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https://www.readbyqxmd.com/read/28533591/long-term-histopathological-developments-in-knee-joint-components-in-a-rat-model-of-osteoarthritis-induced-by-monosodium-iodoacetate
#1
Ikufumi Takahashi, Taro Matsuzaki, Masahiro Hoso
[Purpose] This study was performed to evaluate the long-term histopathological changes in knee-joint components including synovial membrane and joint capsule in a rat model of osteoarthritis (OA) induced by monosodium iodoacetate (MIA). [Subjects and Methods] Fifty male rats were used. OA was induced through intra-articular injection of MIA, and ten rats were randomly allocated to each of five groups induced with OA for 1, 2, 4, 6, or 8 weeks. At the end of each period, the knee components were examined histopathologically...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28532875/neck-pain-and-dysphagia-associated-to-disc-protrusion-and-reduced-functional-stability-a-case-report
#2
Michele Margelli, Carla Vanti, Jorge Hugo Villafañe, Roberto Andreotti
BACKGROUND: Deglutition dysfunction like dysphagia may be associated with cervical symptoms. FINDINGS: A young female complained of pain on the neck and swallowing dysfunction that was reduced by means of isometric contraction of cervical muscles. Magnetic resonance imaging revealed an anterior C5-C6 disc protrusion associated with a lesion of the anterior longitudinal ligament. Barium radiograph showed a small anterior cervical osteophyte at C6 level and dynamic X-ray excluded anatomical instability...
April 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28525486/regression-of-anterior-disk-osteophyte-complex-following-cervical-laminectomy-and-fusion-for-cervical-spondylotic-myelopathy
#3
Adedayo O Ashana, Jeremiah R Cohen, Brandon Evans, Langston T Holly
STUDY DESIGN: A retrospective case-control study. OBJECTIVE: To investigate whether posterior cervical laminectomy and fusion modifies the natural course of anterior disk-osteophyte complex in patients with multilevel cervical spondylotic myelopathy. SUMMARY OF BACKGROUND DATA: Dorsal migration of the spinal cord is the main purported mechanism of spinal cord decompression following cervical laminectomy and fusion but other potential mechanisms have received scant attention in the literature...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28509936/penetrating-osseous-spicules-causing-high-flow-ventral-csf-leaks-in-the-setting-of-relatively-low-bmi-a%C3%A2-preliminary-study
#4
Richard E Rosebrock, Felix E Diehn, Patrick H Luetmer, John T Wald, John I Lane, Jonathan M Morris, Vance T Lehman, Carrie M Carr, Bahram Mokri, Kent R Thielen
OBJECTIVE/BACKGROUND: We have anecdotally observed patients with high-flow ventral cerebrospinal fluid (CSF) leaks resulting from penetrating osseous spicules or calcified discs to be relatively thin. The purpose of this study was to explore the validity of this observation and determine if a potential association exists between low body mass index (BMI) and high-flow spinal ventral CSF leaks resulting from such dura-penetrating lesions. METHODS: Sixteen consecutive patients with precisely localized high-flow ventral spinal CSF leaks on dynamic myelography were identified...
May 16, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/28506227/associations-between-disc-space-narrowing-anterior-osteophytes-and-disability-in-chronic-mechanical-low-back-pain-a-cross-sectional-study
#5
Romain Shanil Perera, Poruwalage Harsha Dissanayake, Upul Senarath, Lalith Sirimevan Wijayaratne, Aranjan Lional Karunanayake, Vajira Harshadeva Weerabaddana Dissanayake
BACKGROUND: Radiographic features of lumbar disc degeneration (LDD) are common findings in patients with chronic mechanical low back pain; however, its role in disability and intensity of pain is debatable. This study aims to investigate the associations of the x-ray features of LDD and lumbar spondylolisthesis with severity of disability and intensity of pain. METHODS: A cross-sectional study was conducted on 439 patients with chronic mechanical low back pain who attended the rheumatology clinic, National Hospital of Sri Lanka, Colombo, from May 2012 to May 2014...
