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https://www.readbyqxmd.com/read/27936474/-three-years-follow-up-study-after-refractive-small-incision-lenticule-extraction-smile-using-500%C3%A2-khz-femtosecond-laser-in-fast-mode
#1
A Messerschmidt-Roth, W Sekundo, A Lazaridis, S Schulze
Background: The aim of this clinical trial was to check the results of laser built-in settings 3 years after ReLEx SMILE for moderate and high myopia in unselected "real life" patients. Patients and Methods: 50 myopic eyes of 27 patients were called in for examination after 3 years. 25 of these eyes with a preoperative myopia under - 6D comprised the "moderate myopia subgroup". All surgeries were performed with the 500 kHz VisuMax® femtosecond laser (Carl Zeiss Meditec AG, Jena) in the "fast mode" setting...
December 9, 2016: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/27936422/social-network-types-among-older-korean-adults-associations-with-subjective-health
#2
Sung Yun Sohn, Won-Tak Joo, Woo Jung Kim, Se Joo Kim, Yoosik Youm, Hyeon Chang Kim, Yeong-Ran Park, Eun Lee
With population aging now a global phenomenon, the health of older adults is becoming an increasingly important issue. Because the Korean population is aging at an unprecedented rate, preparing for public health problems associated with old age is particularly salient in this country. As the physical and mental health of older adults is related to their social relationships, investigating the social networks of older adults and their relationship to health status is important for establishing public health policies...
December 1, 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27936357/does-alcohol-contribute-to-college-men-s-sexual-assault-perpetration-between-and-within-person-effects-over-five-semesters
#3
Maria Testa, Michael J Cleveland
OBJECTIVE: The current longitudinal study was designed to consider the time-varying effects of men's heavy episodic drinking (HED) and drinking setting attendance on college sexual assault perpetration. METHOD: Freshman men (N = 992) were recruited in their first semester and completed online measures at the end of their first five semesters. Using multilevel models, we examined whether men with higher frequency HED (or party or bar attendance) were more likely to perpetrate sexual assault (between-person, Level 2 effect) and whether sexual assault perpetration was more likely in semesters in which HED (or party or bar attendance) was higher than each individual's average (within-person, Level 1 effect)...
January 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/27936115/long-term-changes-in-refractive-error-and-clinical-evaluation-in-partially-accommodative-esotropia-after-surgery
#4
Shin Yeop Oh, Ju-Yeun Lee, Kyung-Ah Park, Sei Yeul Oh
We investigate the changes in refractive error and clinical evaluation in partially accommodative esotropia(PAET) after surgery. A total of 68 patients PAET who received at least 2 years of follow-up after surgery were enrolled in this study. We performed a retrospective study in patients who underwent unilateral or bilateral medial rectus recession for a non-accommodative component of PAET between January 2005 and March 2013. Patients were divided into groups according to the presence of dominancy (dominant, non-dominant, alternative eye), and presence of amblyopia (amblyopic, fellow, normal eye)...
2016: PloS One
https://www.readbyqxmd.com/read/27935770/from-breast-cancer-to-antimicrobial-combating-extremely-resistant-gram-negative-superbugs-using-novel-combinations-of-polymyxin-b-with-selective-estrogen-receptor-modulators
#5
Maytham H Hussein, Elena K Schneider, Alysha G Elliott, Meiling Han, Felisa Reyes-Ortega, Faye Morris, Mark A T Blastovich, Raad Jasim, Bart Currie, Mark Mayo, Mark Baker, Matthew A Cooper, Jian Li, Tony Velkov
Novel therapeutic approaches are urgently needed to combat nosocomial infections caused by extremely drug-resistant (XDR) "superbugs." This study aimed to investigate the synergistic antibacterial activity of polymyxin B in combination with selective estrogen receptor modulators (SERMs) against problematic Gram-negative pathogens. In vitro synergistic antibacterial activity of polymyxin B and the SERMs tamoxifen, raloxifene, and toremifene was assessed using the microdilution checkerboard and static time-kill assays against a panel of Gram-negative isolates...
