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https://www.readbyqxmd.com/read/28418891/risk-of-aortic-aneurysm-and-dissection-in-patients-with-autosomal-dominant-polycystic-kidney-disease-a-nationwide-population-based-cohort-study
#1
Pei-Hsun Sung, Yao-Hsu Yang, Hsin-Ju Chiang, John Y Chiang, Chi-Jen Chen, Chien-Ting Liu, Cheuk-Man Yu, Hon-Kan Yip
Although cardiovascular complications are the most common cause of death in patients with autosomal-dominant polycystic kidney disease (ADPKD), the incidence and risk of aortic aneurysm and dissection (AAD) in ADPKD remains unclear due to limited data and insufficient cases. We utilized the data from Taiwan National Health Insurance Research Database (NHIRD) to do a population-based cohort study (1997-2008). After excluding those patients with age <18 years old and initially concomitant diagnoses of end-stage renal disease and AAD, a total of 2076 ADPKD patients were selected from 1,000,000 of general population...
March 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/28408829/sleep-apnea-and-the-subsequent-risk-of-parkinson-s-disease-a-3-year-nationwide-population-based-study
#2
Ping-Song Chou, Chiou-Lian Lai, Yii-Her Chou, Wei-Pin Chang
PURPOSE: Sleep apnea (SA)-induced chronic intermittent hypoxia increases oxidative stress and inflammation, which may contribute to the pathophysiology of Parkinson's disease (PD). This study evaluated the risk of PD following SA diagnosis. PATIENTS AND METHODS: This was a 3-year nationwide population-based matched cohort study using claims data from the National Health Insurance Research Database (NHIRD), Taiwan. We analyzed 1,944 patients diagnosed as having SA between 1997 and 2005 and a matched cohort of 9,720 non-SA patients from the NHIRD...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28384235/risk-analysis-of-use-of-different-classes-of-antidepressants-on-subsequent-dementia-a-nationwide-cohort-study-in-taiwan
#3
Chee-Kin Then, Nai-Fang Chi, Kuo-Hsuan Chung, Lynn Kuo, Kao-Hui Liu, Chaur-Jong Hu, Shing-Chuan Shen, Yen-Kuang Lin
Depression and dementia are common mental health problems and are associated in several ways. Early-life depression is associated with increased risk of later life dementia, and depression can present as a preclinical symptom or consequence of dementia. Despite the plausible relationship between these two clinical entities, the potential association between antidepressant medication and dementia has rarely been investigated. We conducted a 9-year retrospective analysis of Taiwan's National Health Insurance Research Database (NHIRD), enrolling 5819 cases who had received prescriptions of antidepressants between 2003 and 2006, and 23,276 (with ratio of 1:4) age, sex, and index date-matched controls...
2017: PloS One
https://www.readbyqxmd.com/read/28359982/bidirectional-association-between-bell-s-palsy-and-anxiety-disorders-a-nationwide-population-based-retrospective-cohort-study
#4
Chih-Chieh Tseng, Li-Yu Hu, Mu-En Liu, Albert C Yang, Cheng-Che Shen, Shih-Jen Tsai
OBJECTIVE: Bell's palsy and anxiety disorders share numerous risk factors (e.g., immune response, ischemia, and psychological stress). However, there have been no studies on the bidirectional temporal association between the two illnesses. In this study, we used the Taiwan National Health Insurance Research Database (NHIRD) to test the bidirectional association between Bell's palsy and anxiety disorders. We hypothesized that patients with Bell's palsy would have an increased risk of subsequent anxiety disorders later in life and that, conversely, those with anxiety disorders would have an increased likelihood of developing Bell's palsy later in life...