May 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28498070/extracranial-internal-carotid-artery-dissection-caused-by-compression-from-a-giant-osteophyte-due-to-atlantoaxial-osteoarthritis-case-report
#6
Taichi Ikedo, Kazuhito Nakamura, Noritaka Sano, Manabu Nagata, Yumiko Okada, Taichiro Kawakami, Takaho Murata
Deformed osseous structures have been reported as rare causes of extracranial internal carotid artery (ICA) dissection, including the styloid process and the hyoid bone. Here, the authors describe the first known case of symptomatic ICA dissection caused by a giant osteophyte due to atlantoaxial osteoarthritis. The left ICA was fixed at the skull base and at the ICA portion compressed by the osteophyte, and it was highly stretched and injured between the two portions during neck rotation. The patient was successfully treated with ligation of the affected ICA following balloon test occlusion...
May 12, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28488001/lateral-displacement-sulcus-angle-and-trochlear-angle-are-associated-with-early-patellofemoral-osteoarthritis-following-anterior-cruciate-ligament-reconstruction
#7
Erin M Macri, Adam G Culvenor, Hayden G Morris, Timothy S Whitehead, Trevor G Russell, Karim M Khan, Kay M Crossley
PURPOSE: Patellofemoral osteoarthritis (PFOA) occurs in approximately half of anterior cruciate ligament (ACL)-injured knees within 10-15 years of trauma. Risk factors for post-traumatic PFOA are poorly understood. Patellofemoral alignment and trochlear morphology may be associated with PFOA following ACL reconstruction (ACLR), and understanding these relationships, particularly early in the post-surgical time period, may guide effective early intervention strategies. In this study, patellofemoral alignment and trochlear morphology were investigated in relation to radiographic features of early PFOA 1-year post-ACLR...
May 9, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28472071/associations-between-mri-features-versus-knee-pain-severity-and-progression-data-from-the-vancouver-longitudinal-study-of-early-knee-osteoarthritis
#8
Eric C Sayre, Ali Guermazi, John M Esdaile, Jacek A Kopec, Joel Singer, Anona Thorne, Savvas Nicolaou, Jolanda Cibere
OBJECTIVE: To determine associations between features of osteoarthritis (OA) on MRI and knee pain severity and knee pain progression. DESIGN: Baseline, 3.3- and 7.5-year assessments were performed for 122 subjects with baseline knee pain (age 40-79), sample-weighted for population (with knee pain) representativeness. MRIs were scored for: osteophytes (0:absent to 3:large); cartilage (0:normal to 4:full thickness defect; 0/1 collapsed); subchondral sclerosis (0:none to 3:>50% of site), subchondral cyst (0:absent to 3:severe), bone marrow lesions (0:none to 3:≥50% of site); and meniscus (0:normal to 3:maceration/resection), in 6-8 regions each...
2017: PloS One
https://www.readbyqxmd.com/read/28471034/ultrasonography-detected-subclinical-inflammation-in-patients-with-hand-osteoarthritis-and-established-rheumatoid-arthritis-a-comparison-between-two-different-pathologies-using-the-same-ultrasound-examination-protocol
#9
Sidra Hussain, Priyanka Sivakumaran, Anna Gill, Delfin Dhas, Coziana Ciurtin
OBJECTIVES: A recent review of ultrasound (US) studies in osteoarthritis (OA) showed very limited data about hand OA. Previous US studies in patients with OA described a degree of overlap between the US appearance of rheumatoid arthritis (RA) and OA joints. The present study aimed to assess the US features of subclinical inflammation in RA and hand OA, using the same US examination protocol. METHODS: A retrospective, cohort study compared patients with established RA (n = 224) and hand OA (n = 73), with respect to several demographic, clinical, laboratory and US parameters...
May 4, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28462798/no-associations-between-self-reported-knee-joint-instability-and-radiographic-features-in-knee-osteoarthritis-patients-prior-to-total-knee-arthroplasty-a-cross-sectional-analysis-of-the-longitudinal-leiden-orthopaedics-outcomes-of-osteo-arthritis-study-loas
#10
Claudia S Leichtenberg, Jorit J L Meesters, Herman M Kroon, Suzan H M Verdegaal, Claire Tilbury, Joost Dekker, Rob G H H Nelissen, Thea P M Vliet Vlieland, Martin van der Esch
BACKGROUND: To describe the prevalence of self-reported knee joint instability in patients with pre-surgery knee osteoarthritis (OA) and to explore the associations between self-reported knee joint instability and radiological features. METHODS: A cross-sectional study including patients scheduled for primary Total Knee Arthroplasty (TKA). Self-reported knee instability was examined by questionnaire. Radiological features consisted of osteophyte formation and joint space narrowing (JSN), both scored on a 0 to three scale...
