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Skin blood flow

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https://www.readbyqxmd.com/read/29792425/roasted-barley-extract-mugi-cha-containing-cyclo-d-phe-l-pro-prevents-lowering-of-cutaneous-blood-flow-and-skin-temperature-under-air-conditioning-a-randomized-double-blind-placebo-controlled-crossover-study
#1
Hiroshi Ashigai, Mai Mizutani, Yoshimasa Taniguchi, Yasuko Matsukura, Keiko Nakashima, Emiko Ikeshima, Hiroaki Yajima
Roasted barley extract (RBE), also known as mugi-cha, is a well-known healthy non-caffeinated beverage and its health functionality has been widely reported. Our previous clinical study showed that RBE affects cutaneous blood flow and skin temperature after cold water immersion, and that cyclo (D-Phe-L-Pro) is responsible for its effect. In this study, we investigated whether cyclo (D-Phe-L-Pro)-containing RBE prevents the decrease in cutaneous blood flow and skin temperature in an excessively air-conditioned room...
May 24, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29790611/anesthesia-effects-on-the-low-frequency-blood-flow-oscillations-in-mouse-skin
#2
M E Astashev, D A Serov, A V Tankanag
BACKGROUND: When laboratory animals are used one needs to anesthetize them before recording. However, the influence of anesthesia on animal blood flow oscillations has not been studied. The effects of two ways of anesthesia, zoletil-xylazine, and zoletil-nitrous oxide mixtures, on mouse skin perfusion using laser Doppler flowmetry (LDF) technique were studied. METHODS: BALB/c mice were used. LDF probe was placed on the ventral surface of the left hind paw. Spectral analysis of LDF signals was performed with continuous adaptive wavelet transform to identify and describe peripheral blood flow oscillations in mouse skin...
May 23, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29786124/evaluation-of-the-relationship-between-flap-tension-and-tissue-perfusion-in-implant-based-breast-reconstruction-using-laser-assisted-indocyanine-green-angiography
#3
Chae-Eun Yang, Soon Won Chung, Dong Won Lee, Dae Hyun Lew, Seung Yong Song
BACKGROUND: For implant-based breast reconstruction, inadequate tissue perfusion may cause devastating complications. Tissue tension by inadequate implant volume may reduce tissue perfusion by stretching and collapsing the capillaries. The SPY system is used to perform intraoperative fluorescence angiography with indocyanine green to assess visually the blood flow and evaluate tissue perfusion. However, there is no report yet about how mastectomy flap perfusion changes with the expander-filling volume...
May 21, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29777308/theoretical-analysis-of-evaporative-cooling-of-classic-heat-stroke-patients
#4
Abdulaziz H Alzeer, E H Wissler
Heat stroke is a serious health concern globally, which is associated with high mortality. Newer treatments must be designed to improve outcomes. The aim of this study is to evaluate the effect of variations in ambient temperature and wind speed on the rate of cooling in a simulated heat stroke subject using the dynamic model of Wissler. We assume that a 60-year-old 70-kg female suffers classic heat stroke after walking fully exposed to the sun for 4 h while the ambient temperature is 40 °C, relative humidity is 20%, and wind speed is 2...
May 18, 2018: International Journal of Biometeorology
https://www.readbyqxmd.com/read/29771921/mosquito-saliva-alone-has-profound-effects-on-the-human-immune-system
#5
Megan B Vogt, Anismrita Lahon, Ravi P Arya, Alexander R Kneubehl, Jennifer L Spencer Clinton, Silke Paust, Rebecca Rico-Hesse
Mosquito saliva is a very complex concoction of >100 proteins, many of which have unknown functions. The effects of mosquito saliva proteins injected into our skin during blood feeding have been studied mainly in mouse models of injection or biting, with many of these systems producing results that may not be relevant to human disease. Here, we describe the numerous effects that mosquito bites have on human immune cells in mice engrafted with human hematopoietic stem cells. We used flow cytometry and multiplex cytokine bead array assays, with detailed statistical analyses, to detect small but significant variations in immune cell functions after 4 mosquitoes fed on humanized mice footpads...
