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heart cryoablation

Florian Hintringer
BACKGROUND: Atrial fibrillation (AF) affects 1-2% of the population, and its prevalence is estimated to at least double in the next 50 years as the population ages. AREAS OF AGREEMENT: AF results in impaired quality of life and even increased mortality. Drugs frequently fail to stabilize sinus rhythm. AREAS OF CONTROVERSY: Catheter ablation is a valuable treatment alternative, even as a first-line therapy in selected cases. However, catheter ablation of AF is challenging, even for experienced operators...
October 26, 2016: British Medical Bulletin
Patricia E Thomas, Scott L Macicek
BACKGROUND: Catheter ablation has been used to manage supraventricular arrhythmia in children since 1990. This article reviews the history of catheter ablation used to treat arrhythmia in children and discusses new frontiers in the field. We also address ablation in adult patients with a history of congenital heart disease (CHD) that was diagnosed and initially treated in childhood. METHODS: We conducted an evidence-based literature review to gather available data on ablation for supraventricular tachycardia in children and adult patients with CHD...
2016: Ochsner Journal
Paramdeep S Dhillon, Giulia Domenichini, Hanney Gonna, Anthony Li, Nadia Sunni, Michael Mahmoudi, Mark M Gallagher
BACKGROUND: Arrhythmias originating from the right ventricular outflow tract are generally considered benign but cases of cardiac arrest have been described, usually associated with polymorphic ventricular tachycardia or extrasystoles with short coupling intervals. CASE PRESENTATION: We report the case of a 54-year-old Caucasian woman with symptomatic right ventricular outflow tract arrhythmias without structural heart disease who suffered a ventricular fibrillation arrest without prior malignant clinical features...
2016: Journal of Medical Case Reports
Giacomo Mugnai, Darragh Moran, Erwin Ströker, Diego Ruggiero, Hugo Enrique Coutino-Moreno, Ken Takarada, Valentina De Regibus, Rajin Choudhury, Saverio Iacopino, Pasquale Filannino, Vincent Umbrain, Stefan Beckers, Pedro Brugada, Carlo de Asmundis, Gian-Battista Chierchia
PURPOSE: Our aim was to analyse the temperature behaviour during second-generation cryoballoon ablation (CB-A) in patients with ongoing atrial fibrillation (AF) compared with those in sinus rhythm (SR). METHODS: Consecutive patients with drug-resistant AF who underwent pulmonary vein (PV) isolation by CB-A from April 2014 to May 2015 were analysed. The exclusion criteria were any contraindication for the procedure including the presence of an intracavitary thrombus, uncontrolled heart failure, contraindications to general anaesthesia and cardioversion to SR during the ablation procedure...
December 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
Saurabh Kumar, Alexander F A Androulakis, Jean-Marc Sellal, Philippe Maury, Estelle Gandjbakhch, Xavier Waintraub, Anne Rollin, Pascale Richard, Philippe Charron, Samuel H Baldinger, Ciorsti J Macintyre, Bruce A Koplan, Roy M John, Gregory F Michaud, Katja Zeppenfeld, Frederic Sacher, Neal K Lakdawala, William G Stevenson, Usha B Tedrow
BACKGROUND: Lamin A/C (LMNA) cardiomyopathy is a genetic disease with a proclivity for ventricular arrhythmias. We describe the multicenter experience with percutaneous catheter ablation of sustained monomorphic ventricular tachycardia (VT) in LMNA cardiomyopathy. METHODS AND RESULTS: Twenty-five consecutive LMNA mutation patients from 4 centers were included (mean age, 55±9 years; ejection fraction, 34±12%; VT storm in 36%). Complete atrioventricular block was present in 11 patients; 3 patients were on mechanical circulatory support for severe heart failure...
August 2016: Circulation. Arrhythmia and Electrophysiology
Yasunori Kushiyama, Haruo Honjo, Ryoko Niwa, Hiroki Takanari, Masatoshi Yamazaki, Yoshio Takemoto, Ichiro Sakuma, Itsuo Kodama, Kaichiro Kamiya
It has been reported that blockade of the inward rectifier K(+) current (IK1) facilitates termination of ventricular fibrillation. We hypothesized that partial IK1 blockade destabilizes spiral wave (SW) re-entry, leading to its termination. Optical action potential (AP) signals were recorded from left ventricles of Langendorff-perfused rabbit hearts with endocardial cryoablation. The dynamics of SW re-entry were analyzed during ventricular tachycardia (VT), induced by cross-field stimulation. Intercellular electrical coupling in the myocardial tissue was evaluated by the space constant...
