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https://www.readbyqxmd.com/read/29451942/incidence-of-and-risk-factors-for-knee-collateral-ligament-injuries-with-proximal-tibia-fractures-a-study-of-32-441-patients
#1
Andre M Samuel, Pablo J Diaz-Collado, Lauren K Szolomayer, Daniel H Wiznia, Wayne W Chan, Adam M Lukasiewicz, Bryce A Basques, Daniel D Bohl, Jonathan N Grauer
Proximal tibia fractures are associated with concurrent collateral ligament injuries. Failure to recognize these injuries may lead to chronic knee instability. The purpose of this study was to identify risk factors for concurrent collateral ligament injuries with proximal tibia fractures and their association with inpatient outcomes. A total of 32,441 patients with proximal tibia fractures were identified in the 2011-2012 National Trauma Data Bank. A total of 1445 (4.5%) had collateral ligament injuries, 794 (2...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29444703/whole-bone-testing-in-small-animals-systematic-characterization-of-the-mechanical-properties-of-different-rodent-bones-available-for-rat-fracture-models
#2
Peter M Prodinger, Peter Foehr, Dominik Bürklein, Oliver Bissinger, Hakan Pilge, Kilian Kreutzer, Rüdiger von Eisenhart-Rothe, Thomas Tischer
OBJECTIVES: Rat fracture models are extensively used to characterize normal and pathological bone healing. Despite, systematic research on inter- and intra-individual differences of common rat bones examined is surprisingly not available. Thus, we studied the biomechanical behaviour and radiological characteristics of the humerus, the tibia and the femur of the male Wistar rat-all of which are potentially available in the experimental situation-to identify useful or detrimental biomechanical properties of each bone and to facilitate sample size calculations...
February 14, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29443862/red-tides-mass-casualty-and-whole-blood-at-sea-red-tides
#3
Benjamin T Miller, Andrew H Lin, Susan C Clark, Andrew P Cap, Joseph J Dubose
BACKGROUND: The U.S. Navy's casualty-receiving ships provide remote damage control resuscitation (RDCR) platforms to treat injured combatants deployed afloat and ashore. We report a significant mass casualty incident aboard the USS Bataan, and the most warm fresh whole blood (WFWB) transfused at sea for traumatic hemorrhagic shock since the Vietnam War. METHODS: Casualty-receiving ships have robust medical capabilities, including a frozen blood bank with packed red blood cells (pRBC) and fresh frozen plasma (FFP)...
February 13, 2018: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29440906/percutaneous-autologous-bone-marrow-transplantation-for-the-treatment-of-delayed-union-of-limb-bone-in-children
#4
Jun Wu, Hongxi Guo, Xing Liu, Ming Li, Yujiang Cao, Xiangyang Qu, Hai Zhou, Liuqi Weng
Background and purpose: Percutaneous autologous bone marrow transplantation (PABMT) is a minimally invasive therapeutic strategy for the treatment of delayed bone union in adults, which has been confirmed by many studies. However, there is no report on PABMT application in pediatric orthopedic surgery. The aim of this article was to analyze the therapeutic effect of PABMT in children with delayed union of limb bone and its influence in relation to delayed bone union therapy, transplantation period, patients' sex, fracture location, and fracture fixation...
2018: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29439698/a-retrospective-analysis-of-bone-mineral-status-in-patients-requiring-spinal-surgery
#5
Tobias Schmidt, Katharina Ebert, Tim Rolvien, Nicola Oehler, Jens Lohmann, Luca Papavero, Ralph Kothe, Michael Amling, Florian Barvencik, Haider Mussawy
BACKGROUND: Impaired bone quality is associated with poor outcome of spinal surgery. The aim of the study was to assess the bone mineral status of patients scheduled to undergo spinal surgery and to report frequencies of bone mineral disorders. METHODS: We retrospectively analyzed the bone mineral status of 144 patients requiring spinal surgery including bone mineral density by dual-energy X-ray absorptiometry (DXA) as well as laboratory data with serum levels of 25-hydroxyvitamin D (25-OH-D), parathyroid hormone, calcium, bone specific alkaline phosphate, osteocalcin, and gastrin...
