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https://www.readbyqxmd.com/read/28436656/cellulose-anionic-hydrogels-based-on-cellulose-nanofibers-as-natural-stimulants-for-seed-germination-and-seedling-growth
#1
Hao Zhang, Minmin Yang, Qian Luan, Hu Tang, Fenghong Huang, Xia Xiang, Chen Yang, Yuping Bao
Cellulose anionic hydrogels were successfully prepared from dissolving Tempo-oxidized cellulose nanofibers in NaOH/urea aqueous solution and then crosslinked with epichlorohydrin. The hydrogels exhibit microporous structure and high hydrophilicity, contribute to the excellent water absorption property. The growth indexes including the germination rate, root length, shoot length, fresh weight and dry weight of seedlings were investigated and the cellulose anionic hydrogel showed no significant difference compared with soil medium...
April 24, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28436604/solvent-free-mechanochemical-synthesis-of-nitrogen-doped-nanoporous-carbon-for-electrochemical-energy-storage
#2
Christina Schneidermann, Nicolas Jaeckel, Steffen Oswald, Lars Giebeler, Volker Presser, Lars Borchardt
Nitrogen-doped nanoporous carbons have been synthesized by a solvent-free mechanochemically-induced one-pot synthesis. This facile approach involves the mechanochemical treatment and carbonization of three solid materials: potassium carbonate, urea, and lignin, which is a waste product from pulp industry. The resulting nitrogen-doped porous carbons offer a very high specific surface area up to 3000 m2 g-1 and large pore volume up to 2 cm3 g-1. The mechanochemical reaction and the impact of activation and functionalization are investigated by nitrogen- and water physisorption and high-resolution X-ray photoelectron spectroscopy (XPS)...
April 24, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28436343/implications-of-feed-concentrate-reduction-in-organic-grassland-based-dairy-systems-a-long-term-on-farm-study
#3
F Leiber, I K Schenk, A Maeschli, S Ivemeyer, J O Zeitz, S Moakes, P Klocke, P Staehli, C Notz, M Walkenhorst
In response to increasing efforts for reducing concentrate inputs to organic dairy production in grassland-rich areas of Europe, a long-term study was conducted, which assessed the impacts of concentrate reductions on cows' performance, health, fertility and average herd age. In total, 42 Swiss commercial organic dairy cattle farms were monitored over 6 years ('Y0', 2008/09 until 'Y5', 2013/14). In comparison with overall data of Swiss herdbooks (including conventional and organic farms), the herds involved in the project had lower milk yields, similar milk solids, shorter calving intervals and higher average lactation numbers...
April 24, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28436220/metal-free-organocatalytic-oxidative-ugi-reaction-promoted-by-hypervalent-iodine
#4
Karandeep Singh, Amanpreet Kaur, Venus Singh Mithu, Siddharth Sharma
We report here a novel IBX promoted oxidative coupling of primary amines and its utilization to Ugi reaction. Advantageously, the reaction could be carried out in choline chloride-urea as a natural deep eutectic solvent. A range of imines and bis-amides from pseudo-four component oxidative Ugi reaction could be synthesized under mild and metal-free conditions. Advantageously, the oxidant (IBX) and solvent could be recycled up to five times with only a slight loss in activity.
April 24, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28435894/oral-bacterial-acid-base-metabolism-in-caries-screening-a-proof-of-concept-study
#5
E Morou-Bermudez, M A Loza-Herrero, V Garcia-Rivas, E Suarez-Perez, R J Billings
The objective of this cross-sectional study was to clinically validate an array of biochemical tests for oral acid/alkali generation as caries screening instruments. 185 adult subjects (mean 33.6±10.6 years) were examined clinically for dental caries using the ICDAS criteria. Bitewing radiographs were used to confirm interproximal surfaces of posterior teeth. For the purposes of this study, subjects were classified as "caries-active" if they had at least one untreated caries lesion with ICDAS 4 or higher. Pooled supragingival plaque and unstimulated saliva samples were collected and assayed for pH changes from sucrose and urea metabolism using colorimetric tests...