April 24, 2017: Knee
https://www.readbyqxmd.com/read/28456670/there-is-no-increased-risk-of-adjacent-segment-disease-at-the-cervico-thoracic-junction-following-an-anterior-cervical-discectomy-and-fusion-to-c7
#11
Philip K Louie, Steven M Presciutti, Stephanie E Iantorno, Daniel D Bohl, Kevin Shah, Grant D Shifflett, Howard S An
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a very common operative intervention for the treatment of cervical spine degenerative disease in those who have failed non-operative measures. However, studies examining long-term follow up on patients who underwent ACDF reveal evidence of radiographic and clinical degenerative disc disease at the levels adjacent to the fusion construct. Consistent with other junctional regions of the spine, the cervicothoracic junction (CTJ) has significant morphological variations...
April 26, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28442858/observer-variability-in-evaluating-pisotriquetral-osteoarthritis-using-pisotriquetral-view
#12
Erik Heeg, Paul W L Ten Berg, Mario Maas, Simon D Strackee
A pisotriquetral (semilateral) view of the wrist may improve the assessment of pisotriquetral osteoarthritis (OA), but its reliability and reproducibility are unclear. The purpose of this cross-sectional observer study was to investigate (1) the inter- and intraobserver agreement of evaluating pisotriquetral OA using pisotriquetral views with a special focus on sclerosis, joint space width (JSW) narrowing and osteophyte formation, and (2) the incidence of these latter radiographic features in patients suspected for pisotriquetral OA...
April 2017: Journal of Hand and Microsurgery
https://www.readbyqxmd.com/read/28428674/comparison-of-clinical-and-radiological-parameters-at-knee-osteoarthritis
#13
Adnana Talic-Tanovic, Zoran Hadziahmetovic, Ivanka Madjar-Simic, Adnan Papovic
INTRODUCTION: Osteoarthritis (OA) or arthrosis represents an inflammatory disease of joints that develops as a result of interaction of mechanical and biological parameters. With disease development, degenerative changes on joint cartilage can be noticeable that affect and cause pathological changes on other parts of a joint resulting in pain and dysfunction of a joint. A. E. Garrod in 1907 described osteoarthritis as a special clinical entity and separated it from a rheumatoid arthritis...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28425275/associations-between-obesity-and-the-radiographic-phenotype-in-knee-osteoarthritis
#14
Mehmet Derya Demirağ, Seçil Özkan, Şeminur Haznedaroğlu, Evin Aras Kilinç, Fatma Nur Baran Aksakal, Sefer Aycan, Berna Göker
BACKGROUND/AIM: Investigation of the association between obesity and the distinction of radiographic patterns in knee osteoarthritis. MATERIALS AND METHODS: Seven hundred and thirty-four women underwent weight-bearing antero-posterior knee radiography. Osteophytes and joint space narrowing (JSN) were graded according to the OARSI atlas. Each subject was assigned to one of the following groups with respect to the maximum score: osteophyte-dominant, indeterminate, JSN-dominant, and radiographically normal...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28410428/tuft1-a-novel-candidate-gene-for-metatarsophalangeal-osteoarthritis-plays-a-role-in-chondrogenesis-on-a-calcium-related-pathway
#15
Eeva Sliz, Mari Taipale, Maiju Welling, Sini Skarp, Viivi Alaraudanjoki, Jaakko Ignatius, Lloyd Ruddock, Ritva Nissi, Minna Männikkö
Osteoarthritis (OA) is the most common degenerative joint disorder and genetic factors have been shown to have a significant role in its etiology. The first metatarsophalangeal joint (MTP I) is highly susceptible to development of OA due to repetitive mechanical stress during walking. We used whole exome sequencing to study genetic defect(s) predisposing to familial early-onset bilateral MTP I OA inherited in an autosomal dominant manner. A nonsynonymous single nucleotide variant rs41310883 (c.524C>T, p...
