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https://www.readbyqxmd.com/read/28749489/optimization-of-ultra-performance-liquid-chromatography-uplc-with-fluorescence-detector-fld-method-for-the-quantitative-determination-of-selected-neurotransmitters-in-rat-brain
#1
Joanna Stragierowicz, Adam Daragó, Sławomir Brzeźnicki, Anna Kilanowicz
BACKGROUND: Glutamate (Glu) and γ-aminobutyric acid (GABA) are the main neurotransmitters in the central nervous system for excitatory and inhibitory processes, respectively. Monitoring these neurotransmitters is an essential tool in establishing pathological functions, among others in terms of occupational exposure to toxic substances. MATERIAL AND METHODS: We present modification of the HPLC (high-performance liquid chromatography) to the UPLC (ultra-performance liquid chromatography) method for the simultaneous determination of glutamate and γ-aminobutyric acid in a single injection...
July 26, 2017: Medycyna Pracy
https://www.readbyqxmd.com/read/28749340/super-resolution-imaging-of-synaptic-and-extra-synaptic-ampa-receptors-with-different-sized-fluorescent-probes
#2
Sang Hak Lee, Chaoyi Jin, En Cai, Pinghua Ge, Yuji Ishitsuka, Kai Wen Teng, Andre A de Thomaz, Duncan L Nall, Murat Baday, Okunola Jeyifous, Daniel Demonte, Christopher M Dundas, Sheldon Park, Jary Y Delgado, William N Green, Paul R Selvin
Previous studies tracking AMPA receptor (AMPAR) diffusion at synapses observed a large mobile extrasynaptic AMPAR pool. Using super-resolution microscopy, we examined how fluorophore size and photostability affected AMPAR trafficking outside of, and within, post-synaptic densities (PSDs) from rats. Organic fluorescent dyes (≈4 nm), quantum dots, either small (≈10 nm diameter; sQDs) or big (>20 nm; bQDs), were coupled to AMPARs via different-sized linkers. We find that >90% of AMPARs labeled with fluorescent dyes or sQDs were diffusing in confined nanodomains in PSDs, which were stable for 15 minutes or longer...
July 27, 2017: ELife
https://www.readbyqxmd.com/read/28749105/compensation-for-asbestos-related-diseases-in-japan-utilization-of-standard-classifications-of-industry-and-occupations
#3
Kittisak Sawanyawisuth, Sugio Furuya, Eun-Kee Park, Jun-Pyo Myong, Juan Pablo Ramos-Bonilla, Odgerel Chimed Ochir, Ken Takahashi
Background: Asbestos-related diseases (ARD) are occupational hazards with high mortality rates. To identify asbestos exposure by previous occupation is the main issue for ARD compensation for workers. This study aimed to identify risk groups by applying standard classifications of industries and occupations to a national database of compensated ARD victims in Japan. Methods: We identified occupations that carry a risk of asbestos exposure according to the International Standard Industrial Classification of All Economic Activities (ISIC)...
July 27, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28748983/design-planning-and-management-of-the-hospital-custody-unit-at-hospital-universitario-fundaci%C3%A3-n-alcorc%C3%A3-n
#4
C de la Fuente-Martín, B de la Fuente Martín, E Grifol-Clar
OBJECTIVE: The design and management of a Hospital Custody Unit at Hospital Universitario Fundación Alcorcón, to focus the aim of this study on specialized medical care for extra-penitentiary patients who have suffered from a disease. We are building a new space to facilitate their daily lives at hospital and we want to offer a double function to the patients that consists of a custody space and a health rehabilitation space. MATERIAL AND METHODS: We carried out a scientific literature search on the international and national databases, about Hospital Custody Units or Restricted Access Units...
