Read by QxMD icon Read

Pregnancy simulation

Katherine A Guthrie, Hilary S Gammill, Mads Kamper-Jørgensen, Anne Tjønneland, Vijayakrishna K Gadi, J Lee Nelson, Wendy Leisenring
Natural acquisition of small amounts of foreign cells or DNA, referred to as microchimerism, occurs primarily through maternal-fetal exchange during pregnancy. Microchimerism can persist long-term and has been associated with both beneficial and adverse human health outcomes. Quantitative microchimerism data present challenges for statistical analysis, including a skewed distribution, excess zero values, and occasional large values. Methods for comparing microchimerism levels across groups while controlling for covariates are not well established...
October 21, 2016: American Journal of Epidemiology
Marie Hauguel-Moreau, Julien Adjedj
No abstract text is available yet for this article.
October 25, 2016: Journal of the American College of Cardiology
Courtney Stanley Sundin, Lauren Bradham Mazac
Amniotic fluid embolism (AFE) is a rare but serious and potentially deadly complication of pregnancy that is unpreventable and unpredictable. Most AFE events occur during labor; however, approximately one third happen during the immediate postpartum period. Presentation is abrupt and thought to be an abnormal response to fetal materials entering maternal circulation through the placental insertion site. Care providers must recognize the signs and symptoms of AFE and react quickly in effort to treat potential complications...
October 13, 2016: MCN. the American Journal of Maternal Child Nursing
Tiziana Frusca, Maria-Teresa Gervasi, Davide Paolini, Matteo Dionisi, Francesca Ferre, Irene Cetin
INTRODUCTION: Preeclampsia (PE) is a pregnancy disease which represents a leading cause of maternal and perinatal mortality and morbidity. Accurate prediction of PE risk could provide an increase in health benefits and better patient management. OBJECTIVE: To estimate the economic impact of introducing Elecsys sFlt-1/PlGF ratio test, in addition to standard practice, for the prediction of PE in women with suspected preeclampsia in the Italian NHS. METHODS: A decision tree model has been developed to simulate the progression of a cohort of pregnant women from the first presentation of clinical suspicion of PE in the 2nd and 3rd trimester until delivery...
October 13, 2016: Journal of Maternal-fetal & Neonatal Medicine
A F Fransen, J van de Ven, E Schuit, Aac van Tetering, B W Mol, S G Oei
OBJECTIVE: To investigate whether simulation-based obstetric team training in a simulation centre improves patient outcome. DESIGN: Multicentre, open, cluster randomised controlled trial. SETTING: Obstetric units in the Netherlands. POPULATION: Women with a singleton pregnancy beyond 24 weeks of gestation. METHODS: Random allocation of obstetric units to a 1-day, multi-professional, simulation-based team training focusing on crew resource management (CRM) in a simulation centre or to no such team training...
October 10, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
B O'Leary, A Khalid, M Higgins
Vaginal bleeding is a common event in early pregnancy, with 20-40% of pregnancies affected. Prompt diagnosis and management of bleeding is important, both to reduce morbidity and to avoid excessive emotional distress. This was a prospective study of an educational programme aimed at Obstetrics and Gynaecology BST trainees in the National Maternity Hospital, Dublin. The educational programme consisted of didactic lectures, and simulation and practical sessions. A questionnaire reviewing early pregnancy complications was used to assess participant knowledge...
2016: Irish Medical Journal
Xin Wang, Falk Poenisch, Narayan Sahoo, Ronald X Zhu, MingFwu Lii, Michael T Gillin, Jing Li, David Grosshans
This is a real case study to minimize the neutron dose equivalent (H) to a fetus using spot scanning proton beams with favorable beam energies and angles. Minimum neutron dose exposure to the fetus was achieved with iterative planning under the guidance of neutron H measurement. Two highly conformal treatment plans, each with three spot scanning beams, were planned to treat a 25-year-old pregnant female with aggressive recurrent chordoma of the base of skull who elected not to proceed with termination. Each plan was scheduled for delivery every other day for robust target coverage...