2017: PloS One
https://www.readbyqxmd.com/read/28405725/the-posterolateral-approach-for-fluoroscopy-guided-tibiotalar-joint-injection
#16
Vanja Varenika, Jacob Harter, Edwin Chu, Lynne Steinbach
OBJECTIVE: To report a novel technique for tibiotalar joint injection that utilizes a posterolateral approach, including indications and technical considerations. METHODS: The posterolateral approach for tibiotalar injection is similar to that used in posterior subtalar joint injections. Using this technique, the tibiotalar joint space is accessed by directing the needle anterosuperiorly beneath the fibula until the posterior aspect of the talar dome has been reached...
April 12, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28399156/presence-of-il-17-in-synovial-fluid-identifies-a-potential-inflammatory-osteoarthritic-phenotype
#17
Sarah J B Snelling, Sylvette Bas, Gabor J Puskas, Stephanie G Dakin, Domizio Suva, Axel Finckh, Cem Gabay, Pierre Hoffmeyer, Andrew J Carr, Anne Lübbeke
PURPOSE: Osteoarthritis (OA) is a common and heterogeneous arthritic disorder. Patients suffer pain and their joints are characterized by articular cartilage loss and osteophyte formation. Risk factors for OA include age and obesity with inflammation identified as a key mediator of disease pathogenesis. Interleukin-17A (IL-17) is a pro-inflammatory cytokine that has been implicated in inflammatory diseases such as rheumatoid arthritis. IL-17 can upregulate expression of inflammatory cytokines and adipocytokines...
2017: PloS One
https://www.readbyqxmd.com/read/28397529/controlling-abnormal-joint-movement-inhibits-response-of-osteophyte-formation
#18
Kenji Murata, Takanori Kokubun, Yuri Morishita, Katsuya Onitsuka, Shuhei Fujiwara, Aya Nakajima, Tsutomu Fujino, Kiyomi Takayanagi, Naohiko Kanemura
Objective Osteoarthritis (OA) is induced by accumulated mechanical stress to joints; however, little has been reported regarding the cause among detailed mechanical stress on cartilage degeneration. This study investigated the influence of the control of abnormal joint movement induced by anterior cruciate ligament (ACL) injury in the articular cartilage. Design The animals were divided into 3 experimental groups: CAJM group ( n = 22: controlling abnormal joint movement), ACL-T group ( n = 22: ACL transection or knee anterior instability increased), and INTACT group ( n = 12: no surgery)...
April 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28394713/elbow-mri-findings-do-not-correlate-with-future-placement-on-the-disabled-list-in-asymptomatic-professional-baseball-pitchers
#19
Nicholas M Gutierrez, Christopher Granville, Lee Kaplan, Michael Baraga, Jean Jose
BACKGROUND: Injury rates among professional baseball players may reach as high as 5.8 per 1000 encounters, with pitchers being most vulnerable on account of the excessive biomechanical load on the upper extremity during the throwing motion. Anatomically, the shoulder is the most common site of pitching-related injury, accounting for 30.7% of injuries, closely followed by the elbow at 26.3%. Characteristic valgus loading imparts a predictable constellation of stresses on the joint, including medial tension, lateral compression, and posterior medial shearing...
April 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28388969/is-ct-indicated-in-diagnosing-sacroiliac-joint-degeneration
#20
J Bäcklund, E Clewett Dahl, M Skorpil
AIM: To assess the value of computed tomography (CT) in the diagnosis of symptomatic sacroiliac (SI) joint degeneration. MATERIALS AND METHODS: CT images from 123 patients with clinically diagnosed SI joint pain were compared to age- and gender-matched controls without chronic back pain or previous back surgery. Degeneration was graded assessing joint space narrowing, osteophytes, subchondral sclerosis, cysts, and vacuum phenomena. RESULTS: The mean total score for the patients was 9...
April 4, 2017: Clinical Radiology
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