keyword
MENU ▼
Read by QxMD icon Read
search

Glucosamine AND chondroitin

keyword
https://www.readbyqxmd.com/read/28192075/the-effect-of-additive-compounds-on-glycerol-induced-damage-to-human-chondrocytes
#1
Joshua Hahn, Leila Laouar, Janet A W Elliott, Gregory S Korbutt, Nadr M Jomha
High concentrations of cryoprotective agents are required for cryopreservation techniques such as vitrification. Glycerol is a common cryoprotective agent used in cryopreservation protocols but this agent is toxic at high concentrations. This work is an attempt to mitigate the toxic effects of high concentrations of glycerol on intact chondrocytes in human knee articular cartilage from total knee arthroplasty patients by simultaneous exposure to glycerol and a variety of additive compounds. The resulting cell viability in the cartilage samples as measured by membrane integrity staining showed that, in at least one concentration or in combination, all of the tested additive compounds (tetramethylpyrazine, ascorbic acid, chondroitin sulphate, glucosamine sulphate) were able to reduce the deleterious effects of glycerol exposure when examination of membrane integrity took place on a delayed time frame...
February 10, 2017: Cryobiology
https://www.readbyqxmd.com/read/28144573/glucosamine-and-chondroitin-for-the-treatment-of-osteoarthritis
#2
EDITORIAL
Haris S Vasiliadis, Konstantinos Tsikopoulos
The prevalence of primary or idiopathic osteoarthritis (OA) of knee and hip joints has substantially increased in general population during the last decades. Analgesics and non-steroidal anti-inflammatory drugs are currently extensively used as non-surgical treatment options. However, they act as symptomatic treatments, not offering a cure of OA and they are accused for an increased risk of adverse events. Glucosamine (GL) and chondroitin (CH) are nutritional supplements that have recently gained widespread use as treatment options for OA...
January 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28104792/new-insight-into-chondroitin-and-heparosan-like-capsular-polysaccharide-synthesis-by-profiling-of-the-nucleotide-sugar-precursors
#3
Odile Francesca Restaino, Irene di Lauro, Rosaria Di Nuzzo, Mario De Rosa, Chiara Schiraldi
Escherichia coli K4 and K5 capsular polysaccharides have been used as starting material for the biotechnological production of chondroitin sulfate and heparin, respectively. The capsular polysaccharide covers the outer cell wall but in late exponential or stationary growth phase it is started to be released in the surrounding medium. The released capsular polysaccharide concentration was used, so far, as the only marker to connect the strain production ability to the different cultivation conditions employed...
January 19, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28080917/results-of-the-megaverebrate-analgesia-survey-giraffe-and-hippopotamus
#4
Matthew Boothe, Jack Kottwitz, Roy Harmon, Scott B Citino, Jeffery R Zuba, Dawn M Boothe
Results of an online survey posted on the American Association of Zoo Veterinarians listserv examined the patterns of analgesic medication and pain management modalities used for captive giraffe and hippopotami. Compiled data included signalment, drugs administered, dosing regimens, subjective efficacy scores, ease of administration, and adverse events. Nineteen institutions exhibiting hippopotami ( Hippopotamus amphibious ) and pygmy hippopotami (Choeropsis liberiensis) and 45 exhibiting giraffe ( Giraffa camelopardalis spp...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28078503/efficacy-of-pulsed-nd-yag-laser-in-the-treatment-of-patients-with-knee-osteoarthritis-a-randomized-controlled-trial
#5
Mohamed Salaheldien Mohamed Alayat, Tarek Helmy Ahmed Aly, Aly Elsayed Mohamed Elsayed, Ammar Suliman Mohamed Fadil
The purpose of this study was to investigate the effects of pulsed Nd:YAG laser plus glucosamine/chondroitin sulfate (GCS) in patients with knee osteoarthritis (KOA) by examining changes in pain and knee function, as well as synovial thickness (ST) and femoral cartilage thickness (FCT). Sixty-seven male patients participated, with a mean (SD) age of 53.85 (4.39) years, weight of 84.01 (4.70) kg, height of 171.51 (3.96) cm, and BMI of 28.56 (1.22). Group 1 was treated with high-intensity laser therapy (HILT), GCS, and exercises (HILT + GCS + EX)...
