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https://www.readbyqxmd.com/read/28079859/executive-functions-in-sarcoidosis-a-neurocognitive-assessment-study
#1
Özgür Bilgin Topçuoğlu, M Kavas, Hande Alibaş, Gülgün Çetintaş Afşar, Sibel Arınç, İpek Midi, Neşe Tuncer Elmacı
Not available.
December 23, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/28044301/primary-pulmonary-mucinous-colloid-adenocarcinoma-that-arose-in-the-cavernomyoplasty-area-in-a-patient-with-tuberculosis-a-rare-case-report
#2
Neşe A Yener, Nesrin Sariman, Mehmet M Atasoy, Ahmet Midi, Alpay Örki
Primary pulmonary mucinous (colloid) adenocarcinoma is a rare type of lung cancer. Its arising in the cavernomyoplasty area has not been reported before. We here describe a sixty-year-old man with a previous history of multidrug-resistant and surgically-treated tuberculosis who was diagnosed as primary mucinous adenocarcinoma in the cavernomyoplasty site. We discuss the relevant literature on this rare entity.
2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28028074/chaperone-driven-degradation-of-a-misfolded-proinsulin-mutant-in-parallel-with-restoration-of-wild-type-insulin-secretion
#3
Corey N Cunningham, Kaiyu He, Anoop Arunagiri, Adrienne W Paton, James C Paton, Peter Arvan, Billy Tsai
In heterozygous patients with a diabetic syndrome called Mutant INS-gene-induced Diabetes of Youth (MIDY), there is decreased insulin secretion when mutant proinsulin expression prevents wild type (WT) proinsulin from exiting the endoplasmic reticulum (ER), which is essential for insulin production. Our previous results revealed that mutant Akita proinsulin is triaged by ER-associated degradation (ERAD). We now find that the ER chaperone Grp170 participates in the degradation process by shifting Akita proinsulin from high molecular weight (MW) complexes towards smaller oligomeric species that are competent to undergo ERAD...
December 27, 2016: Diabetes
https://www.readbyqxmd.com/read/28012404/influence-of-air-quality-on-the-results-of-in-vitro-fertilization-attempts-a-retrospective-study
#4
Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud, Roger Leandri
OBJECTIVE: To assess the influence of air quality on the results of IVF. STUDY DESIGN: We performed a retrospective study on 292 patients who have undergone an IVF attempt from April 2012 to December 2015 in our French university hospital. Patients were included in the study if data on the air quality at home and at work were available and if they haven't been gone for more than 4days in a month. Data were recorded during the 3 months before oocyte collection and 1 month after embryo transfer...
December 14, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28002690/diabsat-telemedicine-itinerant-screening-of-chronic-complications-of-diabetes-using-a-satellite
#5
Marie-Christine Turnin, Solène Schirr-Bonnans, Marie-Christine Chauchard, Patrice Deglise, Catherine Journot, Yann Lapeyre, Antonio Güell, Benoit Lepage, Helene Hanaire, Jacques Martini
BACKGROUND: Health authorities recommend regular screening for the chronic complications of diabetes. The ENTRED (*) survey results show that insufficient screening is undertaken. The DIABSAT (†) program aims to improve care for diabetes patients in rural areas of the Midi-Pyrénées region, telemonitoring complications of diabetes through an itinerant screening service. METHODS: A vehicle was equipped with a satellite dish and medical equipment for screening ophthalmological, renal, vascular, and neuropathic damage and assessing the level of risk of diabetic foot ulceration...
December 21, 2016: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/27960251/tropospheric-gom-at-the-pic-du-midi-observatory-correcting-bias-in-denuder-based-observations
#6
Nicolas Marusczak, Jeroen E Sonke, Xuewu Fu, Martin Jiskra
Gaseous elemental mercury (GEM, Hg) emissions are transformed to divalent reactive Hg (RM) forms throughout the troposphere and stratosphere. RM is often operationally quantified as the sum of particle bound Hg (PBM) and gaseous oxidized Hg (GOM). The measurement of GOM and PBM is challenging and under mounting criticism. Here we intercompare six months of automated GOM and PBM measurements using a Tekran (TK) KCl-coated denuder and quartz regenerable particulate filter method (GOMTK, PBMTK, and RMTK) with RMCEM collected on cation exchange membranes (CEMs) at the high altitude Pic du Midi Observatory...