February 13, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29435659/teenagers-and-young-adults-with-nephropathic-cystinosis-display-significant-bone-disease-and-cortical-impairment
#6
Aurélia Bertholet-Thomas, Debora Claramunt-Taberner, Ségolène Gaillard, Georges Deschênes, Elisabeth Sornay-Rendu, Pawel Szulc, Martine Cohen-Solal, Solenne Pelletier, Marie-Christine Carlier, Pierre Cochat, Justine Bacchetta
BACKGROUND: Bone impairment appears to be a novel complication of nephropathic cystinosis despite cysteamine therapy. Its exact underlying pathophysiology is nevertheless unclear. The objective of this study was to evaluate bone status among patients included in the French Crystobs study. METHODS: In addition to clinical data, bone status was evaluated using biomarkers (ALP, PTH, 25-D, 1-25D, FGF23), DXA (spine and total body), and high-resolution peripheral quantitative computed tomography (HR-pQCT) at the tibia and radius...
February 12, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29432320/segmental-tibia-fractures-an-analysis-of-complication-and-healing-rates
#7
Robert M Corey, Nathan K Park, Lisa K Cannada
OBJECTIVES: To determine the most commonly associated injuries, complications, and healing rates of patients sustaining segmental tibial shaft fractures. DESIGN: Retrospective review. SETTING: Two Level I trauma centers. PATIENTS: One hundred and eight patients with segmental tibial shaft fractures were identified between 2005-2013. INTERVENTION: None. MAIN OUTCOME MEASURES: Demographics, injury characteristics, treatments, and complications...
January 24, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29427092/treatment-of-tibial-nonunion-with-bone-defect-using-a-heterotopic-ossification-as-autologous-bone-graft-literature-overview-and-case-report
#8
REVIEW
Michael Schlumberger, Raul Mayr, Christian Koidl, Martin Eichinger, Tobias Roth
INTRODUCTION: Nonunion after open fracture of the lower leg is a frequent complication with a prevalence of up to 40%. In cases with major bone defects, revision of the osteosynthesis with bone grafting is commonly performed. Until today, there is no report on treatment of a tibial nonunion with transplantation of a heterotopic ossification. PRESENTATION OF CASE: We present a case of a 27-year-old male patient, who suffered from a paragliding accident with major injuries...
February 9, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29424171/-retrograde-interlocked-intramedullary-nailing-with-tibia-bone-graft-fusion-for-the-treatment-of-end-stage-ankle-arthritis
#9
Zhong-Yu Hao, Ping Pei, Lin Liu, Yu-Xin Song
OBJECTIVE: To explore clinical outcomes of retrograde interlocked intramedullary nailing with tibia bone graft fusion in treating end-stage ankle arthritis. METHODS: From November 2014 to April 2016, 22 patients with end-stage ankle arthritis were treated with retrograde interlocked intramedullary nailing with tibia bone graft fusion, including 9 males and 13 females aged from 30 to 65 years old with an average of 48.5 years old. Seven patients had obvious varus deformity, and other 15 patients' appearance were normal...
June 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29416163/fibulectomy-for-primary-proximal-fibular-bone-tumors-a-functional-and-clinical-outcome-in-46-patients
#10
Zile Singh Kundu, Milind Tanwar, Parveen Rana, Rajeev Sen
Background: Primary benign and malignant tumors of the proximal fibula are not very common. Upper fibula being an expendable bone; the majority of the primary bone tumors at this site are usually treated with en bloc proximal fibulectomy. There is scarce literature on functional results, difficulties faced during dissection when to preserve or sacrifice common peroneal nerve and importance of lateral collateral ligament repair after proximal fibulectomy. The present study attempts at assessing these variables...