September 1, 2016: American Journal of Physiology. Heart and Circulatory Physiology
Kosuke Ujihira, Akira Yamada, Naritomo Nishioka, Yutaka Iba, Ryushi Maruyama, Katsuhiko Nakanishi, Ai Shimizu, Kanako C Hatanaka, Tomoko Mitsuhashi, Toshiya Shinohara, Hatsue Ishibashi Ueda
BACKGROUND: Primary cardiac sarcomas are extremely rare. Furthermore, the myxofibrosarcomas are one of the rarest forms of cardiac sarcomas, and its prognosis is known to be quite poor. CASE PRESENTATION: This is a case of a 23-year-old man who presented with acute severe congestive heart failure caused by almost complete obstruction of the mitral valve due to a large left atrial tumor. The patient required endotracheal intubation before his arrival to the hospital, and underwent an emergent surgical excision of the tumor...
2016: Journal of Cardiothoracic Surgery
Gabriella Boano, Meriam Åström Aneq, Jennie Kemppi, Farkas Vánky
OBJECTIVE: The indications for and the risk and benefit of concomitant surgical ablation for atrial fibrillation (AF) have not been fully delineated. Our aim was to survey whether the Cox-maze IV procedure is associated with postoperative heart failure (PHF) or other adverse short-term outcomes after mitral valve surgery (MVS). DESIGN: Consecutive patients with AF undergoing MVS with (n = 50) or without (n = 66) concomitant Cox-maze IV cryoablation were analysed regarding perioperative data and one-year mortality...
June 16, 2016: Scandinavian Cardiovascular Journal: SCJ
Fumiaki Kimura, Sentarou Nakanishi, Hiroyuki Kamiya
A 61-year-old man presented with lower leg edema, left-sided parasternal systolic heart murmur, and electrocardiographic abnormalities. Transthoracic echocardiography revealed myocardial hypertrophy and severe obstruction of the outflow tract of the right ventricle (RV) with a gradient of 134 mmHg. Cardiac catheterization confirmed the presence of double chambered right ventricle, with a pressure gradient of 84 mmHg between RV inlet and outlet. Chest computed tomography showed his aortic root enlarged to 55 mm...
May 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
Xiaobing Li, Limimg Liu, Long Song, Cheng Luo, Benli Yang, Yuhong Liu
OBJECTIVE: To summarize the clinical data of patients who experienced cryoablation in minimally invasive mitral valve surgery and to explore safety and effectiveness of the surgery.
 METHODS: We retrospectively collected the clinical data of patients who experienced cryoablation in minimally invasive mitral valve surgery in Department of Cardiovascular of Second Xiangya Hospital from August 2013 to July 2015. Through a right side (4-6 cm) thoracotomy, femoral cannulation and aortic cross-clamp by Chitwood clamper was performed, left atrium was entered from interatrial groove...
March 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Kadri Murat Gurses, Duygu Kocyigit, Muhammed Ulvi Yalcin, Hande Canpinar, Hikmet Yorgun, Mehmet Levent Sahiner, Ergun Baris Kaya, Mehmet Ali Oto, Necla Ozer, Dicle Guc, Kudret Aytemir
Atrial fibrillation (AF) is the most common sustained arrhythmia. Inflammation has been suggested to play a vital role in the pathogenesis. Previous studies have investigated expression of inflammatory markers in AF. Several studies have focused on the effects of toll-like receptors (TLRs) on heart in terms of capability of modulating inflammation. In this study, we aimed to investigate whether peripheral monocyte TLR expression was associated with the AF presence, and recurrence of AF after cryoablation, as a reflection of inflammatory status...
May 1, 2016: American Journal of Cardiology
Shailendra Upadhyay, Anne Marie Valente, John K Triedman, Edward P Walsh
BACKGROUND: Variability in atrioventricular (AV) node location in congenital heart disease (CHD) can make catheter ablation for atrioventricular nodal reentrant tachycardia (AVNRT) challenging. OBJECTIVE: The purpose of this study was to describe institutional technique and outcomes for slow pathway modification in a cohort with CHD. METHODS: The study consisted of a retrospective review of CHD patients who underwent study from 2001 to 2013 with a diagnosis of AVNRT...
June 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Ahyeon Koh, Sarah R Gutbrod, Jason D Meyers, Chaofeng Lu, Richard Chad Webb, Gunchul Shin, Yuhang Li, Seung-Kyun Kang, Yonggang Huang, Igor R Efimov, John A Rogers
Knowledge of the distributions of temperature in cardiac tissue during and after ablation is important in advancing a basic understanding of this process, and for improving its efficacy in treating arrhythmias. Technologies that enable real-time temperature detection and thermal characterization in the transmural direction can help to predict the depths and sizes of lesion that form. Herein, materials and designs for an injectable device platform that supports precision sensors of temperature and thermal transport properties distributed along the length of an ultrathin and flexible needle-type polymer substrate are introduced...
