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https://www.readbyqxmd.com/read/28449512/primary-tracheal-schwannoma-treated-by-surgical-resection-a-case-report
#1
Ding-Pei Han, Jie Xiang, Zhi-Qiu Ye, Dan-Nong He, Xiao-Chun Fei, Chao-Fu Wang, Jia-Ming Che, Jun-Biao Hang, He-Cheng Li
The rarity and non-specific symptoms of benign primary tracheal tumors always leaded to misdiagnosis and delayed treatment, and also undefined the optimal treatment. In this case, a 45-year-old woman had a history of progressive shortness of breath and dry cough for several years, CT scan revealed an intra-luminal tracheal mass invaded the left side of tracheal wall. After being located by bronchoscope preoperatively, the tumor was removed by surgical resection. The tumor was 1.5 cm in diameter with intact capsule...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449511/delayed-onset-tension-hemothorax-following-blunt-trauma-and-the-rupture-of-a-previously-undiagnosed-aberrant-right-subclavian-artery
#2
Alex Fourdrain, Sophie Lafitte, Jules Iquille, Florence De Dominicis, Pascal Berna
An arteria lusoria is a well-known anatomic variant of the right subclavian artery. We describe a patient in whom an arteria lusoria injury was revealed by delayed-onset tension hemothorax following blunt trauma to the thorax.
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28449429/pancreatic-lymphoepithelial-cysts-diagnosed-with-endosonography-guided-fine-needle-aspiration
#3
Youngmin Oh, Yonghyeok Choi, Seung Myoung Son, Jisun Lee, Yook Kim, Joung Ho Han, Seon Mee Park
Although lymphoepithelial cysts (LECs) of the pancreas are benign lesions, most of them have been treated with surgical resection due to diagnostic difficulty. We report a 66-year-old woman diagnosed with pancreatic LECs. Abdominal ultrasound revealed two masses in the pancreas, which were not visible on the abdominal computed tomography. In an abdominal magnetic resonance imaging, pancreas lesions showed solid tumors, which revealed a low signal intensity on T1-, moderate high signal intensity on T2 weighted images, and homogeneous delayed enhancement in the portal venous phase...
April 25, 2017: Korean Journal of Gastroenterology, Taehan Sohwagi Hakhoe Chi
https://www.readbyqxmd.com/read/28449405/the-impact-of-lesion-location-on-dysphagia-incidence-pattern-and-complications-in-acute-stroke-part-2-oropharyngeal-residue-swallow-and-cough-response-and-pneumonia
#4
S Suntrup-Krueger, A Kemmling, T Warnecke, C Hamacher, S Oelenberg, T Niederstadt, W Heindel, H Wiendl, R Dziewas
BACKGROUND AND PURPOSE: Dysphagia is a well-known complication of acute stroke. Given the complexity of cerebral swallowing control it is still difficult to predict which patients are likely to develop swallowing dysfunction based on their neuroimaging. In Part 2 of a comprehensive voxel-based imaging study, whether the location of a stroke lesion can be correlated with further dysfunctional swallowing patterns, pulmonary protective reflexes and pneumonia was evaluated. METHODS: In all, 200 acute stroke cases were investigated applying flexible endoscopic evaluation of swallowing within 96 h from admission...
April 27, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28449346/airborne-allergic-contact-dermatitis-caused-by-isothiazolinones-in-water-based-paints-a-retrospective-study-of-44-cases
#5
Emmanuelle Amsler, Olivier Aerts, Nadia Raison-Peyron, Michèle Debons, Brigitte Milpied, Françoise Giordano-Labadie, Julie Waton, Marie C Ferrier-Le Bouëdec, Isabelle Lartigau, Catherine Pecquet, Haudrey Assier, Martine Avenel-Audran, Claire Bernier, Florence Castelain, Evelyne Collet, Marie-Noëlle Crépy, Nathalie Genillier, Pascal Girardin, Pauline Pralong, Florence Tetart, Dominique Vital-Durand, Angele Soria, Annick Barbaud
BACKGROUND: Airborne allergic contact dermatitis caused by paints containing isothiazolinones has been recognized as a health hazard. OBJECTIVES: To collect epidemiological, clinical and patch test data on airborne allergic contact dermatitis caused by isothiazolinone-containing paints in France and Belgium. METHODS: A descriptive, retrospective study was initiated by the Dermatology and Allergy Group of the French Society of Dermatology, including methylchloroisothiazolinone (MCI)/methylisothiazolinone (MI)- and/or MI-sensitized patients who developed airborne allergic contact dermatitis following exposure to isothiazolinone-containing paint...