May 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29770191/electrolytically-generated-hydrogen-warm-water-cleanses-the-keratin-plug-clogged-hair-pores-and-promotes-the-capillary-blood-streams-more-markedly-than-normal-warm-water-does
#6
Yoshiharu Tanaka, Yasukazu Saitoh, Nobuhiko Miwa
Biomedical properties of hydrogen water have been extensively investigated, but the effect of hydrogen on good healthy subjects remains unclear. This study was designed to explore the hygiene improvement by electrolytically generated hydrogen warm water (40°C) on capillary blood streams, skin moisture, and keratin plugs in skin pores in normal good healthy subjects with their informed consents. Fingertip-capillary blood stream was estimated after hand-immersing in hydrogen warm water by videography using a CCD-based microscope, and the blood flow levels increased to about 120% versus normal warm water, after 60 minutes of the hand-immersing termination...
January 2018: Medical Gas Research
https://www.readbyqxmd.com/read/29766294/influence-of-dietary-nitrate-supplementation-on-local-sweating-and-cutaneous-vascular-responses-during-exercise-in-a-hot-environment
#7
Tatsuro Amano, Dai Okushima, Brynmor C Breese, Stephen J Bailey, Shunsaku Koga, Narihiko Kondo
PURPOSE: We investigated the influence of inorganic nitrate ([Formula: see text]) supplementation on local sweating and cutaneous vascular responses during exercise in hot conditions. METHOD: Eight healthy, young subjects were assigned in a randomized, double-blind, crossover design to receive [Formula: see text]-rich beetroot (BR) juice (140 mL/day, containing ~ 8 mmol of [Formula: see text]) and [Formula: see text]-depleted placebo (PL) juice (140 mL/day, containing ~ 0...
May 15, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29761072/sezary-syndrome-manifesting-as-posttransplant-lymphoproliferative-disorder
#8
Thanh-Phuong Afiat, Xiaohui Zhang, Hailing Zhang, Ernesto Ayala, Ling Zhang, Lubomir Sokol
Posttransplant lymphoproliferative disorders (PTLDs) of T-cell orgin are rare biologically heterogeneous diseases of mature lymphoid cells manifesting in immunosuppressed patients. Only a few cases of mycosis fungoides diagnosed post allogeneic hematopoietic cell transplant (alloHSCT) have been described so far. We present a patient with myelodysplastic syndrome (MDS) post matched unrelated donor alloHSCT who was on long-term immunosuppressive therapy due to graft versus host disease. Three years after an alloHSCT, she developed generalized erythroderma and peripheral blood lymphocytosis...
2018: Leukemia Research Reports
https://www.readbyqxmd.com/read/29757755/sinking-skin-flap-syndrome-after-decompressive-craniectomy-a-case-report
#9
Nicholas Fawley, Chiedozie Udeh
Sinking skin flap syndrome is a rare complication of decompressive craniectomy characterized by a sunken skin flap, neurological deterioration, and paradoxical herniation of the brain. An absent cranium allows for external compression via atmospheric pressure, causing alterations in cerebral blood flow, cerebral spinal fluid flow, and glucose metabolism, which ultimately leads to cortical dysfunction. This case report describes a patient with relatively early onset of variable neurological symptoms and imaging correlation, leading to a diagnosis and definitive therapeutic intervention with cranioplasty...
May 11, 2018: A&A practice
https://www.readbyqxmd.com/read/29757424/continuous-monitoring-of-kidney-transplant-perfusion-with-near-infrared-spectroscopy
#10
Georgia Malakasioti, Stephen D Marks, Tom Watson, Fariba Williams, Mariesa Taylor-Allkins, Nizam Mamode, Justin Morgan, Wesley N Hayes
Background: Current reliance on clinical, laboratory and Doppler ultrasound (DUS) parameters for monitoring kidney transplant perfusion in the immediate post-operative period in children risks late recognition of allograft hypoperfusion and vascular complications. Near-infrared spectroscopy (NIRS) is a real-time, non-invasive technique for monitoring tissue oxygenation percutaneously. NIRS monitoring of kidney transplant perfusion has not previously been validated to the gold standard of DUS...