January 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/27980494/in-vivo-osteoinduction-evaluating-2-beta-coxatene-as-an-immunoinductive-compound-and-novel-ingredient-for-joint-support
#6
Katherine Spinks, James J Scaffidi
CONTEXT: Osteoarthritis (OA) is a degenerative joint disease characterized by progressive loss of articular cartilage. Many treatments lack the ability to stimulate the growth of native cartilage tissue while they simultaneously increase joint comfort. For the past few decades, dietary supplements have been investigated for the ability to both address joint inflammation and stimulate cartilage tissue. OBJECTIVES: The present study intended to examine the supplement's in vivo osteoinductive capabilities and clinical efficacy for overall joint health...
October 2016: Integrative Medicine
https://www.readbyqxmd.com/read/27971486/impact-of-glucosamin-and-chondroitin-sulfates-combination-gcsc-on-the-burden-of-osteorthritis-over-6-months-in-portugal-an-observational-study
#7
H Mateus, A Pires, A Zkik, G Berdeaux, M Auges, R Hemery
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/27912939/dietary-supplementation-is-more-prevalent-among-adults-with-arthritis-in-the-united-states-population
#8
Patrick B Wilson
OBJECTIVES: Sparse data are available to describe the prevalence of dietary supplementation among individuals with arthritis. Using a nationally representative sample, this investigation assessed the prevalence of dietary supplement use among Americans self-reporting arthritis. SETTING AND DESIGN: Data from 4606 participants of the 2011-2012 National Health and Nutrition Examination Survey were analyzed, including from 1170 participants self-reporting arthritis...
December 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27909553/effects-of-gangliosides-from-deer-bone-extract-on-the-gene-expressions-of-matrix-metalloproteinases-and-collagen-type-ii-in-interleukin-1%C3%AE-induced-osteoarthritic-chondrocytes
#9
Hyung Joo Suh, Hyunji Lee, Byung Jung Min, Sung Ug Jung, Eun Young Jung
BACKGROUND/OBJECTIVES: We investigated the anti-osteoarthritic effects of deer bone extract on the gene expressions of matrix metalloproteinases (MMPs) and collagen type II (COL2) in interleukin-1β-induced osteoarthritis (OA) chondrocytes. MATERIALS/METHODS: Primary rabbit chondrocytes were treated as follows: CON (PBS treatment), NC (IL-1β treatment), PC (IL-1β + 100 µg/mL glucosamine sulphate/chondroitin sulphate mixture), and DB (IL-1β + 100 µg/mL deer bone extract)...
December 2016: Nutrition Research and Practice
https://www.readbyqxmd.com/read/27845067/the-combined-therapy-with-chondroitin-sulfate-plus-glucosamine-sulfate-or-chondroitin-sulfate-plus-glucosamine-hydrochloride-does-not-improve-joint-damage-in-an-experimental-model-of-knee-osteoarthritis-in-rabbits
#10
Jorge A Roman-Blas, Aránzazu Mediero, Lidia Tardío, Sergio Portal-Nuñez, Paula Gratal, Gabriel Herrero-Beaumont, Raquel Largo
Osteoarthritis is the most common chronic joint disorder especially during aging. Although with controversies, glucosamine, both in its forms of sulfate and hydrochloride, and chondroitin sulfate are commonly employed to treat osteoarthritis. Due to the modest improve in the symptoms observed in patients treated with these drugs alone, a formulation combining both agents has been considered. The discrepant results achieved for pain control or structural improvement in osteoarthritis patients has been attributed to the quality of chemical formulations or different bias in clinical studies...
