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Uma Reddy

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https://www.readbyqxmd.com/read/27830971/psychometric-properties-of-stress-and-anxiety-measures-among-nulliparous-women
#1
Carla M Bann, Corette B Parker, William A Grobman, Marian Willinger, Hyagriv N Simhan, Deborah A Wing, David M Haas, Robert M Silver, Samuel Parry, George R Saade, Ronald J Wapner, Michal A Elovitz, Emily S Miller, Uma M Reddy
OBJECTIVE: To examine the psychometric properties of three measures, the perceived stress scale (PSS), pregnancy experience scale (PES), and state trait anxiety inventory (STAI), for assessing stress and anxiety during pregnancy among a large sample of nulliparous women. METHODS: The sample included 10,002 pregnant women participating in the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (nMoM2b). Internal consistency reliability was assessed with Cronbach's alpha and factorial validity with confirmatory factor analyses...
November 10, 2016: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27824768/relationship-between-excessive-gestational-weight-gain-and-neonatal-adiposity-in-women-with-mild-gestational-diabetes-mellitus
#2
Sean C Blackwell, Mark B Landon, Lisa Mele, Uma M Reddy, Brian M Casey, Ronald J Wapner, Michael W Varner, Dwight J Rouse, John M Thorp, Anthony Sciscione, Patrick Catalano, George Saade, Steve N Caritis, Yoram Sorokin, William A Grobman
OBJECTIVE: To evaluate the relationships among excessive gestational weight gain, neonatal adiposity, and adverse obstetric outcomes in women with mild gestational diabetes mellitus. METHODS: This is a secondary analysis of a multicenter randomized clinical trial of women with mild gestational diabetes mellitus. Based on self-reported prepregnancy body weight, gestational weight gain was categorized as excessive if it was greater than 2009 Institute of Medicine guidelines...
December 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27776061/in-reply
#3
Tetsuya Kawakita, Katherine L Grantz, Uma M Reddy, Anthony C Sciscione
No abstract text is available yet for this article.
November 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27741203/maternal-and-neonatal-outcomes-with-early-compared-with-delayed-pushing-among-nulliparous-women
#4
Lynn M Yee, Grecio Sandoval, Jennifer Bailit, Uma M Reddy, Ronald J Wapner, Michael W Varner, Steve N Caritis, Mona Prasad, Alan T N Tita, George Saade, Yoram Sorokin, Dwight J Rouse, Sean C Blackwell, Jorge E Tolosa
OBJECTIVE: To describe factors associated with delayed pushing and evaluate the relationship between delayed pushing and perinatal outcomes in nulliparous women with singleton term gestations. METHODS: This was a secondary analysis of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Assessment of Perinatal Excellence cohort of 115,502 women and their neonates born in 25 U.S. hospitals from 2008 to 2011. Nulliparous women with singleton, cephalic, nonanomalous term births who achieved 10-cm cervical dilation were included...
November 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27728662/a-rare-case-of-wilsons-disease-carrier-with-mixed-connective-tissue-disorder
#5
P Lakshmi Raghavendra, Uma Ma, Srinivasa Rao, Yjv Reddy
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728521/diaphragmatic-flutter-leeuwenhoek-s-disease-belly-dancers-syndrome-in-a-case-of-metabolic-encephalopathy
#6
B G Rohit, Srinivasa Rao, Uma, Harish, Yjv Reddy
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27630644/over-expression-of-topoisomerase-ii-enhances-salt-stress-tolerance-in-tobacco
#7
Riffat John, Uma Ganeshan, Badri N Singh, Tanushri Kaul, Malireddy K Reddy, Sudhir K Sopory, Manchikatla V Rajam
Topoisomerases are unique enzymes having an ability to remove or add DNA supercoils and untangle the snarled DNA. They can cut, shuffle, and religate DNA strands and remove the torsional stress during DNA replication, transcription or recombination events. In the present study, we over-expressed topoisomerase II (TopoII) in tobacco (Nicotiana tabaccum) and examined its role in growth and development as well as salt (NaCl) stress tolerance. Several putative transgenic plants were generated and the transgene integration and expression was confirmed by PCR and Southern blot analyses, and RT-PCR analysis respectively...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27500932/racial-ethnic-disparities-in-measures-of-self-reported-psychosocial-states-and-traits-during-pregnancy
#8
William A Grobman, Corette Parker, Pathik D Wadhwa, Marian Willinger, Hyagriv Simhan, Bob Silver, Ron J Wapner, Samuel Parry, Brian Mercer, David Haas, Alan M Peaceman, Shannon Hunter, Deborah Wing, Steve Caritis, Sean Esplin, Matt Hoffman, Jack Ludmir, Jay Iams, Emily Long, George Saade, Uma M Reddy
Background The aim of this study was to determine whether racial/ethnic differences in psychosocial measures, independent of economic status, exist among a large population of pregnant nulliparas. Methods Between October 2010 and September 2013, nulliparous women at eight U.S. medical centers were followed longitudinally during pregnancy and completed validated instruments to quantify several psychosocial domains: Cohen Perceived Stress Scale, trait subscale of the Spielberger Anxiety Inventory, Connor-Davidson Resilience Scale, Multidimensional Scale of Perceived Social Support, Krieger Racism Scale, Edinburgh Postnatal Depression Scale, and the Pregnancy Experience Scale...
