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https://www.readbyqxmd.com/read/28746660/somatic-maturation-and-the-relationship-between-bone-mineral-variables-and-types-of-sports-among-adolescents-cross-sectional-study
#1
Ricardo Ribeiro Agostinete, Igor Hideki Ito, Han Kemper, Carlos Marcelo Pastre, Mário Antônio Rodrigues-Júnior, Rafael Luiz-de-Marco, Rômulo Araújo Fernandes
CONTEXT AND OBJECTIVE: Peak height velocity (PHV) is an important maturational event during adolescence that affects skeleton size. The objective here was to compare bone variables in adolescents who practiced different types of sports, and to identify whether differences in bone variables attributed to sports practice were dependent on somatic maturation status. DESIGN AND SETTING: Cross-sectional study, São Paulo State University (UNESP). METHODS: The study was composed of 93 adolescents (12 to 16...
May 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28744683/sources-and-toxicities-of-phenolic-polychlorinated-biphenyls-oh-pcbs
#2
Kiran Dhakal, Gopi S Gadupudi, Hans-Joachim Lehmler, Gabriele Ludewig, Michael W Duffel, Larry W Robertson
Polychlorinated biphenyls (PCBs), a group of 209 congeners that differ in the number and position of chlorines on the biphenyl ring, are anthropogenic chemicals that belong to the persistent organic pollutants (POPs). For many years, PCBs have been a topic of interest because of their biomagnification in the food chain and their environmental persistence. PCBs with fewer chlorine atoms, however, are less persistent and more susceptible to metabolic attack, giving rise to chemicals characterized by the addition of one or more hydroxyl groups to the chlorinated biphenyl skeleton, collectively known as hydroxylated PCBs (OH-PCBs)...
July 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28744680/the-effect-of-corn-distiller-s-dried-grains-with-solubles-ddgs-fortified-with-enzyme-on-growth-performance-of-broiler
#3
Alaeldein Mahmood Abudabos, Raed Muhammad Al-Atiyat, Dragons Stanley, Rafat Aljassim, Hamad Ali Albatshan
The objective of the current study was to investigate the effect of corn distiller's dried grains with solubles (DDGS) and enzyme supplementation on growth performance and carcass yield in broiler chickens. The experiment was a 5 × 3 factorial design with 450 broiler chickens and with diets containing five levels of DDGS (0, 6, 12, 18, and 24%) and three levels of the enzymes (no supplementation, Rovabio® enzyme, and Tomoko® enzyme). Five pens with six chicks were fed an experimental diet from 0 to 35 days of age...
July 25, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28744217/the-association-of-combined-gstm1-and-cyp2c9-genotype-status-with-the-occurrence-of-hemorrhagic-cystitis-in-pediatric-patients-receiving-myeloablative-conditioning-regimen-prior-to-allogeneic-hematopoietic-stem-cell-transplantation
#4
Chakradhara Rao S Uppugunduri, Flavia Storelli, Vid Mlakar, Patricia Huezo-Diaz Curtis, Aziz Rezgui, Yves Théorêt, Denis Marino, Fabienne Doffey-Lazeyras, Yves Chalandon, Peter Bader, Youssef Daali, Henrique Bittencourt, Maja Krajinovic, Marc Ansari
Hemorrhagic cystitis (HC) is one of the complications of busulfan-cyclophosphamide (BU-CY) conditioning regimen during allogeneic hematopoietic stem cell transplantation (HSCT) in children. Identifying children at high risk of developing HC in a HSCT setting could facilitate the evaluation and implementation of effective prophylactic measures. In this retrospective analysis genotyping of selected candidate gene variants was performed in 72 children and plasma Sulfolane (Su, water soluble metabolite of BU) levels were measured in 39 children following treatment with BU-CY regimen...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28736692/evaluating-the-impact-of-a-hiv-low-risk-express-care-task-shifting-program-a-case-study-of-the-targeted-learning-roadmap
#5
Linh Tran, Constantin T Yiannoutsos, Beverly S Musick, Kara K Wools-Kaloustian, Abraham Siika, Sylvester Kimaiyo, Mark J van der Laan, Maya Petersen
In conducting studies on an exposure of interest, a systematic roadmap should be applied for translating causal questions into statistical analyses and interpreting the results. In this paper we describe an application of one such roadmap applied to estimating the joint effect of both time to availability of a nurse-based triage system (low risk express care (LREC)) and individual enrollment in the program among HIV patients in East Africa. Our study population is comprised of 16,513 subjects found eligible for this task-shifting program within 15 clinics in Kenya between 2006 and 2009, with each clinic starting the LREC program between 2007 and 2008...
