Yong-Jing Tang, Jian Zhang, Jie Wang, Ren-Dong Tian, Wei-Wei Zhong, Ben-Sheng Yao, Bing-Yu Hou, Ying-Hua Chen, Wei He, Yi-Huai He
BACKGROUND: Genetic factors of chronic intestinal ulcers are increasingly garnering attention. We present a case of chronic intestinal ulcers and bleeding associated with mutations of the activin A receptor type II-like 1 ( ACVRL1 ) and phospholipase A2 group IVA ( PLA2G4A ) genes and review the available relevant literature. CASE SUMMARY: A 20-year-old man was admitted to our center with a 6-year history of recurrent abdominal pain, diarrhea, and dark stools. At the onset 6 years ago, the patient had received treatment at a local hospital for abdominal pain persisting for 7 d, under the diagnosis of diffuse peritonitis, acute gangrenous appendicitis with perforation, adhesive intestinal obstruction, and pelvic abscess...
March 27, 2024: World Journal of Gastrointestinal Surgery