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https://www.readbyqxmd.com/read/29132957/allergy-terminology-towards-a-common-language-and-shared-understanding
#1
Michael Levin
Terminology that is used in an inconsistent and ambiguous way by allergists includes the term "cross reactivity" and the use of the word "positive" when referring to allergy tests. This may have serious potential for miscommunication and adversely affect patient care.
November 10, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29132668/diagnosis-and-management-of-eosinophilic-esophagitis
#2
REVIEW
Jeffrey M Wilson, Emily C McGowan
Unlike traditional food allergies, immunoglobulin E (IgE) is not a key mediator of eosinophilic esophagitis (EoE). Nonetheless, foods antigens are important triggers of EoE, and allergists play an important role in management of this chronic disease. This review addresses insights into the diagnosis and management as it relates to our evolving understanding about the pathogenesis of EoE.
February 2018: Immunology and Allergy Clinics of North America
https://www.readbyqxmd.com/read/29131356/gluten-sensitivities-and-the-allergist-threshing-the-grain-from-the-husks
#3
REVIEW
J G Burkhardt, A Chapa-Rodriguez, S L Bahna
"Gluten sensitivity" has become commonplace among the public. Wheat allergy (WA) and celiac disease (CD) are well-defined entities, but are becoming a fraction of individuals following a gluten-free diet. WA has a prevalence of <0.5%. Wheat, specifically its omega-5 gliadin fraction, is the most common allergen implicated in food-dependent, exercise-induced anaphylaxis. CD is a non-IgE hypersensitivity to certain cereal proteins: gluten in wheat, secalin in rye, hordein in barley, and to a lesser extent avenin in oat...
November 13, 2017: Allergy
https://www.readbyqxmd.com/read/29118675/selecting-optimal-second-generation-antihistamines-for-allergic-rhinitis-and-urticaria-in-asia
#4
Marysia Tiongco Recto, Ma Teresita Gabriel, Kanokvalai Kulthanan, Pongsakorn Tantilipikorn, Derrick Chen-Wee Aw, Tak Hong Lee, Ch'ng Chin Chwen, Somasundran Mutusamy, Nguyen Trong Hao, Vo Thanh Quang, Giorgio Walter Canonica
Background: Allergic diseases are on the rise in many parts of the world, including the Asia-Pacific (APAC) region. Second-generation antihistamines are the first-line treatment option in the management of allergic rhinitis and urticaria. International guidelines describe the management of these conditions; however, clinicians perceive the additional need to tailor treatment according to patient profiles. This study serves as a consensus of experts from several countries in APAC (Hong Kong, Malaysia, the Philippines, Singapore, Thailand, Vietnam), which aims to describe the unmet needs, practical considerations, challenges, and key decision factors when determining optimal second-generation antihistamines for patients with allergic rhinitis and/or urticaria...
2017: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29103799/american-college-of-allergy-asthma-immunology-position-paper-on-the-use-of-telemedicine-for-allergists
#5
Tania Elliott, Jennifer Shih, Chitra Dinakar, Jay Portnoy, Stanley Fineman
The integration of telecommunications and information systems in health care first began 4 decades ago with 500 patient consultations performed via interactive television. The use of telemedicine services and technology to deliver health care at a distance is increasing exponentially. Concomitant with this rapid expansion is the exciting ability to provide enhancements in quality and safety of care. Telemedicine enables increased access to care, improvement in health outcomes, reduction in medical costs, better resource use, expanded educational opportunities, and enhanced collaboration between patients and physicians...
November 2, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29099994/-the-occupational-physician-s-role-in-the-detection-and-official-recognition-of-occupational-skin-diseases
#6
Rocío Villar Vinuesa, José Mª Ramada Rodilla, Consol Serra Pujadas
Occupational and work-related skin diseases include all skin conditions (as well as those involving the mucous membranes and cutaneous annexes) that are caused, conditioned, aggravated or promoted directly or indirectly by workplace risk factors. Occupational health physicians (OP) are involved in all phases of the natural history of the disease: prevention, early detection, diagnosis, clinical management, and providing advice and support to the company and the worker in all these stages. This paper provides an in-depth review of the role of the OP throughout this process, underscoring the importance of coordination with the dermatologist and/or the allergist...
