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https://www.readbyqxmd.com/read/28338664/characteristics-of-non-vitreoretinal-ocular-injury-in-child-maltreatment-a-systematic-review
#1
T Betts, S Ahmed, S Maguire, P Watts
PurposeTo identify the spectrum of non-vitreoretinal ocular injury due to child maltreatment.MethodsAll language search of MEDLINE, PsychINFO, EMBASE, AMED, Web of Science, and CINAHL databases, 1950-2015, was conducted. INCLUSION CRITERIA: explicit confirmation of injury aetiology, age <18 years, examination conducted by an ophthalmologist. Exclusion: post-mortem data, organic diseases, review articles. Standardised critical appraisal and narrative synthesis was conducted of included publications by two independent reviewers...
March 24, 2017: Eye
https://www.readbyqxmd.com/read/28333506/language-switching-across-modalities-evidence-from-bimodal-bilinguals
#2
Patricia Dias, Saúl Villameriel, Marcel R Giezen, Brendan Costello, Manuel Carreiras
This study investigated whether language control during language production in bilinguals generalizes across modalities, and to what extent the language control system is shaped by competition for the same articulators. Using a cued language-switching paradigm, we investigated whether switch costs are observed when hearing signers switch between a spoken and a signed language. The results showed an asymmetrical switch cost for bimodal bilinguals on reaction time (RT) and accuracy, with larger costs for the (dominant) spoken language...
March 23, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28328102/sound-symbolism-the-role-of-word-sound-in-meaning
#3
REVIEW
Jan-Olof Svantesson
The question whether there is a natural connection between sound and meaning or if they are related only by convention has been debated since antiquity. In linguistics, it is usually taken for granted that 'the linguistic sign is arbitrary,' and exceptions like onomatopoeia have been regarded as marginal phenomena. However, it is becoming more and more clear that motivated relations between sound and meaning are more common and important than has been thought. There is now a large and rapidly growing literature on subjects as ideophones (or expressives), words that describe how a speaker perceives a situation with the senses, and phonaesthemes, units like English gl-, which occur in many words that share a meaning component (in this case 'light': gleam, glitter, etc...
March 22, 2017: Wiley Interdisciplinary Reviews. Cognitive Science
https://www.readbyqxmd.com/read/28299405/validation-of-the-international-consultation-on-incontinence-questionnaire-vaginal-symptoms-iciq-vs-in-two-south-asian-languages
#4
Chanil D Ekanayake, Arunasalam Pathmeswaran, Rasika P Herath, H Suharshi S Perera, Malitha Patabendige, Prasantha S Wijesinghe
INTRODUCTION: The multifaceted nature of pelvic floor disorders means that a systematic evaluation is required for optimal treatment outcome. It is also generally acknowledged that a valid tool is necessary to objectively assess symptoms reported by affected women. METHODS: The International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS) questionnaire was translated to Sinhala and Tamil and a validation study carried out among women attending gynecology clinics at North Colombo Teaching Hospital, Ragama, and the district general hospitals Mannar and Vavuniya...
March 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28299240/validation-of-the-total-visual-acuity-extraction-algorithm-tova-for-automated-extraction-of-visual-acuity-data-from-free-text-unstructured-clinical-records
#5
Douglas M Baughman, Grace L Su, Irena Tsui, Cecilia S Lee, Aaron Y Lee
PURPOSE: With increasing volumes of electronic health record data, algorithm-driven extraction may aid manual extraction. Visual acuity often is extracted manually in vision research. The total visual acuity extraction algorithm (TOVA) is presented and validated for automated extraction of visual acuity from free text, unstructured clinical notes. METHODS: Consecutive inpatient ophthalmology notes over an 8-year period from the University of Washington healthcare system in Seattle, WA were used for validation of TOVA...
March 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28295866/mapping-language-to-the-world-the-role-of-iconicity-in-the-sign-language-input
#6
Pamela Perniss, Jenny C Lu, Gary Morgan, Gabriella Vigliocco
Most research on the mechanisms underlying referential mapping has assumed that learning occurs in ostensive contexts, where label and referent co-occur, and that form and meaning are linked by arbitrary convention alone. In the present study, we focus on iconicity in language, that is, resemblance relationships between form and meaning, and on non-ostensive contexts, where label and referent do not co-occur. We approach the question of language learning from the perspective of the language input. Specifically, we look at child-directed language (CDL) in British Sign Language (BSL), a language rich in iconicity due to the affordances of the visual modality...
