keyword
MENU ▼
Read by QxMD icon Read
search

Live

keyword
https://www.readbyqxmd.com/read/29471587/managing-unsolicited-findings-in-genomics-a-qualitative-interview-study-with-cancer-patients
#1
R M Bijlsma, R H P Wouters, H Wessels, A M May, M G E M Ausems, E E Voest, A L Bredenoord
OBJECTIVE: Next-generation sequencing (NGS) is increasingly being employed in the context of personalized cancer treatment. Anticipating unsolicited findings that may arise during a NGS procedure is a key consideration; however, little is known about cancer patients' intentions, needs, and preferences concerning the return of unsolicited findings. METHODS: A qualitative design using individual semi-structured interviews with 24 cancer patients was utilized to explore patients' decisions on whether to receive unsolicited findings from NGS...
February 22, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29471575/-breast-cancer-diagnostics-and-therapy-the-most-important-facts-for-internists
#2
Ulrich Hamann, Christine Ankel
LEARNING OBJECTIVES:  After reviewing this article, the participant should be able to: 1. Understand the epidemiology of breast cancer, its incidence and impact. 2. Appreciate the importance of early diagnosis and treatment. 3. Understand the concept of comprehensive breast cancer management and its multidisciplinarity. 4. Be knowledgeable about the entire process required to manage breast cancer, since the early diagnosis until the management of non breast related conditions derived from the treatment...
February 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29471550/phenotype-genotype-correlation-in-children-with-neurofibromatosis-type-1
#3
Christophe Barrea, Sandrine Vaessen, Saskia Bulk, Julie Harvengt, Jean-Paul Misson
Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder with an incidence of ∼1 in 4,000 live births. Neurofibromin, the gene product, is ubiquitously expressed at high levels in the nervous system and functions as a tumor suppressor. Haploinsufficiency of neurofibromin through mutation leads to an increased risk of developing benign and malignant tumors in affected individuals. Although NF1 has complete penetrance, it displays considerable inter- and intrafamilial variability in phenotypic expression which poses disease prediction and management problems...
February 22, 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29471541/the-caucasian-nasal-septum-an-in-vivo-computed-tomography-study
#4
Charles Daultrey, John Hardman, Shahram Anari
Background: The nasal septum is composed of cartilaginous and bony components and an understanding of each component volume is essential in both functional and cosmetic surgery. Objectives: We sought to radiographically measure septal dimensions on cross sectional computer tomography (CT) images, establishing average parameters for normal anatomy among a single, Caucasian population group. Methods: One hundred and fifty consecutive sinus CT scan images were examined and 100 cases with appropriate sagittal views were included in the study...
February 19, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29471523/liver-transcriptomic-and-plasma-metabolomic-profiles-of-fattening-lambs-are-modified-by-feed-restriction-during-the-suckling-period
#5
A Santos, F J Giráldez, E Trevisi, L Lucini, J Frutos, S Andrés
The increasing world population is driving demand for improved efficiency of feed resources of livestock. However, the molecular mechanisms behind various feed efficiency traits and their regulation by nutrition remain poorly understood. Here we aimed to identify differentially expressed (DE) genes in the liver tissues of fattening Merino lambs and differences in metabolites accumulated in plasma to identify modified metabolic pathways as a consequence of milk restriction during the suckling period. Twenty-four male Merino lambs (4...
February 19, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471520/effect-of-exposure-to-second-hand-smoke-from-husbands-on-biochemical-hyperandrogenism-metabolic-syndrome-and-conception-rates-in-women-with-polycystic-ovary-syndrome-undergoing-ovulation-induction
#6
Jian Li, Q Wu, Xiao-Ke Wu, Zhong-Ming Zhou, Ping Fu, Xiu-Hua Chen, Ying Yan, Xin Wang, Zheng-Wang Yang, Wei-Li Li, Elisabet Stener-Victorin, Richard S Legro, Ernest Hung-Yu Ng, Heping Zhang, Ben Willem J Mol, Chi Chiu Wang
STUDY QUESTION: Does second-hand smoke (SHS) exposure from husbands have adverse effects on sex hormones, metabolic profiles, clinical phenotypes and fertility outcomes in women with polycystic ovary syndrome (PCOS) undergoing ovulation induction? SUMMARY ANSWER: SHS exposure is associated with worsened biochemical hyperandrogenism, higher incidence of metabolic syndrome and reduced conception rates in women with PCOS. WHAT IS KNOWN ALREADY: Smoking in women impairs fecundity at some stages of the reproductive process including folliculogenesis, embryo transport, endometrial angiogenesis and uterine blood flow...