October 2017: Archivos de Prevención de Riesgos Laborales
https://www.readbyqxmd.com/read/29094889/chronic-rhinosinusitis
#7
Ahmad R Sedaghat
Chronic rhinosinusitis is an inflammatory disease of the paranasal sinuses that occurs in 1% to 5% of the U.S. POPULATION: It may significantly decrease quality of life. Chronic rhinosinusitis is defined by the presence of at least two out of four cardinal symptoms (i.e., facial pain/pressure, hyposmia/anosmia, nasal drainage, and nasal obstruction) for at least 12 consecutive weeks, in addition to objective evidence. Objective evidence of chronic rhinosinusitis may be obtained on physical examination (anterior rhinoscopy, endoscopy) or radiography, preferably from sinus computed tomography...
October 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29094518/disparities-in-rate-triggers-and-management-in-pediatric-and-adult-cases-of-suspected-drug-induced-anaphylaxis-in-canada
#8
REVIEW
Sofianne Gabrielli, Ann E Clarke, Harley Eisman, Judy Morris, Lawrence Joseph, Sebastien La Vieille, Peter Small, Rodrick Lim, Paul Enarson, Michal Zelcer, Edmond S Chan, Chris Mill, Moshe Ben-Shoshan
INTRODUCTION: Data is sparse on drug-induced anaphylaxis (DIA) and there have not been studies assessing the differences in clinical characteristics and management of DIA between adults and children. OBJECTIVE: We assessed the percentage, diagnosis, and management of DIA among all anaphylaxis visits in three pediatric and one adult emergency departments (ED) across Canada. METHODS: Children presenting to the Montreal Children's Hospital (MCH), British Columbia Children's Hospital (BCCH), and Children's Hospital at London Health Sciences Center and adults presenting to Hôpital du Sacré-Coeur with anaphylaxis were recruited as part of the Cross-Canada Anaphylaxis Registry...
November 1, 2017: Immunity, Inflammation and Disease
https://www.readbyqxmd.com/read/29046189/high-adherence-to-subcutaneous-immunotherapy-in-a-real-life-study-from-a-large-tertiary-medical-center
#9
Aslı Gelincik, Semra Demir, Müge Olgaç, Halim İşsever, Bayerma Khishigsuren, Ferhan Özşeker, Bahauddin Çolakoğlu, Suna Büyüköztürk
BACKGROUND: Studies on real-life adherence to subcutaneous allergen immunotherapy (SCIT) for respiratory allergy are scarce. The aim of this study was to evaluate adherence to SCIT. METHODS: The patients prescribed SCIT for allergic rhinitis and/or asthma in 2009-2011 were contacted in 2014 and asked whether they completed at least the 3 years of SCIT and/or whether they suspended the treatment for at least 2 months. The Total Symptom Score-6, visual analog scale (VAS), asthma control test (ACT), medication scores, quality of life (QoL) scores, and immunotherapy satisfaction scores with VAS obtained before the initiation of SCIT in the first year and at the end of SCIT were compared...
November 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28977301/cross-cultural-adaptation-and-validation-of-the-itching-severity-scale-in-children-and-adolescents-with-atopic-dermatitis
#10
Dayanne Mota Veloso Bruscky, Ana Caroline Cavalcanti Dela Bianca Melo, Emanuel Sávio Cavalcanti Sarinho
OBJECTIVE: To translate, adapt and validate the Itch Severity Scale to a Brazilian version (ISS-Ped) in order to measure the severity of pruritus in children and adolescents with atopic dermatitis. METHODS: This is a methodological study of validation of an instrument following recommended protocols. The translated version was evaluated by a group of experts including one professional with experience in instrument validation, three English teachers, one linguistics teacher and seven allergists...