April 2017: JDR Clinical and Translational Research
https://www.readbyqxmd.com/read/28435491/agreement-between-serum-assays-performed-in-ed-point-of-care-and-hospital-central-laboratories
#6
Meir Dashevsky, Steven L Bernstein, Carol L Barsky, Richard A Taylor
INTRODUCTION: Point-of-care (POC) testing allows for more time-sensitive diagnosis and treatment in the emergency department (ED) than sending blood samples to the hospital central laboratory (CL). However, many ED patients have blood sent to both, either out of clinical custom, or because clinicians do not trust the POC values. The objective of this study was to examine the level of agreement between POC and CL values in a large cohort of ED patients. METHODS: In an urban, Level I ED that sees approximately 120,000 patients/year, all patients seen between March 1, 2013, and October 1, 2014, who had blood sent to POC and CL labs had levels of agreement measured between serum sodium, potassium, blood urea nitrogen (BUN), creatinine, and hematocrit...
April 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28435308/association-of-the-ppp3ca-c-249g-a-variant-with-clinical-outcomes-of-tacrolimus-based-therapy-in-kidney-transplant-recipients
#7
Patricia C Salgado, Fabiana Dv Genvigir, Claudia R Felipe, Helio Tedesco-Silva, Jose O Medina-Pestana, Sonia Q Doi, Mario H Hirata, Rosario Dc Hirata
BACKGROUND: The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate the influence of the PPP3CA c.249G>A variant on the clinical outcomes of kidney transplant recipients. PATIENTS AND METHODS: A total of 148 Brazilian patients received tacrolimus (TAC)-based immunosuppressive therapy for 90 days post-kidney transplantation...
2017: Pharmacogenomics and Personalized Medicine
https://www.readbyqxmd.com/read/28435196/hemato-biochemical-alterations-and-urinalysis-in-dogs-suffering-from-benign-prostatic-hyperplasia
#8
M R Das, R C Patra, R K Das, P K Rath, B P Mishra
AIM: The study was designed to evaluate the hemato-biochemical alterations, urinalysis along with histomorphological and histological changes of prostate glands in dogs affected with benign prostatic hyperplasia (BPH) in and around Bhubaneswar, Odisha, India. MATERIALS AND METHODS: In toto, 445 dogs presented to the Teaching Veterinary Clinical Complex of the College of Veterinary Sciences and Animal Husbandry, one Government Veterinary Hospital and two pet clinics in and around Bhubaneswar screened for the presence of BPH...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28435064/salvianolate-attenuates-renal-fibrosis-in-rat-models-of-diabetic-nephropathy-by-inhibiting-inflammation-and-oxidative-stress-mechanisms
#9
Chongxiang Xiong, Jianrao Lu, Xinhua Wang, Monica V Masucci
OBJECTIVE: Mounting evidence has shown that inflammation and oxidative stress are involved in the development and progression of diabetic nephropathy. Salvianolate is proven to have multiple bioactivities including anti-inflammation and anti-oxidative stress effects in diverse diseases. However, its role in rat models of diabetic nephropathy remains unclear. METHODS: In this study, we examined the renoprotective effect of Salvianolate on rat models of diabetic nephropathy induced by streptozotocin intraperitoneal injection...
April 20, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28434225/in-depth-proteome-coverage-by-improving-efficiency-for-membrane-proteome-analysis
#10
Qun Zhao, Fei Fang, Yichu Shan, Zhigang Sui, Baofeng Zhao, Zhen Liang, Lihua Zhang, YuKui Zhang
Although great achievement has been made in the mapping of human proteome, the efficiency of sample preparation still needs to be improved, especially for membrane proteins. Herein, we presented a novel method to deepen proteome coverage by the sequential extraction of proteins using urea and 1-dodecyl-3- methylimidazoliumchloride (C12Im-Cl). With such a strategy, the commonly lost hydrophobic proteins by 8 M urea extraction could be further recovered by C12Im-Cl, as well as the suppression effect of high abundance soluble proteins could be decreased...