December 2016: Epidemiologic Methods
https://www.readbyqxmd.com/read/28736377/-association-of-ras-mutations-in-circulating-cell-free-dna-in-the-plasma-with-clinicopathological-features-of-colorectal-cancer
#6
Jing Wu, Li-Rong Zhao, Xiu-Qiang Lin, Fen Feng, Yong-Chang Chen, Wei-Ying Deng, Yan-Ming Deng, Wei Wang
OBJECTIVE: To detect RAS mutations in the circulating cell-free DNA (cfDNA) in the plasma and explore the their correlation with the clinicopathological features in patients with colorectal cancer. METHODS: Real-time PCR was used to detect RAS mutations in plasma cfDNA and matched tumor tissue DNA samples from 71 colorectal cancer patients. The correlation of RAS mutations with the clinicopathological features of the patients were analyzed. RESULTS: Of the 71 patients with colorectal cancer, 23 (32...
July 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28732592/correlation-between-early-revascularization-and-major-cardiac-events-demonstrated-by-ischemic-myocardium-in-japanese-patients-with-stable-coronary-artery-disease
#7
Shunichi Yoda, Yusuke Hori, Misa Hayase, Takashi Mineki, Takumi Hatta, Yasuyuki Suzuki, Naoya Matsumoto, Atsushi Hirayama
BACKGROUND: There is no report on correlation between early revascularization and the occurrence of major cardiac events (MCEs) except severe heart failure in Japanese patients with stable coronary artery disease (CAD). This study aimed to determine whether early revascularization affected the incidence of MCEs in Japanese patients with stable CAD. METHODS: We retrospectively investigated 3581 stable CAD patients who underwent rest (201)Tl and stress (99m)Tc-tetrofosmin myocardial perfusion single-photon emission computed tomography (SPECT) and provided three-year-prognostic data...
July 18, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28731686/pyrethroid-insecticide-cypermethrin-accelerates-pubertal-onset-in-male-mice-via-disrupting-hypothalamic-pituitary-gonadal-axis
#8
Xiaoqing Ye, Feixue Li, Jianyun Zhang, Huihui Ma, Dapeng Ji, Xin Huang, Thomas E Curry, Weiping Liu, Jing Liu
Pyrethroids, a class of insecticides that are widely used worldwide, have been identified as endocrine-disrupting chemicals (EDCs). Our recent epidemiological study reported on an association of increased pyrethroids exposure with elevated gonadotropins levels and earlier pubertal development in Chinese boys. In this study, we further investigated the effects of cypermethrin (CP), one of the most ubiquitous pyrethroid insecticides, on hypothalamic-pituitary-gonadal (HPG) axis and pubertal onset in male animal models...
July 21, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28723973/hypoalbuminemia-at-admission-predicts-the-development-of-acute-kidney-injury-in-hospitalized-patients-a-retrospective-cohort-study
#9
Mi-Yeon Yu, Sung Woo Lee, Seon Ha Baek, Ki Young Na, Dong-Wan Chae, Ho Jun Chin, Sejoong Kim
BACKGROUND: Development of acute kidney injury (AKI) is common and is associated with poor outcomes. We aimed to determine whether hypoalbuminemia (HA) at admission could be a risk factor for the development of AKI and mortality in hospitalized patients. METHODS: We enrolled patients who were admitted to Seoul National University Bundang Hospital from January 2013 to December 2013. HA at admission was defined as a serum albumin level < 3.4 mg/dL measured within two days after admission...
2017: PloS One
https://www.readbyqxmd.com/read/28723632/potential-link-between-fusobacterium-enrichment-and-dna-methylation-accumulation-in-the-inflammatory-colonic-mucosa-in-ulcerative-colitis
#10
Tomomitsu Tahara, Ichiro Hirata, Naoko Nakano, Sayumi Tahara, Noriyuki Horiguchi, Tomohiko Kawamura, Masaaki Okubo, Takamitsu Ishizuka, Hyuga Yamada, Dai Yoshida, Takafumi Ohmori, Kohei Maeda, Naruomi Komura, Hirokazu Ikuno, Yasutaka Jodai, Toshiaki Kamano, Mitsuo Nagasaka, Yoshihito Nakagawa, Tetsuya Tuskamoto, Makoto Urano, Tomoyuki Shibata, Makoto Kuroda, Naoki Ohmiya
BACKGROUND AND AIM: Fusobacterium enrichment has been associated with colorectal cancer development. Ulcerative colitis (UC) associated tumorigenesis is characterized as high degree of methylation accumulation through continuous colonic inflammation. The aim of this study was to investigate a potential link between Fusobacterium enrichment and DNA methylation accumulation in the inflammatory colonic mucosa in UC. METHODS: In the candidate analysis, inflamed colonic mucosa from 86 UC patients were characterized the methylation status of colorectal a panel of cancer related 24 genes...