March 27, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28356725/is-diabetes-mellitus-associated-with-clinical-outcomes-in-aging-males-treated-with-transurethral-resection-of-prostate-for-bladder-outlet-obstruction-implications-from-taiwan-nationwide-population-based-cohort-study
#5
Yu-Hsiang Lin, Chen-Pang Hou, Tien-Hsing Chen, Horng-Heng Juang, Phei-Lang Chang, Pei-Shan Yang, Yu-Sheng Lin, Chien-Lun Chen, Ke-Hung Tsui
PURPOSE: We assessed the lower urinary tract symptoms (LUTSs) and clinical outcomes between diabetes mellitus (DM) patients and non-diabetic (non-DM) patients receiving transurethral resection of prostate (TUR-P). METHODS: This analysis was a retrospective cohort study using 13 years (2000-2012) of claims data from Taiwan's National Health Insurance Research Database (NHIRD). A total of 4,887 patients who had persistent LUTSs and underwent TUR-P for prostate enlargement (benign prostate enlargement [BPE]) were enrolled and divided into two groups: DM and non-DM groups...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28356117/association-of-traditional-chinese-medicine-therapy-and-the-risk-of-dementia-in-patients-with-hypertension-a-nationwide-population-based-cohort-study
#6
Kuen-Hau Chen, Ming-Hsien Yeh, Hanoch Livneh, Bor-Chyuan Chen, I-Hsin Lin, Ming-Chi Lu, Tzung-Yi Tsai, Chia-Chou Yeh
BACKGROUND: Patients with hypertension (HTN) reportedly have a higher risk of developing dementia. However, it remains unclear if use of Traditional Chinese Medicine (TCM), the most common form of complementary and alternative medicine, can help lower the risk of dementia for these patients. So the aim of the study was to investigate the effects of TCM on dementia risk among patients with hypertension. METHODS: This longitudinal cohort study used the Taiwanese National Health Insurance Research Database (NHIRD) to identify 143,382 newly diagnosed hypertension patients aged 20-90 years who received treatment between 1998 and 2007...
March 29, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28350822/asthma-corticosteroid-use-and-schizophrenia-a-nationwide-population-based-study-in-taiwan
#7
Wei-Chen Wang, Mong-Liang Lu, Vincent Chin-Hung Chen, Mei-Hing Ng, Kuo-You Huang, Ming-Hong Hsieh, Meng-Jer Hsieh, Roger S McIntyre, Yena Lee, Charles Tzu-Chi Lee
OBJECTIVE: Asthma and corticosteroid use have been implicated as possible risk factors for schizophrenia. The retrospective cohort study herein aimed to investigate the association between asthma, corticosteroid use, and schizophrenia. METHOD: Longitudinal data (2000 to 2007) from adults with asthma (n = 50,046) and without asthma (n = 50,046) were compared on measures of schizophrenia incidence using Taiwan's National Health Insurance Research Database (NHIRD)...
2017: PloS One
https://www.readbyqxmd.com/read/28328577/parkinson-disease-and-musculoskeletal-pain-an-8-year-population-based-cohort-study
#8
Wei-Hung Lien, Wei-Chih Lien, Ta-Shen Kuan, Shang-Te Wu, Yi-Ting Chen, Ching-Ju Chiu
The aim of this study was to evaluate the incidence and clinical features of musculoskeletal pain (MSP) in patients with Parkinson disease (PD) compared with a control group without the disease. The retrospective cohort study used a subset of the Taiwan National Health Insurance Research Database (NHIRD) comprising information on 1 million beneficiaries randomly sampled from the entire population of Taiwan. A total of 490 patients aged 50 and above with newly diagnosed Parkinson disease were identified during a period from 2000 to 2005...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28288163/increased-risk-of-essential-tremor-in-migraine-a-population-based-retrospective-cohort-study
#9
Chi-Ieong Lau, Che-Chen Lin, Hsuan-Ju Chen, Han-Cheng Wang, Wei-Hung Chen, Ji-An Liang
PURPOSE: To examine the long-term risk of essential tremor (ET) in migraine. METHODS: Using population-based administrative data from a subset of the National Health Insurance Research Database (NHIRD) of Taiwan, we identified 22,696 newly diagnosed migraineurs (mean age 44.5 years) and a matched migraine-free cohort of 90,784 individuals in the period 2000-2008. Multivariable Cox proportional hazards regression analysis was conducted for assessing the ET risk for the migraine cohort compared to the migraine-free cohort...
