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https://www.readbyqxmd.com/read/28427913/predicting-the-stone-composition-of-children-preoperatively-by-hounsfield-unit-detection-on-non-contrast-computed-tomography
#1
Mesut Altan, Burak Çitamak, Ali Cansu Bozaci, Altan Güneş, Hasan Serkan Doğan, Mithat Haliloğlu, Serdar Tekgül
INTRODUCTION: Many studies have been performed on adult patients to reveal the relationship between Hounsfield unit (HU) value and composition of stone, but none have focused on childhood. OBJECTIVE: We aimed to predict stone composition by HU properties in pre-intervention non-contrast computed tomography (NCCT) in children. This could help to orient patients towards more successful interventions. MATERIALS AND METHODS: Data of 94 children, whose pre-intervention NCCT and post-interventional stone analysis were available were included...
March 31, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28389784/findings-from-the-initial-use-of-the-healthy-homes-rating-system-hhrs-in-three-american-cities
#2
Katelyn Burkart, Jonatan Martinez, Alicia Streater, Lyke Thompson
HUD's Healthy Homes Rating System (HHRS) is a modification of the English version, using scoring values developed in England. The goal of the HUD Three-City Healthy Homes Rating System (HHRS) study was to create a baseline of the prevalence and severity of 29 home health hazards in three cities-Detroit, MI; Greensboro, NC; and Alameda County, CA-and to compare the results to the prevalence and severity found in England. We analyzed 978 housing assessments over 3 years. Hygrothermal hazards (e.g., excess cold) were the most prevalent across the sites...
April 7, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28338690/a-viscous-solvent-enables-information-transfer-from-gene-length-nucleic-acids-in-a-model-prebiotic-replication-cycle
#3
Christine He, Isaac Gállego, Brandon Laughlin, Martha A Grover, Nicholas V Hud
Many hypotheses concerning the nature of early life assume that genetic information was once transferred through the template-directed synthesis of RNA, before the emergence of coded enzymes. However, attempts to demonstrate enzyme-free, template-directed synthesis of nucleic acids have been limited by 'strand inhibition', whereby transferring information from a template strand in the presence of its complementary strand is inhibited by the stability of the template duplex. Here, we use solvent viscosity to circumvent strand inhibition, demonstrating information transfer from a gene-length template (>300 nt) within a longer (545 bp or 3 kb) duplex...
April 2017: Nature Chemistry
https://www.readbyqxmd.com/read/28334877/iron-mediates-catalysis-of-nucleic-acid-processing-enzymes-support-for-fe-ii-as-a-cofactor-before-the-great-oxidation-event
#4
C Denise Okafor, Kathryn A Lanier, Anton S Petrov, Shreyas S Athavale, Jessica C Bowman, Nicholas V Hud, Loren Dean Williams
Life originated in an anoxic, Fe2+-rich environment. We hypothesize that on early Earth, Fe2+ was a ubiquitous cofactor for nucleic acids, with roles in RNA folding and catalysis as well as in processing of nucleic acids by protein enzymes. In this model, Mg2+ replaced Fe2+ as the primary cofactor for nucleic acids in parallel with known metal substitutions of metalloproteins, driven by the Great Oxidation Event. To test predictions of this model, we assay the ability of nucleic acid processing enzymes, including a DNA polymerase, an RNA polymerase and a DNA ligase, to use Fe2+ in place of Mg2+ as a cofactor during catalysis...
April 20, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28334706/repetitive-dna-a-versatile-tool-for-karyotyping-in-festuca-pratensis-huds
#5
Anna Křivánková, David Kopecký, Štěpán Stočes, Jaroslav Doležel, Eva Hřibová
FISH is a useful method to identify individual chromosomes in a karyotype and to discover their structural changes accompanying genome evolution and speciation. DNA probes for FISH should be chromosome specific and/or exhibit specific patterns of distribution along each chromosome. Such probes are not available in many plants including meadow fescue (Festuca pratensis Huds.), an important forage grass species. In the present study, various DNA repeats identified in Illumina shotgun sequences specific to chromosome 4F of F...