December 27, 2016: Environmental Science & Technology
https://www.readbyqxmd.com/read/27923861/critical-stakeholder-determinants-to-the-implementation-of-intersectoral-community-approaches-targeting-childhood-obesity
#7
R M J J van der Kleij, M R Crone, R Reis, T G W M Paulussen
Several intersectoral community approaches targeting childhood obesity (IACOs) have been launched in the Netherlands. Translation of these approaches into practice is however arduous and implementation. We therefore studied the implementation of five IACOs in the Netherlands for one-and-a-half years. IACO implementation was evaluated via an adapted version of the MIDI questionnaire, consisting of 18 theory-based constructs. A response rate of 62% was obtained. A hierarchical multivariate linear regression model was used to analyse our data; the final regression model predicted 65% of the variance in adherence...
December 2016: Health Education Research
https://www.readbyqxmd.com/read/27895876/assessment-of-mean-glandular-dose-in-mammography-system-with-different-anode-filter-combinations-using-mcnp-code
#8
Lida Gholamkar, Ali Asghar Mowlavi, Mahdi Sadeghi, Mitra Athari
BACKGROUND: X-ray mammography is one of the general methods for early detection of breast cancer. Since glandular tissue in the breast is sensitive to radiation and it increases the risk of cancer, the given dose to the patient is very important in mammography. OBJECTIVES: The aim of this study was to determine the average absorbed dose of X-ray radiation in the glandular tissue of the breast during mammography examinations as well as investigating factors that influence the mean glandular dose (MGD)...
October 2016: Iranian Journal of Radiology: a Quarterly Journal Published By the Iranian Radiological Society
https://www.readbyqxmd.com/read/27879958/evaluation-of-a-6-year-old-multicentric-standard-endovascular-treatment-of-critical-limb-ischemia-in-the-drug-eluting-era
#9
Vincenzo Brizzi, Caroline Caradu, Xavier Berard, Gerard Sassoust, Dominique Midy, Eric Ducasse
BACKGROUND: There has been increasing evidence to support the endovascular- first approach in the treatment of below the knee (BTK) lesions. Plain Old Balloon Angioplasty (POBA), with bailout bare-metal stent scaffolding in case of flow limiting dissection or recoil, have been considered the standard treatment of choice but industries are continually developing innovative equipment and dedicated technologies, such as drug-eluting platforms whose use is increasingly extended, despite significant costs and lack of high-quality evidence to support a well- established strategy...
November 23, 2016: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27865436/-improving-adverse-drug-reaction-reporting-by-general-practitioners-through-clinical-research-assistants-visits
#10
Geneviève Durrieu, Julien Jacquot, Dominique Baudrin, Mathilde Mège, Vanessa Rousseau, Haleh Bagheri, Emmanuelle Bondon-Guitton, Delphine Abadie, François Montastruc, Michel Bismuth, Stéphane Oustric, Jean-Louis Montastruc
The main limitation of adverse drug reactions (ADRs) reporting, particularly by general practitioners (GP), to the regional pharmacovigilance centers is under-reporting. The Midi-Pyrénées Regional Pharmacovigilance Center (South western, France) sets up regular visits by a clinical research assistant (CRA) to GP in order to increase the number of ADR reports. The aim of this pilot study was to assess the effect of regular visits of a CRA in GPs offices on the rate of ADR reporting. After one year, CRA visits permit a two-fold increase in ADR reporting...
October 27, 2016: Thérapie
https://www.readbyqxmd.com/read/27835631/behavioral-quantification-of-audiomotor-transformations-in-improvising-and-score-dependent-musicians
#11
Robert Harris, Peter van Kranenburg, Bauke M de Jong
The historically developed practice of learning to play a music instrument from notes instead of by imitation or improvisation makes it possible to contrast two types of skilled musicians characterized not only by dissimilar performance practices, but also disparate methods of audiomotor learning. In a recent fMRI study comparing these two groups of musicians while they either imagined playing along with a recording or covertly assessed the quality of the performance, we observed activation of a right-hemisphere network of posterior superior parietal and dorsal premotor cortices in improvising musicians, indicating more efficient audiomotor transformation...