April 27, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28449212/predictors-of-success-of-external-cephalic-version-and-cephalic-presentation-at-birth-among-1-253-women-with-non-cephalic-presentation-using-logistic-regression-and-classification-tree-analyses
#6
Eileen K Hutton, Julia C Simioni, Lehana Thabane
INTRODUCTION: Among women with a fetus in non-cephalic presentation, external cephalic version (ECV) has been shown to reduce the rate of breech presentation at birth and cesarean birth. Compared to ECV at term, beginning ECV prior to 37 weeks gestation decreases the number of infants in a non-cephalic presentation at birth. The purpose of this secondary analysis was to investigate factors associated with a successful ECV procedure and to present this in a clinically useful format. MATERIAL AND METHODS: Data were collected as part of the Early ECV Pilot and Early ECV2 Trials, which randomised 1,776 women with a fetus in breech presentation to either early ECV (34 to 36 weeks gestation) or delayed ECV (at or after 37 weeks)...
April 27, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28449052/implementation-of-a-postoperative-outpatient-care-pathway-for-delayed-hyponatremia-following-transsphenoidal-surgery
#7
Michael A Bohl, Shahjehan Ahmad, William L White, Andrew S Little
BACKGROUND: After transsphenoidal surgery, delayed hyponatremia (DH) is the leading cause of 30-d unplanned hospital readmissions. OBJECTIVE: To determine the impact of a DH care pathway on 30-d readmissions after transsphenoidal surgery. METHODS: Data from before and after DH care pathway implementation were retrospectively reviewed. Patient demographics and clinical characteristics were compared. Readmission causes, clinical pathway failures, sodium trends, and symptoms were evaluated...
April 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28449044/vernakalant-does-not-alter-early-repolarization-or-contractility-in-normal-and-electrically-remodelled-atria
#8
Arne van Hunnik, Hussein Nasrallah, Dennis H Lau, Marion Kuiper, Sander Verheule, Ulrich Schotten
Aims: Besides the inhibition of the sodium inward current, vernakalant also inhibits the ultra rapid rectifier (IKur) and transient outward current (Ito). Inhibition of these currents increases contractility in canine atrial myocytes and goat atria. We investigated the effect of vernakalant on early repolarization and contractility in normal and electrically remodelled atria. Methods and results: Goats were implanted a pressure catheter, piezoelectric crystals, and electrodes to obtain atrial contractility and effective refractory period (ERP)...
April 25, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28449010/excess-of-a-rassf1-targeting-microrna-mir-193a-3p-perturbs-cell-division-fidelity
#9
Sofia Pruikkonen, Marko J Kallio
BACKGROUND: Several microRNA (miRNA) molecules have emerged as important post-transcriptional regulators of tumour suppressor and oncogene expression. Ras association domain family member 1 (RASSF1) is a critical tumour suppressor that controls multiple aspects of cell proliferation such as cell cycle, cell division and apoptosis. The expression of RASSF1 is lost in a variety of cancers due to the promoter hypermethylation. METHODS: miR-193a-3p was identified as a RASSF1-targeting miRNA by a dual screening approach...
April 27, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28448988/anaemia-following-artemisinin-based-combination-treatments-of-uncomplicated-plasmodium-falciparum-malaria-in-children-temporal-patterns-of-haematocrit-and-the-use-of-uncomplicated-hyperparasitaemia-as-a-model-for-evaluating-late-appearing-anaemia
#10
Akin Sowunmi, Kazeem Akano, Godwin Ntadom, Adejumoke Ayede, Stephen Oguche, Chimere Agomo, Henrietta Okafor, Ismaila Watila, Martin Meremikwu, William Ogala, Philip Agomo, Elsie Adowoye, Bayo Fatunmbi, Temitope Aderoyeje, Christian Happi, Grace Gbotosho, Onikepe Folarin
BACKGROUND: In severe malaria, intravenous artesunate may cause delayed haemolytic anaemia but there has been little evaluation of the propensity of oral artemisinin-based combination treatments (ACTs) to cause late-appearing anaemia. METHODS: The frequency of anaemia (haematocrit <30%), and temporal changes in haematocrit were evaluated in 1,191 malarious children following ACTs. "Haematocrit conservation" was evaluated by using the fall in haematocrit/1,000 asexual parasites cleared from the peripheral blood (FIH/1,000 asexual parasites cpb), and the ratio of the average haematocrit (on the first 3 days of starting treatment):total parasitaemia cleared...
