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https://www.readbyqxmd.com/read/29350331/motion-deficit-in-nodal-interphalangeal-joint-osteoarthritis-by-digital-goniometer-in-housewives
#1
L Ventura-Ríos, M Hayes-Salinas, D Ferrusquia-Toriz, R I Cariño-Escobar, E Cruz-Arenas, J Gutiérrez-Martínez, L González-Ramírez, C Hernández-Díaz
Range of motion (ROM) measured objectively in nodal hand osteoarthritis (NHOA) is missing. Evaluation of collateral ligaments by ultrasound (US) is unknown in NHOA also. To compare ROM in interphalangeal joints in housewives with nodal OA, with a control group by a digital system using angle to voltage (Multielgon). The second objective was to assess correlation between collateral radial and ulnar ligaments thickness and ROM. For this cross-sectional observational study, we assessed 60 hands with symptomatic NHOA and 30 hands of healthy housewives matched for age...
January 19, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29349005/arthroscopic-elbow-osteocapsular-arthroplasty
#2
Manish S Noticewala, Maxwell A Levi, Christopher S Ahmad, William N Levine, Charles M Jobin
Treatment of primary elbow osteoarthritis in the young active patient less than 50 years old presents a treatment challenge to the practicing orthopaedic surgeon. Following failure of nonoperative management, surgical goals are aimed at reducing pain and improving joint mobility from bony impingement. Arthroscopic osteocapsular arthroplasty is a viable treatment option with few post-operative limitations. In contrast, total elbow arthroplasty is considered a salvage option in this patient population given the activity restrictions imposed...
December 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29326766/dorsal-luno-capitate-impingement-in-a-professional-tennis-player-a-case-report
#3
A Afshar, A Tabrizi
A 30-year old male right handed professional tennis player complained about reduced athletic performance, chronic pain and restricted extension of his right wrist. Lateral radiograph of the right wrist demonstrated an osteophyte projecting from the dorsal lip of the lunate bone. The presence of an osteophyte on the lateral radiograph of the lunate along with the history, clinical examination, intra-operative findings, and post-operative satisfactory result made the diagnosis of dorsal luno-capitate impingement syndrome reasonable...
November 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/29317848/traumatic-osteoarthritis-induced-persistent-mechanical-hyperalgesia-in-a-rat-model-of-anterior-cruciate-ligament-transection-plus-a-medial-meniscectomy
#4
Hsiao-Chien Tsai, Ta-Liang Chen, Yu-Pin Chen, Ruei-Ming Chen
Background: Osteoarthritis (OA) is a degenerative joint disease characterized by progressive cartilage degeneration, subchondral bone changes, osteophyte formation, and synovitis. A major symptom is pain that is triggered by peripheral and central changes within the pain pathways. Some surgery-induced joint instability rat models of OA were described to mimic traumatic OA. Several behavioral tests were developed to access OA-induced pain. However, follow-up in most studies usually only occurred for about 4 weeks...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29311696/reliable-landmarks-for-precise-topographical-analyses-of-pathological-structural-changes-of-the-ovine-tibial-plateau-in-2-d-and-3-d-subspaces
#5
Tamás Oláh, Jan Reinhard, Liang Gao, Lars K H Goebel, Henning Madry
Selecting identical topographical locations to analyse pathological structural changes of the osteochondral unit in translational models remains difficult. The specific aim of the study was to provide objectively defined reference points on the ovine tibial plateau based on 2-D sections of micro-CT images useful for reproducible sample harvesting and as standardized landmarks for landmark-based 3-D image registration. We propose 5 reference points, 11 reference lines and 12 subregions that are detectable macroscopically and on 2-D micro-CT sections...
