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https://www.readbyqxmd.com/read/28428674/comparison-of-clinical-and-radiological-parameters-at-knee-osteoarthritis
#1
Adnana Talic-Tanovic, Zoran Hadziahmetovic, Ivanka Madjar-Simic, Adnan Papovic
INTRODUCTION: Osteoarthritis (OA) or arthrosis represents an inflammatory disease of joints that develops as a result of interaction of mechanical and biological parameters. With disease development, degenerative changes on joint cartilage can be noticeable that affect and cause pathological changes on other parts of a joint resulting in pain and dysfunction of a joint. A. E. Garrod in 1907 described osteoarthritis as a special clinical entity and separated it from a rheumatoid arthritis...
February 2017: Medical Archives
https://www.readbyqxmd.com/read/28425275/associations-between-obesity-and-the-radiographic-phenotype-in-knee-osteoarthritis
#2
Mehmet Derya Demirağ, Seçil Özkan, Şeminur Haznedaroğlu, Evin Aras Kilinç, Fatma Nur Baran Aksakal, Sefer Aycan, Berna Göker
BACKGROUND/AIM: Investigation of the association between obesity and the distinction of radiographic patterns in knee osteoarthritis. MATERIALS AND METHODS: Seven hundred and thirty-four women underwent weight-bearing antero-posterior knee radiography. Osteophytes and joint space narrowing (JSN) were graded according to the OARSI atlas. Each subject was assigned to one of the following groups with respect to the maximum score: osteophyte-dominant, indeterminate, JSN-dominant, and radiographically normal...
April 18, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28410428/tuft1-a-novel-candidate-gene-for-metatarsophalangeal-osteoarthritis-plays-a-role-in-chondrogenesis-on-a-calcium-related-pathway
#3
Eeva Sliz, Mari Taipale, Maiju Welling, Sini Skarp, Viivi Alaraudanjoki, Jaakko Ignatius, Lloyd Ruddock, Ritva Nissi, Minna Männikkö
Osteoarthritis (OA) is the most common degenerative joint disorder and genetic factors have been shown to have a significant role in its etiology. The first metatarsophalangeal joint (MTP I) is highly susceptible to development of OA due to repetitive mechanical stress during walking. We used whole exome sequencing to study genetic defect(s) predisposing to familial early-onset bilateral MTP I OA inherited in an autosomal dominant manner. A nonsynonymous single nucleotide variant rs41310883 (c.524C>T, p...
2017: PloS One
https://www.readbyqxmd.com/read/28405725/the-posterolateral-approach-for-fluoroscopy-guided-tibiotalar-joint-injection
#4
Vanja Varenika, Jacob Harter, Edwin Chu, Lynne Steinbach
OBJECTIVE: To report a novel technique for tibiotalar joint injection that utilizes a posterolateral approach, including indications and technical considerations. METHODS: The posterolateral approach for tibiotalar injection is similar to that used in posterior subtalar joint injections. Using this technique, the tibiotalar joint space is accessed by directing the needle anterosuperiorly beneath the fibula until the posterior aspect of the talar dome has been reached...
April 12, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28399156/presence-of-il-17-in-synovial-fluid-identifies-a-potential-inflammatory-osteoarthritic-phenotype
#5
Sarah J B Snelling, Sylvette Bas, Gabor J Puskas, Stephanie G Dakin, Domizio Suva, Axel Finckh, Cem Gabay, Pierre Hoffmeyer, Andrew J Carr, Anne Lübbeke
PURPOSE: Osteoarthritis (OA) is a common and heterogeneous arthritic disorder. Patients suffer pain and their joints are characterized by articular cartilage loss and osteophyte formation. Risk factors for OA include age and obesity with inflammation identified as a key mediator of disease pathogenesis. Interleukin-17A (IL-17) is a pro-inflammatory cytokine that has been implicated in inflammatory diseases such as rheumatoid arthritis. IL-17 can upregulate expression of inflammatory cytokines and adipocytokines...
