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https://www.readbyqxmd.com/read/27930554/pulsed-radiofrequency-treatment-of-the-superior-hypogastric-plexus-in-an-interstitial-cystitis-patient-with-chronic-pain-and-symptoms-refractory-to-oral-and-intravesical-medications-and-bladder-hydrodistension-a-case-report
#1
Jong Hae Kim, Eugene Kim, Bong Il Kim
RATIONALE: A variety of therapeutic modalities are available for the treatment of interstitial cystitis. However, among them, the less invasive therapies are usually ineffective, whereas the invasive ones carry potential risks of serious side effects and complications. Pulsed radiofrequency (PRF) treatment of the superior hypogastric plexus may be an alternative to conventional treatments, as it provides nondestructive neuromodulation to the superior hypogastric plexus, which transmits the majority of pain signals from the pelvic viscera...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27855473/-tobacco-use-and-utilization-of-medical-services-in-adolescence-an-analysis-of-the-kiggs-data
#2
A M Fassmer, A Luque Ramos, C Boiselle, S Dreger, S Helmer, H Zeeb
Objective: In Germany, there is a lack of information on the correlation between tobacco use by adolescents and their utilization of medical care. The aim of this article is to identify possible early consequences of adolescent smoking. Methods: We conducted a re-analysis of cross-sectional data of the baseline wave (2003-2006) of the German Health Survey for Children and Adolescents (KiGGS). To examine the association between current smoking status and utilization of medical care during the 12 months before the interview, prevalence of selected diseases was calculated, and stratified by smoking status...
November 17, 2016: Das Gesundheitswesen
https://www.readbyqxmd.com/read/27805245/active-schistosomiasis-severe-hypereosinophilia-and-rapid-progression-of-chronic-endomyocardial-fibrosis
#3
A O Mocumbi, C Goncalves, A Damasceno, C Carrilho
Endomyocardial fibrosis (EMF) is a neglected restrictive cardiomyopathy of unknown aetiology and unclear natural history, which causes premature deaths in endemic areas. We present the case of a 13-year-old boy from a highly endemic area, presenting with concurrent signs of chronic EMF and severe hypereosinophilia associated with active schistosomal cystitis. We discuss the possible role of this parasitic infection in determining the progression of EMF in endemic areas for both conditions.
October 23, 2016: Cardiovascular Journal of Africa
https://www.readbyqxmd.com/read/27795253/draft-genome-sequence-of-brazilian-escherichia-coli-uropathogenic-strain-e2
#4
Thiago G S Paim, Luiza Pieta, Janira Prichula, Gustavo E Sambrano, Renata Soares, Juliana Caierão, Jeverson Frazzon, Pedro A d'Azevedo
Escherichia coli is a common pathogen recovered from cystitis infections. In this report, we announce the draft genome sequence of strain E2 isolated from the urine specimen from a female patient in South Brazil. The genome assembly has 5,081,209 bp, a G+C content of 50.57%, and virulence factors associated with both enteroaggregative and uropathogenic E. coli strains.
October 6, 2016: Genome Announcements
https://www.readbyqxmd.com/read/27788495/evaluating-the-efficacy-and-safety-of-intravesical-chemotherapies-for-non-muscle-invasive-bladder-cancer-a-network-meta-analysis
#5
Chuanjun Zhuo, Xubin Li, Hongqing Zhuang, Shunli Tian, Hailong Cui, Ronghuan Jiang, Chuanxin Liu, Ran Tao, Xiaodong Lin
Various intravesical therapies have been introduced into clinical practices for controlling non-muscle invasive bladder cancer (NMIBC). However, evidence with respect to the efficacy and safety of those intravesical therapies is very limited. Hence, we present a network meta-analysis in order to address this limitation in the current literature. The primary outcomes were the risk of tumor recurrence (TR), tumor progression (TP) and disease-specific mortality (DM). Secondary outcomes included the risk of fever, cystitis and haematuria...