July 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28970084/expert-perspectives-on-management-of-moderate-to-severe-atopic-dermatitis-a-multidisciplinary-consensus-addressing-current-and-emerging-therapies
#11
REVIEW
Mark Boguniewicz, Andrew F Alexis, Lisa A Beck, Julie Block, Lawrence F Eichenfield, Luz Fonacier, Emma Guttman-Yassky, Amy S Paller, David Pariser, Jonathan I Silverberg, Mark Lebwohl
Atopic dermatitis (AD) is a common, chronic, relapsing, inflammatory skin disease that affects children and adults. Until recently, the only Food and Drug Administration-approved systemic treatment option for patients with moderate-to-severe AD was systemic steroids, which are not recommended by current guidelines and are commonly associated with disease rebound. Instead, clinicians choose from several off-label immunosuppressants, which can have serious adverse effects. A significant number of these patients go untreated...
September 29, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28965637/aspirin-and-nonsteroidal-antiinflammatory-drugs-hypersensitivity-and-management
#12
REVIEW
Brian Modena, Andrew A White, Katharine M Woessner
Aspirin and nonsteroidal antiinflammatory drugs (NSAIDs) are widely used in the United States and throughout the world for a variety of indications. Several unique hypersensitivity syndromes exist to this class of medications, making them one of the common reasons for consultation to the allergist. The lack of any laboratory-based diagnostic studies to assist in identifying the culprits in these reactions make evaluation of aspirin and NSAID hypersensitivity challenging. Identifying patients appropriate for oral challenge and/or desensitization protocols is the standard pragmatic approach to this issue when it arises...
November 2017: Immunology and Allergy Clinics of North America
https://www.readbyqxmd.com/read/28958738/the-cost-of-penicillin-allergy-evaluation
#13
Kimberly G Blumenthal, Yu Li, Aleena Banerji, Brian J Yun, Aidan A Long, Rochelle P Walensky
BACKGROUND: Unverified penicillin allergy leads to adverse downstream clinical and economic sequelae. Penicillin allergy evaluation can be used to identify true, IgE-mediated allergy. OBJECTIVE: To estimate the cost of penicillin allergy evaluation using time-driven activity-based costing (TDABC). METHODS: We implemented TDABC throughout the care pathway for 30 outpatients presenting for penicillin allergy evaluation. The base-case evaluation included penicillin skin testing and a 1-step amoxicillin drug challenge, performed by an allergist...
September 22, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28940450/national-clinical-practice-guidelines-for-allergen-immunotherapy-an-international-assessment-applying-agree-ii
#14
D E S Larenas-Linnemann, D Antolín-Amérigo, C Parisi, A Nakonechna, J A Luna-Pech, B Wedi, I Davila, M Gómez, M Levin, J A Ortega Martell, L Klimek, N Rosario, A M Muraro, I Agache, J Bousquet, A Sheikh, O Pfaar
BACKGROUND: Since 1988, numerous allergen immunotherapy guidelines (AIT-GLs) have been developed by national and international organizations to guide physicians in AIT. Even so, AIT is still severely underused. OBJECTIVE: To evaluate AIT-GLs with AGREE-II, developed in 2010 by McMaster University methodologists to comprehensively evaluate GL quality. METHODS: Allergist, from different continents, knowledgeable in AIT and AGREE-II trained were selected into the project team...
