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https://www.readbyqxmd.com/read/29763470/the-influence-of-spinal-pelvic-parameters-on-the-prevalence-of-endplate-modic-changes-in-degenerative-thoracolumbar-lumbar-kyphosis-patients
#1
Weiwei Xia, Chenjun Liu, Shuo Duan, Shuai Xu, Kaifeng Wang, Zhenqi Zhu, Haiying Liu
BACKGROUND: The typical degeneration of the vertebral endplate shown in MRI imaging is Modic change. The aim of this study was to observe the distribution of the Modic changes of vertebral endplate in degenerative thoracolumbar/lumbar kyphosis (DTK/LK) patients and analyse the correlation between spinal-pelvic parameters and Modic changes. METHODS: The imaging data of 58 patients diagnosed with DTK/LK (coronal Cobb angle<10°with sagittal imbalance) in our hospital from March 2016 to May 2017 were reviewed retrospectively...
2018: PloS One
https://www.readbyqxmd.com/read/29757662/a-review-of-the-surgical-management-of-perineal-hernias-in-dogs
#2
Sukhjit Singh Gill, Robert D Barstad
Perineal hernia refers to the failure of the muscular pelvic diaphragm to support the rectal wall, resulting in herniation of pelvic and, occasionally, abdominal viscera into the subcutaneous perineal region. The proposed causes of pelvic diaphragm weakness include tenesmus associated with chronic prostatic disease or constipation, myopathy, rectal abnormalities, and gonadal hormonal imbalances. The most common presentation of perineal hernia in dogs is a unilateral or bilateral nonpainful swelling of the perineum...
May 14, 2018: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/29731970/elevated-seminal-plasma-estradiol-and-epigenetic-inactivation-of-esr1-and-esr2-is-associated-with-cp-cpps
#3
Nils Nesheim, Stuart Ellem, Temuujin Dansranjavin, Christina Hagenkötter, Elena Berg, Rupert Schambeck, Hans-Christian Schuppe, Adrian Pilatz, Gail Risbridger, Wolfgang Weidner, Florian Wagenlehner, Undraga Schagdarsurengin
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is associated with urinary tract symptoms and hormonal imbalances amongst others. The heterogeneous clinical presentation, unexplored molecular background and lack of prostate biopsies complicate therapy. Here, using liquid biopsies, we performed a comprehensive translational study on men diagnosed with CP/CPPS type III ( n = 50; median age 39.8, range 23-65) and age-matched controls ( n = 61; median age 36.8, range 20-69), considering biochemical parameters of blood and ejaculates, and epigenetic regulation of the estrogen receptor genes ( ESR1 and ESR2 ) in leukocytes isolated from blood (systemic regulation) and in somatic cells isolated from ejaculates (local regulation)...
April 13, 2018: Oncotarget
https://www.readbyqxmd.com/read/29723461/-related-immunologic-mechanisms-of-chronic-prostatitis-advances-in-studies
#4
REVIEW
Yi Liu, Xian-Guo Chen, Chao-Zhao Liang
Chronic prostatitis is a common male disease with a high incidence rate and a serious impact on the patients' quality of life. The pathogenesis of chronic prostatitis remains unclear though it is considered to be possibly related to infection, inflammation, and abnormal pelvic nerve muscle activity. Recently, a growing number of studies have reported immune imbalance and changes of inflammatory cytokines in patients with chronic prostatitis as well as a close correlation of abnormal immune response with the occurrence of diseases, pelvic pain symptoms, mental symptoms, hyperalgesia, and so on...
July 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29719316/the-quest-of-sagittal-balance-parameters-and-clinical-outcome-after-short-segment-spinal-fusion
#5
Rami Alqroom
Introduction: Sagittal imbalance leads to muscular distress and results in low back pain. Objectives: This study scrutinize the segmental impact of short spinal fusion on spinopelvic parameters and the global patient's clinical outcome. Materials and Methods: A retrospective analysis evaluated 56-patients who underwent lumbar fusion surgery at Klinikum Dortmund, from July 2013 to February 2014. The population was allocated into two groups: (1-level group), (2-levels group)...
