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https://www.readbyqxmd.com/read/29343976/epidemiology-associated-burden-and-current-clinical-practice-for-the-diagnosis-and-management-of-alzheimer-s-disease-in-japan
#1
REVIEW
William Montgomery, Kaname Ueda, Margaret Jorgensen, Shari Stathis, Yuanyuan Cheng, Tomomi Nakamura
The burden of dementia in Japan is large and growing. With the world's fastest aging population, it is estimated that one in five elderly people will be living with dementia in Japan by 2025. The most common form of dementia is Alzheimer's disease (AD), accounting for around two-thirds of dementia cases. A systematic review was conducted to examine the epidemiology and associated burden of AD in Japan and to identify how AD is diagnosed and managed in Japan. English and Japanese language databases were searched for articles published between January 2000 and November 2015...
2018: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29342176/the-handedness-of-language-directional-symmetry-breaking-of-sign-usage-in-words
#2
Md Izhar Ashraf, Sitabhra Sinha
Language, which allows complex ideas to be communicated through symbolic sequences, is a characteristic feature of our species and manifested in a multitude of forms. Using large written corpora for many different languages and scripts, we show that the occurrence probability distributions of signs at the left and right ends of words have a distinct heterogeneous nature. Characterizing this asymmetry using quantitative inequality measures, viz. information entropy and the Gini index, we show that the beginning of a word is less restrictive in sign usage than the end...
2018: PloS One
https://www.readbyqxmd.com/read/29337998/cognitive-mechanisms-for-inferring-the-meaning-of-novel-signals-during-symbolisation
#3
Justin Sulik
As participants repeatedly interact using graphical signals (as in a game of Pictionary), the signals gradually shift from being iconic (or motivated) to being symbolic (or arbitrary). The aim here is to test experimentally whether this change in the form of the signal implies a concomitant shift in the inferential mechanisms needed to understand it. The results show that, during early, iconic stages, there is more reliance on creative inferential processes associated with insight problem solving, and that the recruitment of these cognitive mechanisms decreases over time...
2018: PloS One
https://www.readbyqxmd.com/read/29325914/micro-cultural-customization-of-organ-donation-propagation-messages
#4
Anke Dunkel, Kent Nakamoto, Peter J Schulz
OBJECTIVE: Organ transplantation is plagued by limited availability of organs. This study investigated the effect of messages promoting organ donation which were customized according to the language-defined micro-cultures in Switzerland. METHODS: Community-, informative-, and emotional-oriented messages were carried by conventional flyers. A 3 × 3 between-subjects experiment was conducted with short- and long-term willingness to donate, long-term signing of organ donation card and long-term interpersonal communication on organ donation as outcome variables...
December 29, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/29324567/electronic-health-record-implementation-findings-at-a-large-suburban-health-and-human-services-department
#5
Kenyon Crowley, Anubhuti Mishra, Raul Cruz-Cano, Robert Gold, Dushanka Kleinman, Ritu Agarwal
OBJECTIVE: Evaluate an electronic health record (EHR) implementation across a large public health department to better understand and improve implementation effectiveness of EHRs in public health departments. DESIGN: A survey based on Consolidated Framework for Implementation Research constructs was administered to staff before and after implementation of an EHR. SETTING: Large suburban county department of health and human services that provides clinical, behavioral, social, and oral health services...
January 10, 2018: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/29324475/bilateral-cochlear-implants-maximizing-expected-outcomes
#6
Kate E Willis, Nathan J Blum, Stephanie A Waryasz, Marilyn Augustyn
Sonia is a 4 1/12-year-old girl with Waardenburg syndrome and bilateral sensorineural hearing loss who had bilateral cochlear implants at 2 7/12 years of age. She is referred to Developmental-Behavioral Pediatrics by her speech/language pathologist because of concerns that her language skills are not progressing as expected after the cochlear implant. At the time of the implant, she communicated using approximately 20 signs and 1 spoken word (mama). At the time of the evaluation (18 months after the implant) she had approximately 70 spoken words (English and Spanish) and innumerable signs that she used to communicate...