2017: PloS One
https://www.readbyqxmd.com/read/28229293/age-related-hearing-loss-and-dementia-a-10-year-national-population-based-study
#10
Peijen Su, Chih-Chao Hsu, Hung-Ching Lin, Wei-Shin Huang, Tsung-Lin Yang, Wei-Ting Hsu, Cheng-Li Lin, Chung-Yi Hsu, Kuang-Hsi Chang, Yi-Chao Hsu
Age-related hearing loss (ARHL) is postulated to affect dementia. Our study aims to investigate the relationship between ARHL and the prevalence, and 10-year incidence of dementia in the Taiwan National Health Insurance Research Database (NHIRD). We selected patients diagnosed with ARHL from the NHIRD. A comparison cohort comprising of patients without ARHL was frequency-matched by age, sex, and co-morbidities, and the occurrence of dementia was evaluated in both cohorts. The ARHL cohort consisted of 4108 patients with ARHL and the control cohort consisted of 4013 frequency-matched patients without ARHL...
February 22, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28137521/gender-based-differences-in-mortality-and-complementary-therapies-for-patients-with-stroke-in-taiwan
#11
Chun-Ting Liu, Bei-Yu Wu, Wen-Long Hu, Yu-Chiang Hung
BACKGROUND: Stroke is a leading cause of death worldwide. In this retrospective study, we investigated the different effects of gender on medical behavior, medical service, medical cost, and death from stroke in Taiwan. METHODS: We collected data on the stroke-associated mortality rate according to gender and age group for the period between 2009 and 2013 from the official registry of Ministry of Health and Welfare, Taiwan. We analyzed the data related to stroke-associated medical care and costs in 2013 from the National Health Insurance Research Database (NHIRD)...
February 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28124984/acute-anterior-uveitis-as-a-risk-factor-of-ankylosing-spondylitis-a-national-population-based-study
#12
Ju-Chuan Yen, Chia-An Hsu, Sheng-Huang Hsiao, Min-Huei Hsu
INTRODUCTION: In clinical settings, acute anterior uveitis (AAU) could be the first presentation of ankylosing spondylitis (AS). Based on this hypothesis, we investigate whether AAU is a risk factor in developing AS later by using National Health Insurance Research Database (NHIRD) in Taiwan. MATERIALS AND METHODS: This cohort comparison study used longitudinal Taiwanese NHIRD to probe the relative risk odds of AAU for AS development, and consisted of all patients diagnosed with AAU (n = 5621) (ICD-9-CM codes 364...
January 23, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28104794/measuring-inequality-in-physician-distributions-using-spatially-adjusted-gini-coefficients
#13
Yi-Hsin Elsa Hsu, Wender Lin, Joseph J Tien, Larry Y Tzeng
Objective: To measure inequality in physician distributions using Gini coefficient and spatially adjusted Gini coefficients. Design: Measurements were based on the distribution of physician data from the Taiwan National Health Insurance Research Database (NHIRD) and population data from the Ministry of the Interior in Taiwan. Settings: The distribution of population and physicians in Taiwan from 2001 to 2010. Participants: This study considered 35 000 physicians who are registered in Taiwan...
December 1, 2016: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28102720/do-racial-differences-exist-in-the-association-between-pregnancy-induced-hypertension-and-breast-cancer-risk
#14
Li-Te Lin, Li-Yu Hu, Pei-Ling Tang, Kuan-Hao Tsui, Jiin-Tsuey Cheng, Wei-Chun Huang, Hong-Tai Chang
BACKGROUND: Previous studies investigating the relationship between pregnancy-induced hypertension (PIH) and breast cancer risk have yielded inconsistent results. Unlike numerous Western studies, studies have reported that PIH may be a risk factor for breast cancer in Western Asian women. To confirm these results, we designed a retrospective population-based cohort study to assess the relationship between PIH and subsequent risk for breast cancer in Taiwan. METHODS: Patients with newly diagnosed PIH were selected from the Taiwan National Health Insurance Research Database (NHIRD), and a 1:4 matched cohort of women without PIH based on age and the year of delivery was randomly selected from the same database as the comparison group...