2017: PloS One
https://www.readbyqxmd.com/read/28397529/controlling-abnormal-joint-movement-inhibits-response-of-osteophyte-formation
#6
Kenji Murata, Takanori Kokubun, Yuri Morishita, Katsuya Onitsuka, Shuhei Fujiwara, Aya Nakajima, Tsutomu Fujino, Kiyomi Takayanagi, Naohiko Kanemura
Objective Osteoarthritis (OA) is induced by accumulated mechanical stress to joints; however, little has been reported regarding the cause among detailed mechanical stress on cartilage degeneration. This study investigated the influence of the control of abnormal joint movement induced by anterior cruciate ligament (ACL) injury in the articular cartilage. Design The animals were divided into 3 experimental groups: CAJM group ( n = 22: controlling abnormal joint movement), ACL-T group ( n = 22: ACL transection or knee anterior instability increased), and INTACT group ( n = 12: no surgery)...
April 1, 2017: Cartilage
https://www.readbyqxmd.com/read/28394713/elbow-mri-findings-do-not-correlate-with-future-placement-on-the-disabled-list-in-asymptomatic-professional-baseball-pitchers
#7
Nicholas M Gutierrez, Christopher Granville, Lee Kaplan, Michael Baraga, Jean Jose
BACKGROUND: Injury rates among professional baseball players may reach as high as 5.8 per 1000 encounters, with pitchers being most vulnerable on account of the excessive biomechanical load on the upper extremity during the throwing motion. Anatomically, the shoulder is the most common site of pitching-related injury, accounting for 30.7% of injuries, closely followed by the elbow at 26.3%. Characteristic valgus loading imparts a predictable constellation of stresses on the joint, including medial tension, lateral compression, and posterior medial shearing...
April 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28388969/is-ct-indicated-in-diagnosing-sacroiliac-joint-degeneration
#8
J Bäcklund, E Clewett Dahl, M Skorpil
AIM: To assess the value of computed tomography (CT) in the diagnosis of symptomatic sacroiliac (SI) joint degeneration. MATERIALS AND METHODS: CT images from 123 patients with clinically diagnosed SI joint pain were compared to age- and gender-matched controls without chronic back pain or previous back surgery. Degeneration was graded assessing joint space narrowing, osteophytes, subchondral sclerosis, cysts, and vacuum phenomena. RESULTS: The mean total score for the patients was 9...
April 4, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28383601/temporomandibular-joint-involvement-in-rheumatoid-arthritis-patients-association-between-clinical-and-tomographic-data
#9
Patrícia Cf Cordeiro, Josemar P Guimaraes, Viviane A de Souza, Isabela M Dias, Jesca Nn Silva, Karina L Devito, Leticia L Bonato
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic inflammation and synovial hyperplasia, which usually affects multiple joints. The temporomandibular joint (TMJ) becomes susceptible to the development of changes resulting from RA. The aim of this study was to evaluate the presence of TMD and degenerative bone changes in TMJ in patients diagnosed with RA (rheumatoid arthritis). The Research Diagnostic Criteria for Temporomandibular Disorders (RDC/ TMD) questionnaire was used for clinical evaluation of the TMJ and for TMD classification of 49 patients of both sexes and all ages...
December 2016: Acta Odontológica Latinoamericana: AOL
https://www.readbyqxmd.com/read/28382392/porous-silicon-nitride-spacers-versus-peek-cages-for-anterior-cervical-discectomy-and-fusion-clinical-and-radiological-results-of-a-single-blinded-randomized-controlled-trial
#10
Mark P Arts, Jasper F C Wolfs, Terry P Corbin
PURPOSE: Anterior cervical discectomy with fusion is a common procedure for treating radicular arm pain. Polyetheretherketone (PEEK) plastic is a frequently used material in cages for interbody fusion. Silicon nitride is a new alternative with desirable bone compatibility and imaging characteristics. The aim of the present study is to compare silicon nitride implants with PEEK cages filled with autograft harvested from osteophytes. METHODS: The study is a prospective, randomized, blinded study of 100 patients with 2 years follow-up...