January 5, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27826450/dachslife-2015-an-investigation-of-lifestyle-associations-with-the-risk-of-intervertebral-disc-disease-in-dachshunds
#11
R M A Packer, I J Seath, D G O'Neill, S De Decker, H A Volk
BACKGROUND: Intervertebral disc disease (IVDD) represents a major problem in the Dachshund, with at a relative risk of IVDD 10-12 times higher than other breeds, and an estimated 19-24 % of Dachshunds showing clinical signs related to IVDD during their lifetime. A variety of genetic, physical and lifestyle-related risk factors for IVDD have previously been identified, with some conflicting findings. As such, advising owners and breeders regarding best-practice for IVDD prevention is challenging at present...
2016: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/27668577/efficacy-of-intravenous-administration-of-hyaluronan-sodium-chondroitin-sulfate-and-n-acetyl-d-glucosamine-for-prevention-or-treatment-of-osteoarthritis-in-horses
#12
RANDOMIZED CONTROLLED TRIAL
David D Frisbie, C Wayne McIlwraith, Christopher E Kawcak, Natasha M Werpy
OBJECTIVE To evaluate the efficacy of IV administration of a product containing hyaluronan, sodium chondroitin sulfate, and N-acetyl-d-glucosamine for prevention or treatment of osteoarthritis in horses. ANIMALS 32 healthy 2- to 5-year-old horses. PROCEDURES The study involved 2 portions. To evaluate prophylactic efficacy of the test product, horses received 5 mL of the product (n = 8) or saline (0.9% NaCl) solution (8; placebo) IV every fifth day, starting on day 0 (when osteoarthritis was induced in the middle carpal joint of 1 forelimb) and ending on day 70...
October 2016: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/27594189/evidence-based-evaluation-of-complementary-health-approaches-for-pain-management-in-the-united-states
#13
REVIEW
Richard L Nahin, Robin Boineau, Partap S Khalsa, Barbara J Stussman, Wendy J Weber
Although most pain is acute and resolves within a few days or weeks, millions of Americans have persistent or recurring pain that may become chronic and debilitating. Medications may provide only partial relief from this chronic pain and can be associated with unwanted effects. As a result, many individuals turn to complementary health approaches as part of their pain management strategy. This article examines the clinical trial evidence for the efficacy and safety of several specific approaches-acupuncture, manipulation, massage therapy, relaxation techniques including meditation, selected natural product supplements (chondroitin, glucosamine, methylsulfonylmethane, S-adenosylmethionine), tai chi, and yoga-as used to manage chronic pain and related disability associated with back pain, fibromyalgia, osteoarthritis, neck pain, and severe headaches or migraines...
September 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27477804/combined-treatment-with-chondroitin-sulfate-and-glucosamine-sulfate-shows-no-superiority-over-placebo-for-reduction-of-joint-pain-and-functional-impairment-in-patients-with-knee-osteoarthritis-a-six-month-multicenter-randomized-double-blind-placebo-controlled
#14
Jorge A Roman-Blas, Santos Castañeda, Olga Sánchez-Pernaute, Raquel Largo, Gabriel Herrero-Beaumont
OBJECTIVE: To assess the efficacy and safety of combination therapy with chondroitin sulfate (CS) and glucosamine sulfate (GS) compared to placebo in patients with symptomatic knee osteoarthritis (OA). METHODS: A multicenter, randomized, double-blind, placebo-controlled study was performed in 164 patients with Kellgren/Lawrence grade 2 or grade 3 radiographic knee OA and moderate-to-severe knee pain (mean ± SD global pain score 62.1 ± 11.3 mm on a 100-mm visual analog scale [VAS])...
January 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27451370/polymer-surface-adsorption-as-a-strategy-to-improve-the-biocompatibility-of-graphene-nanoplatelets
#15
Artur M Pinto, J Agostinho Moreira, Fernão D Magalhães, Inês C Gonçalves
The biointeractions of graphene-based materials depend on their physico-chemical properties. These properties can be manipulated by polymer adsorption. Graphene nanoplatelets (GNP-C) were modified with PVA, HEC, PEG, PVP, chondroitin, glucosamine, and hyaluronic acid. These materials were characterized by SEM, DLS, XPS, Raman spectroscopy, and TGA. Surface adsorption was confirmed for all polymers. Biocompatibility evaluation showed that all of these materials induced low haemolysis (<1.7%) at concentrations up to 500μgmL(-1)...
