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https://www.readbyqxmd.com/read/28746018/splenic-abscess-in-immunocompetent-patients-managed-primarily-without-splenectomy-a-series-of-7-cases
#1
S Divyashree, Nikhil Gupta
INTRODUCTION: Splenic abscesses are rare in immunocompetent adults. Despite advances in diagnosis and treatment, these abscesses are still potentially life threatening. Various factors have been reported to predispose otherwise immunocompetent adults to splenic abscesses. Splenectomy was once considered the "gold standard" treatment. However, the trend is shifting to a conservative approach. CASE DESCRIPTION: We describe seven cases of splenic abscess in immunocompetent adults, the cause of which ranged from tuberculosis to salmonella and was as rare as Plasmodium vivax...
2017: Permanente Journal
https://www.readbyqxmd.com/read/28740350/cryptogenic-multifocal-ulcerous-stenosing-enteritis-radiologic-features-and-clinical-behavior
#2
Jiyoung Hwang, Jin Sil Kim, Ah Young Kim, Joon Seok Lim, Se Hyung Kim, Min Ju Kim, Mi Sung Kim, Kyoung Doo Song, Ji Young Woo
AIM: To investigate the characteristic radiologic findings of cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) which can be differentiated from other similar bowel disease and to assess their clinical behavior. METHODS: Twenty pathologically and clinically confirmed CMUSE patients (males:females = 8:12; mean age: 40.4 years) between March 2002 and August 2015 from seven academic centers in South Korea were retrospectively reviewed. We evaluated small bowel series (SBS; n = 25), computed tomography (CT) enterography (n = 21), magnetic resonance (MR) enterography (n = 2), and abdominopelvic CT (n = 18) images, focusing on enteric and perienteric manifestations...
July 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28739797/unraveling-drug-penetration-of-echinocandin-antifungals-at-the-site-of-infection-in-an-intra-abdominal-abscess-model
#3
Yanan Zhao, Brendan Prideaux, Yoji Nagasaki, Min Hee Lee, Pei-Yu Chen, Landry Blanc, Hsinpin Ho, Cornelius J Clancy, Minh Hong Nguyen, Véronique Dartois, David S Perlin
Intra-abdominal candidiasis (IAC) is a prominent invasive fungal infection associated with high mortality. Prompt antifungal therapy and source control are crucial for successful treatment. Echinocandin antifungal drugs are first-line agents. Yet, their clinical effectiveness is highly variable with known potential for breakthrough resistance, and little is known about drug exposure at the site of infection. Using matrix-assisted desorption/ionization mass spectrometry imaging technology, we investigated the spatial and quantitative distribution in tissue lesions for two echinocandin drugs, micafungin and CD101, in a clinically relevant IAC mouse model...
July 24, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28738237/a-case-report-of-unexpected-pathology-within-an-incarcerated-ventral-hernia
#4
Erica D Kane, Katharine R Bittner, Michelle Bennett, John R Romanelli, Neal E Seymour, Jacqueline J Wu
INTRODUCTION: Incidence of hernial appendicitis is 0.008%, most frequently within inguinal and femoral hernias. Up to 2.5% of appendectomy patients are found to have Crohn's disease. Elucidating the etiology of inflammation is essential for directing management. PRESENTATION OF CASE: A 51-year-old female with achondroplastic dwarfism, multiple cesarean sections, and subsequent massive incisional hernia, presented with ruptured appendicitis within her incarcerated hernia...
July 8, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28737147/brucella-causing-liver-abscess-in-a-child-with-selective-iga-deficiency
#5
Devdeep Mukherjee, Priyankar Pal, Ritabrata Kundu
BACKGROUND: Brucella has been known to cause pyrexia of unknown origin. CASE CHARACTERISTICS: 9-year-old boy with fever and abdominal pain; multiple abscesses within the liver on ultrasonography. OBSERVATIONS: IgM Antibodies against Brucella were raised in his serum sample, and Brucella serum agglutination test was positive. Immunological work-up suggested selective IgA deficiency. Reduction in size following treatment with trimethoprim-sulphamethoxazole, amikacin and doxycycline...
July 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/28736222/hypermucoviscosity-rmpa-and-aerobactin-are-associated-with-community-acquired-klebsiella-pneumoniae-bacteremic-isolates-causing-liver-abscess-in-singapore
#6
Thean Yen Tan, Melissa Ong, Yvonne Cheng, Lily Siew Yong Ng
INTRODUCTION: This retrospective study investigated the clinical etiology of community-acquired bacteremic Klebsiellapneumoniae infections, and characterized laboratory and genetic markers which may be associated with primary liver abscess (PLA). METHODS: Community-onset K. pneumoniae bacteremic episodes from 2010 to 2011 were identified from the laboratory information system. Isolates were retrieved for susceptibility testing, hypermucoviscosity testing, PCR-based serotyping (K1, K2 and K5) and PCR detection of virulence genes (rmpA, alls, kfu and aerobactin)...