2018: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/29713412/reciprocal-changes-in-sagittal-alignment-in-adolescent-idiopathic-scoliosis-patients-following-strategic-pedicle-screw-fixation
#6
Srikanth Reddy Dumpa, Ajoy Prasad Shetty, Siddharth N Aiyer, Rishi Mugesh Kanna, S Rajasekaran
Study Design: Retrospective observational study. Purpose: To analyze the effect of low-density (LD) strategic pedicle screw fixation on the correction of coronal and sagittal parameters in adolescent idiopathic scoliosis (AIS) patients. Overview of Literature: LD screw fixation achieves favorable coronal correction, but its effect on sagittal parameters is not well established. AIS is often associated with decreased thoracic kyphosis (TK), and the use of multi-level pedicle screws may result in further flattening of the sagittal profile...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29570046/sagittal-radiographic-parameters-demonstrate-weak-correlations-with-pretreatment-patient-reported-health-related-quality-of-life-measures-in-symptomatic-de-novo-degenerative-lumbar-scoliosis-a-european-multicenter-analysis
#7
Sayf S A Faraj, Marinus De Kleuver, Alba Vila-Casademunt, Roderick M Holewijn, Ibrahim Obeid, Emre Acaroğlu, Ahmet Alanay, Frank Kleinstück, Francisco S Pérez-Grueso, Ferran Pellisé
OBJECTIVE Previous studies have demonstrated that among patients with adult spinal deformity (ASD), sagittal plane malalignment is poorly tolerated and correlates with suboptimal patient-reported health-related quality of life (HRQOL). These studies included a broad range of radiographic abnormalities and various types of ASD. However, the clinical and radiographic characteristics of de novo degenerative lumbar scoliosis (DNDLS), a subtype of ASD, may influence previously reported correlation strengths. The aim of this study was to correlate sagittal radiographic parameters with pretreatment HRQOL in patients with symptomatic DNDLS...
March 23, 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29538673/recurrent-pregnancy-loss-evaluation-combined-with-24-chromosome-microarray-of-miscarriage-tissue-provides-a-probable-or-definite-cause-of-pregnancy-loss-in-over-90-of-patients
#8
F Popescu, C R Jaslow, W H Kutteh
STUDY QUESTION: Will the addition of 24-chromosome microarray analysis on miscarriage tissue combined with the standard American Society for Reproductive Medicine (ASRM) evaluation for recurrent miscarriage explain most losses? SUMMARY ANSWER: Over 90% of patients with recurrent pregnancy loss (RPL) will have a probable or definitive cause identified when combining genetic testing on miscarriage tissue with the standard ASRM evaluation for recurrent miscarriage...
April 1, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29526059/restoration-of-sagittal-balance-in-spinal-deformity-surgery
#9
REVIEW
Melvin C Makhni, Jamal N Shillingford, Joseph L Laratta, Seung-Jae Hyun, Yongjung J Kim
The prevalence of patients with adult spinal deformity (ASD) has been reported as high as 68%. ASD often leads to significant pain and disability. Recent emphasis has been placed on sagittal plane balance and restoring normal sagittal alignment with regards to the three dimensional deformity of ASD. Optimal sagittal alignment has been known to increase spinal biomechanical efficiency, reduce energy expenditure by maintaining a stable posture with improved load absorption, influence better bony union, and help to decelerate adjacent segment deterioration...
March 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29452257/microbiota-changes-impact-on-sexually-transmitted-infections-and-the-development-of-pelvic-inflammatory-disease
#10
Nathalie Loeper, Simon Graspeuntner, Jan Rupp
The integrity of the human urogenital microbiome is crucial for women's health and well-being. An imbalance of the urogenital microbiota increases the risk for sexually transmitted infections. In this review, we discuss the microbiota composition of the female urogenital tract and its role in protecting from sexually transmitted infections and the emergence of pelvic inflammatory disease.
