Jesus Alvarez-Garcia, Anuradha Lala, Mercedes Rivas-Lasarte, Clemencia De Rueda, Danielle Brunjes, Sara Lozano-Jimenez, Cristina Garcia-Sebastian, Sumeet Mitter, Paloma Remior, Marta Jimenez-Blanco Bravo, Susana Del Prado, Maya Barghash, Eduardo González-Ferrer, Jennifer Ullman, Marta Cobo, Javier Segovia-Cubero, José Luis Zamorano, Sean P Pinney, Donna Mancini
BACKGROUND: Incomplete treatment of congestion often leads to worsening heart failure (HF). The remote dielectric sensing (ReDS) system is an electromagnetic energy-based technology that accurately quantifies changes in lung fluid concentration noninvasively. OBJECTIVES: This study sought to assess whether an ReDS-guided strategy during acutely decompensated HF hospitalization is superior to routine care for improving outcomes at 1 month postdischarge. METHODS: ReDS-SAFE HF (Use of ReDS for a SAFE discharge in patients with acute Heart Failure) was an investigator-initiated, multicenter, single-blind, randomized, proof-of-concept trial in which 100 patients were randomized to a routine care strategy, with discharge criteria based on current clinical practice, or an ReDS-guided decongestion strategy, with discharge criteria requiring an ReDS value of ≤35%...
February 12, 2024: JACC. Heart Failure