January 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29304957/editorial-commentary-it-s-the-fracture-not-the-fragment-that-causes-the-pain-posteromedial-elbow-impingement-in-baseball-players
#6
EDITORIAL
Shawn W O'Driscoll
Posterior impingement pain in baseball players is typically due to a fractured olecranon osteophyte. Computed tomographic (CT) scanning is the imaging of choice when evaluating posterior or posteromedial elbow pain in athletes who have subjected the elbow to excessive stresses such as occur in overhead throwing and weightlifting. Sometimes the fracture fragment can be so small that it might not be detected on plain radiographs, magnetic resonance imaging, or even at the time of arthroscopy. Symptomatic fractured olecranon osteophytes can be diagnosed clinically with the extension impingement test or arm bar test...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29302780/effects-of-posterior-condylar-osteophytes-on-gap-balancing-in-computer-assisted-total-knee-arthroplasty-with-posterior-cruciate-ligament-sacrifice
#7
Pornpavit Sriphirom, Chaiyaporn Siramanakul, Boonyawat Chanopas, Sirisuk Boonruksa
OBJECTIVE: Gap planning in navigated total knee arthroplasty (TKA) is a critical concern. Osteophytes are normally removed prior to gap planning, with the exception of posterior condylar osteophytes of the femur, which are removed after posterior condylar resection. This study investigated how posterior condylar osteophytes affect gap balancing during surgery. METHODS: This prospective study was conducted on 40 primary varus osteoarthritic knees with a posterior condylar osteophyte that underwent TKA navigation...
January 4, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29301464/intervertebral-disc-degeneration-in-warmblood-horses-morphology-grading-and-distribution-of-lesions
#8
Wilhelmina Bergmann, Niklas Bergknut, Stefanie Veraa, Andrea Gröne, Hans Vernooij, Inge D Wijnberg, Willem Back, Guy C M Grinwis
Equine intervertebral disc degeneration is thought to be rare and of limited clinical relevance, although research is lacking. To objectively assess pathological changes of the equine intervertebral disc and their clinical relevance, description of the normal morphology and a practical, biologically credible grading scheme are needed. The objectives of this study are to describe the gross and histological appearance of the equine intervertebral discs and to propose a grading scheme for macroscopic degeneration...
January 1, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/29289433/comparison-between-several-ultrasound-hand-joint-scores-and-conventional-radiography-in-diagnosing-hand-osteoarthritis
#9
Priyanka Sivakumaran, Sidra Hussain, Coziana Ciurtin
This is the first study to investigate the usefulness of a standardized ultrasound (US) examination protocol in diagnosing hand osteoarthritis (OA). We conducted a cross-sectional study including 62 patients, ultimately diagnosed with hand OA based on imaging evidence of osteoarthritic changes with the particular distribution required for fulfilment of American College of Radiology diagnosis criteria. We compared a 32-joint US score (wrists, metacarpophalangeal [MCP], proximal interphalangeal [PIP] or distal interphalangeal [DIP] and carpometacarpal [CMC]-1 joints), with smaller, predefined joint scores, assessing 22 joints (wrists, MCPs and PIPs or PIPs, DIPs and CMC-1), 10 joints (MCP 2-3, PIP 2-3 and CMC-1 or PIP 2-3, DIP 2-3 and CMC-1) and 6 joints (DIP 2-3, CMC-1), respectively...
December 27, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/29287118/serum-n-propeptide-of-collagen-iia-piianp-as-a-marker-of-radiographic-osteoarthritis-burden
#10
Hikmat N Daghestani, Joanne M Jordan, Jordan B Renner, Michael Doherty, A Gerry Wilson, Virginia B Kraus
OBJECTIVE: Cartilage homeostasis relies on a balance of catabolism and anabolism of cartilage matrix. Our goal was to evaluate the burden of radiographic osteoarthritis and serum levels of type IIA procollagen amino terminal propeptide (sPIIANP), a biomarker representing type II collagen synthesis, in osteoarthritis. METHODS: OA burden was quantified on the basis of radiographic features as total joint faces with an osteophyte, joint space narrowing, or in the spine, disc space narrowing...