December 9, 2016: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/27935220/nuclear-co-repressor-ncor-is-required-to-maintain-insulin-sensitivity-in-c2-c12-myotubes
#6
Abhijeet K Choudhary, Chinmoy S Dey
Nuclear co-repressor (NCoR) regulate peripheral insulin sensitivity, however its role in modulating insulin sensitivity in skeletal muscle remains elusive. Present study investigated protein expression and effect of NCoR on insulin sensitivity in murine skeletal muscle cell line C2 C12 . Myotubes as compared to myoblasts of C2 C12 cells was found to be more sensitive in response to insulin as increase in insulin stimulated phosphorylation of AKT at serine 473 residue (pAKT(S473) ) was significantly higher in myotubes...
December 9, 2016: Cell Biology International
https://www.readbyqxmd.com/read/27935212/hemophilia-liver-transplantation-observational-study-hots
#7
Margaret V Ragni, Abhinav Humar, Peter G Stock, Emily A Blumberg, Bijan Eghtesad, John J Fung, Valentina Stosor, Nicholas Nissen, Michael T Wong, Kenneth E Sherman, Donald M Stablein, Burc Barin
: Hepatitis C (HCV) infection is the leading cause of liver disease in hemophilia. In those with HIV/HCV co-infection, the rate of liver disease progression is greater than in HCV mono-infected individuals. Despite antiretroviral therapy which slows HCV liver disease progression, some require transplantation. Whether transplant outcomes are worse in hemophilic (H) than non-hemophilic (NH) candidates is unknown. In order to determine rates and predictors of pre- and post-transplant survival, we conducted a retrospective observational study utilizing United Network for Organ Sharing (UNOS) national transplant registry data, comparing HCV+ H and NH candidates...
December 9, 2016: Liver Transplantation
https://www.readbyqxmd.com/read/27935210/mechanistic-insight-on-the-oxidation-of-organic-phenylselenides-by-h%C3%A2-o%C3%A2
#8
Giovanni Ribaudo, Massimo Bellanda, Ileana Menegazzo, Lando Peter Wolters, Marco Bortoli, Gerardo Ferrer-Sueta, Giuseppe Zagotto, Laura Orian
The oxidation of organic phenylselenides by H₂O₂ is investigated in model compounds, i.e. n-butyl phenyl selenide (PhSe(n-Bu)), bis(phenylselanyl)methane (PhSeMeSePh), diphenyl diselenide (PhSeSePh) and 1,2-bis(phenylselanyl)ethane (PhSeEtSePh). Through a combined experimental (¹H and ⁷⁷Se NMR) and computational approach, we characterize the direct oxidation of monoselenide to selenoxide, the stepwise double oxidation of PhSeMeSePh leading to different diastereomeric diselenoxides, the complete oxidation of the diphenyldiselenide leading to selenium-selenium bond cleavage and subsequent formation of the phenylseleninic product...
December 9, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27935142/sharing-information-about-cancer-with-one-s-family-is-associated-with-improved-quality-of-life
#9
Carlo Lai, Beatrice Borrelli, Paola Ciurluini, Paola Aceto
OBJECTIVE: The aim of this study was to investigate the association between cancer patients' ability to share information about their illness with their social network and attachment style dimensions, alexithymia and quality of life. We hypothesised that ability to share information about one's cancer with family, friends and medical teams would be positively associated with quality of life and secure attachment and negatively associated with alexithymia. METHODS: Forty-five cancer patients were recruited from the Psycho-oncology unit of the San Camillo-Forlanini Hospital in Rome...
December 9, 2016: Psycho-oncology
https://www.readbyqxmd.com/read/27935097/streaming-potential-of-superhydrophobic-microchannels
#10
Hung Mok Park, Damoa Kim, Se Young Kim
For the purpose of gaining larger streaming potential, it has been suggested to employ superhydrophobic microchannels with a large velocity slip. There are two kinds of superhydrophobic surfaces, one having a smooth wall with a large Navier slip coefficient caused by the hydrophobicity of the wall material, and the other having a periodic array of no- shear slots of air pockets embedded in a nonslip wall. The electrokinetic flows over these two superhydrophobic surfaces are modelled using the Navier-Stokes equation and convection-diffusion equations of the ionic species...