September 21, 2017: Allergy
https://www.readbyqxmd.com/read/28904734/a-17-year-old-male-with-a-small-bowel-neuroendocrine-tumor-flushing-differential-diagnosis
#15
Maria Alejandra Forero Molina, Elizabeth Garcia, Deyanira Gonzalez-Devia, Rafael García-Duperly, Alonso Vera
BACKGROUND: Neuroendocrine tumors (NETs) are heterogeneous neoplasms that originate from cells with a secretory function. Small bowel NETs (SB-NETs) are related to serotonin hypersecretion which causes: flushing, diarrhea, abdominal pain, bronchoconstriction and heart involvement, also known as carcinoid syndrome (CS). CS can be confused with an allergic reaction and thus should be considered as a differential diagnosis in the allergy consult. We present the case of a pediatric patient initially referred under the suspicion of food allergies...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28893128/urticarial-reaction-following-endovascular-embolization-of-an-orbital-arteriovenous-malformation-avm-with-n-butyl-cyanoacrylate-nbca-glue
#16
Kunal R Sinha, Gary Duckwiler, Daniel B Rootman
Orbital arteriovenous malformations (AVMs) are rare vascular lesions that may be managed with endovascular embolization followed by surgical resection. Embolization is often accomplished with n-butyl-2-cyanoacrylate (nBCA), which is considered to be a safe and effective liquid occlusive agent. Localized vascular inflammation has been associated with endovascular nBCA use in histopathologic studies, but reports of systemic hypersensitivity reactions following endovascular embolization with nBCA are rare. We present a case of a 26-year-old male who developed an intermittent systemic urticarial reaction without cardiopulmonary compromise beginning four weeks after nBCA embolization of an orbital AVM...
December 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28886960/-indoor-air-quality-and-parents-of-asthmatic-children-practices
#17
S Larramendy Magnin, B Desssome, L Moret
BACKGROUND: Indoor air pollution can worsen asthma in children. Better knowledge of factors determining parents' reception of recommendations to limit pollution of indoor air in the homes of asthmatic children would be helpful to improve implementation. METHOD: A descriptive study evaluating practices known to have an impact on the quality of air in homes was conducted among parents of asthmatic children aged 3 to 16 years. From May to September 2013, parents answered anonymous self-administered questionnaires in waiting rooms of generalist practitioners, in the Nantes University pneumology pediatric outpatient clinic, and as part of therapeutic education sessions conducted by the Asthma-44 Network...
September 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28871584/selected-aspects-of-medical-care-for-patients-with-asthma-and-chronic-obstructive-pulmonary-disease-copd-in-poland
#18
Joanna Miłkowska-Dymanowska, Adam J Białas, Paweł Górski
INTRODUCTION: Noncompliance with healthcare undoubtedly has a strong influence on the high prevalence of uncontrolled obstructive diseases. The aim of our study was to evaluate the quality of medical conduct in patients with asthma or chronic obstructive lung diseases (COPD), with encompassed two-levelled system of health care. MATERIAL AND METHODS: A survey of general practitioners (GP), allergists and pulmonologists practicing in Poland was performed between September and December 2016...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28865233/first-allergenic-pollen-monitoring-in-bucharest-and-results-of-three-years-collaboration-with-european-aerobiology-specialists
#19
Polliana Mihaela Leru, Ana-Maria Eftimie, Michel Thibaudon
INTRODUCTION: Respiratory allergies induced by allergenic plants pollen represent an important public health problem with increasing prevalence and severity. Aerobiologic study of allergenic pollens is performed in many countries on regular basis and correlated with health data from allergists in the frame of national aerobiology networks. Romania has no aerobiology network and pollen measurements have been done between 1999-2012 in West region only. In the frame of COST Action called Sustainable management of Ambrosia Artemisiifolia in Europe (SMARTER FA 1203), three years collaboration with Reseau National de Surveillance Aerobiologique (RNSA) from France and the first pollen monitoring center in Bucharest were established...
August 28, 2017: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/28852410/management-of-chronic-spontaneous-urticaria-csu-a-treat-to-target-approach-using-a-patient-reported-outcome
#20
Hermenio Lima, Melinda Gooderham, Jan Dutz, Charles Lynde, Hugo Chapdelaine, Anne Ellis, Martin Gilbert, Vincent Ho, Kim Papp, Yves Poulin, Gordon Sussman
BACKGROUND: Treat-to-target therapy approaches are established for chronic diseases such as diabetes, hypertension, and more recently rheumatoid arthritis, resulting in improved patient outcomes. These approaches do not use patient reported outcomes (PRO) as targets of therapy. Chronic spontaneous urticaria (CSU), also called chronic idiopathic urticaria (CIU), is defined as recurrent urticaria of known and unknown cause, lasting more than 6 weeks. Treatment of CSU can be challenging...
2017: Allergy, Asthma, and Clinical Immunology
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