July 14, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28735117/pubic-osteomyelitis-after-surgery-for-perforated-colonic-diverticulitis-with-fecal-peritonitis-a-case-report
#7
Daichi Kitaguchi, Tsuyoshi Enomoto, Yusuke Ohara, Tatsuya Oda, Nobuhiro Ohkohchi
INTRODUCTION: Pubic osteomyelitis is a rare type of suppurative osteomyelitis. Early diagnosis of pubic osteomyelitis is difficult, and prolonged inflammation results in progressive bone degradation, severe pelvic pain and a wide-based gait. PRESENTATION OF CASE: We report the case of an 82-year-old woman who was admitted to a previous hospital with severe abdominal pain caused by a perforated colonic diverticulum with fecal peritonitis. She underwent an emergency operation and a postoperative wound infection occurred...
July 13, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28732747/shorter-overall-operative-time-when-barbed-suture-is-used-in-primary-laparoscopic-gastric-bypass-a-cohort-study-of-25-006-cases
#8
Bjarni Vidarsson, Magnus Sundbom, David Edholm
BACKGROUND: Closing the remaining opening in a linear stapled anastomosis, for example in laparoscopic Roux-en-Y gastric bypass (LRYGB), can be challenging. OBJECTIVES: To evaluate if the novel unidirectional barbed suture (BS) is of value in LRYGB compared with polyfilament (PS) suture. We have compared operative time, early complications, and length of stay, as well as anastomotic strictures and small bowel obstruction during the first year. SETTING: Retrospective study from the Scandinavian Obesity Surgery Registry (SOReg)...
April 25, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28723465/case-presentation-mycotic-aortic-aneurysm-and-psoas-abscess-as-a-complication-of-bacillus-calmette-gu%C3%A3-rin-instillations
#9
R Jeroen A van Moorselaar, Willem Wisselink
To prevent life-threatening aortic ruptures, it is important that primary care physicians and urologists are aware of the symptoms of a mycotic abdominal aortic aneurysm, even several months or years after bacillus Calmette-Guérin therapy.
October 2016: European Urology Focus
https://www.readbyqxmd.com/read/28722597/occult-amoebic-liver-abscess-as-cause-of-extensive-inferior-vena-cava-and-hepatic-vein-thrombosis
#10
Leslie Martin, Nishigandha Burute, Ehsan Haider, Pablo E Serrano, Timothy O'Shea, Deborah Siegal
The most common extraintestinal complication of Entamoeba histolytica is amoebic liver abscess (ALA). Hepatic vein and inferior vena cava (IVC) thrombosis are rare but well-documented complications of ALA, typically attributed to mechanical compression and inflammation associated with a large abscess. We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. He was found to have thrombophlebitis of the IVC, accessory right hepatic vein, and bilateral iliac veins...
July 3, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28720750/tuberculous-psoas-abscess-and-worsening-vascular-aneurysm-all-from-bacillus-calmette-guerin-bcg-therapy
#11
Emmanuel Okon, Janelle Stearns, Arun Kumar Durgam
BACKGROUND Intravesical bacillus Calmette-Guerin (BCG) is used in the treatment and prophylaxis of carcinoma in situ of the urinary bladder and for the prophylaxis of primary or recurrent stage Ta and T1 papillary tumors following transurethral resection. Significant systemic complications are rare but have been reported. CASE REPORT We describe this case of Mycobacterium bovis psoas abscess and worsening abdominal aortic aneurysm following BCG therapy for bladder cancer. A 76-year-old male presented with a fever of a few days...
July 19, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28719956/a-case-of-ectopic-peritoneal-paragonimiasis-mimicking-diverticulitis-or-abdominal-abscess
#12
Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Yong Sik Yoon, Kyung Won Kim, Jaeeun Cho, Jong-Yil Chai, Yong Pil Chong
Paragonimiasis is a parasitic disease caused by Paragnonimus species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with Paragonimus westermani, which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other inflammatory diseases...
June 2017: Korean Journal of Parasitology
https://www.readbyqxmd.com/read/28717908/systematic-review-and-meta-analysis-of-laparoscopic-versus-open-appendicectomy-in-adults-with-complicated-appendicitis-an-update-of-the-literature
#13
Christos Athanasiou, Sonia Lockwood, Georgios A Markides
AIMS: To review and compare the outcomes of laparoscopic (LA) versus open appendicectomy (OA) in complicated appendicitis in adult patients, eight years after the last literature review. METHODS: The PRISMA guidelines were adhered to. Pre-defined inclusion and exclusion criteria were used to search the PubMed, Scopus and Cochrane databases and extract relevant data. Methodological and quality assessment was undertaken with outcome meta-analysis and subgroup analyses of methodological quality, type of study and year of study...