December 9, 2016: Electrophoresis
https://www.readbyqxmd.com/read/27935048/height-related-scaling-of-phloem-anatomy-and-the-evolution-of-sieve-element-end-wall-types-in-woody-plants
#11
Johannes Liesche, Marcelo R Pace, Qiyu Xu, Yongqing Li, Shaolin Chen
In the sieve elements (SEs) of the phloem, carbohydrates are transported throughout the whole plant from their site of production to sites of consumption or storage. SE structure, especially of the pore-rich end walls, has a direct effect on translocation efficiency. Differences in pore size and other features were interpreted as an evolutionary trend towards reduced hydraulic resistance. However, this has never been confirmed. Anatomical data of 447 species of woody angiosperms and gymnosperms were used for a phylogenetic analysis of end wall types, calculation of hydraulic resistance and correlation analysis with morphological and physiological variables...
December 9, 2016: New Phytologist
https://www.readbyqxmd.com/read/27934991/a-homogeneous-atomic-layer-mos2-1-x-se2x-alloy-prepared-by-low-pressure-chemical-vapor-deposition-and-its-properties
#12
Sima Umrao, Jaeho Jeon, Su Min Jeon, Young Jin Choi, Sungjoo Lee
We report the growth of large-area monolayer MoS2(1-x)Se2x alloys with controlled morphologies using a low-pressure chemical vapor deposition (CVD) method. MoS2(1-x)Se2x alloys with different morphologies, created using the same growth time, have been observed by controlling the gaseous MoO3 precursor on substrates placed in regions with different temperatures. TEM observations clearly reveal that the as-synthesized monolayer MoS2(1-x)Se2x alloy is crystalline, with a hexagonal structure. XPS, Raman mapping, and EDS mapping clearly show the homogeneous substitution of ∼2 atomic weight % Se through the whole crystal...
December 9, 2016: Nanoscale
https://www.readbyqxmd.com/read/27934653/leucine-and-mammalian-target-of-rapamycin-dependent-activation-of-muscle-protein-synthesis-in-aging
#13
REVIEW
Jean-Pascal De Bandt
The preservation or restoration of muscle mass is of prime importance for healthy aging. However, aging has been repeatedly shown to be associated with resistance of muscle to the anabolic effects of feeding. Leucine supplementation has been proposed as a possible strategy because of its regulatory role on protein homeostasis. Indeed, it acts independently of growth factors and leads to enhanced cap-dependent mRNA translation initiation and increased protein synthesis. Leucine acts as a signaling molecule directly at the muscle level via the activation of mammalian/mechanistic target of rapamycin complex 1 (mTORC1)...
December 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27934158/soft-x-ray-spectroscopy-of-a-complex-heterojunction-in-high-efficiency-thin-film-photovoltaics-intermixing-and-zn-speciation-at-the-zn-o-s-cu-in-ga-se2-interface
#14
Michelle Mezher, Rebekah Garris, Lorelle M Mansfield, Monika Blum, Dirk Hauschild, Kimberly Horsley, Douglas A Duncan, Wanli Yang, Marcus Bär, Lothar Weinhardt, Kannan Ramanathan, Clemens Heske
The chemical structure of the Zn(O,S)/Cu(In,Ga)Se2 interface in high-efficiency photovoltaic devices is investigated using X-ray photoelectron and Auger electron spectroscopy, as well as soft X-ray emission spectroscopy. We find that the Ga/(Ga+In) ratio at the absorber surface does not change with the formation of the Zn(O,S)/Cu(In,Ga)Se2 interface. Furthermore, we find evidence for Zn in multiple bonding environments, including ZnS, ZnO, Zn(OH)2, and ZnSe. We also observe dehydrogenation of the Zn(O,S) buffer layer after Ar(+) ion treatment...
December 7, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27934030/enhanced-photocurrents-with-zns-passivated-cu-in-ga-se-s-2-photocathodes-synthesized-using-a-nonvacuum-process-for-solar-water-splitting
#15
Sang Youn Chae, Se Jin Park, Sung Gyu Han, Hyejin Jung, Chae-Woong Kim, Chaehwan Jeong, Oh-Shim Joo, Byoung Koun Min, Yun Jeong Hwang
Chalcopyrite Cu(In,Ga)(Se,S)2 (CIGS) semiconductors are potential candidates for use in photoelectrochemical (PEC) hydrogen generation due to their excellent optical absorption properties and high conduction band edge position. In the present research, CIGS thin film was successfully prepared on a transparent substrate (F:SnO2 glass) using a solution-based process and applied for a photocathode in solar water splitting, which shows control of the surface state associated with sulfurization/selenization process significantly influences on the PEC activity...
