton O Brock, Shravya Govindappagari, Cynthia Gyamfi-Bannerman
Objective The objective of this study is to determine the maternal and neonatal morbidity associated with attempting operative vaginal delivery (OVD) compared with the alternative of a laboring repeat cesarean delivery (LRCD) in women attempting a trial of labor after cesarean delivery (TOLAC). Methods This is a secondary analysis of a multicenter prospective study designed to assess perinatal outcomes of OVD in women with a prior uterine scar. The study includes women who attempted TOLAC and reached +2 station with a fully dilated cervix...
July 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/27729253/association-between-change-in-cervical-length-and-spontaneous-preterm-birth-in-twin-pregnancies
#19
Leslie A Moroz, Clifton O Brock, Shravya Govindappagari, Denise L Johnson, Beth H Leopold, Cynthia Gyamfi-Bannerman
BACKGROUND: There is a lack of consensus on the optimal transvaginal cervical length for determining risk for spontaneous preterm birth in twin pregnancies. Change in transvaginal cervical length over time may reflect early activation of the parturition process, as has been demonstrated in singleton pregnancies. The association between change in transvaginal cervical length and the risk for spontaneous preterm birth has not yet been described in the population of women with diamniotic twin pregnancies...
February 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27500933/comparison-of-respiratory-outcomes-between-preterm-small-for-gestational-age-and-appropriate-for-gestational-age-infants
#20
MULTICENTER STUDY
Amy L Turitz, Cynthia Gyamfi-Bannerman
Objective  This study aims to determine whether preterm infants who are small for gestational age (SGA) are more likely to have respiratory distress syndrome (RDS) compared with appropriate-for-gestational-age infants. Methods  Secondary analysis of a multicenter trial evaluating magnesium for neuroprotection. Nonanomalous, singleton gestations delivered between 22 0/7 and 36 6/7 weeks were included. Large-for-gestational-age infants were excluded. We performed a nested case-control study. Cases were infants with RDS; controls were infants without RDS...
February 2017: American Journal of Perinatology
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