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https://www.readbyqxmd.com/read/28324927/estimation-of-arterio-venous-access-blood-flow-in-hemodialysis-patients-using-video-image-processing-technique
#1
Fansan Zhu, Schantel Williams, Hannah Putnam, Israel Campos, Jie Ma, Camille Johnson, Franz Kappel, Peter Kotanko
Assessment of arterio-venous fistula (AVF) blood flow (ABF) is vital in hemodialysis (HD) patients. Currently, no non-invasive and contact-free technique is available to accurately measure ABF in routine clinical practice. In this study, we developed a novel approach using video image processing (VIP) to measure the change in optic flow in the skin. We the tested the hypothesis that the change in optical flow, expressed as the change in pixels between consecutive frames, is related to ABF. We recorded AVF videos in 40 HD patients using a digital camera and processed them by VIP technique...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28321638/wearing-graduated-compression-stockings-augments-cutaneous-vasodilation-in-heat-stressed-resting-humans
#2
Naoto Fujii, Toshiya Nikawa, Bun Tsuji, Narihiko Kondo, Glen P Kenny, Takeshi Nishiyasu
PURPOSE: We investigated whether graduated compression induced by stockings enhances cutaneous vasodilation in passively heated resting humans. METHODS: Nine habitually active young men were heated at rest using water-perfusable suits, resulting in a 1.0 °C increase in body core temperature. Heating was repeated twice on separate occasions while wearing either (1) stockings that cause graduated compression (pressures of 26.4 ± 5.3, 17.5 ± 4.4, and 6...
March 20, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28321017/a-non-invasive-technique-for-the-evaluation-of-peripheral-circulatory-functions-in-female-subjects-with-raynaud-s-phenomenon
#3
Seyed Mohammad Mirbod, Haruo Sugiura
Japanese women now account for 43 percent of the labor force. A number of them are involved in construction, agricultural and forestry jobs. The aim of this study was to establish a non-invasive technique for the evaluation of peripheral circulatory functions in women with Raynaud's phenomenon (RP); and introduce a specific method for the assessment of vascular disturbances in females exposed to hand-transmitted vibration. The subjects of this study were 10 women with primary RP, 7 women with progressive systemic sclerosis (PSS) secondary to RP, and 17 females who were included as the control group...
March 17, 2017: Industrial Health
https://www.readbyqxmd.com/read/28320323/changes-in-duration-of-action-of-rocuronium-following-decrease-in-hepatic-blood-flow-during-pneumoperitoneum-for-laparoscopic-gynaecological-surgery
#4
Yang Liu, Wen Cao, Yu Liu, Yun Wang, Ren Lang, Yun Yue, An-Shi Wu
BACKGROUND: A moderate insufflation pressure and deep neuromuscular blockade (NMB) have been recommended in laparoscopic surgery in consideration of the possible reduction in splanchnic perfusion due to the CO2-pneumoperitoneum. Since the liver is the major organ for rocuronium metabolism, the question of whether NMB of rocuronium would change with the variation of liver perfusion during pneumoperitoneum during laparoscopic surgery merits investigation. METHODS: In this prospective study, a total of sixty female patients scheduled for either selective laparoscopic gynaecological surgery (group laparoscopy) or laparotomy for gynaecological surgery (group control) were analyzed...
March 20, 2017: BMC Anesthesiology
https://www.readbyqxmd.com/read/28304107/the-percutaneous-toxicokinetics-of-sulphur-mustard-in-a-damaged-skin-porcine-model-and-the-evaluation-of-woundstat%C3%A2-as-a-topical-decontaminant
#5
Charlotte A Hall, Helen L Lydon, Christopher H Dalton, J Kevin Chipman, John S Graham, Robert P Chilcott
This study used a damaged skin, porcine model to evaluate the in vivo efficacy of WoundStat™ for decontamination of superficial (non-haemorrhaging), sulphur mustard-contaminated wounds. The dorsal skin of 12 female pigs was subjected to controlled physical damage and exposed to 10 μL (14) C-radiolabelled sulphur mustard ((14) C-SM). Animals were randomly assigned to either a control or a treatment group. In the latter, WoundStat™ was applied 30 s post exposure and left in situ for 1 h. Skin lesion progression and decontaminant efficacy were quantified over 6 h using a range of biophysical measurements...