January 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29408411/teriparatide-human-pth1-34-compensates-for-impaired-fracture-healing-in-cox-2-deficient-mice
#11
Kiminori Yukata, Chao Xie, Tian-Fang Li, Matthew L Brown, Tsukasa Kanchiku, Xinping Zhang, Hani A Awad, Edward M Schwarz, Christopher A Beck, Jennifer H Jonason, Regis J O'Keefe
Genetic ablation of cyclooxygenase-2 (COX-2) in mice is known to impair fracture healing. To determine if teriparatide (human PTH1-34) can promote healing of Cox-2-deficient fractures, we performed detailed in vivo analyses using a murine stabilized tibia fracture model. Periosteal progenitor cell proliferation as well as bony callus formation was markedly reduced in Cox-2-/- mice at day 10 post-fracture. Remarkably, intermittent PTH1-34 administration increased proliferation of periosteal progenitor cells, restored callus formation on day 7, and enhanced bone formation on days 10, 14 and 21 in Cox-2-deficient mice...
February 2, 2018: Bone
https://www.readbyqxmd.com/read/29404660/peripheral-dxa-measurement-around-ankle-joint-to-diagnose-osteoporosis-as-assessed-by-central-dxa-measurement
#12
Ki Hyuk Sung, Young Choi, Gyeong Hee Cho, Chin Youb Chung, Moon Seok Park, Kyoung Min Lee
OBJECTIVE: This study evaluated the correlation between central and peripheral bone mineral density (BMD) of the ankle joint, using dual-energy X-ray absorptiometry (DXA). We also investigated whether peripheral ankle BMD could be used to identify individuals who were diagnosed with osteoporosis, using central DXA. METHODS: We recruited 134 volunteers aged 20-90 years who agreed to participate in this study. Central BMD of the lumbar spine and left femur, and peripheral BMD of the medial malleolus, distal tibia, lateral malleolus, and talus were measured with DXA...
February 5, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29402427/novel-implant-for-peri-prosthetic-proximal-tibia-fractures
#13
Ton Tran, Bernard K Chen, Xinhua Wu, Chung Lun Pun
BACKGROUND: Repair of peri-prosthetic proximal tibia fractures is very challenging in patients with a total knee replacement or arthroplasty. The tibial component of the knee implant severely restricts the fixation points of the tibial implant to repair peri-prosthetic fractures. A novel implant has been designed with an extended flange over the anterior of tibial condyle to provide additional points of fixation, overcoming limitations of existing generic locking plates used for proximal tibia fractures...
February 2, 2018: Injury
https://www.readbyqxmd.com/read/29396777/bone-strength-in-growing-rats-treated-with-fluoride-a-multi-dose-histomorphometric-biomechanical-and-densitometric-study
#14
Brenda Lorena Fina, Maela Lupo, Eugenia Rocío Da Ros, Mercedes Lombarte, Alfredo Rigalli
Bone deformation and fragility are common signs of skeletal fluorosis. Disorganisation of bone tissue and presence of inflammatory foci were observed after fluoride (F-) administration. Most information about F- effects on bone has been obtained in adult individuals. However, in fluorosis areas, children are a population very exposed to F- and prone to develop not only dental but also skeletal fluoroses. The aim of this work was to evaluate the bone parameters responsible for the effect of different doses of F- on fracture load of the trabecular and cortical bones using multivariate analysis in growing rats...
February 2, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29396757/epidemiology-of-open-tibia-fractures-in-a-population-based-database-update-on-current-risk-factors-and-clinical-implications
#15
Christian David Weber, Frank Hildebrand, Philipp Kobbe, Rolf Lefering, Richard M Sellei, Hans-Christoph Pape
BACKGROUND: Open tibia fractures usually occur in high-energy mechanisms and are commonly associated with multiple traumas. The purposes of this study were to define the epidemiology of open tibia fractures in severely injured patients and to evaluate risk factors for major complications. METHODS: A cohort from a nationwide population-based prospective database was analyzed (TraumaRegister DGU®). Inclusion criteria were: (1) open or closed tibia fracture, (2) Injury Severity Score (ISS) ≥ 16 points, (3) age ≥ 16 years, and (4) survival until primary admission...