March 12, 2017: Developmental Science
https://www.readbyqxmd.com/read/28282763/mirna-expression-for-early-diagnosis-of-preeclampsia-onset-hope-or-hype
#7
Antonio Simone Laganà, Salvatore Giovanni Vitale, Fabrizio Sapia, Gaetano Valenti, Francesco Corrado, Francesco Padula, Agnese Maria Chiara Rapisarda, Rosario D'Anna
PURPOSE: Preeclampsia (PE) is a multi-systemic disease characterized by hypertension, proteinuria and other typical signs that can negatively affect the development of pregnancy. The outcome of the disease is strongly linked to the possibility of early diagnosis, in order to prevent the clinical manifestations. Pathogenesis is still unknown, although abnormalities of placenta development linked to angiogenesis alterations and abnormal trophoblastic invasion seem to be involved, corroborating the epigenetic theory...
March 5, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28282629/manganese-exposure-and-neurotoxic-effects-in-children
#8
REVIEW
Geir Bjørklund, Max Stanley Chartrand, Jan Aaseth
Manganese (Mn) is the fifth most abundant metal on earth. Although it is a well understood essential trace element, in excess, Mn is neurotoxic. Initial toxic symptoms associated with Mn are of psychiatric nature and are clinically defined as locura manganica. Neurological signs of Mn toxicity include dystonia, progressive bradykinesia, and disturbance of gait, slurring, and stuttering of speech with diminished volume. Studies indicate that children who ingested Mn in the drinking water (WMn) at or above a level of 0...
March 7, 2017: Environmental Research
https://www.readbyqxmd.com/read/28280057/discourses-of-prejudice-in-the-professions-the-case-of-sign-languages
#9
Tom Humphries, Poorna Kushalnagar, Gaurav Mathur, Donna Jo Napoli, Carol Padden, Christian Rathmann, Scott Smith
There is no evidence that learning a natural human language is cognitively harmful to children. To the contrary, multilingualism has been argued to be beneficial to all. Nevertheless, many professionals advise the parents of deaf children that their children should not learn a sign language during their early years, despite strong evidence across many research disciplines that sign languages are natural human languages. Their recommendations are based on a combination of misperceptions about (1) the difficulty of learning a sign language, (2) the effects of bilingualism, and particularly bimodalism, (3) the bona fide status of languages that lack a written form, (4) the effects of a sign language on acquiring literacy, (5) the ability of technologies to address the needs of deaf children and (6) the effects that use of a sign language will have on family cohesion...
March 9, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28274325/consent-for-the-diagnosis-of-preclinical-dementia-states-a-review
#10
REVIEW
Julian C Hughes, Thomas A Ingram, Aron Jarvis, Elise Denton, Zoe Lampshire, Cathy Wernham
It is now possible to detect the pathology of Alzheimer's disease (AD) many years before symptoms and signs otherwise become manifest. Biomarkers of disease include evidence of amyloid and tau in the cerebrospinal fluid and neuroimaging which (for instance) allows amyloid in the brain to be visualized. There is, thus, a preclinical state in which it is possible to identify Alzheimer's pathology long before there is clinical evidence of disease. Much research focuses on this preclinical state because it seems likely that treatments will be more effective before the disease is established...
April 2017: Maturitas
https://www.readbyqxmd.com/read/28273133/postoperative-pain-treatment-after-total-knee-arthroplasty-a-systematic-review
#11
Anders Peder Højer Karlsen, Mik Wetterslev, Signe Elisa Hansen, Morten Sejer Hansen, Ole Mathiesen, Jørgen B Dahl
INTRODUCTION: The aim of this systematic review was to document efficacy, safety and quality of evidence of analgesic interventions after total knee arthroplasty (TKA). METHODS: This PRISMA-compliant and PROSPERO-registered review includes all-language randomized controlled trials of medication-based analgesic interventions after TKA. Bias was evaluated according to Cochrane methodology. Outcomes were opioid consumption (primary), pain scores at rest and during mobilization, adverse events, and length of stay...
2017: PloS One
https://www.readbyqxmd.com/read/28273042/bioadvance-patient-support-program-survey-positive-perception-of-intravenous-infusions-of-inflixmab
#12
(no author information available yet)
PURPOSE: To understand the perception of intravenous infusions in patients receiving infliximab (Remicade) within the BioAdvance patient support program (PSP). DESIGN: Intravenous infusion of infliximab occurs at approximately 200 clinics across Canada and is managed via the BioAdvance PSP. Patients were invited to complete a 28-question survey on demographics, disease/treatment characteristics, health rating, lifestyle, employment, and perception of intravenous infusions and the BioAdvance program...