October 1, 2016: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/27382267/glucosamine-containing-supplement-improves-locomotor-functions-in-subjects-with-knee-pain-a-pilot-study-of-gait-analysis
#16
Noriyuki Kanzaki, Yuta Otsuka, Takayuki Izumo, Hiroshi Shibata, Hideyuki Nagao, Keita Ogawara, Hiroshi Yamada, Seiji Miyazaki, Yutaka Nakamura
BACKGROUND: Previously, we demonstrated that glucosamine-containing supplementation was effective for improving locomotor functions, especially walking speed. However, the biomechanical mechanism of efficacy has not been elucidated. This study aimed to address this challenge in subjects with knee pain, using a motion capture system. METHODS: An open label study was conducted in 30 Japanese subjects with knee pain. The subjects were administered a daily supplement containing 1,200 mg of glucosamine hydrochloride, 60 mg of chondroitin sulfate, 45 mg of type II collagen peptides, 90 mg of quercetin glycosides, 10 mg of imidazole peptides, 1 mg of proteoglycan, and 5 μg of vitamin D (GCQID)...
2016: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/27357024/use-of-glucosamine-and-chondroitin-supplements-in-relation-to-risk-of-colorectal-cancer-results-from-the-nurses-health-study-and-health-professionals-follow-up-study
#17
Elizabeth D Kantor, Xuehong Zhang, Kana Wu, Lisa B Signorello, Andrew T Chan, Charles S Fuchs, Edward L Giovannucci
Recent epidemiologic evidence has emerged to suggest that use of glucosamine and chondroitin supplements may be associated with reduced risk of colorectal cancer (CRC). We therefore evaluated the association between use of these non-vitamin, non-mineral supplements and risk of CRC in two prospective cohorts, the Nurses' Health Study and Health Professionals Follow-up Study. Regular use of glucosamine and chondroitin was first assessed in 2002 and participants were followed until 2010, over which time 672 CRC cases occurred...
November 1, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27331031/nutraceutical-supplement-in-the-management-of-tendinopathies-a-systematic-review
#18
REVIEW
Federico Fusini, Salvatore Bisicchia, Carlo Bottegoni, Antonio Gigante, Fabio Zanchini, Alberto Busilacchi
BACKGROUND: nutraceuticals are common support therapy for management of tendinopathies. Even if they are widely diffused, our knowledge is still poor. The aim of this systematic review is to analyze the most commonly used nutraceuticals and their effects on tendons. METHODS: glucosamine and chondroitin sulphate, vitamin C, hydrolazed type 1 collagen, arginine alpha-keto-glutarate, bromelain, curcumin, boswellic acid, and methil-sulfonil-methane were considered. During the last week of Dicember 2015 a comprehensive research of main databases for each substance was made in relation with tendinopathy...
January 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27304775/chondroitin-glucosamine-equal-to-celecoxib-for-knee-osteoarthritis
#19
Allen F Shaughnessy
No abstract text is available yet for this article.
June 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27267755/the-ple-2-no-self-management-and-exercise-program-for-knee-osteoarthritis-study-protocol-for-a-randomized-controlled-trial
#20
Priscila Marconcin, Margarida Espanha, Flávia Yázigi, Pedro Campos
BACKGROUND: International recommendations suggest exercise and self-management programs, including non-pharmacological treatments, for knee osteoarthritis (KOA) because they can benefit pain relief and improve function and exercise adherence. The implementation of a combined self-management and exercise program termed PLE(2)NO may be a good method for controlling KOA symptoms because it encourages the development of self-efficacy to manage the pathology. This study will assess the effects of a self-management and exercise program in comparison to an educational intervention (control program) on symptoms, physical fitness, health-related quality of life, self-management behaviors, self-efficacy, physical activity level and coping strategies...
June 7, 2016: BMC Musculoskeletal Disorders
keyword
keyword
51826
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"