October 24, 2016: Oncotarget
https://www.readbyqxmd.com/read/27732661/molecular-basis-of-acute-cystitis-reveals-susceptibility-genes-and-immunotherapeutic-targets
#6
Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg
The clinical studies were approved by the Human Ethics Committee at Lund University (approval numbers LU106-02, LU236-99 and Clinical Trial Registration RTP-A2003, International Committee of Medical Journal Editors, www.clinicaltrials.gov).
October 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27694368/placement-of-subcutaneous-ureteral-bypasses-without-fluoroscopic-guidance-in-cats-with-ureteral-obstruction-19-cases-2014-2016
#7
Véronique Livet, Paul Pillard, Isabelle Goy-Thollot, David Maleca, Quentin Cabon, Denise Remy, Didier Fau, Éric Viguier, Céline Pouzot, Claude Carozzo, Thibaut Cachon
OBJECTIVES: The purpose of this study was to describe the perioperative and postoperative complications as well as short-term and long-term outcomes in cats with ureteral obstructions treated by placement of a subcutaneous ureteral bypass (SUB) device without imaging control. The second objective of this study was to compare cats treated by SUB device with cats treated by traditional surgical intervention. METHODS: Data were obtained retrospectively from the medical records (2014-2016) of cats that underwent SUB placement (SUB cats) and cats that underwent traditional ureteral surgery (C cats)...
September 30, 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27679168/treatment-of-bladder-pain-syndrome-and-interstitial-cystitis-a-systematic-review
#8
J C Rosa-E-Silva, C Pazin, Apm Silva, A M Mitidieri, M B Gurian
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27609597/in-vitro-susceptibility-to-mecillinam-of-escherichia-coli-strains-isolated-from-the-urine-of-pregnant-women
#9
C Duployez, C Loiez, C Cattoen, D Descamps, F Wallet, A Vachée
OBJECTIVES: Pivmecillinam is a safe beta-lactam for use in pregnancy. It has been widely used for the treatment of lower urinary tract infections (UTIs) in the Nordic countries where its efficacy, minor impact on the microbiota, and low level of resistance among the Escherichia coli strains have been proven. However, susceptibility data related to E. coli involved in asymptomatic bacteriuria and lower UTIs in pregnant women is lacking. We aimed to support the 2015 recommendations issued by the French Infectious Diseases Society (SPILF) on gestational UTI, with a particular focus on pivmecillinam...
December 2016: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/27595281/patterns-of-infection-and-infection-related-mortality-in-patients-with-steroid-refractory-acute-graft-versus-host-disease
#10
I García-Cadenas, I Rivera, R Martino, A Esquirol, P Barba, S Novelli, G Orti, J Briones, S Brunet, D Valcarcel, J Sierra
This study aimed to characterize the incidence, etiology and outcome of infectious episodes in patients with steroid refractory acute GvHD (SR-GvHD). The cohort included 127 adults treated with inolimomab (77%) or etanercept (23%) owing to acute 2-4 SR-GvHD, with a response rate of 43% on day +30 and a 4-year survival of 15%. The 1-year cumulative incidences of bacterial, CMV and invasive fungal infection were 74%, 65% and 14%, respectively. A high rate (37%) of enterococcal infections was observed. Twenty patients (15...
September 5, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27581769/important-role-of-physicians-in-addressing-psychological-aspects-of-interstitial-cystitis-bladder-pain-syndrome-ic-bps-a-qualitative-analysis
#11
Gregory Kanter, Katherine A Volpe, Gena C Dunivan, Sara B Cichowski, Peter C Jeppson, Rebecca G Rogers, Yuko M Komesu
INTRODUCTION: Interstitial cystitis/bladder pain syndrome (IC/BPS) is a poorly understood source of chronic pain causing significant morbidity, with variable treatment success. Despite the need to understand patient perspectives in chronic pain, there is a paucity of qualitative data for IC/BPS. We aimed to acquire information regarding patient experience with IC/BPS symptoms and with their medical care to elicit suggestions to improve patient satisfaction with that care. METHODS: Fifteen women with IC/PBS participated in a total of four focus groups...