February 20, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29471519/higher-risk-of-abdominal-obesity-elevated-ldl-cholesterol-and-hypertriglyceridemia-but-not-of-hypertension-in-people-living-with-hiv-results-from-the-copenhagen-comorbidity-in-hiv-infection-cocomo-study
#7
Marco Gelpi, Shoaib Afzal, Jens Lundgren, Andreas Ronit, Ashley Roen, Amanda Mocroft, Jan Gerstoft, Anne-Mette Lebech, Birgitte Lindegaard, Klaus Fuglsang Kofoed, Børge G Nordestgaard, Susanne Dam Nielsen
Background: People living with HIV (PLWH) have lower life expectancy than uninfected individuals, partly explained by excess risk of cardiovascular diseases (CVD) and CVD risk factors. We investigated the association between HIV infection and abdominal obesity, elevated LDL cholesterol (LDL-C), hypertriglyceridemia and hypertension, in a large cohort of predominantly well-treated PLWH and matched controls. Methods: 1,099 PLWH from the Copenhagen Co-morbidity in HIV infection (COCOMO) study and 12,161 age and sex-matched uninfected controls from the Copenhagen General Population Study were included and underwent blood pressure, waist-, hip-, weight-, and height-measurements...
February 17, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29471481/bacterial-fungal-interactions-ecology-mechanisms-and-challenges
#8
A Deveau, G Bonito, J Uehling, M Paoletti, M Becker, S Bindschedler, S Hacquard, V Hervé, J Labbé, O A Lastovetsky, S Mieszkin, L J Millet, B Vajna, P Junier, P Bonfante, B P Krom, S Olsson, J D van Elsas, L Y Wick
Fungi and bacteria are found living together in a wide variety of environments. Their interactions are significant drivers of many ecosystem functions and are important for the health of plants and animals. A large number of fungal and bacterial families are engaged in complex interactions that lead to critical behavioural shifts of the microorganisms ranging from mutualism to pathogenicity. The importance of bacterial-fungal interactions (BFI) in environmental science, medicine and biotechnology has led to the emergence of a dynamic and multidisciplinary research field that combines highly diverse approaches including molecular biology, genomics, geochemistry, chemical and microbial ecology, biophysics and ecological modelling...
February 19, 2018: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/29471454/the-impact-of-using-different-reference-populations-on-measurement-of-breast-cancer-related-cognitive-impairment-rates
#9
Jonathan D Clapp, George Luta, Brent J Small, Tim A Ahles, James C Root, Deena Graham, Arti Hurria, Paul B Jacobsen, Heather Jim, Brenna C McDonald, Robert A Stern, Andrew J Saykin, Jeanne S Mandelblatt
Objective: To evaluate how use of different reference populations affects estimates of breast cancer-related cognitive impairment rates. Methods: Patients aged ≥60 years with stage 0-3 breast cancer (n = 371) and matched non-cancer controls (n = 370) completed 13 neuropsychological tests prior to systemic therapy or at enrollment (controls). The tests captured three domains: attention, processing speed and executive function; learning and memory; and visual-spatial function...
February 17, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29471451/genomic-evidence-of-widespread-admixture-from-polar-bears-into-brown-bears-during-the-last-ice-age
#10
James A Cahill, Peter D Heintzman, Kelley Harris, Matthew D Teasdale, Joshua Kapp, André E Rodrigues Soares, Ian Stirling, Daniel Bradley, Ceiridwen J Edwards, Kiley Graim, Aliaksandr A Kisleika, Alexander V Malev, Nigel Monaghan, Richard E Green, Beth Shapiro
Recent genomic analyses have provided substantial evidence for past periods of gene flow from polar bears (Ursus maritimus) into Alaskan brown bears (Ursus arctos), with some analyses suggesting a link between climate change and genomic introgression. However, because it has mainly been possible to sample bears from the present day, the timing, frequency, and evolutionary significance of this admixture remains unknown. Here, we analyze genomic DNA from three additional and geographically distinct brown bear populations, including two that lived temporally close to the peak of the last ice age...