February 2017: Managed Care
https://www.readbyqxmd.com/read/28268838/visualizing-patient-journals-by-combining-vital-signs-monitoring-and-natural-language-processing
#13
Adnan Vilic, John Asger Petersen, Karsten Hoppe, Helge B D Sorensen
This paper presents a data-driven approach to graphically presenting text-based patient journals while still maintaining all textual information. The system first creates a timeline representation of a patients' physiological condition during an admission, which is assessed by electronically monitoring vital signs and then combining these into Early Warning Scores (EWS). Hereafter, techniques from Natural Language Processing (NLP) are applied on the existing patient journal to extract all entries. Finally, the two methods are combined into an interactive timeline featuring the ability to see drastic changes in the patients' health, and thereby enabling staff to see where in the journal critical events have taken place...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28261876/retraction
#14
(no author information available yet)
Retraction: "Chronic NMDA administration to rats up-regulates frontal cortex cytosolic phospholipase A2 and its transcription factor, activator protein-2" by Rao JS, Ertley RN, Rapoport SI, Bazinet RP, Lee HJ. The above article from Journal of Neurochemistry, published online on 13 April 2007 in Wiley Online Library (wileyonlinelibrary.com) and in volume 102, issue 6, pp. 1918-1927, has been retracted by agreement between the corresponding author Stanley Rapoport, co-author Richard Bazinet, the Journal's Editor-in-Chief Jörg Schulz, and John Wiley & Sons Ltd...
March 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28261875/retraction
#15
(no author information available yet)
Retraction: "Aging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex" by Keleshian VL, Modi HR, Rapoport SI, Rao JS. The above article from Journal of Neurochemistry, published online on 17 February 2013 in Wiley Online Library (wileyonlinelibrary.com) and in volume 121, issue 1, pp. 63-73, has been retracted by agreement between the corresponding author Stanley Rapoport, the Journal's Editor-in-Chief, Jörg Schulz, and John Wiley & Sons Ltd...
March 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28256376/-autism-an-early-neurodevelopmental-disorder
#16
F Bonnet-Brilhault
With approximately 67 million individuals affected worldwide, autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder (United Nations, 2011), with a prevalence estimated to be 1/100. In France ASD affects approximately 600,000 individuals (from childhood to adulthood, half of whom are also mentally retarded), who thus have a major handicap in communication and in adapting to daily life, which leads autism to be recognized as a national public health priority. ASD is a neurodevelopmental disorder that affects several domains (i...
April 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28251848/highly-sensitive-textile-strain-sensors-and-wireless-user-interface-devices-using-all-polymeric-conducting-fibers
#17
Jimi Eom, Rawat Jaisutti, Hyungseok Lee, Woobin Lee, Jae-Sang Heo, Jun-Young Lee, Sung Kyu Park, Yong-Hoon Kim
Emulation of diverse electronic devices on textile platform is considered as a promising approach for implementing wearable smart electronics. Of particular, the development of multifunctional polymeric fibers and their integration in common fabrics have been extensively researched for human friendly wearable platforms. Here we report a successful emulation of multifunctional body-motion sensors and user-interface (UI) devices in textile platform by using in situ polymerized poly(3,4-ethylenedioxythiophene) (PEDOT)-coated fibers...
March 22, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28247649/-validation-of-urgency-scale-to-detect-and-assess-urgency-in-patients-with-overactive-bladder
#18
G G Krivoborodov, E I Tur
INTRODUCTION: Urinary urgency is a hallmark symptom of overactive bladder (OAB). Several scales have been used to measure urgency. Taking into account the exceptional importance of these scales, it is important to determine their reliability, which depends directly on the accuracy of the wording and clarity to patients. AIM: To determine reliability of Russian-language translation of the Patient Perception of Intensity of Urgency Scale (PPIUS) in identifying and assessing urgency in patients with OAB...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247238/clinical-pharmacokinetic-monitoring-of-leflunomide-in-renal-transplant-recipients-with-bk-virus-reactivation-a-review-of-the-literature
#19
REVIEW
Joan C Y Ng, Marianna Leung, Alissa J Wright, Mary H H Ensom
Leflunomide is an immunosuppressive drug with in vitro and initial observational evidence of antiviral activity against BK virus (BKV), a pathogen that causes opportunistic infection upon reactivation in renal transplant recipients. Leflunomide is considered an ancillary option to immunosuppression reduction in the management of BKV reactivation. Plasma or blood concentrations of teriflunomide, the active metabolite of leflunomide, are commonly monitored because of high leflunomide doses being used, known inter-individual variability in pharmacokinetics, and hepatotoxicity risk...
February 28, 2017: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/28245347/autologous-serum-eye-drops-for-dry-eye
#20
REVIEW
Qing Pan, Adla Angelina, Michael Marrone, Walter J Stark, Esen K Akpek
BACKGROUND: Theoretically, autologous serum eye drops (AS) offer a potential advantage over traditional therapies on the assumption that AS not only serve as a lacrimal substitute to provide lubrication but contain other biochemical components that allow them to mimic natural tears more closely. Application of AS has gained popularity as second-line therapy for patients with dry eye. Published studies on this subject indicate that autologous serum could be an effective treatment for dry eye...
February 28, 2017: Cochrane Database of Systematic Reviews
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