2016: PloS One
https://www.readbyqxmd.com/read/27835624/cuba-validated-as-the-first-country-to-eliminate-mother-to-child-transmission-of-human-immunodeficiency-virus-and-congenital-syphilis-lessons-learned-from-the-implementation-of-the-global-validation-methodology
#12
Sonja Caffe, Freddy Perez, Mary L Kamb, Rodolfo Gomez Ponce de Leon, Monica Alonso, Ralph Midy, Lori Newman, Chika Hayashi, Massimo Ghidinelli
No abstract text is available yet for this article.
December 2016: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/27787489/chimney-versus-fenestrated-endovascular-aortic-repair-for-juxta-renal-aneurysms
#13
Caroline Caradu, Xavier Berard, Gérard Sassoust, Dominique Midy, Eric Ducasse
BACKGROUND: Anatomical constrains, high price and manufacturing delay restrict fenestrated (F)-endovascular aortic repair (EVAR) to elective patients in specialized centers. Chimney graft (CG)-EVAR offers an alternative but uncertainties remain over target vessel's patency and type Ia endoleaks (ELs). METHODS: We reviewed the literature reporting F-EVAR and CG-EVAR for juxtarenal aneurysms between January 2005 and July 2016. RESULTS: Fifteen studies on F-EVAR, 8 on CG-EVAR and 5 on both techniques were included; 1748 F-EVAR patients (3993 target vessels) vs 757 (1158 target vessels, 13% symptomatic and 7% ruptured)...
October 27, 2016: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/27754209/os-31-01-blood-pressure-initial-orthostatic-hypotension-glyceryl-trinitrate-and-the-glu504lys-polymorphism-of-aldehyde-dehyrogenase-2
#14
Stephen Harrap, Angela Lamantia, James Ziogas, Jane Bourke
OBJECTIVE: Glyceryl trinitrate (GTN) is used to treat angina and lower blood pressure. The enzyme mitochondrial aldehyde dehydrogenase-2 (ALDH2) can activate GTN. The polymorphism (Gly504Lys) in the gene encoding ALDH2 is associated with significantly reduced enzyme activity and potentially diminished responses to GTN. DESIGN AND METHOD: Systolic blood pressure (SBP) was measured continuously (Finometer Midi) during 2 orthostatic challenges in 493 healthy young adults (mean age 22 y), 390 of whom took 300 μg GTN sublingually 5 min prior to the second challenge and 103 subjects of whom were untreated...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27752797/streptomyces-luozhongensis-sp-nov-a-novel-actinomycete-with-antifungal-activity-and-antibacterial-activity
#15
Renwen Zhang, Xiaoxue Han, Zhanfeng Xia, Xiaoxia Luo, Chuanxing Wan, Lili Zhang
A novel actinomycete strain, designated TRM 49605(T), was isolated from a desert soil sample from Lop Nur, Xinjiang, north-west China, and characterised using a polyphasic taxonomic approach. The strain exhibited antifungal activity against the following strains: Saccharomyces cerevisiae, Curvularia lunata, Aspergillus flavus, Aspergillus niger, Fusarium oxysporum, Penicillium citrinum, Candida albicans and Candida tropicalis; Antibacterial activity against Bacillus subtilis, Staphylococcus epidermidis and Micrococcus luteus; and no antibacterial activity against Escherichia coli...