February 4, 2016: Advanced Healthcare Materials
Javier Gualis, Mario Castaño, Jose Manuel Martínez-Comendador, Jose Miguel Marcos, Carlos Martín, Rodrigo Estévez-Loureiro, Jesús Gómez-Plana, Elio Martín, Javier Otero
UNLABELLED: The long-term results of cryomaze in patients with longstanding persistent atrial fibrillation during concomitant surgical procedures are still uncertain. METHODS: Between 2006 and 2011, 150 consecutive patients with associated long-lasting permanent atrial fibrillation and associated heart disease underwent heart surgery were treated by biatrial Cox-Maze (63 patients) or by isolated endocardial or epicardial left atrial cryoablation (83 patients) concomitantly...
April 2016: Archivos de Cardiología de México
Efstratios I Charitos, Paul D Ziegler, Ulrich Stierle, Bernhard Graf, Hans-Hinrich Sievers, Thorsten Hanke
OBJECTIVES: Surgical ablation for atrial fibrillation (AF) is an established therapy for the treatment of concomitant AF in cardiac surgery patients. We aim to present our prospective experience with 99 continuously monitored patients and investigate whether enhanced monitoring can identify patterns and factors influencing AF recurrence after surgical AF ablation. METHODS: Ninety-nine patients (73 males; age: 68.0 ± 9.2 years) with documented preoperative AF (paroxysmal: 29; persistent: 18; long-lasting persistent: 52, mean preoperative duration: 46 ± 53 months) underwent concomitant biatrial surgical ablation (Cox Maze III: 29), full set left atrial cryoablation (n = 22), high-intensity focused ultrasound (HIFU) box lesion (n = 46) or right-sided ablation (n = 2)...
December 2015: Interactive Cardiovascular and Thoracic Surgery
Charitha D Reddy, Michael J Silka, Yaniv Bar-Cohen
BACKGROUND: Atrioventricular nodal reentrant tachycardia (AVNRT) typically occurs in adolescents and adults with limited data regarding AVNRT in young children. METHODS: All patients with AVNRT who underwent electrophysiology study and ablation between 2005 and 2012 were retrospectively studied. Patients were stratified by age <10 years (young AVNRT) or ≥10 years (older AVNRT). Young AVNRT patients were also compared to age-matched patients with orthodromic reentrant tachycardia (ORT)...
November 2015: Pacing and Clinical Electrophysiology: PACE
Martin Eisenberger, Alan Bulava, Ales Mokracek, Jiri Hanis, Vojtech Kurfirst, Ladislav Dusek
BACKGROUND: The aim of the study was to evaluate whether the sequential hybrid approach combining surgical CryoMaze followed by the radiofrequency (RF) catheter ablation can improve freedom from atrial arrhythmias. METHODS: Thirty-five patients with persistent atrial fibrillation underwent a CryoMaze procedure in conjunction with cardiac surgery for structural heart disease. Three months after surgery, all patients underwent a 7-day electrocardiogram Holter followed by an electrophysiological study and mapping of the left and right atria...
December 2015: Pacing and Clinical Electrophysiology: PACE
Dennis Yang, Mary K Reinhard, Mihir S Wagh
AIM: To assess the feasibility and safety of liquid nitrogen spray cryoablation at the duodenal papilla in a porcine model. METHODS: This prospective study protocol was approved by the University of Florida Institutional Animal Care and Use Committee. Six pigs underwent liquid nitrogen spray cryotherapy at the duodenal papilla. Freeze time of 20-s was applied per cycle (4 cycles/session). Survival animals (n = 4) were monitored for adverse events. Hemoglobin, white blood count, liver tests, and lipase were obtained at baseline and post-treatment...
June 25, 2015: World Journal of Gastrointestinal Endoscopy
Chin Leng Poh, Andrew Cochrane, John C Galati, Andrew Bullock, David S Celermajer, Tom Gentles, Karin du Plessis, David S Winlaw, Tim Hornung, Kirsten Finucane, Yves d'Udekem
OBJECTIVE: To investigate the benefits of a strategy of early Fontan conversion. METHODS: Using the Australia and New Zealand Fontan Registry, retrospective analysis of their long-term follow-up data was performed. RESULTS: Between 1990 and 2014, a total of 39 patients underwent surgical conversion in 6 centres at a median age of 23.8 years (IQR: 19.3-28.2), 18.7 ± 5.0 years post-Fontan. One centre tended to perform conversion earlier: interval since first documented arrhythmia 2...
February 2016: European Journal of Cardio-thoracic Surgery
Homayoun Zargar, Dinesh Samarasekera, Ali Khalifeh, Erick M Remer, Charles O'Malley, Oktay Akca, Riccardo Autorino, Jihad H Kaouk
OBJECTIVE: To analyze our 15-year experience with small renal masses ablation and present oncologic and functional outcomes of laparoscopic cryoablation (LCA) and percutaneous cryoablation (PCA). MATERIALS AND METHODS: We identified patients who underwent LCA (n = 275) or PCA (n = 137) for small renal masses between 1997 and 2012. Differences in overall survival (OS) and recurrence-free survival (RFS) were analyzed using a log-rank test. Cox proportional hazard ratios model was used to determine factors that predicted OS...
April 2015: Urology
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