December 2017: Revista Española de Sanidad Penitenciaria
https://www.readbyqxmd.com/read/28748563/intra-hospital-transfers-and-adverse-patient-outcomes-an-analysis-of-administrative-health-data
#5
Nicole Blay, Michael Roche, Christine Duffield, Xiaoyue Xu
AIMS AND OBJECTIVES: To determine whether there was an association between intra-hospital transfers and adverse outcomes. BACKGROUND: Transfers between clinical units and between beds on the same unit are routine aspects of an episode of care in acute hospitals. The rate of these transfers per episode has increased in response to high occupancy levels, a decline in bed numbers, and increased demand for hospital services. The impact of the number of transfers between both wards and beds on patient outcomes is not widely explored...
July 26, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28747727/metal-free-ternary-bcn-nanosheets-with-synergetic-effect-of-band-gap-engineering-and-magnetic-properties
#6
Changlong Sun, Fukun Ma, Liang Cai, Aizhu Wang, Yongzhong Wu, Mingwen Zhao, Wensheng Yan, Xiaopeng Hao
Introducing the synergy effect of magnetic properties and band gap engineering is highly desired for two-dimensional (2D) nanosheets. Here, we prepare metal-free ternary 2D carbon (C) doped boron nitride (BN) nanosheets (BCN) with band gap engineering and magnetic properties by a synergetic way. The substitutional occupation of C atoms, as revealed by X-ray absorption spectrum, in BCN nanosheets induces tunable band gap reduction (5.5 eV to 2.6 eV) and intensive intrinsic ferromagnetism at room temperature...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747293/improving-employee-well-being-and-effectiveness-systematic-review-and-meta-analysis-of-web-based-psychological-interventions-delivered-in-the-workplace
#7
Stephany Carolan, Peter R Harris, Kate Cavanagh
BACKGROUND: Stress, depression, and anxiety among working populations can result in reduced work performance and increased absenteeism. Although there is evidence that these common mental health problems are preventable and treatable in the workplace, uptake of psychological treatments among the working population is low. One way to address this may be the delivery of occupational digital mental health interventions. While there is convincing evidence for delivering digital psychological interventions within a health and community context, there is no systematic review or meta-analysis of these interventions in an occupational setting...
July 26, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28747235/journalists-occupational-stress-a-comparative-study-between-reporting-critical-events-and-domestic-news
#8
Susana Monteiro, Alexandra Marques-Pinto
Nowadays, journalism is considered a stressful occupation, not only due to the stress perceived in journalists' daily work but also due to the critical, potentially traumatic events they report. However, research on journalists' occupational stress in both these professional settings is still scarce. This study aims to characterize and compare occupational stress variables perceived by journalists in their daily work and in critical scenarios. Taking the Holistic Model of Occupational Stress by Nelson and Simmons (2003) as a framework, 25 Portuguese journalists, all with experience in reporting critical events, were interviewed on their perceptions of some core variables of the model: occupational stressors, distress and eustress emotional reactions, and the consequences of these experiences on their well-being...
July 27, 2017: Spanish Journal of Psychology
https://www.readbyqxmd.com/read/28747193/impact-of-improved-recording-of-work-relatedness-in-primary-care-visits-at-occupational-health-services-on-sickness-absences-study-protocol-for-a-randomised-controlled-trial
#9
Salla Atkins, Ulla Ojajärvi, Nina Talola, Mervi Viljamaa, Jaakko Nevalainen, Jukka Uitti
BACKGROUND: Employment protects and fosters health. Occupational health services, particularly in Finland, have a central role in protecting employee health and preventing work ability problems. However, primary care within occupational health services is currently underused in informing preventive activities. This study was designed to assess whether the recording of work ability problems and improvement of follow-up of work-related primary care visits can reduce sickness absences and work disability pensions after 1 year...
July 26, 2017: Trials
https://www.readbyqxmd.com/read/28747138/perspectives-on-rehabilitation-of-children-with-cerebral-palsy-exploring-a-cross-cultural-view-of-parents-from-india-and-canada-using-the-international-classification-of-functioning-disability-and-health
#10
Pranay Jindal, Joy C MacDermid, Peter Rosenbaum, Briano DiRezze, Amitesh Narayan
PURPOSE: To explore parents' perspectives on rehabilitation of their child with cerebral palsy and their information needs. METHODS: Semistructured interviews were conducted with parents of children with CP from India (n = 11) and Canada (n = 7). Data were analyzed through an interpretive description approach using the International Classification of Functioning, Disability and Health framework. RESULTS: Body Structure and Function: Indian parents were more focused on fixing body structure and function challenges, and independent walking, than Canadian parents...