2016: Journal of Applied Clinical Medical Physics
Silke Fernandes, Elisa Sicuri, Diawara Halimatou, James Akazili, Kalifa Boiang, Daniel Chandramohan, Sheikh Coulibaly, Sory Ibrahim Diawara, Kassoum Kayentao, Feiko Ter Kuile, Pascal Magnussen, Harry Tagbor, John Williams, Arouna Woukeu, Matthew Cairns, Brian Greenwood, Kara Hanson
BACKGROUND: Emergence of high-grade sulfadoxine-pyrimethamine (SP) resistance in parts of Africa has led to growing concerns about the efficacy of intermittent preventive treatment of malaria during pregnancy (IPTp) with SP. The incremental cost-effectiveness of intermittent screening and treatment (ISTp) with artemether-lumefantrine (AL) as an alternative strategy to IPTp-SP was estimated followed by a simulation of the effects on cost-effectiveness of decreasing efficacy of IPTp-SP due to SP resistance...
2016: Malaria Journal
Carla Lupi, Melissa Ward-Peterson, Stefany Coxe, Suzanne Minor, Irmanie Eliacin, Vivian Obeso
OBJECTIVE: To further the validity of a tool to assess nondirective pregnancy options counseling skills. METHODS: Using a cross-sectional design, we explored four sources of construct validity evidence for an objective structured clinical examination for training and assessment of nondirective pregnancy options counseling: content, response process, internal structure, and relations to other variables. Content of the previously developed tool was enhanced through input from five family medicine educators...
October 2016: Obstetrics and Gynecology
Yuta Matsunaga, Ai Kawaguchi, Masanao Kobayashi, Shigetaka Suzuki, Shoichi Suzuki, Koichi Chida
The purposes of this study were (1) to compare the radiation doses for 320- and 80-row fetal-computed tomography (CT), estimated using thermoluminescent dosimeters (TLDs) and the ImPACT Calculator (hereinafter referred to as the "CT dosimetry software"), for a woman in her late pregnancy and her fetus and (2) to estimate the overlapped fetal radiation dose from a 320-row CT examination using two different estimation methods of the CT dosimetry software. The direct TLD data in the present study were obtained from a previous study...
September 19, 2016: Radiological Physics and Technology
Theodore A Slotkin, Ashley Stadler, Samantha Skavicus, Jennifer Card, Jonathan Ruff, Edward D Levin, Frederic J Seidler
Secondhand tobacco smoke exposure in pregnancy increases the risk of neurodevelopmental disorders. We evaluated in rats whether there is a critical period during which tobacco smoke extract (TSE) affects the development of acetylcholine and serotonin systems, prominent targets for adverse effects of nicotine and tobacco smoke. We simulated secondhand smoke exposure by administering TSE so as to produce nicotine concentrations one-tenth those in active smoking, with three distinct, ten-day windows: premating, early gestation or late gestation...
September 14, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
Martin J C van Gemert, Michael G Ross, Peter G J Nikkels, Jeroen P H M van den Wijngaard
BACKGROUND: Acardiac monochorionic twins lack cardiac function but grow by passive perfusion of the pump twin's deoxygenated arterial blood through placental arterioarterial (AA) and venovenous (VV) anastomoses and by hypoxia-mediated neovascularization. Pump twins therefore must continuously increase their cardiac output which may cause heart failure. Our aims were: to adapt our twin-twin transfusion syndrome model for acardiac twin pregnancies, to simulate pump and acardiac twin development, and to examine the model for early prognostic markers of pump twin survival...
September 15, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
B Li, D S Sahota, T T Lao, J Xu, S Q Hu, L Zhang, Q Y Liu, Q Sun, D Tang, R M Ma
OBJECTIVE: To assess the feasibility and performance of the first-trimester combined screening test for trisomy 21 in a resource-limited setting in mainland China. DESIGN: Prospective observational cohort study. SETTING: First Affiliated Hospital of Kunming Medical University, China. POPULATION: Ten thousand four hundred and forty-two pregnant women requesting first-trimester screening. METHODS: The combined screening test was performed from May 2012 to December 2014...
September 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Michalis Mazonakis, Antonis Tzedakis, John Damilakis
This study estimated the fetal dose and risks from radiotherapy for breast cancer with 6 MV X-rays. Breast irradiation was simulated with the MCNP code using two mathematical phantoms corresponding to patients in the early and middle periods of pregnancy. Monte Carlo simulations were performed to determine the appropriate fetal shielding. For a 50-Gy tumor dose, the unshielded fetal dose reached up to 133.1 mGy. Fetal protection with a lead shield of dimensions 30 × 30 × 5 cm(3) placed besides the treatment couch resulted in maximum doses of 22...