December 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27500344/association-of-recorded-estimated-fetal-weight-and-cesarean-delivery-in-attempted-vaginal-delivery-at-term
#9
Rosemary J Froehlich, Grecio Sandoval, Jennifer L Bailit, William A Grobman, Uma M Reddy, Ronald J Wapner, Michael W Varner, John M Thorp, Mona Prasad, Alan T N Tita, George Saade, Yoram Sorokin, Sean C Blackwell, Jorge E Tolosa
OBJECTIVE: To evaluate the association between documentation of estimated fetal weight, and its value, with cesarean delivery. METHODS: This was a secondary analysis of a multicenter observational cohort of 115,502 deliveries from 2008 to 2011. Data were abstracted by trained and certified study personnel. We included women at 37 weeks of gestation or greater attempting vaginal delivery with live, nonanomalous, singleton, vertex fetuses and no history of cesarean delivery...
September 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27400012/duration-of-oxytocin-and-rupture-of-the-membranes-before-diagnosing-a-failed-induction-of-labor
#10
Tetsuya Kawakita, Uma M Reddy, Sara N Iqbal, Helain J Landy, Chun-Chih Huang, Matthew Hoffman, Anthony C Sciscione, Katherine L Grantz
OBJECTIVE: To compare maternal and neonatal outcomes based on length of the latent phase during induction with rupture of membranes before 6 cm dilation. METHODS: This is a retrospective cohort study using data from the Consortium of Safe Labor study, including 9,763 nulliparous and 8,379 multiparous women with singleton, term pregnancies undergoing induction at 2 cm dilation or less with rupture of membranes before 6 cm dilation after which the latent phase ended...
August 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27398706/cell-free-total-and-fetal-dna-in-first-trimester-maternal-serum-and-subsequent-development-of-preeclampsia
#11
Robert M Silver, Leslie Myatt, John C Hauth, Kenneth J Leveno, Alan M Peaceman, Susan M Ramin, Philip Samuels, George Saade, Yoram Sorokin, Rebecca G Clifton, Uma M Reddy
Objective The objective of this study was to assess the relationship between first trimester cell-free total and fetal DNA in maternal plasma and the subsequent development of preeclampsia. Study Design Nested case-control study of patients enrolled in the Combined Antioxidant and Preeclampsia Prediction Studies prediction study of 175 women who did and 175 women who did not develop preeclampsia. The predictive values of cell-free total and fetal DNA and the subsequent development of preeclampsia were measured using receiver operating characteristic curves...
July 11, 2016: American Journal of Perinatology
https://www.readbyqxmd.com/read/27377502/association-of-cdkal1-cdkn2a-b-hhex-gene-polymorphisms-with-type-2-diabetes-mellitus-in-the-population-of-hyderabad-india
#12
Uma Jyothi Kommoju, Subburaj Kadarkarai Samy, Jayaraj Maruda, Kumuda Irgam, Jaya Prasad Kotla, Lakshmi Velaga, Battini Mohan Reddy
BACKGROUND & OBJECTIVES: The genome-wide association studies (GWAS) have shown an association of type 2 diabetes mellitus (T2DM) with several novel genes. We report here the findings on the pattern of genetic association of three genes (CDKAL1, CDKN2A/B and HHEX) with T2DM in the population of Hyderabad, south India. METHODS: A sample of 1379 individuals (758 T2DM cases and 621 controls) from Hyderabad, India, were genotyped for five single nucleotide polymorphisms (SNPs) of CDKAL1 (rs7754840, rs7756992) CDKN2A/B (rs10811661) and HHEX (rs1111875, rs7923837) genes on Sequenom Mass Array platform...
April 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27344190/what-we-have-learned-about-the-design-of-randomized-trials-in-pregnancy
#13
REVIEW
Elizabeth A Thom, Madeline Murguia Rice, George R Saade, Uma M Reddy
For nearly 30 years the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network has been conducting randomized trials in pregnant women, many of which have changed clinical practice. Since 1986, the MFMU Network has conducted 29 randomized trials, of which the 17 trials started or completed since 2003 are described here. Study design choices are described including decisions regarding the fundamental questions to be answered and the rationale behind choices of primary and secondary outcomes...