January 10, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29320883/the-prevalence-of-oral-stage-dysphagia-in-adults-presenting-with-temporomandibular-disorders-a-systematic-review-and-meta-analysis
#7
Órla Gilheaney, Sibylle Béchet, Patrick Kerr, Ciaran Kenny, Shauna Smith, Rita Kouider, Rachel Kidd, Margaret Walshe
OBJECTIVE: Temporomandibular disorders (TMDs) are the most commonly experienced non-dental orofacial pain disorders, with pain and dysfunction potentially resulting in oral stage dysphagia (OD). However, limited research has been conducted on this condition, with potential negative effects on clinical practice. Therefore, the aim of this study was to determine the prevalence of OD in adults presenting with TMDs, diagnosed as per the Research Diagnostic Criteria for Temporomandibular Disorders or the Diagnostic Criteria for Temporomandibular Disorders protocols...
January 11, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29320216/legibility-of-text-and-pictograms-in-variable-message-signs-can-single-word-messages-outperform-pictograms
#8
Javier Roca, Beatriz Insa, Pilar Tejero
OBJECTIVE: The current research shows the advantage of single-word messages in the particular case of variable message signs (VMSs) with a high aspect ratio. BACKGROUND: Early studies on traffic sign design proposed that pictorial information would advantage equivalent text messages in static signs. METHOD: We used a driving simulator to present individually 36 VMSs, showing six words (e.g., "congestion") and six danger signs (e.g., congestion traffic sign)...
January 1, 2018: Human Factors
https://www.readbyqxmd.com/read/29320155/transparent-and-waterproof-ionic-liquids-based-fibers-for-highly-durable-multifunctional-sensors-and-strain-insensitive-stretchable-conductors
#9
Song Chen, Haizhou Liu, Shuqi Liu, Pingping Wang, Songshan Zeng, Luyi Sun, Lan Liu
Ionic liquids (ILs) are regarded as ideal components in the next generation of strain sensors because their ultralow modulus can commendably circumvent or manage the mechanical mismatch in traditional strain sensors. In addition to strain sensors, stretchable conductors with strain-insensitive conductance are also indispensable in artificial systems for connecting and transporting electrons, similar to the function of blood vessels in the human body. In this work, two types of ILs-based conductive fibers were fabricated by developing hollow fibers with specific micro-scale channels which were then filled with ILs...
January 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29315488/towards-an-international-language-for-incontinence-associated-dermatitis-iad-design-and-evaluation-of-psychometric-properties-of-the-ghent-global-iad-categorisation-tool-globiad-in-30-countries
#10
D Beeckman, K Van den Bussche, P Alves, M C Arnold Long, H Beele, G Ciprandi, F Coyer, T de Groot, D De Meyer, E Deschepper, A M Dunk, A Fourie, P García-Molina, M Gray, A Iblasi, R Jelnes, E Johansen, A Karadağ, K Leblanc, Z Kis Dadara, S Meaume, A Pokorna, M Romanelli, S Ruppert, L Schoonhoven, S Smet, C Smith, A Steininger, M Stockmayr, N Van Damme, D Voegeli, A Van Hecke, S Verhaeghe, K Woo, J Kottner
BACKGROUND: Incontinence-associated dermatitis (IAD) is a specific type of irritant contact dermatitis with different levels of severity. An internationally accepted instrument to assess the severity of IAD in adults with established diagnostic accuracy, agreement, and reliability is needed to support clinical practice and research. OBJECTIVES: To design and psychometrically evaluate the Ghent Global IAD Categorisation Tool (GLOBIAD). METHODS: The design was based on expert consultation using a three-round Delphi procedure with 34 experts from 13 countries...