March 24, 2017: Cytogenetic and Genome Research
https://www.readbyqxmd.com/read/28207335/housing-assistance-programs-and-adult-health-in-the-united-states
#6
Andrew Fenelon, Patrick Mayne, Alan E Simon, Lauren M Rossen, Veronica Helms, Patricia Lloyd, Jon Sperling, Barry L Steffen
OBJECTIVES: To examine whether access to housing assistance is associated with better health among low-income adults. METHODS: We used National Health Interview Survey data (1999-2012) linked to US Department of Housing and Urban Development (HUD) administrative records (1999-2014) to examine differences in reported fair or poor health and psychological distress. We used multivariable models to compare those currently receiving HUD housing assistance (public housing, housing choice vouchers, and multifamily housing) with those who will receive housing assistance within 2 years (the average duration of HUD waitlists) to account for selection into HUD assistance...
April 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28192095/cigarette-smoking-and-adverse-health-outcomes-among-adults-receiving-federal-housing-assistance
#7
Veronica E Helms, Brian A King, Peter J Ashley
Cigarette smoking is higher among low-income adults and individuals who reside in federally assisted housing are particularly susceptible to the adverse effects of smoking and secondhand smoke exposure. This study assessed smoking-related behaviors and health outcomes among U.S. adults who received federal housing assistance during 2006-2012. National Health Interview Survey data linked with administrative data from the U.S. Department of Housing and Urban Development were analyzed; 5218 HUD-assisted adults were assessed...
February 10, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28186420/driving-while-interacting-with-google-glass
#8
Kathryn G Tippey, Elayaraj Sivaraj, Thomas K Ferris
OBJECTIVE: This study evaluated the individual and combined effects of voice (vs. manual) input and head-up (vs. head-down) display in a driving and device interaction task. BACKGROUND: Advances in wearable technology offer new possibilities for in-vehicle interaction but also present new challenges for managing driver attention and regulating device usage in vehicles. This research investigated how driving performance is affected by interface characteristics of devices used for concurrent secondary tasks...
February 1, 2017: Human Factors
https://www.readbyqxmd.com/read/28182604/announcement-federally-assisted-housing-standards-for-blood-lead-levels-aligned-with-cdc-recommended-threshold
#9
(no author information available yet)
On January 13, 2017, the U.S. Department of Housing and Urban Development (HUD) lowered the threshold of lead in young children's blood that triggers interventions to evaluate and control exposure hazards from 20 μg/dL to 5 μg/dL, matching the reference level used by CDC (1). The rule includes a process to continue HUD alignment with any future updates to CDC's reference level (1).
February 10, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28150176/health-hazards-in-the-home-an-assessment-of-a-southern-nevada-community
#10
Amanda Sokolowsky, Erika Marquez, Erin Sheehy, Casey Barber, Shawn Gerstenberger
As a sub-grantee of a Department of Housing and Urban Development (HUD) Lead Hazard Control and Healthy Homes Program, the University of Nevada, Las Vegas' Department of Environmental and Occupational Health performed lead and Healthy Homes investigations and collected data regarding conditions in the home environment in Henderson, Nevada. The purpose of this research is to characterize housing conditions in southern Nevada, compare data to census data, and to highlight the health outcomes associated with adverse housing conditions...
February 1, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28113076/expression-of-flhma3-a-p1b2-atpase-from-festulolium-loliaceum-correlates-with-response-to-cadmium-stress
#11
Qiang Guo, Lin Meng, Mike W Humphreys, John Scullion, Luis A J Mur
Heavy metal ATPase 3 (HMA3), a P1B2-ATPase, is a key tonoplast transporter involved in mediating the vacuolar sequestration of cadmium (Cd) to detoxify the intake of this element by plants. HMA3 expression in response to Cd stress has not been previously examined in the grass hybrid species Festulolium loliaceum (Huds.) P. Fourn. In this study, FlHMA3 isolated from F. loliaceum was found to comprise 833 amino acid residues with 77% homology to the rice OsHMA3. Transient expression of FlHMA3 fused to enhanced green fluorescent protein in Arabidopsis protoplasts suggested its localization to vacuolar membranes...