February 2, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29394444/new-reference-pmhs-tests-to-assess-whole-body-pedestrian-impact-using-a-simplified-generic-vehicle-front-end
#16
Eric Song, Philippe Petit, Xavier Trosseille, Jerome Uriot, Pascal Potier, Denis Dubois, Richard Douard
This study aims to provide a set of reference post-mortem human subject tests which can be used, with easily reproducible test conditions, for developing and/or validating pedestrian dummies and computational human body models against a road vehicle. An adjustable generic buck was first developed to represent vehicle front-ends. It was composed of four components: two steel cylindrical tubes screwed on rigid supports in V-form represent the bumper and spoiler respectively, a quarter of a steel cylindrical tube represents the bonnet leading edge, and a steel plate represents the bonnet...
November 2017: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/29394438/human-foot-ankle-injuries-and-associated-risk-curves-from-under-body-blast-loading-conditions
#17
Sajal Chirvi, Frank Pintar, Narayan Yoganandan, Anjishnu Banerjee, Mike Schlick, William Curry, Liming Voo
Under body blast (UBB) loading to military transport vehicles is known to cause foot-ankle fractures to occupants due to energy transfer from the vehicle floor to the feet of the soldier. The soldier posture, the proximity of the event with respect to the soldier, the personal protective equipment (PPE) and age/sex of the soldier are some variables that can influence injury severity and injury patterns. Recently conducted experiments to simulate the loading environment to the human foot/ankle in UBB events (~5ms rise time) with variables such as posture, age and PPE were used for the current study...
November 2017: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/29394245/simulation-enabled-search-for-explanatory-mechanisms-of-the-fracture-healing-process
#18
Ryan C Kennedy, Meir Marmor, Ralph Marcucio, C Anthony Hunt
A significant portion of bone fractures fail to heal properly, increasing healthcare costs. Advances in fracture management have slowed because translation barriers have limited generation of mechanism-based explanations for the healing process. When uncertainties are numerous, analogical modeling can be an effective strategy for developing plausible explanations of complex phenomena. We demonstrate the feasibility of engineering analogical models in software to facilitate discovery of biomimetic explanations for how fracture healing may progress...
February 2, 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29393051/the-contribution-of-spect-ct-in-the-diagnosis-of-stress-fracture-of-the-proximal-tibia
#19
Berna Okudan, Nazım Coşkun, Pelin Arıcan
Stress fractures are injuries most commonly seen in the lower limbs and are usually caused by repetitive stress. While the distal and middle third of the tibia is the most frequent site for stress fractures (almost 50%), stress fractures of the proximal tibia is relatively rare and could be confused with other types of tibial fractures, thus altering management plans for the clinician. Early diagnosis of stress fractures is also important to avoid complications. Imaging plays an important role in the diagnosis of stress fractures, especially bone scan...
February 1, 2018: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/29392383/intramedullary-nailing-in-opening-wedge-high-tibial-osteotomy-in-vitro-test-for-validation-of-a-method-of-fixation
#20
Rene Burchard, Denise Katerla, Marina Hammer, Anke Pahlkötter, Christian Soost, Gerhard Dietrich, Arne Ohrndorf, Wolfgang Richter, Markus Lengsfeld, Hans-Jürgen Christ, Jan Adriaan Graw, Claus-Peter Fritzen
PURPOSE: Opening wedge high tibial osteotomy (HTO) as a treatment in unicompartimental osteoarthritis of the knee can significantly relieve pain and prevent or at least delay an early joint replacement. The fixation of the osteotomy has undergone development and refinements during the last years. The angle-stable plate fixator is currently one of the most commonly used plates in HTOs. The angular stable fixation between screws and the plate offers a high primary stability to retain the correction with early weight-bearing protocols...
February 1, 2018: International Orthopaedics
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