August 2016: Seminars in Perinatology
https://www.readbyqxmd.com/read/27333970/randomized-trial-of-a-dual-hormone-artificial-pancreas-with-dosing-adjustment-during-exercise-compared-with-no-adjustment-and-sensor-augmented-pump-therapy
#14
P G Jacobs, J El Youssef, R Reddy, N Resalat, D Branigan, J Condon, N Preiser, K Ramsey, M Jones, C Edwards, K Kuehl, J Leitschuh, U Rajhbeharrysingh, J R Castle
AIMS: To test whether adjusting insulin and glucagon in response to exercise within a dual-hormone artificial pancreas (AP) reduces exercise-related hypoglycaemia. MATERIALS AND METHODS: In random order, 21 adults with type 1 diabetes (T1D) underwent three 22-hour experimental sessions: AP with exercise dosing adjustment (APX); AP with no exercise dosing adjustment (APN); and sensor-augmented pump (SAP) therapy. After an overnight stay and 2 hours after breakfast, participants exercised for 45 minutes at 60% of their maximum heart rate, with no snack given before exercise...
November 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27324101/stillbirth-hypertensive-disorders-of-pregnancy-and-placental-pathology
#15
Karen J Gibbins, Robert M Silver, Halit Pinar, Uma M Reddy, Corette B Parker, Vanessa Thorsten, Marian Willinger, Donald J Dudley, Radek Bukowski, George R Saade, Matthew A Koch, Deborah Conway, Carol J Hogue, Barbara J Stoll, Robert L Goldenberg
INTRODUCTION: Stillbirth, preeclampsia, and gestational hypertension (PE/GH) have similar clinical risk factors and redundant placental pathology. We aim to discern if stillbirth with PE/GH has a particular phenotype by comparing stillbirths with and without PE/GH. METHODS: Secondary analysis of the Stillbirth Collaborative Research Network, a population-based cohort study of all stillbirths and a sample of live births from 2006 to 2008 in five catchment areas. We compared placental pathology between stillbirths and with and without PE/GH, stratified by term or preterm...
July 2016: Placenta
https://www.readbyqxmd.com/read/27275810/screening-prevention-and-treatment-of-opioid-use-disorder-during-pregnancy-expectant-mothers-are-depending-on-you
#16
Uma M Reddy
No abstract text is available yet for this article.
July 2016: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27210064/indications-for-primary-cesarean-delivery-relative-to-body%C3%A2-mass-index
#17
Tetsuya Kawakita, Uma M Reddy, Helain J Landy, Sara N Iqbal, Chun-Chih Huang, Katherine L Grantz
BACKGROUND: Obesity is a known risk factor for cesarean delivery. Limited data are available regarding the reasons for the increased rate of primary cesarean in obese women. It is important to identify the factors leading to an increased risk of cesarean to identify opportunities to reduce the primary cesarean rate. OBJECTIVE: We evaluated indications for primary cesarean across body mass index (kg/m(2)) classes to identify the factors contributing to the increased rate of cesarean among obese women...
October 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/27161434/introduction
#18
EDITORIAL
Uma M Reddy, George R Saade, Elizabeth A Thom
No abstract text is available yet for this article.
August 2016: Seminars in Perinatology
https://www.readbyqxmd.com/read/27151903/prediction-of-spontaneous-preterm-birth-among-nulliparous-women-with-a-short-cervix
#19
William A Grobman, Yinglei Lai, Jay D Iams, Uma M Reddy, Brian M Mercer, George Saade, Alan T Tita, Dwight J Rouse, Yoram Sorokin, Ronald J Wapner, Kenneth J Leveno, Sean C Blackwell, M Sean Esplin, Jorge E Tolosa, John M Thorp, Steve N Caritis
OBJECTIVES: The purpose of this study was to evaluate whether demographic and sonographic factors associated with spontaneous preterm birth among nulliparous women with a cervical length of less than 30 mm could be combined into an accurate prediction model for spontaneous preterm birth. METHODS: We conducted a secondary analysis of a trial of nulliparous women with a singleton gestation and a cervical length of less than 30 mm on transvaginal sonography between 16 and 22 weeks who lacked other risk factors for spontaneous (eg, prior cervical excisional procedure) or medically indicated (eg, chronic hypertension) preterm birth, who were randomized to either 17α-hydroxyprogesterone caproate treatment or a placebo...
June 2016: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/27131585/factor-v-leiden-prothrombin-g20210a-and-methylene-tetrahydrofolate-reductase-mutations-and-stillbirth-the-stillbirth-collaborative-research-network
#20
Robert M Silver, George R Saade, Vanessa Thorsten, Corette B Parker, Uma M Reddy, Carey Drews-Botsch, Deborah Conway, Donald Coustan, Donald J Dudley, Radek Bukowski, Carol J Rowland Hogue, Halit Pinar, Michael W Varner, Robert Goldenberg, Marian Willinger
BACKGROUND: An evaluation for heritable thrombophilias is recommended in the evaluation of stillbirth. However, the association between thrombophilias and stillbirth remains uncertain. OBJECTIVE: We sought to assess the association between maternal and fetal/placental heritable thrombophilias and stillbirth in a population-based, case-control study in a geographically, racially, and ethnically diverse population. STUDY DESIGN: We conducted secondary analysis of data from the Stillbirth Collaborative Research Network, a population-based case-control study of stillbirth...
October 2016: American Journal of Obstetrics and Gynecology
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