January 16, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28111162/hud-mediated-distinct-bdnf-regulatory-pathways-promote-regeneration-after-nerve-injury
#12
Maria Domenica Sanna, Carla Ghelardini, Nicoletta Galeotti
Up-regulation of brain-derived neurotrophic factor (BDNF)synthesis is an important mechanism of peripheralnerveregenerationafterinjury.However, the cellular and molecular mechanisms underlying this process are not fully understood. This study examines the role of BDNF in the spared nerve injury (SNI) mice model. Protein expression and cellular localization were investigated in the dorsal root ganglia (DRG) and spinal cord by western blotting and immunofluorescence experiments respectively. BDNF protein was markedly increased 3 and 7 days post-injury in the spinal cord and DRG...
January 19, 2017: Brain Research
https://www.readbyqxmd.com/read/28108383/traditional-uses-of-medicinal-plants-reported-by-the-indigenous-communities-and-local-herbal-practitioners-of-bajaur-agency-federally-administrated-tribal-areas-pakistan
#13
Muhammad Abdul Aziz, Amir Hasan Khan, Muhammad Adnan, Izatullah Izatullah
ETHNOPHARMACOLOGICAL RELEVANCE: In the study area, knowledge related to the traditional uses of medicinal plants is totally in the custody of elder community members and local herbalists. The younger generation is unaware of the traditional knowledge, however with only few exceptions. Therefore, this study was planned with objective to document the medicinal importance of plants, conserve this precious indigenous knowledge, and share it among other communities through published literature...
January 17, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28103063/delivering-on-the-promise-of-smoke-free-public-housing
#14
Douglas E Levy, Inez F Adams, Gary Adamkiewicz
On November 30, 2016, the US Department of Housing and Urban Development (HUD) published a final rule mandating that public housing authorities it supports prohibit all smoking on their residential premises, including within residents' apartments. The primary rationale for this action was to protect nonsmoking residents from the harms of tobacco smoke exposure. Although the harms of secondhand smoke are clear and the potential for reducing nonsmoking residents' exposure is real, it will be no simple matter to successfully implement the policy requirements set down by HUD...
March 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28102982/requirements-for-notification-evaluation-and-reduction-of-lead-based-paint-hazards-in-federally-owned-residential-property-and-housing-receiving-federal-assistance-response-to-elevated-blood-lead-levels-final-rule
#15
(no author information available yet)
This final rule amends HUD's lead-based paint regulations to reduce blood lead levels in children under age six (6) who reside in federally-owned or -assisted pre-1978 housing, formally adopting a revised definition of "elevated blood lead level" (EBLL) in children under the age of six (6), in accordance with Centers for Disease Control and Prevention (CDC) guidance. It also establishes more comprehensive testing and evaluation procedures for the housing where such children reside. This final rule also addresses certain additional elements of the CDC guidance pertaining to assisted housing and makes technical corrections and clarifications...
January 13, 2017: Federal Register
https://www.readbyqxmd.com/read/28008603/a-pilot-randomized-controlled-trial-of-the-effects-of-chair-yoga-on-pain-and-physical-function-among-community-dwelling-older-adults-with-lower-extremity-osteoarthritis
#16
Juyoung Park, Ruth McCaffrey, David Newman, Patricia Liehr, Joseph G Ouslander
OBJECTIVES: To determine effects of Sit 'N' Fit Chair Yoga, compared to a Health Education program (HEP), on pain and physical function in older adults with lower extremity osteoarthritis (OA) who could not participate in standing exercise. DESIGN: Two-arm randomized controlled trial. SETTING: One HUD senior housing facility and one day senior center in south Florida. PARTICIPANTS: Community-dwelling older adults (N = 131) were randomly assigned to chair yoga (n = 66) or HEP (n = 65)...