March 17, 2017: Journal of Applied Toxicology: JAT
https://www.readbyqxmd.com/read/28295631/relationship-between-the-changes-in-blood-flow-and-volume-in-the-finger-during-a-braille-character-discrimination-task
#6
J Murata, S Murata, M Soma, H Nakae, Y Sato, H Kogo, N Umeki
PURPOSE: We hypothesized that skin blood flow (SBF) of fingers are modulated during concentrated finger perception and that the changes in SBF reflect fluctuations in finger volume (FV). The aim of this study, therefore, was examine the relationship between the changes in SBF and FV during Braille reading. METHODS: We measured SBF of the finger, cutaneous vascular conductance (CVC), FV, and arterial blood pressure during Braille reading performed under blind conditions in thirty healthy subjects...
March 14, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28293809/a-mesenteric-traction-syndrome-affects-near-infrared-spectroscopy-evaluated-cerebral-oxygenation-because-skin-blood-flow-increases
#7
Niels D Olesen, Henrik Sørensen, Rikard Ambrus, Lars B Svendsen, Anton Lund, Niels H Secher
During abdominal surgery manipulation of internal organs may induce a "mesenteric traction syndrome" (MTS) including a triad of flushing, hypotension, and tachycardia that lasts for about 30 min. We evaluated whether MTS affects near-infrared spectroscopy (NIRS) assessed frontal lobe oxygenation (ScO2) by an increase in forehead skin blood flow (SkBF). The study intended to include 10 patients who developed MTS during pancreaticoduodenectomy and 22 patients were enrolled (age 61 ± 8 years; mean ± SD)...
March 14, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28293753/cd16-positive-circulating-monocytes-and-fibrotic-manifestations-of-systemic-sclerosis
#8
Alain Lescoat, Valérie Lecureur, Mikael Roussel, Béatrice Ly Sunnaram, Alice Ballerie, Guillaume Coiffier, Stéphane Jouneau, Olivier Fardel, Thierry Fest, Patrick Jégo
The objective of this study is to assess the association of clinical manifestations of systemic sclerosis (SSc) with the absolute count of circulating blood monocyte subpopulations according to their membrane expression of CD16. Forty-eight consecutive patients fulfilling the 2013 ACR/EULAR classification criteria for SSc were included in this cross-sectional study. CD16+ monocyte absolute count was defined by flow cytometry and confronted to the clinical characteristics of SSc patients. Twenty-three healthy donors (HD) were randomly selected for comparison...
March 14, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28293502/microvascular-fragment-transplantation-improves-rat-dorsal-skin-flap-survival
#9
Randolph Stone, Christopher R Rathbone
BACKGROUND: The development of flap necrosis distally remains a concern during microsurgical flap transfers because, at least in part, of decreased perfusion. Microvascular fragments (MVFs) are microvessels isolated from adipose tissue that are capable of improving tissue perfusion in a variety of tissue defects. The aim of this study was to determine whether the transplantation of MVFs in a dorsal rat skin flap model can improve flap survival. METHODS: A 10 × 3 cm flap was raised in a cranial to caudal fashion on the dorsal side of 16 Lewis rats, with the caudal side remaining intact...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28291474/the-development-of-a-probabilistic-dose-response-for-a-burn-injury-model
#10
Anthony Iyoho, Laurel Ng, Philemon Chan
OBJECTIVE: The objective was to augment a burn injury model, BURNSIM, with probabilistic dose-response risk curves. METHODS: To develop the dose-response, we drew on a considerable amount of historical porcine burn injury data collected by U.S. Army Aeromedical Research Laboratory in the 1970s. The experimental parameters of each usable data point served as inputs to BURNSIM to calculate the burn damage integral (i.e., the internal dose) for 4 severities (mild, intermediate, deep second- and third-degree burns)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28286048/effect-of-age-on-cutaneous-vasomotor-responses-during-local-skin-heating
#11
Gary J Hodges, Matthew M Mallette, Garry A Tew, John M Saxton, James Moss, Alan D Ruddock, Markos Klonizakis
This study examined the effect of ageing on the low-frequency oscillations (vasomotion) of skin blood flow in response to local heating (LH). Skin blood flow was assessed by laser-Doppler flowmetry on the forearm at rest (33°C) and in response to LH of the skin to both 42°C and 44°C in 14 young (24±1years) and 14 older (64±1years) participants. Vasomotion was analyzed using a wavelet transform to investigate power of the frequency intervals associated with endothelial, neural, myogenic, respiratory, and cardiac activities of the laser-Doppler signal...