February 13, 2018: Microbes and Infection
https://www.readbyqxmd.com/read/29424672/sacral-pedicle-subtraction-osteotomy-for-an-extreme-case-of-positive-sagittal-balance-case-report
#11
Ali K Ozturk, Patricia Zadnik Sullivan, Vincent Arlet
The importance of sagittal spinal balance and lumbopelvic parameters is now well understood. The popularization of various osteotomies, including Smith-Peterson, Ponte, and pedicle subtraction osteotomies (PSOs), as well as vertebral column resections, have greatly enhanced the spine surgeon's ability to recognize and effectively treat sagittal imbalance. Yet rare circumstances remain, most notably in distal kyphotic deformities and patients with extremely elevated pelvic incidences, where these techniques remain inadequate...
May 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29417322/sagittal-imbalance-treated-with-l5-pedicle-subtraction-osteotomy-with-short-lumbar-fusion-from-l4-to-sacrum-using-four-screws-into-l4-for-enhanced-fixation-two-additional-vertebral-screws-a-technical-note
#12
Kuenzang Wangdi, Bungo Otsuki, Shunsuke Fujibayashi, Shimei Tanida, Kazutaka Masamoto, Shuichi Matsuda
PURPOSE: To report on suggested technique with four screws in a single vertebra (two pedicle screws and two direct vertebral body screws) for enhanced fixation with just one level cranially to a pedicle subtraction osteotomy (PSO). METHODS: A 60-year-old woman underwent L4/5 fusion surgery for degenerative spondylolisthesis. Two years later, she was unable to stand upright even for a short time because of lumbar kyphosis caused by subsidence of the fusion cage and of Baastrup syndrome in the upper lumbar spine [sagittal vertical axis (SVA) of 114 mm, pelvic incidence of 75°, and lumbar lordosis (LL) of 41°]...
February 7, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29413731/the-berbeo-sardi-angle-bsa-an-innovative-method-to-effectively-estimate-pelvic-retroversion-in-anteroposterior-radiographs-a-correlation-with-traditional-parameters
#13
Juan P Sardi, Jorge E Camacho, Roberto C Diaz, Miguel E Berbeo
STUDY: Design: Diagnostic studies-concordance between diagnostic tests. OBJECTIVES: The purpose of this study was to develop a novel spinopelvic parameter (Berbeo-Sardi angle [BSA], the angle formed at the intersection of a line that connects the inferior margin of the sacroiliac joint to the midpoint of a horizontal line joining both femoral heads) measurable in anteroposterior radiographs that indirectly estimates pelvic retroversion and correlates with traditional measurements like pelvic tilt (PT)...
March 2018: Spine Deformity
https://www.readbyqxmd.com/read/29409817/botulinum-toxin-treatment-of-pain-syndromes-an-evidence-based-review
#14
Yasaman Safarpour, Bahman Jabbari
This review evaluates the existing level of evidence for efficacy of BoNTs in different pain syndromes using the recommended efficacy criteria from the Assessment and Therapeutic Subcommittee of the American Academy of Neurology. There is a level A evidence (effective) for BoNT therapy in post-herpetic neuralgia, trigeminal neuralgia, and posttraumatic neuralgia. There is a level B evidence (probably effective) for diabetic neuropathy, plantar fasciitis, piriformis syndrome, pain associated with total knee arthroplasty, male pelvic pain syndrome, chronic low back pain, male pelvic pain, and neuropathic pain secondary to traumatic spinal cord injury...
June 1, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29396766/analysis-of-cervical-sagittal-alignment-variations-after-lumbar-pedicle-subtraction-osteotomy-for-severe-imbalance-study-of-59-cases
#15
W Thompson, A Cogniet, M Challali, R Saddiki, J Rigal, Jean Charles Le Huec
OBJECTIVE: To evaluate postoperative changes within the cervical alignment following surgical lumbar correction by pedicle subtraction osteotomy (PSO) in patients affected with sagittal global malalignment disease. METHODS: This was a monocentric, radiographic, and prospective study. 79 patients, who underwent sagittal correction by PSO, performed an EOS imaging pre- and postoperatively between January 2008 and December 2013 at the University Hospital of Bordeaux...