May 11, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29753516/is-endothelial-microvascular-function-equally-impaired-among-patients-with-chronic-chagas-and-ischemic-cardiomyopathy
#11
Juliana Pereira Borges, Fernanda de Souza Nogueira Sardinha Mendes, Gabriella de Oliveira Lopes, Andréa Silvestre de Sousa, Mauro Felippe Felix Mediano, Eduardo Tibiriçá
BACKGROUND: Chronic Chagas cardiomyopathy (CCC) and cardiomyopathies due to other etiologies involve differences in pathophysiological pathways that are still unclear. Systemic microvascular abnormalities are associated with the pathogenesis of ischemic heart disease. However, systemic microvascular endothelial function in CCC remains to be elucidated. Thus, we compared the microvascular endothelial function of patients presenting with CCC to those with ischemic cardiomyopathy disease...
May 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29752146/a-novel-topical-nonsteroidal-trpv1-antagonist-pac-14028-cream-improves-skin-barrier-function-and-exerts-anti-inflammatory-action-through-modulating-epidermal-differentiation-markers-and-suppressing-th2-cytokines-in-atopic-dermatitis
#12
Ji-Hae Lee, Chang Soon Choi, Il-Hong Bae, Jin Kyu Choi, Young-Ho Park, Miyoung Park
BACKGROUND: Although it is established that epidermal barrier disturbance and immune dysfunction resulting in IgE sensitization are critical factors in the development of cutaneous inflammation, the pathogenesis and targeted therapy of atopic dermatitis (AD)-specific pathways have still been unknown. OBJECTIVE: Taking into account the fact that Th2 cytokines in AD have both unique and overlapping functions including increased epidermal thickening, inflammation, and decreased expressing of the barrier proteins keratinocyte differentiation, we sought to clarify our hypothesis that TRPV1 antagonist plays a critical role in skin barrier function and can be a therapeutic target for AD...
April 30, 2018: Journal of Dermatological Science
https://www.readbyqxmd.com/read/29749910/a-novel-low-cost-reusable-high-fidelity-neurosurgical-training-simulator-for-cerebrovascular-bypass-surgery
#13
Ulas Cikla, Balkan Sahin, Sahin Hanalioglu, Azam S Ahmed, David Niemann, Mustafa K Baskaya
OBJECTIVE Cerebrovascular bypass surgery is a challenging yet important neurosurgical procedure that is performed to restore circulation in the treatment of carotid occlusive diseases, giant/complex aneurysms, and skull base tumors. It requires advanced microsurgical skills and dedicated training in microsurgical techniques. Most available training tools, however, either lack the realism of the actual bypass surgery (e.g., artificial vessel, chicken wing models) or require special facilities and regulations (e...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29748072/nicorandil-reduces-burn-wound-progression-by-enhancing-skin-blood-flow
#14
Jaehoon Choi, Ryeolwoo Kim, Junhyung Kim, Woonhyeok Jeong, Sang Woo Park, Hyoun Wook Lee, Ho Yun Chung
We assessed whether nicorandil, an adenosine triphosphate-sensitive K + channel opener, reduces burn wound progression in a rat comb burn model. A total of 24 rats were used. Following thermal injury, one dose of nicorandil (10 or 30 mg/kg) was administered intragastrically twice daily for 3 days. At days 1 and 3 after injury, skin was harvested for histopathological examination and protein isolation. Rats treated with the 10-mg/kg and 30-mg/kg doses of nicorandil exhibited significantly increased tissue survival in the zone of stasis at days 1 and 3 after injury...
April 12, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29745802/cardiovascular-responses-to-exercise-when-increasing-skin-temperature-with-narrowing-of-the-core-to-skin-temperature-gradient
#15
Ting-Heng Chou, Jakob R Allen, Dongwoo Hahn, Brian K Leary, Edward F Coyle
The decline in stroke volume (SV) during exercise in the heat has been attributed to either an increase in cutaneous blood flow (CBF) that reduces venous return or an increase in heart rate (HR) that reduces cardiac filling time. However, the evidence supporting each mechanism arises under experimental conditions with different skin temperatures (Tsk ) (e.g.; {greater than or equal to}38{degree sign}C vs. {less than or equal to}36{degree sign}C respectively). We systematically studied cardiovascular responses to progressively increased Tsk (32{degree sign}C to 39{degree sign}C) with narrowing of the core-to-skin gradient during moderate intensity exercise...