March 9, 2017: Microvascular Research
https://www.readbyqxmd.com/read/28285619/the-anatomical-study-of-the-major-signal-points-of-the-court-type-thai-traditional-massage-on-legs-and-their-effects-on-blood-flow-and-skin-temperature
#12
Yadaridee Viravud, Angkana Apichartvorakit, Pramook Mutirangura, Vasana Plakornkul, Jantima Roongruangchai, Manmas Vannabhum, Tawee Laohapand, Pravit Akarasereenont
OBJECTIVE: This study aims to investigate the relationship between major signal points (MaSPs) of the lower extremities used in court-type Thai traditional massage (CTTM) and the corresponding underlying anatomical structures, as well as to determine the short-term changes in blood flow and skin temperature of volunteers experiencing CTTM. METHODS: MaSPs were identified and marked on cadavers before acrylic color was injected. The underlying structures marked with acrylic colors were observed and the anatomical structures were determined...
March 2017: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28283718/measuring-transdermal-glucose-levels-in-neonates-by-passive-diffusion-an-in-vitro-porcine-skin-model
#13
Cristina Tiangco, Abhay Andar, Juliana Quarterman, Xudong Ge, Fortunato Sevilla, Govind Rao, Audra Stinchcomb, Annette Bunge, Leah Tolosa
Current glucose monitoring techniques for neonates rely heavily on blood glucose monitors which require intermittent blood collection through skin-penetrating pricks on the heel or fingers. This procedure is painful and often not clinically conducive, which presents a need for a noninvasive method for monitoring glucose in neonates. Our motivation for this study was to develop an in vitro method for measuring passive diffusion of glucose in premature neonatal skin using a porcine skin model. Such a model will allow us to initially test new devices for noninvasive glucose monitoring without having to do in vivo testing of newborns...
March 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28280382/retention-of-finger-blood-flow-against-postural-change-as-an-indicator-of-successful-sympathetic-block-in-the-upper-limb
#14
Toshihiko Nakatani, Tatsuya Hashimoto, Ichiro Sutou, Yoji Saito
BACKGROUND: Sympathetic block in the upper limb has diagnostic, therapeutic and prognostic utility for disorders in the upper extremity that are associated with sympathetic disturbances. Increased skin temperature and decreased sweating are used to identify the adequacy of sympathetic block in the upper limb after stellate ganglion block (SGB). Baroreflexes elicited by postural change induce a reduction in peripheral blood flow by causing sympathetic vasoconstriction. We hypothesized that sympathetic block in the upper limb reduces the decrease in finger blood flow caused by baroreflexes stimulated by postural change from the supine to long sitting position...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28279918/near-infrared-light-activation-of-quenched-liposomal-ce6-for-synergistic-cancer-phototherapy-with-effective-skin-protection
#15
Liangzhu Feng, Danlei Tao, Ziliang Dong, Qian Chen, Yu Chao, Zhuang Liu, Meiwan Chen
Current photodynamic therapy (PDT) is suffering from limited efficacy towards hypoxia tumors and severe post-treatment photo-toxicity such as light-induced skin damages. To make PDT more effective in cancer treatment while being patient-comfortable, herein, a hexylamine conjugated chlorin e6 (hCe6) as the photosensitizer together with a lipophilic near-infrared (NIR) dye 1,1'-dioctadecyl-3,3,3',3'-tetramethylindotricarbocyanine iodide (DiR) are co-encapsulated into polyethylene glycol (PEG) shelled liposomes...