March 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27940343/factors-contributing-to-eviction-from-permanent-supportive-housing-lessons-from-hud-vash
#17
Ann Elizabeth Montgomery, Meagan Cusack, Dorota Szymkowiak, Jamison Fargo, Thomas O'Toole
INTRODUCTION: Eviction from housing is associated with several negative outcomes, further exacerbated among high-need populations requiring financial and supportive services to maintain housing stability. This study investigated risk and protective factors-both characteristics and precipitating events of tenant eviction-informing permanent supportive housing (PSH) programs' efforts to identify tenants at risk and intervene. METHODS: Using administrative data for a cohort of 20,146 Veterans participating in PSH, this study assessed differences in Veterans who exited the program due to eviction and Veterans who exited because they accomplished their goals...
December 2, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/27927076/evidence-of-biological-activity-of-mentha-species-extracts-on-apoptotic-and-autophagic-targets-on-murine-raw264-7-and-human-u937-monocytic-cells
#18
Fatiha Brahmi, Samia Hadj-Ahmed, Amira Zarrouk, Maryem Bezine, Thomas Nury, Khodir Madani, Mohamed Chibane, Anne Vejux, Pierre Andreoletti, Lila Boulekbache-Makhlouf, Gérard Lizard
CONTEXT: Mints (Lamiaceae) are used as traditional remedies for the treatment of several diseases. Their extracts are recognized as anti-inflammatory compounds. OBJECTIVE: This study characterized the cytotoxic effects of Mentha spicata L. (MS), Mentha pulegium L. (MP) and Mentha rotundifolia (L). Huds (MR) on macrophage cells (RAW264.7; U937) and determined their impact on apoptosis and autophagy, which can play a role in controlling inflammation. MATERIALS AND METHODS: The extracts were prepared in culture medium and tested from 25 to 400 μg/mL after 24-48 h of treatment...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27905561/anti-hu-antibodies-activate-enteric-and-sensory-neurons
#19
Qin Li, Klaus Michel, Anita Annahazi, Ihsan E Demir, Güralp O Ceyhan, Florian Zeller, Lars Komorowski, Winfried Stöcker, Michael J Beyak, David Grundy, Gianrico Farrugia, Roberto De Giorgio, Michael Schemann
IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneoplastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung carcinoma. We show here that IgG isolated from such sera and also affinity-purified anti-HuD label enteric neurons and cause an immediate spike discharge in enteric and visceral sensory neurons. Both labelling and activation of enteric neurons was prevented by preincubation with the HuD antigen. Activation of enteric neurons was inhibited by the nicotinic receptor antagonists hexamethonium and dihydro-β-erythroidine and reduced by the P2X antagonist pyridoxal phosphate-6-azo (benzene-2,4-disulfonic acid (PPADS) but not by the 5-HT3 antagonist tropisetron or the N-type Ca-channel blocker ω-Conotoxin GVIA...
December 1, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27902806/orthology-guided-transcriptome-assembly-of-italian-ryegrass-and-meadow-fescue-for-single-nucleotide-polymorphism-discovery
#20
Štěpán Stočes, Tom Ruttink, Jan Bartoš, Bruno Studer, Steven Yates, Zbigniew Zwierzykowski, Michael Abrouk, Isabel Roldán-Ruiz, Tomasz Książczyk, Elodie Rey, Jaroslav Doležel, David Kopecký
Single-nucleotide polymorphisms (SNPs) represent natural DNA sequence variation. They can be used for various applications including the construction of high-density genetic maps, analysis of genetic variability, genome-wide association studies, and map-based cloning. Here we report on transcriptome sequencing in the two forage grasses, meadow fescue ( Huds.) and Italian ryegrass ( Lam.), and identification of various classes of SNPs. Using the Orthology Guided Assembly (OGA) strategy, we assembled and annotated a total of 18,952 and 19,036 transcripts for Italian ryegrass and meadow fescue, respectively...
November 2016: Plant Genome
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