July 17, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28710233/venobiliary-fistula-with-haemobilia-a-rare-complication-of-percutaneous-liver-biopsy
#14
Rotimi Ayoola, Parth Jamindar, Renee Williams
We describe a case of a 36-year-old man with a history of chronic hepatitis C who presented with abdominal pain 3 days after undergoing a percutaneous ultrasound-guided liver biopsy. Initial investigations revealed a venobiliary fistula with haemobilia and obstructive jaundice with direct bilirubin peaking at 9.2 mg/dL. He underwent an endoscopic retrograde cholangiopancreatography with sphincterotomy and stent placement, bilirubin decreased to 3.7 mg/dL, and the patient was discharged. The patient returned with recurrent abdominal pain and upper gastrointestinal bleeding with haemoglobin of 8...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28710193/ciliated-foregut-cyst-of-the-gall-bladder-the-largest-ever-described
#15
Alexia Farrugia, Ivan Blazic, Predrag Andrejevic
A 78-year-old man presented to the accident and emergency department with acute abdominal pain. A CT scan done to investigate the pain showed an intra-abdominal abscess medial to the caecum and an incidental exophytic lesion in the gall bladder. This was excised during surgery and sent for histological examination. Histology showed a ciliated foregut cyst of the gall bladder. A literature review revealed that this was the 13th case worldwide, as ciliated foregut cysts are usually found either above the diaphragm or in the liver...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28709494/multiple-abdominal-abscesses-a-not-so-common-presentation-of-ntm
#16
Darshan K Bajaj, R A S Kushwaha, Anand Srivastava, Mona Asnani
Non-tuberculous Mycobacteria/Mycobacterium other than tuberculosis (MOTT) are ubiquitous organisms. They are acid fast bacilli often giving trouble to the physician to distinguish it from Mycobacterium tuberculosis. These organisms are a menace for the treating physician as when to treat and when not to treat. They are often difficult to diagnose and may present in a variety of forms with propensity to cause number of infections of different body parts and organs. They are more common in immunocompromised individuals e...
July 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28706890/clinical-implication-of-discrepancies-between-surgical-and-pathologic-diagnoses-of-acute-appendicitis
#17
Jinbeom Cho, Dosang Lee, Kiyoung Sung, Jongmin Baek, Junhyun Lee
PURPOSE: The postoperative treatment after appendectomy is usually decided on the basis of the surgeons' intraoperative findings. Comparatively, the pathologic diagnosis of appendicitis is confirmed several days after the surgery; therefore, it usually does not affect the postoperative treatment strategy. The aim of this study was to investigate the discrepancies between the surgical and pathologic diagnoses of appendicitis and to identify their clinical implication. METHODS: A retrospective observational study was performed in 1,817 patients who underwent 3-port laparoscopic appendectomy for the final diagnosis of appendicitis...
July 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28702189/a-case-report-of-pneumo-retro-peritoneum-an-unusual-presentation-of-ischio-rectal-abscess
#18
Usman Ismat Butt, Samiullah Bhatti, Abdul Wadood, Usman Ali Rehman, Shabbar Hussain Changazi, Kashif Malik, Shah Fahad, Anila Chughtai, Nauman Arif Jadoon, Mahmood Ayyaz
INTRODUCTION: Ano-rectal abscesses are common. They however usually do not present with abdominal symptoms. CT although useful is not routinely carried out. Finding of Pneumo-retro-peritoneum with ischio-rectal abscess is rare. CASE PRESENTATION: We present the case of a diabetic gentleman who presented with abdominal pain and distension and was found to have ischio-rectal abscess on perianal examination. Although initially suspected to have acute abdomen due to perforated viscus, CT scan revealed pneumo-retro-peritoneum which appeared to arise due to the abscess...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28702149/postoperative-antibiotic-therapy-after-appendectomy-in-patients-with-non-perforated-appendicitis
#19
Seyed-Mohammadreza Sadraei-Moosavi, Novin Nikhbakhsh, Ali-Asghar Darzi
BACKGROUND: Appendectomy intra-abdominal is the most frequently performed emergency surgery. This study was conducted to determine the role of postoperative antibiotics in reducing surgical site infections (SSIs) and abscess formation after open appendectomy. METHODS: In the Department of Surgery, Shahid Beheshti Hospital, Babol, Iran, from October 2013 to October 2014 one hundred and fifty two patients, who underwent appendectomy for nonperforated appendicitis (NPA) and fulfilled the selection criteria, were randomized into two groups...
2017: Caspian Journal of Internal Medicine
https://www.readbyqxmd.com/read/28693916/phosphonodifluoropyruvate-is-a-mechanism-based-inhibitor-of-phosphonopyruvate-decarboxylase-from-bacteroides-fragilis
#20
Katharina Pallitsch, Megan P Rogers, Forest H Andrews, Friedrich Hammerschmidt, Michael J McLeish
Bacteroides fragilis, a human pathogen, helps in the formation of intra-abdominal abscesses and is involved in 90% of anaerobic peritoneal infections. Phosphonopyruvate decarboxylase (PnPDC), a thiamin diphosphate (ThDP)-dependent enzyme, plays a key role in the formation of 2-aminoethylphosphonate, a component of the cell wall of B. fragilis. As such PnPDC is a possible target for therapeutic intervention in this, and other phosphonate producing organisms. However, the enzyme is of more general interest as it appears to be an evolutionary forerunner to the decarboxylase family of ThDP-dependent enzymes...
June 13, 2017: Bioorganic & Medicinal Chemistry
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