Christian van Delden, Susanne Stampf, Hans H Hirsch, Oriol Manuel, Pascal Meylan, Alexia Cusini, Cédric Hirzel, Nina Khanna, Maja Weisser, Christian Garzoni, Katja Boggian, Christoph Berger, David Nadal, Michael Koller, Ramon Saccilotto, Nicolas J Mueller
BACKGROUND: The burden and timeline of posttransplant infections are not comprehensively documented in the current era of immunosuppression and prophylaxis. METHODS: In this prospective study nested within the Swiss Transplant Cohort Study (STCS), all clinically relevant infections were identified by transplant-infectious diseases physicians in persons receiving solid organ transplant (SOT) between May 2008 and December 2014 with ≥12 months of follow-up. RESULTS: Among 3541 SOT recipients, 2761 (1612 kidney, 577 liver, 286 lung, 213 heart, and 73 kidney-pancreas) had ≥12 months of follow-up; 1520 patients (55%) suffered 3520 infections during the first year posttransplantation...
October 23, 2020: Clinical Infectious Diseases