August 31, 2016: International Urogynecology Journal
https://www.readbyqxmd.com/read/27489498/protective-effect-of-thymoquinone-against-cyclophosphamide-induced-hemorrhagic-cystitis-through-inhibiting-dna-damage-and-upregulation-of-nrf2-expression
#12
Prashant R Gore, Chaitali P Prajapati, Umesh B Mahajan, Sameer N Goyal, Sateesh Belemkar, Shreesh Ojha, Chandragouda R Patil
Cyclophosphamide (CYP) induced hemorrhagic cystitis is a dose-limiting side effect involving increased oxidative stress, inflammatory cytokines and suppressed activity of nuclear factor related erythroid 2-related factor (Nrf2). Thymoquinone (TQ), an active constituent of Nigella sativa seeds, is reported to increase the expression of Nrf2, exert antioxidant action, and anti-inflammatory effects in the experimental animals. The present study was designed to explore the effects of TQ on CYP-induced hemorrhagic cystitis in Balb/c mice...
2016: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/27431428/evaluation-of-urinary-bladder-fibrogenesis-in-a-mouse-model-of-long-term-ketamine-injection
#13
Cheng-Huang Shen, Shou-Chieh Wang, Shou-Tsung Wang, Shu-Mei Lin, Jiann-Der Wu, Chang-Te Lin, Yi-Wen Liu
Long-term ketamine abuse has been shown to affect the lower urinary tract and result in interstitial cystitis-like syndrome. However, the causative mechanism of ketamine-induced dysfunction remains unclear. The present study aimed to investigate the physiological, histological and molecular changes on ketamine‑associated cystitis (KC) in a mouse model. Both male and female Balb/c mice were separately distributed into the control group (normal saline) and ketamine group, which received ketamine hydrochloride (100 mg/kg/day) daily by intraperitoneal injection for a total period of 20 weeks...
September 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27427919/the-calcineurin-inhibitor-and-the-intensity-of-the-conditioning-regimen-may-affect-the-occurrence-of-polyomavirus-associated-hemorrhagic-cystitis-after-haploidentical-hematopoietic-stem-cell-transplantation-with-post-transplant-cyclophosphamide
#14
A Rimondo, R Crocchiolo, J El-Cheikh, S Bramanti, A Granata, S Furst, B Sarina, L Morabito, R Devillier, S Harbi, B Mohty, R Mineri, C Faucher, C Chabannon, A Santoro, D Blaise, L Castagna
No abstract text is available yet for this article.
July 18, 2016: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/27424995/d-mannose-a-promising-support-for-acute-urinary-tract-infections-in-women-a-pilot-study
#15
L Domenici, M Monti, C Bracchi, M Giorgini, V Colagiovanni, L Muzii, P Benedetti Panici
OBJECTIVE: Urinary tract infections still represent a significant bother for women and result in high costs to the health system. D-mannose is a simple sugar; it seems able to hinder bacteria adhesion to the urothelium. The present study aimed to determine whether D-mannose alone is effective in treating acute urinary tract infections in women and its possible utility in the management of recurrences. PATIENTS AND METHODS: This is a pilot study, performed between April 2014 and July 2015 at Department of Gynaecological Obstetrics and Urologic Sciences of "Sapienza" University of Rome...