July 26, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28746952/-return-to-work-after-disk-surgery-influenced-by-rehabilitation
#11
Julia Dannenmaier, Sabrina Ritter, Silke Jankowiak, Rainer Kaluscha, Gert Krischak
Objective The aim of this study was a comparison of treatment results in the year after disk surgery between the following treatment groups: rehabilitation immediately after discharge from hospital, rehabilitation with a transition time (at home) up to twenty days after rehabilitation or no rehabilitation. Methods On basis of claims data from a statutory health insurance and the German Federal Pension Fund the comparison of treatment results was performed. Therefore, duration of disability, return to work and early retirement are considered as treatment results and are analyzed using general linear models (GLM)...
July 26, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28746895/effects-on-human-bronchial-epithelial-cells-following-low-dose-chronic-exposure-to-nanomaterials-a-6-month-transformation-study
#12
Santosh Phuyal, Mayes Kasem, Laura Rubio, Hanna L Karlsson, Ricard Marcos, Vidar Skaug, Shanbeh Zienolddiny
The most plausible exposure route to manufactured nanomaterials (MNM) remains pulmonary inhalation. Yet, few studies have attempted to assess carcinogenic properties in vitro following long-term exposure of human pulmonary cells to low and occupationally relevant doses. The most advanced in vitro tests for carcinogenicity, the cell transformation assay (CTA), relying mostly on rodent cells and short-term exposure. We hypothesized that long-term exposure of human bronchial epithelial cells with a normal phenotype could be a valuable assay for testing carcinogenicity of nanomaterials...
July 23, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28746865/polycomb-responds-to-low-levels-of-transcription
#13
Georgina Berrozpe, Gene O Bryant, Katherine Warpinski, Dan Spagna, Santosh Narayan, Shivangi Shah, Mark Ptashne
How is Polycomb (Pc), a eukaryotic negative regulator of transcription, targeted to specific mammalian genes? Our genome-wide analysis of the Pc mark H3K27me3 in murine cells revealed that Pc is preferentially associated with CpG island promoters of genes that are transcribed at a low level and less so with promoters of genes that are either silent or more highly expressed. Studies of the CpG island promoter of the Kit gene demonstrate that Pc is largely absent when the gene is silent in myeloid cells, as well as when the gene is highly expressed in mast cells...
July 25, 2017: Cell Reports
https://www.readbyqxmd.com/read/28746705/risk-of-suicide-attempt-among-soldiers-in-army-units-with-a-history-of-suicide-attempts
#14
Robert J Ursano, Ronald C Kessler, James A Naifeh, Holly Herberman Mash, Carol S Fullerton, Paul D Bliese, Alan M Zaslavsky, Tsz Hin Hinz Ng, Pablo A Aliaga, Gary H Wynn, Hieu M Dinh, James E McCarroll, Nancy A Sampson, Tzu-Cheg Kao, Michael Schoenbaum, Steven G Heeringa, Murray B Stein
Importance: Mental health of soldiers is adversely affected by the death and injury of other unit members, but whether risk of suicide attempt is influenced by previous suicide attempts in a soldier's unit is unknown. Objective: To examine whether a soldier's risk of suicide attempt is influenced by previous suicide attempts in that soldier's unit. Design, Setting, and Participants: Using administrative data from the Army Study to Assess Risk and Resilience in Servicemembers (STARRS), this study identified person-month records for all active-duty, regular US Army, enlisted soldiers who attempted suicide from January 1, 2004, through December 31, 2009 (n = 9650), and an equal-probability sample of control person-months (n = 153 528)...
