Dario Tino Bertolone, Pasquale Paolisso, Emanuele Gallinoro, Marta Belmonte, Konstantinos Bermpeis, Cristina De Colle, Giuseppe Esposito, Serena Caglioni, Davide Fabbricatore, Chiara Valeriano, Monika Shumkova, Tatyana Storozhenko, Michele Mattia Viscusi, Giulia Botti, Sofie Verstreken, Carmine Morisco, Emanuele Barbato, Jozef Bartunek, Marc Vanderheyden
Acute decompensated heart failure (ADHF) is a major cause of hospitalizations in older adults, leading to high mortality, morbidity, and healthcare costs. To address the persistent poor outcomes in ADHF, novel device-based approaches targeting specific pathophysiological mechanisms are urgently needed. The recently introduced DRI2 P2 S classification categorizes these innovative therapies based on their mechanisms. Devices include dilators (increasing venous capacitance), removers (directly removing sodium and water), inotropes (enhancing left ventricular contractility), interstitials (accelerating lymph removal), pushers (increasing renal arterial pressure), pullers (decreasing renal venous pressure), and selective drippers (selective intrarenal drug infusion)...
August 6, 2023: Current Problems in Cardiology