2017: PloS One
https://www.readbyqxmd.com/read/29276714/radiological-changes-in-the-cervical-spine-in-freshman-collegiate-sumo-wrestlers
#11
Yasuaki Nakagawa, Shogo Mukai, Kazufumi Minami, Yuji Hattori, Takashi Nakamura
Background: Sumo has long been a traditional sport in Japan and is rapidly attracting enthusiasts abroad. Sumo wrestling entails a risk of impact to the cervical spine during an initial charge. Few reports are available in the English-language literature regarding radiological changes in the cervical spine in sumo wrestlers. Purpose: To examine radiological changes in the cervical spine in freshmen collegiate sumo wrestlers. Study Design: Case series; Level of evidence, 4...
December 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29258883/cartilage-regeneration-and-ageing-targeting-cellular-plasticity-in-osteoarthritis
#12
REVIEW
Marta Varela-Eirin, Jesus Loureiro, Eduardo Fonseca, Silvia Corrochano, Jose R Caeiro, Manuel Collado, Maria D Mayan
Ageing processes play a major contributing role for the development of Osteoarthritis (OA). This prototypic degenerative condition of ageing is the most common form of arthritis and is accompanied by a general decline, chronic pain and mobility deficits. The disease is primarily characterized by articular cartilage degradation, followed by subchondral bone thickening, osteophyte formation, synovial inflammation and joint degeneration. In the early stages, osteoarthritic chondrocytes undergo phenotypic changes that increase cell proliferation and cluster formation and enhance the production of matrix-remodelling enzymes...
December 16, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/29246142/association-between-metabolic-syndrome-and-knee-osteoarthritis-a-cross-sectional-study
#13
Dong-Xing Xie, Jie Wei, Chao Zeng, Tuo Yang, Hui Li, Yi-Lun Wang, Hui-Zhong Long, Zi-Ying Wu, Yu-Xuan Qian, Kang-Hua Li, Guang-Hua Lei
BACKGROUND: Osteoarthritis (OA) is the most prevalent chronic joint disease in China. The aim of this study was to examine the association between metabolic syndrome (MetS) and knee OA in a population-based Chinese study. METHODS: Data included in this analysis is from a cross-sectional study, i.e., the Xiangya Hospital Health Management Center Study. MetS was diagnosed according to the criteria defined by the Chinese Diabetes Society. Radiographic knee OA was defined as changes equivalent to Kellgren-Lawrence (K-L) grade 2 or above at least one side...
December 16, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29244597/relationship-between-repository-radiographic-findings-and-subsequent-performance-of-quarter-horses-competing-in-cutting-events
#14
Myra F Barrett, C Wayne McIlwraith, Erin K Contino, Richard D Park, Christopher E Kawcak, David D Frisbie, James R zumBrunnen
OBJECTIVE To investigate potential associations between repository radiographic findings and subsequent performance of Quarter Horses competing in cutting events. DESIGN Retrospective cohort study. SAMPLE Repository radiographs (ie, radiographs obtained at the time of sale) for 343 client-owned horses. PROCEDURES Repository radiographic findings were compared with objective measures of performance, including the likelihood of competing; the likelihood of earning money as a 3-year-old, as a 4-year-old, and as a 3- and 4-year-old combined; and the amount of money earned as a 3-year-old, as a 4-year-old, and as a 3- and 4-year-old combined...
January 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29228639/role-of-melatonin-combined-with-exercise-as-a-switch-like-regulator-for-circadian-behavior-in-advanced-osteoarthritic-knee
#15
Yunkyung Hong, Hyunsoo Kim, Seunghoon Lee, Yunho Jin, Jeonghyun Choi, Sang-Rae Lee, Kyu-Tae Chang, Yonggeun Hong
Here, we show the role of melatonin combined with or without exercise as a determinant of multicellular behavior in osteoarthritis. We address the relationship between the molecular components governing local circadian clock and changes in the osteoarthritic musculoskeletal axis. Melatonin was injected subcutaneously in animals with advanced knee osteoarthritis (OA) for 4 weeks. Concurrently, moderate treadmill exercise was applied for 30 min/day. Morphometric, histological, and gene/protein-level analyses were performed in the cartilage, synovium, bone, and gastrocnemius muscle...