February 20, 2018: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/29471443/board-invited-review-immunomodulatory-potential-of-dietary-soybean-derived-isoflavones-and-saponins-in-pigs
#11
B N Smith, R N Dilger
In this review, the potential for use of soy-derived bioactive compounds as immunomodulatory feed additives in pigs is discussed. Soy is a major component of the modern U.S. swine diet in today's commercial industry, providing the bulk of dietary AA necessary for growth and production. However, soy use has generally been limited in early growth phases, during which the risks of immunological insult and disease are among the highest. Improvements of soybean processing and development of soy protein products with little to no antinutritional factors have made soy more appropriate for use in young pigs but additional processing may impact bioactive compound levels in the feed...
February 17, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29471427/health-and-work-in-women-and-men-in-the-welding-and-electrical-trades-how-do-they-differ
#12
Nicola Cherry, Victoria Arrandale, Jeremy Beach, Jean-Michel F Galarneau, Antonia Mannette, Laura Rodgers
Objectives: There is little information on how work tasks, demands, and exposures differ between women and men in nominally the same job. This is critical in setting workplace standards that will protect the health of both men and those women moving into less traditional work roles. Information used in setting standards is currently based almost entirely on male workers. This paper describes differences in work and health, and the relation between them, in women and men who have undergone the same trade training for the welding or electrical trades...
February 17, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29471420/ethics-effectiveness-and-population-health-information-interventions-a-canadian-analysis
#13
Devon Greyson, Rod Knight, Jean A Shoveller
Population health information interventions (PHIIs) use information in efforts to promote health. PHIIs may push information to a target audience (communication), pull information from the public (surveillance), or combine both in a bidirectional intervention. Although PHIIs have often been framed as non-invasive and ethically innocuous, in reality they may be intrusive into people's lives, affecting not only their health but their senses of security, respect, and self-determination. Ethical acceptability of PHIIs may have impacts on intervention effectiveness, potentially giving rise to unintended consequences...
February 19, 2018: Health Promotion International
https://www.readbyqxmd.com/read/29471366/loss-of-trust-in-the-neighborhood-the-experience-of-older-african-americans-in-detroit
#14
Heather Fritz, Malcolm P Cutchin, Emily R Cummins
Objective: Although evidence suggests that neighborhood conditions are related to stress and health, the processes connecting neighborhood conditions and stress for older minorities is little explored. The purpose of this analysis is to contribute new insights into this issue. Method: We conducted a qualitative analysis as part of a larger mixed methods study of 100 African Americans aged 55 and older living in neighborhoods of varying quality in Detroit, Michigan...
February 19, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29471364/association-of-early-and-adult-life-socioeconomic-circumstances-with-muscle-strength-in-older-age
#15
Boris Cheval, Matthieu P Boisgontier, Dan Orsholits, Stefan Sieber, Idris Guessous, Rainer Gabriel, Silvia Stringhini, David Blane, Bernadette W A van der Linden, Matthias Kliegel, Claudine Burton-Jeangros, Delphine S Courvoisier, Stéphane Cullati
Background: socioeconomic circumstances (SEC) during a person's lifespan influence a wide range of health outcomes. However, solid evidence of the association of early- and adult-life SEC with health trajectories in ageing is still lacking. This study assessed whether early-life SEC are associated with muscle strength in later life-a biomarker of health-and whether this relationship is caused by adult-life SEC and health behaviours. Methods: we used data from the Survey of Health Ageing and Retirement in Europe, a 12-year population-based cohort study with repeated measurement in six waves (2004-15) and retrospective collection of life-course data...