February 2018: European Spine Journal
https://www.readbyqxmd.com/read/29376610/-the-role-of-stress-induced-chronic-subclinical-inflammation-in-the-pathogenesis-of-the-chronic-pelvic-pain-syndrome-iiib-in-men
#16
REVIEW
I S Shormanov, I I Mozhaev, Kh A Sokolova, A S Solovev
This literature review of recent clinical and experimental studies describes the role of oxidative stress in the multifactorial and interdisciplinary pathogenesis of non-inflammatory chronic pelvic pain syndrome IIIB (CPPS-IIIB) in men. The authors outline general biological nature of oxidative stress and its mechanisms. More detailed information is presented on cytokine-mediated chronic subclinical inflammation, one of the key mechanisms of oxidative stress, which is currently being actively studied. It is shown that the imbalance between pro- and anti-inflammatory cytokines observed in patients with CPPS-IIIB can explain some features of the clinical course (in particular, the characteristics of the pain syndrome) and the progression of this disease...
December 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29360579/l5-incidence-an-important-parameter-for-spinopelvic-balance-evaluation-in-high-grade-spondylolisthesis
#17
Amer Sebaaly, Rami El Rachkidi, Pierre Grobost, Marion Burnier, Hubert Labelle, Pierre Roussouly
BACKGROUND: In high-grade spondylolisthesis (HGSPL), the pelvic incidence (PI) is not a reliable measurement because of doming of the sacrum. Measurement of L5 incidence (L5I) was described as a tool to measure pelvic morphology in HGSPL and for surgical follow-up. OBJECTIVE: We aimed to evaluate L5I in HGSPL and its relationship to other spinopelvic parameters. STUDY DESIGN: A retrospective study of a cohort of 184 patients with HGSPL was carried out...
January 31, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29358108/increased-pt-ss-may-play-an-important-role-in-the-pathogenesis-of-lumbar-spondylolisthesis-with-degenerative-lumbar-scoliosis
#18
Jinlei Zhang, Yong Hai, Jincai Yang, Aixing Pan, Yangpu Zhang
OBJECTIVE: To explore the clinical and spinopelvic features in patients with lumbar spondylolisthesis and degenerative lumbar scoliosis (LSDLS) and those with standalone lumbar spondylolisthesis (SALS). PATIENTS AND METHODS: We retrospectively analyzed 130 patients with lumbar spondylolisthesis seen between 05/2013 and 12/2016 in our hospital. Propensity score matching was used to reduce an age distribution imbalance between the two groups. Clinical and spinopelvic parameters were compared by independent samples t test and chi-square test...
March 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29335900/hypercomplex-pedicle-subtraction-osteotomies-definition-early-clinical-and-radiological-results-and-complications
#19
Pedro Berjano, Andrea Zanirato, Domenico Compagnone, Andrea Redaelli, Marco Damilano, Claudio Lamartina
PURPOSE: To describe hypercomplex pedicle subtraction osteotomies (HyC-PSO) for adult spine deformity with sagittal imbalance in terms of preoperative, intraoperative and postoperative outcomes and complications. METHODS: From a prospective single centre database, patients undergoing PSO between January 2016 and May 2017 were reviewed. HyC-PSO were defined as those in patients with one of the following conditions: sagittal correction > 45° needed at a single level or at 1-3 consecutive vertebrae, more than 60° of total sagittal correction needed and PSO on segments of the spine with congenital deformities...
February 2018: European Spine Journal
https://www.readbyqxmd.com/read/29274599/bowel-obstruction-in-obturator-hernia-a-challenging-diagnosis
#20
L Conti, E Baldini, P Capelli, C Capelli
INTRODUCTION: The obturator hernia is a rare pelvic hernia that often comes in the shape of bowel obstruction caused by the presence of an intestinal segment, more often ileum, passing trough the obturator foramen of the pelvic wall (Fig. 1). This type of hernia accounts for 0.5-1.4% of all hernias. CASE PRESENTATION: We report the clinical case of a 84-year-old woman with no previous surgical interventions, who went to the emergency room complaining of vomit and nausea, bowels closed to gas and stool, which she had experienced for three previous days...
2018: International Journal of Surgery Case Reports
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