June 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/28722009/highly-variable-recurrence-of-tsunamis-in-the-7-400-years-before-the-2004-indian-ocean-tsunami
#11
Charles M Rubin, Benjamin P Horton, Kerry Sieh, Jessica E Pilarczyk, Patrick Daly, Nazli Ismail, Andrew C Parnell
The devastating 2004 Indian Ocean tsunami caught millions of coastal residents and the scientific community off-guard. Subsequent research in the Indian Ocean basin has identified prehistoric tsunamis, but the timing and recurrence intervals of such events are uncertain. Here we present an extraordinary 7,400 year stratigraphic sequence of prehistoric tsunami deposits from a coastal cave in Aceh, Indonesia. This record demonstrates that at least 11 prehistoric tsunamis struck the Aceh coast between 7,400 and 2,900 years ago...
July 19, 2017: Nature Communications
https://www.readbyqxmd.com/read/28720265/the-mediating-role-of-resilience-in-the-relationship-between-social-support-and-posttraumatic-growth-among-colorectal-cancer-survivors-with-permanent-intestinal-ostomies-a-structural-equation-model-analysis
#12
Xiaoling Dong, Guopeng Li, Chunlei Liu, Linghua Kong, Yueyan Fang, Xiaofei Kang, Ping Li
PURPOSE: Information on posttraumatic growth (PTG) among colorectal cancer (CRC) survivors with permanent intestinal ostomies is limited. The aim of this cross-sectional study was to investigate the occurrence of PTG among CRC survivors with permanent intestinal ostomies and its association with perceived social support and resilience. METHODS: This study was conducted with 164 CRC survivors with permanent intestinal ostomies at least one month after surgery. Participants completed questionnaires assessing socio-demographic and clinical characteristics, perceived social support, resilience and PTG...
August 2017: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
https://www.readbyqxmd.com/read/28719618/an-update-on-psoriasis-and-metabolic-syndrome-a-meta-analysis-of-observational-studies
#13
Sanminder Singh, Paulina Young, April W Armstrong
The relationship between psoriasis and metabolic syndrome is not well understood. Though multiple epidemiologic studies have suggested a link between psoriasis and metabolic syndrome, there is a lack of a comprehensive meta-analysis synthesizing the results of all available observational studies to date. In this meta-analysis, we examined global data on the relationship between psoriasis and odds of metabolic syndrome by searching for studies published between 1946-2016. Specifically, we analyzed the results from 35 observational studies from 20 countries with 1,450,188 total participants, of which 46,714 were psoriasis patients...
2017: PloS One
https://www.readbyqxmd.com/read/28719361/effectiveness-of-valganciclovir-900mg-versus-450mg-for-cytomegalovirus-prophylaxis-in-renal-transplantation-a-systematic-review-and-meta-analysis
#14
Wang Xin, Yang Hui, Zhang Xiaodong, Cui Xiangli, Wang Shihui, Liu Lihong
OBJECTIVES: Valganciclovir 900 mg/day is approved for cytomegalovirus (CMV) prophylaxis, but 450 mg/day is seems also effective. We systematically reviewed the efficacy and safety of low-dose versus high-dose valganciclovir prophylaxis in renal transplantation recipients. METHODS: An electronic search was conducted up to November 29, 2016. The primary outcomes were incidences of CMV, CMV disease, mortality and opportunistic infection. The second outcomes were acute rejection, allograft loss, adverse drug reaction (ADR)...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28718668/olea-europaea-leaf-extract-improves-the-efficacy-of-temozolomide-therapy-by-inducing-mgmt-methylation-and-reducing-p53-expression-un-glioblastoma
#15
Gulcin Tezcan, Berrin Tunca, Hilal Demirci, Ahmet Bekar, Mevlut Ozgur Taskapilioglu, Hasan Kocaeli, Unal Egeli, Gulsah Cecener, Sahsine Tolunay, Ozgur Vatan
Unmethylated O6-methylguanine-DNA-methyltransferase (MGMT) promoter leads to Temozolomide (TMZ) resistance in most of the glioblastoma multiforme (GBM) patients. We previously investigated the synergistic effect of Olea europaea leaf extract (OLE) on TMZ cytotoxicity through modulating microRNA expression. To date, knowledge about the effect of OLE on MGMT methylation is insufficient. The aim of the current study was to evaluate the potential modulating effect of OLE on the TMZ response of GBM tumors through MGMT methylation...