April 5, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28380089/relationship-between-articular-eminence-inclination-and-alterations-of-the-mandibular-condyle-a-cbct-study
#11
Saione Cruz Sa, Saulo Leonardo Sousa Melo, Daniela Pita de Melo, Deborah Queiroz Freitas, Paulo Sérgio Flores Campos
This study aimed at verifying the correlation among angulation of the articular eminence (AE), shape of the condyle and its degenerative bone diseases (DBDs), according to age and sex, through Cone Beam Computed Tomography (CBCT). Five hundred and twenty-eight temporomandibular joints (TMJ) were evaluated. The condyles were classified as: flat, convex, angled and rounded, and the AE angulation was measured. The DBDs evaluated were osteophytes, flattening, erosion, subcortical cysts and spinal sclerosis. There was no difference in the mean angulations in relation to age group (p>0...
March 30, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28367081/changes-of-articular-cartilage-and-subchondral-bone-after-extracorporeal-shockwave-therapy-in-osteoarthritis-of-the-knee
#12
Ching-Jen Wang, Jai-Hong Cheng, Wen-Yi Chou, Shan-Ling Hsu, Jen-Hung Chen, Chien-Yiu Huang
We assessed the pathological changes of articular cartilage and subchondral bone on different locations of the knee after extracorporeal shockwave therapy (ESWT) in early osteoarthritis (OA). Rat knees under OA model by anterior cruciate ligament transaction (ACLT) and medial meniscectomy (MM) to induce OA changes. Among ESWT groups, ESWT were applied to medial (M) femur (F) and tibia (T) condyles was better than medial tibia condyle, medial femur condyle as well as medial and lateral (L) tibia condyles in gross osteoarthritic areas (p<0...
2017: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/28363150/osteophyte-induced-lung-fibrosis-prevalence-and-osteophyte-qualities-predicting-disease
#13
Mary Salvatore, Claudia I Henschke, Rowena Yip, Sukhdeep Kaur, Kunwei Li, Maria Padilla, David Yankelevitz
OBJECTIVE: To determine the prevalence of osteophyte induced lung fibrosis (OIF) and its relationship to osteophyte size, location, and surrounding fat. METHODS: 94 CT scans of the chest were reviewed, size of the largest osteophyte and the presence of fibrosis were recorded. RESULTS: Presence of fibrosis was higher among patient with large (>10 mm) osteophytes compared to those with small (1-10mm) osteophytes. Age and presence of periosteophyte fat were significantly associated with presence of fibrosis...
February 28, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28361192/-malalignment-of-the-first-ray-clinical-and-radiological-diagnostics
#14
M Walther
Clinical and radiological examination of the foot are mandatory before surgical correction of the forefoot. The clinical examination includes leg axis, position of the hind foot, deformity of the first ray as well as skin conditions, pulse status and possible sensitive deficits. A shortening of the gastrocnemius muscle can be identified using the Silfverskiöld test. Discomfort in the midfoot can indicate pathologies of the tarsometatarsal joint and the same applies for osteophyte infiltration around the Lisfranc joint line, whereby the second tarsometatarsal joint often shows more advanced degenerative arthritis than the first tarsometatarsal joint...
March 30, 2017: Der Orthopäde
https://www.readbyqxmd.com/read/28359694/long-term-clinical-results-in-patients-treated-for-recurrent-posterolateral-elbow-joint-instability-using-an-ipsilateral-triceps-tendon-graft
#15
Christian Kastenskov, Jeppe Vejlgaard Rasmussen, Janne Ovesen, Bo Sanderhoff Olsen
BACKGROUND: The aim was to report the long-term functional and radiologic outcomes in patients treated for recurrent posterolateral elbow joint instability using an ipsilateral triceps tendon graft. METHODS: We included 18 patients previously treated for posterolateral elbow joint instability and evaluated for clinical results in 2003. Fifteen patients were examined with a mean follow-up period of 19 years (range, 17-22 years). We performed the clinical follow-up with clinical examination of stability, range of motion, pain score on a visual analog scale, Mayo Elbow Performance Score, and Danish version of Oxford Elbow Score...