January 8, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29306849/verbal-learning-and-memory-outcome-in-selective-amygdalohippocampectomy-versus-temporal-lobe-resection-in-patients-with-hippocampal-sclerosis
#11
Mette Thrane Foged, Kirsten Vinter, Louise Stauning, Troels W Kjær, Brice Ozenne, Sándor Beniczky, Olaf B Paulson, Flemming Find Madsen, Lars H Pinborg
PURPOSE: With the advent of new very selective techniques like thermal laser ablation to treat drug-resistant focal epilepsy, the controversy of resection size in relation to seizure outcome versus cognitive deficits has gained new relevance. The purpose of this study was to test the influence of the selective amygdalohippocampectomy (SAH) versus nonselective temporal lobe resection (TLR) on seizure outcome and cognition in patients with mesial temporal lobe epilepsy (MTLE) and histopathological verified hippocampal sclerosis (HS)...
January 4, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29305643/treatment-of-soft-tissue-filler-complications-expert-consensus-recommendations
#12
REVIEW
Fernando Urdiales-Gálvez, Nuria Escoda Delgado, Vitor Figueiredo, José V Lajo-Plaza, Mar Mira, Antonio Moreno, Francisco Ortíz-Martí, Rosa Del Rio-Reyes, Nazaret Romero-Álvarez, Sofía Ruiz Del Cueto, María A Segurado, Cristina Villanueva Rebenaque
BACKGROUND: Dermal fillers have been increasingly used in minimally invasive facial esthetic procedures. This widespread use has led to a rise in reports of associated complications. The aim of this expert consensus report is to describe potential adverse events associated with dermal fillers and to provide guidance on their treatment and avoidance. METHODS: A multidisciplinary group of experts in esthetic treatments convened to discuss the management of the complications associated with dermal fillers use...
January 5, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29304812/the-cradle-vital-signs-alert-qualitative-evaluation-of-a-novel-device-designed-for-use-in-pregnancy-by-healthcare-workers-in-low-resource-settings
#13
Hannah L Nathan, Helena Boene, Khatia Munguambe, Esperança Sevene, David Akeju, Olalekan O Adetoro, Umesh Charanthimath, Mrutyunjaya B Bellad, Annemarie de Greeff, John Anthony, David R Hall, Wilhelm Steyn, Marianne Vidler, Peter von Dadelszen, Lucy C Chappell, Jane Sandall, Andrew H Shennan
BACKGROUND: Vital signs measurement can identify pregnant and postpartum women who require urgent treatment or referral. In low-resource settings, healthcare workers have limited access to accurate vital signs measuring devices suitable for their environment and training. The CRADLE Vital Signs Alert (VSA) is a novel device measuring blood pressure and pulse that is accurate in pregnancy and designed for low-resource settings. Its traffic light early warning system alerts healthcare workers to the need for escalation of care for women with hypertension, haemorrhage or sepsis...
January 5, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29304183/white-matter-alterations-in-parkinson-s-disease-with-normal-cognition-precede-grey-matter-atrophy
#14
Ivan Rektor, Alena Svátková, Lubomir Vojtíšek, Iva Zikmundová, Jirí Vaníček, András Király, Nikoletta Szabó
INTRODUCTION: While progressive MRI brain changes characterize advanced Parkinson's disease (PD), little has been discovered about structural alterations in the earliest phase of the disease, i.e. in patients with motor symptoms and with normal cognition. Our study aimed to detect grey matter (GM) and white matter (WM) changes in PD patients without cognitive impairment. METHODS: Twenty PD patients and twenty-one healthy controls (HC) were tested for attention, executive function, working memory, and visuospatial and language domains...
2018: PloS One
https://www.readbyqxmd.com/read/29301613/testing-olfactory-function-and-mapping-the-structural-olfactory-networks-in-the-brain
#15
Alexander Fjældstad
We perceive the world through our senses. The dependence on these sensory stimuli becomes obvious when we see a visually impaired individual with a guide dog or an individual using sign language. However, individuals with olfactory deficits suffer from a more concealed impairment without any opportunity for diagnostics or treatment in the Danish healthcare system. Around a fifth of the population experience olfactory deficits, of which 1-2% are functionally anosmic. The personal consequences for anosmics can be extensive, lacking not only in hedonic yield related to eating and drinking, but also the socialization during dinners can become niggling...