July 18, 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28717650/removal-of-cu-zn-pb-and-cr-from-yangtze-estuary-using-the-phragmites-australis-artificial-floating-wetlands
#16
Xiaofeng Huang, Feng Zhao, Gao Yu, Chao Song, Zhi Geng, Ping Zhuang
Contamination of heavy metals would threaten the water and soil resources; phytoremediation can be potentially used to remediate metal contaminated sites. We constructed the Phragmites australis artificial floating wetlands outside the Qingcaosha Reservoir in the Yangtze Estuary. Water characteristic variables were measured in situ by using YSI Professional Pro Meter. Four heavy metals (copper, zinc, lead, and chromium) in both water and plant tissues were determined. Four heavy metals in estuary water were as follows: 0...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28712152/teeth-bleaching-with-low-concentrations-of-hydrogen-peroxide-6-and-catalyzed-by-led-blue-450%C3%A2-%C3%A2-%C3%A2-10-nm-and-laser-infrared-808%C3%A2-%C3%A2-%C3%A2-10-nm-light-for-in-office-treatment-randomized-clinical-trial-1-year-follow-up
#17
Patricio Vildósola, Jessica Bottner, Francisca Avalos, Isidora Godoy, Javier Martín, Eduardo Fernández
OBJECTIVES: The aim of this study was to evaluate color longevity after a year of in-office bleaching with gel (6% hydrogen peroxide HP, LED blue/laser infrared activation system) compared to a 35% control concentration in a split-mouth study model. MATERIALS AND METHODS: Thirty-one patients were initially treated. The bleaching procedure with 6% or 35% gel HP was performed randomly in the upper half arcade of each patient. The color was measured at baseline and at 1 week, 1 month, and 1 year using the spectrophotometer Vita Easyshade, Vita Bleached, and Vita classical Shade guide organized by value...
July 16, 2017: Journal of Esthetic and Restorative Dentistry
https://www.readbyqxmd.com/read/28708609/evaluation-of-nutrients-removal-no3-n-nh3-n-and-po4-p-with-chlorella-vulgaris-pseudomonas-putida-bacillus-cereus-and-a-consortium-of-these-microorganisms-in-the-treatment-of-wastewater-effluents
#18
Abril Gómez-Guzmán, Sergio Jiménez-Magaña, A Suggey Guerra-Rentería, César Gómez-Hermosillo, F Javier Parra-Rodríguez, Sergio Velázquez, Blanca Rosa Aguilar-Uscanga, Josue Solis-Pacheco, Orfil González-Reynoso
In this research removal of NH3-N, NO3-N and PO4-P nutrients from municipal wastewater was studied, using Chlorella vulgaris, Pseudomonas putida, Bacillus cereus and an artificial consortium of them. The objective is to analyze the performance of these microorganisms and their consortium, which has not been previously studied for nutrient removal in municipal wastewater. A model wastewater was prepared simulating the physicochemical characteristics found at the wastewater plant in Chapala, Mexico. Experiments were carried out without adding an external carbon source...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28706141/epidermal-growth-factor-receptor-is-associated-with-the-onset-of-skeletal-related-events-in-non-small-cell-lung-cancer
#19
Shu-Mei Huang, Jin-Ji Yang, Hua-Jun Chen, Si-Pei Wu, Xiao-Yan Bai, Qing Zhou, Hai-Yan Tu, Yi-Long Wu
BACKGROUND: Bone metastasis and skeletal related events (SREs) are common in non-small cell lung cancer (NSCLC). Patients with mutant epidermal growth factor receptor (EGFR) could benefit from tyrosine kinase inhibitors (TKIs). However, it is unclear whether SRE is influenced by EGFR status. We aimed to evaluate the correlation of EGFR status and TKIs with the incidence of SREs. METHODS: We conducted a retrospective study of stage IV NSCLC patients with bone metastasis...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28705886/thyroid-status-quality-of-life-and-mental-health-in-patients-on-hemodialysis
#20
Connie M Rhee, Yanjun Chen, Amy S You, Steven M Brunelli, Csaba P Kovesdy, Matthew J Budoff, Gregory A Brent, Kamyar Kalantar-Zadeh, Danh V Nguyen
BACKGROUND AND OBJECTIVES: In the general population, there is increasing recognition of the effect of thyroid function on patient-centered outcomes, including health-related quality of life and depression. Although hypothyroidism is highly prevalent in hemodialysis patients, it is unknown whether thyroid status is a risk factor for impaired health-related quality of life or mental health in this population. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined the association of thyroid status, defined by serum thyrotropin, with health-related quality of life and depressive symptoms over time in a prospective cohort of 450 patients on hemodialysis from 17 outpatient dialysis facilities from May of 2013 to May of 2015 who underwent protocolized thyrotropin testing, Short-Form 36 surveys, and Beck Depression Inventory-II questionnaires every 6 months...
July 13, 2017: Clinical Journal of the American Society of Nephrology: CJASN
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