March 27, 2017: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/28356645/the-study-of-elbow-injury-in-male-adult-kendo-players
#16
Shinya Kishi, Munehito Yoshida
[Purpose] Elbow injury in male adult kendo players was investigated and examined in order to obtain an indicator of prophylaxis of injury. [Subjects and Methods] The subjects were 22 male adult kendo players aged 25 to 60 years old, and presence or absence of pain, range of motion, and muscle strength in the elbow joints were investigated. In addition, among athletes with limited range of motion (ROM) in the elbow joints, three athletes who had received an explanation and had provided informed consent underwent CT, and the images were examined...
March 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28356146/do-the-disc-degeneration-and-osteophyte-contribute-to-the-curve-rigidity-of-degenerative-scoliosis
#17
Feng Zhu, Hongda Bao, Peng Yan, Shunan Liu, Mike Bao, Zezhang Zhu, Zhen Liu, Yong Qiu
BACKGROUND: The factors associated with lateral curve flexibility in degenerative scoliosis have not been well documented. Disc degeneration could result in significant change in stiffness and range of motion in lateral bending films. The osteophytes could be commonly observed in degenerative spine but the relationship between osteophyte formation and curve flexibility remains controversial. The aim of the current study is to clarify if the disc degeneration and osteophyte formation were both associated with curve flexibility of degenerative scoliosis...
March 29, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28348071/acromegalic-arthropathy-in-various-stages-of-the-disease-a-magnetic-resonance-imaging-mri-study
#18
Kim M J A Claessen, A Navas Canete, P De Bruin, Alberto M Pereira, M Kloppenburg, H Kroon, N R Biermasz
Background Arthropathy is a prevalent and invalidating complication of acromegaly with a characteristic radiographic phenotype. We aimed to further characterize cartilage and bone abnormalities associated with acromegalic arthropathy using Magnetic Resonance (MR) imaging. Methods Twenty-six patients (23% women, mean age 56.8±13.4yr), with active (N=10) and controlled acromegaly (N=16) underwent a 3.0T MRI of the right knee. Osteophytes, cartilage defects, bone marrow lesions, and subchondral cysts were assessed by KOSS (Knee Osteoarthritis Scoring System)...
March 27, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28345597/post-traumatic-osteoarthritis-in-mice-following-mechanical-injury-to-the-synovial-joint
#19
Muhammad Farooq Rai, Xin Duan, James D Quirk, Nilsson Holguin, Eric J Schmidt, Nobuaki Chinzei, Matthew J Silva, Linda J Sandell
We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in response to mechanical injury. We hypothesized that alteration in knee joint stability in mice reproduces molecular and structural features of PTOA that would suggest potential therapeutic targets in humans. The right knees of eight-week old male mice from two recombinant inbred lines (LGXSM-6 and LGXSM-33) were subjected to axial tibial compression. Three separate loading magnitudes were applied: 6N, 9N, and 12N...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28345403/intralesional-osteophyte-regrowth-following-autologous-chondrocyte-implantation-after-previous-treatment-with-marrow-stimulation-technique
#20
Marco Kawamura Demange, Tom Minas, Arvind von Keudell, Sonal Sodha, Tim Bryant, Andreas H Gomoll
Objective Bone marrow stimulation surgeries are frequent in the treatment of cartilage lesions. Autologous chondrocyte implantation (ACI) may be performed after failed microfracture surgery. Alterations to subchondral bone as intralesional osteophytes are commonly seen after previous microfracture and removed during ACI. There have been no reports on potential recurrence. Our purpose was to evaluate the incidence of intralesional osteophyte development in 2 cohorts: existing intralesional osteophytes and without intralesional osteophytes at the time of ACI...
April 2017: Cartilage
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