April 28, 2017: Chemotherapy
https://www.readbyqxmd.com/read/28448965/neuroprotective-treatments-after-perinatal-hypoxic-ischemic-brain-injury-evaluated-with-magnetic-resonance-spectroscopy
#11
Hester Rijkje Berger, Eva Brekke, Marius Widerøe, Tora Sund Morken
Perinatal hypoxic-ischemic brain injury is a major health problem. Adjuvant treatments that improve the neuroprotective effect of the current treatment, therapeutic hypothermia, are urgently needed. The growing knowledge about the complex pathophysiology of hypoxia-ischemia (HI) has led to the discovery of several important targets for neuroprotection. Early interventions should focus on the preservation of energy metabolism, the reduction of glutamate excitotoxicity and oxidative stress, the maintenance of calcium homeostasis, and the prevention of apoptosis...
April 28, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28448920/the-effect-of-equiaxial-stretching-on-the-osteogenic-differentiation-and-mechanical-properties-of-human-adipose-stem-cells
#12
Sanni Virjula, Feihu Zhao, Joni Leivo, Sari Vanhatupa, Joose Kreutzer, Ted J Vaughan, Anna-Maija Honkala, Marlitt Viehrig, Conleth A Mullen, Pasi Kallio, Laoise M McNamara, Susanna Miettinen
Although mechanical cues are known to affect stem cell fate and mechanobiology, the significance of such stimuli on the osteogenic differentiation of human adipose stem cells (hASCs) remains unclear. In this study, we investigated the effect of long-term mechanical stimulation on the attachment, osteogenic differentiation and mechanical properties of hASCs. Tailor-made, pneumatic cell stretching devices were used to expose hASCs to cyclic equiaxial stretching in osteogenic medium. Cell attachment and focal adhesions were visualised using immunocytochemical vinculin staining on days 3 and 6, and the proliferation and alkaline phosphatase activity, as a sign of early osteogenic differentiation, were analysed on days 0, 6 and 10...
April 13, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28448908/biological-impacts-of-glyphosate-on-morphology-embryo-biomechanics-and-larval-behavior-in-zebrafish-danio-rerio
#13
Shuhui Zhang, Jia Xu, Xiangyu Kuang, Shibao Li, Xiang Li, Dongyan Chen, Xin Zhao, Xizeng Feng
All of these days, residues of herbicides such as glyphosate are widely distributed in the environment. The ubiquitous use of glyphosate has drawn extensive attention to its toxicity as an organic pollutant. In this study, we employed larval zebrafish as an animal model to evaluate the effect of different concentrations of glyphosate on early development via morphological, biomechanics, behavioral and physiological analyses. Morphological results showed that an obvious delay occurred in the epiboly process and body length, eye and head area were reduced at concentrations higher than 10 mg/L...
April 21, 2017: Chemosphere
https://www.readbyqxmd.com/read/28448864/new-agents-for-endocrine-resistance-in-breast-cancer
#14
REVIEW
Christian Maurer, Samuel Martel, Dimitrios Zardavas, Michail Ignatiadis
Estrogen receptor positive (ER+) and HER2-negative (HER2-) breast cancer (BC) is the most common BC subtype, defined by expression of the ER and absence of HER2 amplification. Endocrine treatment (ET), aiming at therapeutic blockade of ER signaling, represents the therapeutic mainstay for patients with both early and advanced disease. Despite its wide therapeutic efficacy, ET fails for a proportion of ER+, HER2- BC patients with early disease who develop endocrine resistance, resulting in disease recurrence...