November 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/29205258/sustained-intra-cartilage-delivery-of-low-dose-dexamethasone-using-a-cationic-carrier-for-treatment-of-post-traumatic-osteoarthritis
#16
A G Bajpayee, R E De la Vega, M Scheu, N H Varady, I A Yannatos, L A Brown, Y Krishnan, T J Fitzsimons, P Bhattacharya, E H Frank, A J Grodzinsky, R M Porter
Disease-modifying osteoarthritis drugs (DMOADs) should reach their intra-tissue target sites at optimal doses for clinical efficacy. The dense, negatively charged matrix of cartilage poses a major hindrance to the transport of potential therapeutics. In this work, electrostatic interactions were utilised to overcome this challenge and enable higher uptake, full-thickness penetration and enhanced retention of dexamethasone (Dex) inside rabbit cartilage. This was accomplished by using the positively charged glycoprotein avidin as nanocarrier, conjugated to Dex by releasable linkers...
December 5, 2017: European Cells & Materials
https://www.readbyqxmd.com/read/29202806/risk-factors-for-joint-replacement-in-knee-osteoarthritis-a-15-year-follow-up-study
#17
Flemming K Nielsen, Niels Egund, Anette Jørgensen, Anne Grethe Jurik
BACKGROUND: To evaluate whether clinical, radiographic or MRI findings are associated with long term risk for total knee arthroplasty (TKA) in persons with knee osteoarthritis. METHODS: We performed a follow-up analysis of 100 persons with knee osteoarthritis who participated in a clinical trial between 2000 and 2002. Clinical data as well as radiography and MRI of the inclusion knee were obtained in all participants. Data on TKA procedures were extracted from The Danish National Patient Register...
December 4, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29201820/clinical-usefulness-of-x-ray-findings-for-non-specific-low-back-pain-in-korean-farmers-farm-study
#18
Eun Kyoung Kang, Hee-Won Park, Sung Hyun Kim, Sora Baek
Objective: To elucidate the association between non-specific low back pain (NSLBP) and spinal X-ray findings in Korean farmers: Farmers' Cohort for Agricultural Work-Related Musculoskeletal disorders (FARM) study. Methods: A total of 835 farmers (391 males, 444 females; mean age, 56.6±7.4 years) without red-flag signs of specific LBP were recruited. Presence of LBP more than one week or once a month with more than moderate degree of pain severity during the last year was assessed with a binary questionnaire (yes or no)...
October 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/29201635/successful-use-of-guanfacine-in-a-patient-with-chronic-refractory-cough-a-case-report
#19
Gregory W Kirschen, Howard Kirschen, Edward Gabalski, Jonathan M Waxner, Agnes Wohl
Chronic idiopathic cough is a common and often frustrating complaint for patients as well as providers. When common etiologies of cough are ruled out and/or do not respond to usual treatments, neurogenic cough should be considered as a diagnosis of exclusion. Here, we report on a 58-year-old woman with an 8-year history of chronic, treatment-refractory cough of unknown etiology that we diagnosed as neurogenic cough and successfully treated with guanfacine monotherapy, with rapid and durable improvement in symptoms...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/29190722/association-between-grip-strength-and-hand-and-knee-radiographic-osteoarthritis-in-korean-adults-data-from-the-dong-gu-study
#20
Lihui Wen, Min-Ho Shin, Ji-Hyoun Kang, Yi-Rang Yim, Ji-Eun Kim, Jeong-Won Lee, Kyung-Eun Lee, Dong-Jin Park, Tae-Jong Kim, Sun-Seog Kweon, Young-Hoon Lee, Yong-Woon Yun, Shin-Seok Lee
OBJECTIVES: We assessed whether grip strength was related to various types of radiographic damage in Korean adults with osteoarthritis (OA). METHODS: Data from 2,251 subjects enrolled in the Dong-gu study, who had no hand joint pain, were analyzed to investigate the relationship between grip strength and OA. Hand grip strength was measured using a hand-held dynamometer, and radiographs of the hand and knee were scored according to a semi-quantitative grading system...
2017: PloS One
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