November 21, 2016: Biomaterials
https://www.readbyqxmd.com/read/28275123/body-monitoring-with-photonic-textiles-a-reflective-heartbeat-sensor-based-on-polymer-optical-fibres
#16
Brit M Quandt, Fabian Braun, Damien Ferrario, René M Rossi, Anke Scheel-Sailer, Martin Wolf, Gian-Luca Bona, Rudolf Hufenus, Lukas J Scherer, Luciano F Boesel
Knowledge of an individual's skin condition is important for pressure ulcer prevention. Detecting early changes in skin through perfusion, oxygen saturation values, and pressure on tissue and subsequent therapeutic intervention could increase patients' quality of life drastically. However, most existing sensing options create additional risk of ulcer development due to further pressure on and chafing of the skin. Here, as a first component, we present a flexible, photonic textile-based sensor for the continuous monitoring of the heartbeat and blood flow...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28275061/impaired-sweating-responses-to-a-passive-whole-body-heat-stress-in-individuals-with-multiple-sclerosis
#17
Dustin R Allen, Mu Huang, Iqra M Parupia, Ariana R Dubelko, Elliot M Frohman, Scott L Davis
Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system (CNS), disrupting autonomic function. The aim of this study was to test the hypothesis that individuals with MS have blunted control of thermoregulatory reflex increases in sweat rate (SR) and cutaneous vasodilation compared to controls during a passive whole-body heat stress (WBH). Eighteen individuals with relapsing-remitting MS and 18 healthy controls (CON) participated in the study. Core temperature (Tcore), skin temperature, heart rate, arterial blood pressure (10 min intervals), skin blood flow (laser-Doppler flux: LDF), and SR were continuously measured during normothermic baseline (34 °C water perfusing a tube-lined suit) and WBH (increased Tcore 0...
March 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28272145/improved-survival-of-full-thickness-skin-graft-with-low-molecular-weight-heparin-protamine-micro-nanoparticles-including-platelet-rich-plasma
#18
Yuki Takabayashi, Masayuki Ishihara, Masahiro Kuwabara, Makoto Takikawa, Shingo Nakamura, Hidemi Hattori, Tomoharu Kiyosawa
BACKGROUND: Activated platelet-rich plasma secrets many growth factors (GFs), and low-molecular weight heparin-protamine micro/nanoparticles (LMWH-P M/NPs) significantly interact with, enhance, and stabilize the secreted GFs. OBJECTIVE: The purpose of this study was to evaluate the effects of LMWH-P M/NPs and GFs (from platelet-rich plasma) on full-thickness skin graft (FTSG). METHODS: A total of 96 inbred male rats were anesthetized and 4-cm full-thickness skin wound were created on dorsal skin of rats...
March 8, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28271003/optical-coherence-tomography-based-angiography-invited
#19
REVIEW
Chieh-Li Chen, Ruikang K Wang
Optical coherence tomography (OCT)-based angiography (OCTA) provides in vivo, three-dimensional vascular information by the use of flowing red blood cells as intrinsic contrast agents, enabling the visualization of functional vessel networks within microcirculatory tissue beds non-invasively, without a need of dye injection. Because of these attributes, OCTA has been rapidly translated to clinical ophthalmology within a short period of time in the development. Various OCTA algorithms have been developed to detect the functional micro-vasculatures in vivo by utilizing different components of OCT signals, including phase-signal-based OCTA, intensity-signal-based OCTA and complex-signal-based OCTA...
February 1, 2017: Biomedical Optics Express
https://www.readbyqxmd.com/read/28268584/the-use-of-a-thermal-camera-and-eulerian-enhancement-in-the-examination-of-pedal-pulse-and-microvascular-health
#20
Stephanie L Bennett, Rafik A Goubran, Brendan Bennett, Rebecca A Bennett, Frank Knoefel
Early detection of impaired blood flow and microvascular functioning is important to prevent ulceration in diabetic patients. This paper aims to first determine if thermal video in conjunction with Eulerian Video Magnification (EVM) can be used to find the pedal pulse rate, and reveal patterns indicative of the foot's microvascular health. Thermal video was captured of a healthy adult's foot while a Doppler ultrasound captured pedal pulse. Another thermal video was captured of a patient's heels. These videos were subjected to EVM, areas of interest were defined and the mean intensity signal was calculated temporally, within each defined area...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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