January 19, 2017: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/28069909/pregnancy-increases-stroke-risk-up-to-one-year-postpartum-and-reduces-long-term-risk
#15
Chun-An Cheng, Jiunn-Tay Lee, Hung-Che Lin, Hui-Chen Lin, Chi-Hsiang Chung, Fu-Huang Lin, Chang-Huei Tsao, Yung-Fu Wu, Wu-Chien Chien, Hung-Wen Chiu
BackgroundThe incidence of stroke in pregnant women is low but trending upward. There are few studies of the topic in women of Asian ethnicity.AimWe aim to evaluate stroke risk in Asian women during and after pregnancy.DesignUsing the Taiwan National Health Insurance database (NHIRD), we designed a retrospective study that included 18-45-year-old pregnant women between the years 2000 and 2010. We selected a 1:1 age-matched control group of non-pregnant women. The endpoint was any type of stroke during pregnancy or the postpartum period; otherwise, the patients were tracked until December 31, 2010...
January 9, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28056095/ischemic-bowel-syndrome-in-patients-with-spinal-cord-injury-a-nationwide-study
#16
Chih-Wei Tseng, Cheng-Li Lin, Yu-Tso Chen, Long-Bin Jeng
PURPOSE: The aim of this study was to determine whether spinal cord injuries (SCI) is associated with increased risk of ischemic bowel syndrome (IBS) in an Asian population by analyzing data from the National Health Insurance Research Database (NHIRD) in Taiwan. METHODS: Patients aged ≥20 years in the inpatient database with newly identified SCI from 2000 to 2011 were selected as the SCI cohort. For the non-SCI cohort, patients were selected based on a 1:4 risk-set sampling...
2017: PloS One
https://www.readbyqxmd.com/read/28038444/an-association-between-autosomal-dominant-polycystic-kidney-disease-and-the-risk-of-acute-myocardial-infarction-in-asian-population-results-of-a-nationwide-study
#17
Pei-Hsun Sung, Hsin-Ju Chiang, Yao-Hsu Yang, Chi-Jen Chen, John Y Chiang, Hon-Kan Yip
Cardiovascular complications are the leading causes of death in patients with autosomal-dominant polycystic kidney disease (ADPKD) in the Western countries. However, theprevalence and risk of acute myocardial infarction (AMI) in patients with ADPKD remain unknown, especially in Asian population. We utilized the data from Taiwan National Health Insurance Research Database (NHIRD) to perform a population-based cohort study (1997-2008). A total of 2062 patients with ADPKD were selected from one million of general population after excluding those patients with age less than 18 years old, receiving renal replacement therapy, and concomitant diagnoses of AMI...
March 21, 2017: Oncotarget
https://www.readbyqxmd.com/read/27988835/cost-effectiveness-analysis-of-apixaban-dabigatran-rivaroxaban-and-warfarin-for-stroke-prevention-in-atrial-fibrillation-in-taiwan
#18
Chieh-Yu Liu, Hui-Chun Chen
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the cost effectiveness of novel oral anticoagulants (NOACs) for stroke prevention among atrial fibrillation (AF) patients by incorporating Taiwanese demographic information derived from a population-based database, the National Health Insurance Research Database (NHIRD), into cost-effectiveness analysis. METHODS: From 1 January to 31 December 2012, 98,213 AF patients were selected from the NHIRD database...
March 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/27974236/integrative-therapy-decreases-the-risk-of-lupus-nephritis-in-patients-with-systemic-lupus-erythematosus-a-population-based-retrospective-cohort-study
#19
Ching-Mao Chang, Po-Chang Wu, Jen-Huai Chiang, Yau-Huei Wei, Fang-Pey Chen, Tzeng-Ji Chen, Tai-Long Pan, Hung-Rong Yen, Hen-Hong Chang
ETHNOPHARMACOLOGICAL RELEVANCE: Evidence on alleviating the risk of lupus nephritis by integrative therapy with conventional medicine (CM) and herbal medicine (HM) had not been addressed. AIM OF THE STUDY: We investigated the integrative effect associated the risk by a retrospective Systemic Lupus Erythematosus (SLE) cohort from Taiwan National Health Insurance Research Database (NHIRD). MATERIALS AND METHODS: SLE patients with a catastrophic illness certificate (CIC) were retrospectively enrolled from the SLE cohort of the Taiwan NHIRD between 1997 and 2011...
January 20, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27972882/estimating-the-economic-burden-of-treatment-resistant-depression-in-taiwan-using-the-nhird
#20
J Klug, F Yu, C Chang, H Juang, M Wang, D Fife, C Liu, B C Wang
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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