July 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27383371/pathogenesis-of-streptococcus-urinary-tract-infection-depends-on-bacterial-strain-and-%C3%AE-hemolysin-cytolysin-that-mediates-cytotoxicity-cytokine-synthesis-inflammation-and-virulence
#16
Sophie Y Leclercq, Matthew J Sullivan, Deepak S Ipe, Joshua P Smith, Allan W Cripps, Glen C Ulett
Streptococcus agalactiae can cause urinary tract infection (UTI) including cystitis and asymptomatic bacteriuria (ABU). The early host-pathogen interactions that occur during S. agalactiae UTI and subsequent mechanisms of disease pathogenesis are poorly defined. Here, we define the early interactions between human bladder urothelial cells, monocyte-derived macrophages, and mouse bladder using uropathogenic S. agalactiae (UPSA) 807 and ABU-causing S. agalactiae (ABSA) 834 strains. UPSA 807 adhered, invaded and killed bladder urothelial cells more efficiently compared to ABSA 834 via mechanisms including low-level caspase-3 activation, and cytolysis, according to lactate dehydrogenase release measures and cell viability...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27362599/treatment-of-uncomplicated-cystitis-analysis-of-prescribing-in-new-zealand
#17
Natalie J Gauld, Irene Sl Zeng, Rosemary B Ikram, Mark G Thomas, Stephen A Buetow
AIMS: To describe prescribing for women with suspected urinary tract infections, including suspected uncomplicated cystitis, in New Zealand. METHODS: Randomly selected community pharmacies participated in the study. Women attending the pharmacy in a 2-week period in 2012 for prescribed or non-prescription treatment of symptoms suggesting a urinary tract infection, or prophylaxis of a urinary tract infection, were invited to self-complete a questionnaire. Analysis focused on prescribing for women with symptoms of cystitis without complicating features...
July 1, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27354295/protein-based-profiling-of-the-immune-response-to-uropathogenic-escherichia-coli-in-adult-patients-immediately-following-hospital-admission-for-acute-cystitis
#18
Lana Sundac, Samantha J Dando, Matthew J Sullivan, Petra Derrington, John Gerrard, Glen C Ulett
Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are common infections in humans. Despite the substantial healthcare cost represented by these infections, the human immune response associated with the infection immediately following the onset of symptoms in patients remains largely undefined. We performed a prospective study aimed at defining the milieu of urinary cytokines in adult inpatients in the 24-48 h period immediately following hospital admission for acute cystitis due to UPEC...
August 2016: Pathogens and Disease
https://www.readbyqxmd.com/read/27342943/-hyperbaric-oxygen-and-radiotherapy-from-myth-to-reality
#19
S Espenel, C Raffoux, A Vallard, M-A Garcia, J-B Guy, C Rancoule, M Ben Mrad, J Langrand-Escure, J-C Trone, G Pigne, P Diao, N Magné
Worldwide, more than a million people receive each year a curative radiotherapy. While local control and overall survival are steadily increasing, 5 to 15% of patients still develop above grade 2 late toxicities. Late toxicities treatments are complex. Hyperbaric oxygenation was shown to induce revascularization and healing of injured tissues, but indications are still debated. Through a literature review, we summarized the hyperbaric oxygenation indications in radiation-induced late toxicities. We also studied the knowledge and practice of French local radiation therapists...
July 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/27325475/time-course-and-accumulated-risk-of-severe-urinary-adverse-events-after-high-versus-low-dose-rate-prostate-brachytherapy-with-or%C3%A2-without-external-beam-radiation-therapy
#20
Jonathan D Tward, Stephanie Jarosek, Haitao Chu, Cameron Thorpe, Dennis C Shrieve, Sean Elliott
PURPOSE: Severe urinary adverse events (UAEs) include surgical treatment of urethral stricture, urinary incontinence, and radiation cystitis. We compared the incidence of grade 3 UAEs, according to the Common Terminology Criteria for Adverse Events, after low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy, as well as after LDR plus external beam radiation therapy (EBRT) and HDR plus EBRT. METHODS AND MATERIALS: Men aged >65 years with nonmetastatic prostate cancer were identified from the Surveillance, Epidemiology, and End Results-Medicare database who were treated with LDR (n=12,801), HDR (n=685), LDR plus EBRT (n=8518), or HDR plus EBRT (n=2392)...
August 1, 2016: International Journal of Radiation Oncology, Biology, Physics
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