July 26, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28746623/extreme-cultural-persistence-in-eastern-central-brazil-the-case-of-lagoa-santa-paleaeoindians
#15
Astolfo G M Araujo, Francisco A Pugliese, Rafael O Dos Santos, Mercedes Okumura
Lapa do Santo rockshelter, a Paleoindian site located in Eastern-Central Brazil, presented two main occupations; one during Early Holocene (12,460 to 8700 cal BP), and a latter in Middle Holocene (5100 to 4200 cal BP). In spite of this 3600 year gap, the stratigraphy and general characteristics of the material culture did not indicate any visible discontinuity. This led us to hypothesise a reoccupation of the rockshelter by the same cultural group, tested by means of statistical analyses comparing lithics, bone artifacts, and faunal remains from early and middle Holocene layers...
July 24, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28746571/insufficient-free-time-physical-activity-and-occupational-factors-in-brazilian-public-school-teachers
#16
Douglas Fernando Dias, Mathias Roberto Loch, Alberto Durán González, Selma Maffei de Andrade, Arthur Eumann Mesas
OBJECTIVE: To evaluate if perceived occupational factors are associated with insufficient free-time physical activity in Brazilian public school teachers. METHODS: The relationship between insufficient physical activity (< 150 minutes/week) and variables related to work was analyzed in 978 elementary and high school teachers calculating the prevalence ratio (PR) and 95% confidence interval (95%CI) in Poisson regression models, adjusted for sociodemographic and health variables...
July 20, 2017: Revista de Saúde Pública
https://www.readbyqxmd.com/read/28746557/occupational-burnout-syndrome-in-the-nursing-context-an-integrative-literature-review
#17
Mateus Estevam Medeiros-Costa, Regina Heloísa Maciel, Denise Pereira do Rêgo, Lucimar Lucas de Lima, Maria Eliziane Pinto da Silva, Julyana Gomes Freitas
OBJECTIVE: To characterize the scientific production on Burnout Syndrome in the Nursingcontext, systematizing the location where the studies were carried out, the related constructs, the employed methods and their main results. METHOD: An integrative review of the literature with a bibliometric approach of articles published in Portuguese, Spanish and English between 2005 and 2016. RESULTS: 106 articles wereincluded. Mostinvolvedprevalence, and were descriptive, quantitative studies performed in hospitals...
July 20, 2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28746414/when-habitat-matters-habitat-preferences-can-modulate-co-occurrence-patterns-of-similar-sympatric-species
#18
César Augusto Estevo, Mariana Baldy Nagy-Reis, James D Nichols
Disentangling the role of competition in regulating the distribution of sympatric species can be difficult because species can have different habitat preferences or time use that introduce non-random patterns that are not related to interspecific interactions. We adopted a multi-step approach to systematically incorporate habitat preferences while investigating the co-occurrence of two presumed competitors, morphologically similar, and closely related ground-dwelling birds: the brown tinamou (Crypturellus obsoletus) and the tataupa tinamou (C...
2017: PloS One
https://www.readbyqxmd.com/read/28746347/is-there-a-correlation-between-socioeconomic-disparity-and-functional-outcome-after-acute-ischemic-stroke
#19
Tian Song, Yuesong Pan, Ruoling Chen, Hao Li, Xingquan Zhao, Liping Liu, Chunxue Wang, Yilong Wang, Yongjun Wang
BACKGROUND: To investigate the impact of low socioeconomic status (SES), indicated by low level of education, occupation and income, on 3 months functional outcome after ischemic stroke. METHODS: We analyzed data from the China National Stroke Registry (CNSR), a multicenter and prospective registry of consecutive patients with acute cerebrovascular events occurred between September 2007 and August 2008. 11226 patients with ischemic stroke had SES and clinical characteristics data collected at baseline and mRS measured as indicator of functional outcome in 3 months follow up...
2017: PloS One
https://www.readbyqxmd.com/read/28746013/teaching-about-human-papillomavirus-lessons-learned
#20
Shannon Gayle Panther, Kimberly Caye McKeirnan, Julie Marie Akers
Occupational and environmental health nurses play a critical role in educating the public about human papillomavirus (HPV). With HPV vaccination rates remaining low, creative educational models should be explored.
August 2017: Workplace Health & Safety
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