December 7, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27933923/enantioselective-rhodium-catalyzed-allylic-alkylation-of-prochiral-%C3%AE-%C3%AE-disubstituted-aldehyde-enolates-for-the-construction-of-acyclic-quaternary-stereogenic-centers
#16
Timothy B Wright, P Andrew Evans
A highly enantioselective rhodium-catalyzed allylic alkylation of prochiral α,α-disubstituted aldehyde enolates with allyl benzoate is described. This protocol provides a novel approach for the synthesis of acyclic quaternary carbon stereogenic centers and it represents the first example of the direct enantioselective alkylation of an aldehyde enolate per se. The versatility of the α-quaternary aldehyde products is demonstrated through their conversion to a variety of useful motifs applicable to target-directed synthesis...
November 30, 2016: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/27933455/exploration-of-genetic-and-phenotypic-diversity-within-saccharomyces-uvarum-for-driving-strain-improvement-in-winemaking
#17
Alexandra Verspohl, Lisa Solieri, Paolo Giudici
The selection and genetic improvement of wine yeast is an ongoing process, since yeast strains should match new technologies in winemaking to satisfy evolving consumer preferences. A large genetic background is the necessary starting point for any genetic improvement programme. For this reason, we collected and characterized a large number of strains belonging to Saccharomyces uvarum. In particular, 70 strains were isolated from cold-stored must samples: they were identified and compared to S. uvarum strains originating from different collections, regarding fermentation profile, spore viability and stress response...
December 8, 2016: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27933450/effects-of-exercise-intervention-in-breast-cancer-patients-is-mobile-health-mhealth-with-pedometer-more-effective-than-conventional-program-using-brochure
#18
Kyeong Eun Uhm, Ji Sung Yoo, Seung Hyun Chung, Jong Doo Lee, Ilkyun Lee, Joong Il Kim, Se Kyung Lee, Seok Jin Nam, Yong Hyun Park, Ji Youl Lee, Ji Hye Hwang
PURPOSE: To investigate and compare the effects of mobile health (mHealth) and pedometer with conventional exercise program using a brochure on physical function and quality of life (QOL). METHODS: The study was a prospective, quasi-randomized multicenter trial where 356 patients whose cancer treatment had been terminated were enrolled. All patients were instructed to perform a 12-week regimen of aerobic and resistance exercise. The mHealth group received a pedometer and a newly developed smartphone application to provide information and monitor the prescribed exercises...
December 8, 2016: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/27933359/raccoons-procyon-lotor-as-sentinels-of-trace-element-contamination-and-physiological-effects-of-exposure-to-coal-fly-ash
#19
Felipe Hernández, Ricki E Oldenkamp, Sarah Webster, James C Beasley, Lisa L Farina, Samantha M Wisely
Anthropogenic pollutants disrupt global biodiversity, and terrestrial sentinels of pollution can provide a warning system for ecosystem-wide contamination. This study sought to assess whether raccoons (Procyon lotor) are sentinels of local exposure to trace element contaminants at a coal fly ash site and whether exposure resulted in health impairment or changes in the intestinal helminth communities. We compared trace element accumulation and the impact on health responses and intestinal helminth communities of raccoons inhabiting contaminated and reference sites of the U...
December 8, 2016: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27933212/spontaneous-destructive-periodontitis-and-skeletal-bone-damage-in-transgenic-mice-carrying-a-human-shared-epitope-coding-hla-drb1-allele
#20
Prashasnika Gehlot, Sarah L Volk, Hector F Rios, Karl J Jepsen, Joseph Holoshitz
OBJECTIVE: Shared epitope (SE)-coding DRB1 alleles are associated with bone erosion in several diseases, including rheumatoid arthritis (RA) and periodontal disease (PD), but the underlying mechanism is unknown. We have recently identified the SE as an osteoclast-activating ligand. To better understand the biological effects of the SE in vivo, here we sought to determine whether it can facilitate spontaneous bone damage in naïve mice. METHODS: 3-month old naïve transgenic mice that carry the human SE-coding allele DRB1*04:01, or a SE-negative allele DRB1*04:02 were studied...
2016: RMD Open
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