April 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28434062/nlophoric-3-6-di-substituted-quinoxalin-carbazoles-synthesis-photophysical-properties-and-dft-studies
#11
Rahul D Telore, Amol G Jadhav, Nagaiyan Sekar
Synthesis of novel 3,6-di(substituted quinoxalin) carbazole fluorophores by the condensation of 1,1'-(9-ethyl-9H-carbazole-3,6-diyl)bis(2-bromoethanone) with methyl, chloro and unsubstituted o-phenylenediamine is presented. Synthesized derivatives are well characterized by (1)H NMR, (13)C NMR, FTIR and Mass spectroscopy. Photophysical studies are carried out using solvents of varying polarities revealed positive solvatochromism and intramolecular charge transfer from carbazole (Donor) to quinoxalin (Acceptor)...
April 22, 2017: Journal of Fluorescence
https://www.readbyqxmd.com/read/28434010/dynamic-analysis-of-kidney-function-and-its-correlation-with-nutritional-indicators-in-a-large-sample-of-hospitalized-elderly-patients
#12
Li Qingping, Wei Ribao, Wang Yang, Su Tingyu, Yang Xi, Huang Mengjie, Miao Hui, Chen Xiangmei
BACKGROUND The aim of this study was to analyze changes in kidney function and its correlation with nutritional metabolism indicators in hospitalized elderly patients in a large medical center over the past 7 years. MATERIAL AND METHODS The renal function of patients over 60 years old in the Chinese PLA General Hospital in 2008, 2011, and 2014 were comparatively analyzed. The hemoglobin, serum albumin, triglycerides, cholesterol, uric acid, and urea nitrogen data were collected and used as the nutritional metabolism indicators...
April 23, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28433992/the-aachen-minipig-phenotype-genotype-hematological-and-biochemical-characterization-and-comparison-to-the-g%C3%A3-ttingen-minipig
#13
Kerstin Pawlowsky, Lisa Ernst, Julia Steitz, Thaddäus Stopinski, Babette Kögel, Anna Henger, Reinhart Kluge, René Tolba
BACKGROUND: The pig is one of the most frequently used large animal models for biomedical research, especially in the field of translational research and surgical models. While standard livestock breeds are used in short-term and acute studies, minipig breeds are the preferred breeds in long-term and chronic studies due to their limited growth and body weight. OBJECTIVE: In consideration of the 3R principle (refinement, reduction, replacement) and the increasing demand, the aim of this study was to generate a new, robust, non-specific-pathogen-free minipig breed, the Aachen minipig...
April 22, 2017: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/28433936/sustained-viral-gene-delivery-from-a-micro-fibrous-elastomeric-cardiac-patch-to-the-ischemic-rat-heart
#14
Xinzhu Gu, Yasumoto Matsumura, Ying Tang, Souvik Roy, Richard Hoff, Bing Wang, William R Wagner
Biodegradable and elastomeric patches have been applied to the surface of infarcted hearts as temporary mechanical supports to effectively alter adverse left ventricular remodeling processes. In this report, recombinant adeno-associated virus (AAV), known for its persistent transgene expression and low pathogenicity, was incorporated into elastomeric polyester urethane urea (PEUU) and polyester ether urethane urea (PEEUU) and processed by electrospinning into two formats (solid fibers and core-sheath fibers) designed to influence the controlled release behavior...
April 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28433901/significantly-enhanced-enzymatic-hydrolysis-of-rice-straw-via-a-high-performance-two-stage-deep-eutectic-solvents-synergistic-pretreatment
#15
Xue-Dan Hou, Guo-Jian Feng, Mei Ye, Chao-Mei Huang, Yi Zhang
A two-stage deep eutectic solvents (DESs) treatment was shown to be an effective method for improving the utilization of certain DESs, and the specific order of pretreatment, such as malic acid/proline (MP) or choline chloride/oxalic acid (CO) during the first stage and choline chloride/urea (CU) during the second stage, resulted in better performance for enhancing the sugar yield due to the synergistic effect of the two DESs on biomass fractionation. Moreover, the presence of water during these processes could balance the loss of components by tuning the pretreatment severity, thus ensuring higher sugar yields...