October 17, 2016: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/27749579/drug-drug-interactions-with-imatinib-an-observational-study
#16
Isabelle Récoché, Vanessa Rousseau, Robert Bourrel, Maryse Lapeyre-Mestre, Leila Chebane, Fabien Despas, Jean-Louis Montastruc, Emmanuelle Bondon-Guitton
Many patients treated with imatinib, used in cancer treatment, are using several other drugs that could interact with imatinib. Our aim was to study all the drug-drug interactions (DDIs) observed in patients treated with imatinib.We performed 2 observational studies, between the 1st January 2012 and the 31st August 2015 in the Midi-Pyrénées area (South Western France), using the French health insurance reimbursement database and then the French Pharmacovigilance Database (FPVD).A total of 544 patients received at least 1 reimbursement for imatinib...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27738371/sexual-pain-among-malaysian-women-receiving-antidepressant-a-comparison-between-escitalopram-and-fluoxetine
#17
Hatta Sidi, Duni Asmidar, Loh Huai Seng, Nik Ruzyanei Nik Jaafar, Marhani Midi, Ng Chong Guan
OBJECTIVES: The current study compares the risk of sexual pain in depressed female patients in remission between those who were treated with Escitalopram and Fluoxetine. The associated factors were also examined. METHODS: This is a cross-sectional study involved 112 depressed female patients (56 treated with Escitalopram and 56 treated with Fluoxetine) who were in remission (as defined by Diagnostic and Statistical Manual-IV (DSM-IV) in the past 2 months and Montgomery-Asberg Depression Rating Scale (MADRS) score of ≤ 10) from the psychiatric clinic, University Kebangsaan Malaysia Medical Centre (UKMMC)...
March 1, 2016: Psychopharmacology Bulletin
https://www.readbyqxmd.com/read/27688025/completeness-of-spontaneous-adverse-drug-reaction-reports-sent-by-general-practitioners-to-a-regional-pharmacovigilance-centre-a-descriptive-study
#18
Geneviève Durrieu, Julien Jacquot, Mathilde Mège, Emmanuelle Bondon-Guitton, Vanessa Rousseau, François Montastruc, Jean-Louis Montastruc
INTRODUCTION: Spontaneous reporting of adverse drug reactions (ADRs) remains the cornerstone of postmarketing drug safety surveillance (pharmacovigilance); however, one of its main limitations is incomplete data, thus limiting conclusions about causality assessment. OBJECTIVE: The primary aim of this study was to assess the completeness of ADR reports sent by general practitioners (GPs) to regional pharmacovigilance centres and the secondary objective was to identify factors associated with complete ADR reports...
September 29, 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/27651922/association-between-rank-rankl-and-opg-polymorphisms-with-acpa-and-erosions-in-rheumatoid-arthritis-results-from-a-meta-analysis-involving-three-french-cohorts
#19
Adeline Ruyssen-Witrand, Yannick Degboé, A Cantagrel, D Nigon, C Lukas, S Scaramuzzino, Y Allanore, O Vittecoq, T Schaeverbeke, J Morel, J Sibilia, A Cambon-Thomsen, P Dieudé, A Constantin
OBJECTIVES: The RANK/RANKL/osteoprotegerin (OPG) system plays a central role in the pathogenesis of bone erosions in rheumatoid arthritis (RA). The aim of this study was to test the association between 11 single-nucleotide polymorphisms (SNPs) located on RANK, RANKL and OPG genes and anticitrullinated peptide antibody (ACPA) presence or erosions in RA. METHODS: HASH(0x49e00a0) PATIENTS: This work was performed on three independent samples of French patients with RA: the Etude de Suivi des PolyArthrites Indifférenciées Récentes (ESPOIR) (n=632), Rangueil Midi-Pyrénées (RMP) (n=249) and French Rheumatoid Arthritis Genetic Consortium (FRAGC) (n=590) cohorts...
2016: RMD Open
https://www.readbyqxmd.com/read/27643166/os-31-01-blood-pressure-initial-orthostatic-hypotension-glyceryl-trinitrate-and-the-glu504lys-polymorphism-of-aldehyde-dehyrogenase-2
#20
Stephen Harrap, Angela Lamantia, James Ziogas, Jane Bourke
OBJECTIVE: Glyceryl trinitrate (GTN) is used to treat angina and lower blood pressure. The enzyme mitochondrial aldehyde dehydrogenase-2 (ALDH2) can activate GTN. The polymorphism (Gly504Lys) in the gene encoding ALDH2 is associated with significantly reduced enzyme activity and potentially diminished responses to GTN. DESIGN AND METHOD: Systolic blood pressure (SBP) was measured continuously (Finometer Midi) during 2 orthostatic challenges in 493 healthy young adults (mean age 22 y), 390 of whom took 300 μg GTN sublingually 5 min prior to the second challenge and 103 subjects of whom were untreated...
September 2016: Journal of Hypertension
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