January 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29298164/neural-activity-during-mental-rotation-in-deaf-signers-the-influence-of-long-term-sign-language-experience
#16
Hong-Bo Le, Hui-Hong Zhang, Qiu-Lin Wu, Jiong Zhang, Jing-Jing Yin, Shu-Hua Ma
OBJECTIVES: Mental rotation is the brain's visuospatial understanding of what objects are and where they belong. Previous research indicated that deaf signers showed behavioral enhancement for nonlinguistic visual tasks, including mental rotation. In this study, we investigated the neural difference of mental rotation processing between deaf signers and hearing nonsigners using blood oxygen level-dependent (BOLD) functional magnetic resonance imaging (fMRI). DESIGN: The participants performed a block-designed experiment, consisting of alternating blocks of comparison and rotation periods, separated by a baseline or fixation period...
January 2, 2018: Ear and Hearing
https://www.readbyqxmd.com/read/29291254/supportive-periodontal-therapy-spt-for-maintaining-the-dentition-in-adults-treated-for-periodontitis
#17
REVIEW
Carolina Manresa, Elena C Sanz-Miralles, Joshua Twigg, Manuel Bravo
BACKGROUND: Periodontitis is a bacterially-induced, chronic inflammatory disease that destroys the connective tissues and bone that support teeth. Active periodontal treatment aims to reduce the inflammatory response, primarily through eradication of bacterial deposits. Following completion of treatment and arrest of inflammation, supportive periodontal therapy (SPT) is employed to reduce the probability of re-infection and progression of the disease; to maintain teeth without pain, excessive mobility or persistent infection in the long term, and to prevent related oral diseases...
January 1, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29280684/sport-related-concussive-convulsions-a-systematic-review
#18
Nicholas O Kuhl, Aaron M Yengo-Kahn, Hannah Burnette, Gary S Solomon, Scott L Zuckerman
OBJECTIVES: The incidence of sport-related concussion (SRC) continues to rise. Presentations of concussed athletes vary from subtle symptoms to notable signs. Between the 4th and 5th iterations of the Concussion in Sport Group (CISG) guidelines, concussive convulsions were removed as a modifying factor, but little evidence or discussion supported this change. While considerable research exists regarding post-traumatic epilepsy in moderate to severe traumatic brain injury, convulsions following SRC are relatively understudied...
December 27, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29280475/the-comparative-efficacy-and-safety-of-sugammadex-and-neostigmine-in-reversing-neuromuscular-blockade-in-adults-a-cochrane-systematic-review-with-meta-analysis-and-trial-sequential-analysis
#19
REVIEW
A-M Hristovska, P Duch, M Allingstrup, A Afshari
We compared the efficacy and safety of sugammadex and neostigmine in reversing neuromuscular blockade in adults. Our outcomes were: recovery time from second twitch to train-of-four ratio > 0.9; recovery time from post-tetanic count 1-5 to train-of-four ratio > 0.9; and risk of composite adverse and serious adverse events. We searched for randomised clinical trials irrespective of publication status and date, blinding status, outcomes reported or language. We included 41 studies with 4206 participants...
December 27, 2017: Anaesthesia
https://www.readbyqxmd.com/read/29276778/maternal-factors-associated-with-early-childhood-caries-in-urban-latino-children
#20
T Tiwari, A R Wilson, M Mulvahill, N Rai, J Albino
The objective of this investigation was to describe maternal psychosocial, behavioral, and acculturation factors associated with early childhood caries in a sample of urban Latino mother-child dyads. A cross-sectional survey was conducted with 100 mothers whose children (under the age of 6 y) were patients at the Dental Center at Children's Hospital Colorado in Aurora, Colorado. All children participating in the study received an oral examination to measure decayed, missing, filled, surfaces (dmfs). Participating mothers were given the option to sign the consent form and complete the survey in English or Spanish, according to their preferred language...
January 2018: JDR Clinical and Translational Research
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