February 20, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29471362/changes-in-hospital-bond-ratings-after-the-transition-to-a-new-electronic-health-record
#16
Dustin McEvoy, Michael L Barnett, Dean F Sittig, Skye Aaron, Ateev Mehrotra, Adam Wright
Objective: To assess the impact of electronic health record (EHR) implementation on hospital finances. Materials and Methods: We analyzed the impact of EHR implementation on bond ratings and net income from service to patients (NISP) at 32 hospitals that recently implemented a new EHR and a set of controls. Results: After implementing an EHR, 7 hospitals had a bond downgrade, 7 had a bond upgrade, and 18 had no changes. There was no difference in the likelihood of bond rating changes or in changes to NISP following EHR go-live when compared to control hospitals...
February 20, 2018: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/29471351/viability-of-campylobacter-spp-in-frozen-and-chilled-broiler-carcasses-according-to-real-time-pcr-with-propidium-monoazide-pretreatment
#17
Andréa G S A Castro, Elaine M S Dorneles, Ethiene L S Santos, Telma M Alves, Guilherme R Silva, Tadeu C Figueiredo, Débora C S Assis, Andrey P Lage, Silvana V Cançado
The aim of this study was to evaluate the viability of Campylobacter spp. in frozen and chilled broiler carcasses using real-time PCR with propidium monoazide (PMA) pretreatment. Sixty broiler carcasses were collected: 30 frozen and 30 chilled. Each carcass was submitted to 2 real-time PCR protocols to detect and quantify Campylobacter spp.: one using pretreatment with PMA, which blocks the amplification of DNA from dead bacteria, and the other without PMA. The results showed that PMA-pretreated carcasses, either frozen or chilled, had a lower positivity rate compared to untreated samples (P < 0...
February 19, 2018: Poultry Science
https://www.readbyqxmd.com/read/29471335/after-70-years-of-fighting-an-age-old-scourge-onchocerciasis-in-uganda-the-end-is-in-sight
#18
Moses N Katabarwa, Thomson Lakwo, Peace Habomugisha, Thomas R Unnasch, Rolf Garms, Lauri Hudson-Davis, Edson Byamukama, Annet Khainza, Johnson Ngorok, Edridah Tukahebwa, Frank O Richards
Onchocerciasis causes severe itching, serious skin disease and ocular damage leading to visual impairment or permanent blindness. It is associated with hanging groin, epilepsy, Nakalanga dwarfism and, most recently, nodding disease. This disease affected communities in 17 transmission foci in 37 districts of Uganda, where about 6.7 million people are once at risk. The efforts against onchocerciasis in Uganda commenced in the late 1940s, when vector control was launched using dichlorodiphenyltrichloroethane; by 1973, Simulium damnosum had been eliminated in the Victoria focus...
March 1, 2018: International Health
https://www.readbyqxmd.com/read/29471320/cover-crop-species-and-management-influence-predatory-arthropods-and-predation-in-an-organically-managed-reduced-tillage-cropping-system
#19
Ariel N Rivers, Christina A Mullen, Mary E Barbercheck
Agricultural practices affect arthropod communities and, therefore, have the potential to influence the activities of arthropods. We evaluated the effect of cover crop species and termination timing on the activity of ground-dwelling predatory arthropods in a corn-soybean-wheat rotation in transition to organic production in Pennsylvania, United States. We compared two cover crop treatments: 1) hairy vetch (Vicia villosa Roth) planted together with triticale (×Triticosecale Wittmack) after wheat harvest, and 2) cereal rye (Secale cereale Linnaeus) planted after corn harvest...
January 29, 2018: Environmental Entomology
https://www.readbyqxmd.com/read/29471248/using-structured-light-three-dimensional-surface-scanning-on-living-individuals-key-considerations-and-best-practice-for-forensic-medicine
#20
Awatif Shamata, Tim Thompson
Non-contact three-dimensional (3D) surface scanning methods have been applied to forensic medicine to record injuries and to mitigate ordinary photography shortcoming. However, there are no literature concerning practical guidance for 3D surface scanning of live victims. This paper aimed to investigate key 3D scanning issues of the live body to develop a series of scanning principles for future use on injured victims. The Pico Scan 3D surface scanner was used on live test subjects. The work focused on analysing the following concerns: (1) an appropriate 3D scanning technique to scan different body areas, (2) the ideal number of scans, (3) scanning approaches to access various areas of the body and (4) elimination of environmental background noise in the acquired data...
February 15, 2018: Journal of Forensic and Legal Medicine
keyword
keyword
5172
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"