April 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28433804/crocin-attenuates-hemorrhagic-shock-induced-oxidative-stress-and-organ-injuries-in-rats
#16
Long Yang, Xiujuan Dong
We aimed to evaluate the effect of natural antioxidant crocin in alleviating hemorrhagic shock (HS)-induced organ damages. HS rats were treated with crocin during resuscitation. Mortality at 12h and 24h post resuscitation was documented. HS and resuscitation induced organ injuries, as characterized by elevated wet/dry ratio, quantitative assessment ratio, blood urea nitrogen, creatinine, aspartate aminotransferase and alanine aminotransferase, whereas rats received crocin treatment demonstrated improvements in all the above characteristics...
April 13, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28433747/chemical-composition-of-ocimum-sanctum-by-lc-esi-ms-ms-analysis-and-its-protective-effects-against-smoke-induced-lung-and-neuronal-tissue-damage-in-rats
#17
M P Venuprasad, Hemanth Kumar Kandikattu, Sakina Razack, Narayanappa Amruta, Farhath Khanum
Smoke induced oxidative stress is known to cause various cancers and associated health problems including lung cancer. Herbal extracts have been reported as antioxidant supplements which attenuate free radical induced oxidative damage of tissues, among which Ocimum sanctum has been reported as the elixir of life due to its innumerable health benefits. In the present study, we investigated the protective effect of O. sanctum against cracker smoke induced lung and brain tissue damage. The results of the study demonstrate that O...
April 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28433638/metabolomic-analysis-for-combined-hepatotoxicity-of-chlorpyrifos-and-cadmium-in-rats
#18
Ming-Yuan Xu, Pan Wang, Ying-Jian Sun, Yi-Jun Wu
Pesticides and heavy metals are widespread environmental pollutants. Although the acute toxicity of organophosphorus pesticide chlorpyrifos (CPF) and toxic heavy metal cadmium (Cd) is well characterized, the combined toxicity of CPF and Cd, especially the hepatotoxicity of the two chemicals with long-term exposure at a low dose, remained unclear. In this study, we investigated the toxicity in the liver of rats upon subchronic exposure to CPF and Cd at environmentally relevant doses. Rats were given three different doses (1/135 LD50, 1/45 LD50 and 1/15 LD50) of CPF and Cd as well as their mixtures by oral gavage for 90 days...
April 19, 2017: Toxicology
https://www.readbyqxmd.com/read/28433338/morbidity-of-endovascular-abdominal-aortic-aneurysm-repair-is-directly-related-to-diameter
#19
Douglas M Overbey, Natalia O Glebova, Brandon C Chapman, Patrick W Hosokawa, John C Eun, Mark R Nehler
OBJECTIVE: Previous randomized controlled trials have defined specific size thresholds to guide surgical decision-making in patients presenting with an abdominal aortic aneurysm (AAA). With recent advances in endovascular techniques, the anatomic considerations of AAA repair are rapidly changing. Our specific aims were to evaluate the most recent national population data to compare anatomic differences and perioperative outcomes in patients with AAA. METHODS: The American College of Surgeons National Surgical Quality Improvement Program was queried from 2011 to 2015 using the targeted vascular public use file...
April 19, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28433179/isolation-of-cellulose-nanocrystals-from-medium-density-fiberboards
#20
Jin Gu, Chuanshuang Hu, Rui Zhong, Dengyun Tu, Hong Yun, Weiwei Zhang, Shao-Yuan Leu
Cellulose fibers have been successfully isolated from medium density fiberboards (MDFs) by sodium chlorite oxidation-potassium hydroxide (NaClO2-KOH) leaching process, at 37.6% yield, comparable to the 39.3% and 37.3% cellulose fibers from eucalyptus and eucalyptus with 12% cured urea-formaldehyde (UF) resin, respectively. At the same sulfuric acid hydrolysis conditions (65% H2SO4, 60°C and 30min), MDF cellulose nanocrystals (CNCs) were produced at 27.5% yield, similar to 27.4% of CNC yield from eucalyptus with UF resin, but less than 31...
July 1, 2017: Carbohydrate Polymers
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