September 9, 2016: Radiation Protection Dosimetry
Johanie Lépine, Maria Esther Leiva Portocarrero, Agathe Delanoë, Hubert Robitaille, Isabelle Lévesque, François Rousseau, Brenda J Wilson, Anik M C Giguère, France Légaré
BACKGROUND: Health professionals are expected to engage pregnant women in shared decision making to help them make informed values-based decisions about prenatal screening. Patient decision aids (PtDAs) foster shared decision-making, but are rarely used in this context. Our objective was to identify factors that could influence health professionals to use a PtDA for decisions about prenatal screening for Down syndrome during a clinical pregnancy follow-up. METHODS: We planned to recruit a purposive sample of 45 health professionals (obstetrician-gynecologists, family physicians and midwives) involved in the care of pregnant women in three clinical sites (15 per site)...
2016: BMC Pregnancy and Childbirth
Krista L Lentine, Dorry L Segev
Communicating the current knowledge of medical outcomes after live kidney donation necessary to support donor candidates in well informed decision-making requires grounding in perspectives of comparison. Baseline risk (without donating), risk attributable to donation, and absolute risk (after donating) need to be considered. Severe perioperative complications and death are rare, but vary by demographic, clinical, and procedure factors. Innovative capture of "healthy" controls designed to simulate donor selection processes has identified higher risk of ESRD attributable to donation in two studies; importantly, however, the absolute 15-year ESRD incidence in donors remains very low (0...
September 2, 2016: Journal of the American Society of Nephrology: JASN
Vassilis Fragoulakis, Chris P Pescott, Jesper M J Smeenk, Evert J P van Santbrink, G Jur E Oosterhuis, Frank J M Broekmans, Nikos Maniadakis
BACKGROUND AND OBJECTIVE: Subfertility represents a multidimensional problem associated with significant distress and impaired social well-being. In the Netherlands, an estimated 50,000 couples visit their general practitioner and 30,000 couples seek medical specialist care for subfertility. We conducted an economic evaluation comparing recombinant human follicle-stimulating hormone (follitropin alfa, r-hFSH, Gonal-F(®)) with two classes of urinary gonadotrophins-highly purified human menopausal gonadotrophin (hp-HMG, Menopur(®)) and urinary follicle-stimulating hormone (uFSH, Fostimon(®))-for ovarian stimulation in women undergoing in vitro fertilization (IVF) treatment in the Netherlands...
August 31, 2016: Applied Health Economics and Health Policy
Penghong Guo, Daniel E Rivera, Danielle S Downs, Jennifer S Savage
Excessive gestational weight gain (i.e., weight gain during pregnancy) is a significant public health concern, and has been the recent focus of novel, control systems-based interventions. This paper develops a control-oriented dynamical systems model based on a first-principles energy balance model from the literature, which is evaluated against participant data from a study targeted to obese and overweight pregnant women. The results indicate significant under-reporting of energy intake among the participant population...
July 2016: Proceedings of the ... American Control Conference
Sally A Brinkman, Sarah E Johnson, James P Codde, Michael B Hart, Judith A Straton, Murthy N Mittinty, Sven R Silburn
BACKGROUND: Infant simulator-based programmes, which aim to prevent teenage pregnancy, are used in high-income as well as low-income and middle-income countries but, despite growing popularity, no published evidence exists of their long-term effect. The aim of this trial was to investigate the effect of such a programme, the Virtual Infant Parenting (VIP) programme, on pregnancy outcomes of birth and induced abortion in Australia. METHODS: In this school-based pragmatic cluster randomised controlled trial, eligible schools in Perth, Western Australia, were enrolled and randomised 1:1 to the intervention and control groups...
August 24, 2016: Lancet
C Gaillard, O Martin, P Blavy, N C Friggens, J Sehested, H N Phuong
The GARUNS model is a lifetime performance model taking into account the changing physiological priorities of an animal during its life and through repeated reproduction cycles. This dynamic and stochastic model has been previously used to predict the productive and reproductive performance of various genotypes of cows across feeding systems. In the present paper, we used this model to predict the lifetime productive and reproductive performance of Holstein cows for different lactation durations, with the aim of determining the lifetime scenario that optimizes cows' performance defined by lifetime efficiency (ratio of total milk energy yield to total energy intake) and pregnancy rate...
August 24, 2016: Journal of Dairy Science
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"