April 24, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28448821/the-implications-of-war-captivity-and-long-term-psychopathology-trajectories-for-telomere-length
#15
Zahava Solomon, Noga Tsur, Yafit Levin, Orit Uziel, Meir Lahav, Avi Ohry
BACKGROUND: Previous findings have demonstrated the link between trauma, its psychopathological aftermath and cellular aging, as reflected in telomere length. However, as long-term examinations of psychopathology following trauma are scarce, very little is known regarding the repercussions of depression and PTSD trajectories of psychopathology for telomeres. The current study examined the implications of war captivity and depression/PTSD trajectories on telomere length. METHODS: Ninety-nine former prisoners of war (ex-POWs) from the 1973 Yom Kippur War were evaluated for depression and PTSD at 18, 30, 35 and 42 years after the war...
April 12, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28448800/assessment-of-bilingual-children-what-if-testing-both-languages-is-not-possible
#16
Tessel Boerma, Elma Blom
Language delays of bilingual children can arise from language impairment (LI) but also from insufficient exposure to the target language. A reliable diagnosis of LI in bilingual children is therefore ideally based on the evaluation of both languages, as LI affects each language that is learned. However, due to the multitude of language combinations that are encountered in clinical practice, this is often not feasible. Bilingual norm-referencing may offer a solution, but the heterogeneity within the bilingual population makes it difficult to determine appropriate standards for every child...
April 10, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28448695/long-term-memory-in-older-children-adolescents-and-adults-with-autism-spectrum-disorder
#17
Diane L Williams, Nancy J Minshew, Gerald Goldstein, Carla A Mazefsky
This study extends prior memory reports in autism spectrum disorders (ASD) by investigating memory for narratives after longer recall periods and by examining developmental aspects of narrative memory using a cross-sectional design. Forty-seven older children/adolescents with ASD and 31 youth with typical development (TD) and 39 adults with ASD and 45 TD adults were compared on memory for stories from standardized measures appropriate for each age group at three intervals (immediate, 30 min, and 2 day). Both the youth with and without ASD had difficulty with memory for story details with increasing time intervals...
April 27, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28448668/prognostic-indication-of-sarcopenia-for-wound-complication-after-total-laryngectomy
#18
Virginie Achim, Jasper Bash, Alia Mowery, Alexander R Guimaraes, Ryan Li, Josh Schindler, Mark Wax, Peter Andersen, Daniel Clayburgh
Importance: Postoperative wound complications after total laryngectomy (TL) increase hospital stay, costs, and delay adjuvant therapy when indicated. Recently, sarcopenia has been identified as a predictor of postoperative complications in patients undergoing major surgery but has not been assessed in head and neck surgery patients. Objective: To determine the incidence of sarcopenia in patients with squamous cell carcinoma (SCC) undergoing TL and evaluate its association with the development of postoperative wound complications...
April 27, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28448624/overexpression-of-the-protein-phosphatase-2a-regulatory-subunit-a-gene-zmpp2aa1-improves-low-phosphate-tolerance-by-remodeling-the-root-system-architecture-of-maize
#19
Jiemin Wang, Laming Pei, Zhe Jin, Kewei Zhang, Juren Zhang
Phosphate (Pi) limitation is a constraint for plant growth and development in many natural and agricultural ecosystems. In this study, a gene encoding Zea mays L. protein phosphatase 2A regulatory subunit A, designated ZmPP2AA1, was induced in roots by low Pi availability. The function of the ZmPP2AA1 gene in maize was analyzed using overexpression and RNA interference. ZmPP2AA1 modulated root gravitropism, negatively regulated primary root (PR) growth, and stimulated the development of lateral roots (LRs)...
2017: PloS One
https://www.readbyqxmd.com/read/28448571/localization-of-adenovirus-morphogenesis-players-together-with-visualization-of-assembly-intermediates-and-failed-products-favor-a-model-where-assembly-and-packaging-occur-concurrently-at-the-periphery-of-the-replication-center
#20
Gabriela N Condezo, Carmen San Martín
Adenovirus (AdV) morphogenesis is a complex process, many aspects of which remain unclear. In particular, it is not settled where in the nucleus assembly and packaging occur, and whether these processes occur in a sequential or a concerted manner. Here we use immunofluorescence and immunoelectron microscopy (immunoEM) to trace packaging factors and structural proteins at late times post infection by either wildtype virus or a delayed packaging mutant. We show that representatives of all assembly factors are present in the previously recognized peripheral replicative zone, which therefore is the AdV assembly factory...
April 2017: PLoS Pathogens
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