May 10, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29744385/changes-in-blood-flow-at-the-mandibular-angle-and-horner-syndrome-in-a-rat-model-of-superior-cervical-ganglion-block
#16
Kazutoshi Kubota, Katsuhisa Sunada
Background: A stellate ganglion block (SGB) causes increased blood flow in the maxillofacial region, exhibiting the potential for regenerative effects in damaged tissue. The focus of this study was to understand the efficacy of SGB for regenerative effects against nerve damage. A rat model of the superior cervical ganglion block (SCGB) was created instead of SGB, and facial blood flow, as well as sympathetic nervous system function, were measured. Methods: A vertical incision was made on the left side of the neck of a Wistar rat, and a 5-mm resection of the superior cervical ganglion was performed at the back of the bifurcation of the internal and external branches of the left common carotid artery...
April 2018: Journal of Dental Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29743767/pressure-ulcer-and-nutrition
#17
REVIEW
Seied Hadi Saghaleini, Kasra Dehghan, Kamran Shadvar, Sarvin Sanaie, Ata Mahmoodpoor, Zohreh Ostadi
Pressure ulcers can diminish global life quality, contribute to rapid mortality in some patients and pose a significant cost to health-care organizations. Accordingly, their prevention and management are highly important. Nutritional deprivation and insufficient dietary intake are the key risk factors for the development of pressure ulcers and impaired wound healing. Unplanned weight loss is a major risk factor for malnutrition and pressure ulcer development. Suboptimal nutrition interferes with the function of the immune system, collagen synthesis, and tensile strength...
April 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29740880/fundamental-supply-of-skin-blood-flow-in-the-chinese-han-population-measurements-by-a-full-field-laser-perfusion-imager
#18
W Fei, S Xu, J Ma, W Zhai, S Cheng, Y Chang, X Wang, J Gao, H Tang, S Yang, X Zhang
BACKGROUND: Skin blood flow is believed to link with many diseases, and shows a significant heterogeneity. There are several papers on basal cutaneous microcirculation perfusion in different races, while the data in Chinese is vacant. OBJECTIVE: The aim was to establish the database of absolute fundamental supply of skin blood flow in the Chinese Han population. METHODS: With a full-field laser perfusion imager (FLPI), the skin blood flow can be quantified...
May 8, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29725778/skin-microcirculatory-reactivity-assessed-using-a-thermal-challenge-is-decreased-in-patients-with-circulatory-shock-and-associated-with-outcome
#19
Diego Orbegozo, Wasineenart Mongkolpun, Gianni Stringari, Nikolaos Markou, Jacques Creteur, Jean-Louis Vincent, Daniel De Backer
BACKGROUND: Shock states are characterized by impaired tissue perfusion and microcirculatory alterations, which are directly related to outcome. Skin perfusion can be noninvasively evaluated using skin laser Doppler (SLD), which, when coupled with a local thermal challenge, may provide a measure of microcirculatory reactivity. We hypothesized that this microvascular reactivity would be impaired in patients with circulatory shock and would be a marker of severity. METHODS: We first evaluated skin blood flow (SBF) using SLD on the forearm and on the palm in 18 healthy volunteers to select the site with maximal response...
May 3, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29723883/adipose-derived-stem-cells-ameliorates-ischemia-reperfusion-injury-in-a-rat-skin-free-flap-model
#20
Alberto Ballestín, Javier G Casado, Elena Abellán, Francisco Javier Vela, Verónica Álvarez, Alejandra Usón, Rebeca Blázquez, Francisco M Sánchez-Margallo
BACKGROUND:  Ischemia-reperfusion (I/R) injury is inevitable during free tissue transfers. When the period of ischemia exceeds the tissue tolerance, it causes necrosis and flap failure. The aim of this study was to investigate the effects of adipose-derived stem cells (ASCs) embedded in a collagen type I scaffold on the survival of free skin flaps to counteract I/R injury. METHODS:  Left superficial caudal epigastric skin flaps (3 × 6 cm) were performed in 28 Wistar rats that were divided into four groups...
May 3, 2018: Journal of Reconstructive Microsurgery
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