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https://www.readbyqxmd.com/read/28928541/morphological-and-functional-analyses-of-the-tight-junction-in-the-palatal-epithelium-of-mouse
#1
Noriko Shiotsu, Tadafumi Kawamoto, Mariko Kawai, Mika Ikegame, Yasuhiro Torii, Hiroyuki Sasaki, Toshio Yamamoto
Tight junction (TJ) is one of the cell-cell junctions and known to have the barrier and fence functions between adjacent cells in both simple and stratified epithelia. We examined the distribution pattern, constitutive proteins, and permeability of TJ in the stratified squamous epithelium of the palatal mucosa of mice. Ultrastructural observations based on the ultrathin section and freeze-fracture methods revealed that poorly developed TJs are located at the upper layer of the stratum granulosum. The positive immunofluorescence of occludin (OCD), claudin (CLD)-1 and -4 were localized among the upper layer of the stratum granulosum showing a dot-like distribution pattern...
August 25, 2017: Acta Histochemica et Cytochemica
https://www.readbyqxmd.com/read/28927432/deer-presence-rather-than-abundance-determines-the-population-density-of-the-sheep-tick-ixodes-ricinus-in-dutch-forests
#2
Tim R Hofmeester, Hein Sprong, Patrick A Jansen, Herbert H T Prins, Sipke E van Wieren
BACKGROUND: Understanding which factors drive population densities of disease vectors is an important step in assessing disease risk. We tested the hypothesis that the density of ticks from the Ixodes ricinus complex, which are important vectors for tick-borne diseases, is determined by the density of deer, as adults of these ticks mainly feed on deer. METHODS: We performed a cross-sectional study to investigate I. ricinus density across 20 forest plots in the Netherlands that ranged widely in deer availability to ticks, and performed a deer-exclosure experiment in four pairs of 1 ha forest plots in a separate site...
September 19, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28926989/tech-savvy-beef-cattle-how-heifers-respond-to-moving-virtual-fence-lines
#3
Dana L M Campbell, Jim M Lea, William J Farrer, Sally J Haynes, Caroline Lee
Global Positioning System (GPS)-based virtual fences offer the potential to improve the management of grazing animals. Prototype collar devices utilising patented virtual fencing algorithms were placed on six Angus heifers in a 6.15 hectare paddock. After a "no fence" period, sequential, shifting virtual fences restricted the animals to 40%, 60%, and 80% of the paddock area widthways and 50% lengthways across 22 days. Audio cues signaled the virtual boundary, and were paired with electrical stimuli if the animals continued forward into the boundary...
September 18, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/28924314/comparison-between-standing-broad-jump-test-and-wingate-test-for-assessing-lower-limb-anaerobic-power-in-elite-sportsmen
#4
Anup Krishnan, Deep Sharma, Madhu Bhatt, Apoorv Dixit, P Pradeep
BACKGROUND: Lower limb explosive power is an important motor quality for sporting performance and indicates use of anaerobic energy systems like stored ATP and Creatine phosphate system. Weightlifting, Fencing and Wrestling use it for monitoring and identification of potential sportsmen. The Wingate test and Standing Broad Jump (SBJ) test are reliable and accurate tests for its assessment. This study conducted on elite Indian sportsmen tries to analyse feasibility of use of the SBJ test in sports and military medicine when Wingate test is impractical...
April 2017: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/28918095/accessibility-and-usability-of-parks-and-playgrounds
#5
Meredith A Perry, Hemakumar Devan, Harry Fitzgerald, Karen Han, Li-Ting Liu, Jack Rouse
BACKGROUND: Public parks and playgrounds are an environment for leisure activity, which all generations can enjoy at low or no financial cost. Evaluating the accessibility and usability of parks and playgrounds is crucial because their design, environment (natural and built) and safety could restrict participation of persons with disabilities. OBJECTIVE: To evaluate the accessibility and usability of 21 public parks and playgrounds in three metropolitan cities of New Zealand...
September 8, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28913764/drivers-challenges-and-opportunities-of-forage-technology-adoption-by-smallholder-cattle-households-in-cambodia
#6
K Ashley, S Wilson, J R Young, H P Chan, S Vitou, S Suon, P A Windsor, R D Bush
Forage technology has been successfully introduced into smallholder cattle systems in Cambodia as an alternative feed source to the traditional rice straw and native pastures, improving animal nutrition and reducing labour requirements of feeding cattle. Previous research has highlighted the positive impacts of forage technology including improved growth rates of cattle and household time savings. However, further research is required to understand the drivers, challenges and opportunities of forage technology for smallholder cattle households in Cambodia to facilitate widespread adoption and identify areas for further improvement...
September 14, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28912508/use-of-anthropogenic-linear-features-by-two-medium-sized-carnivores-in-reserved-and-agricultural-landscapes
#7
Georgina E Andersen, Christopher N Johnson, Leon A Barmuta, Menna E Jones
Many carnivores are threatened by habitat loss and fragmentation. These changes create linear features and habitat edges that can facilitate foraging and/or travel. To understand the significance of anthropogenic linear features in the ecology of carnivores, fine-scaled studies are needed. We studied two medium-sized carnivores: the endangered Tasmanian devil (Sarcophilus harrisii) and the near threatened spotted-tailed quoll (Dasyurus maculatus), in a mixed landscape of conservation and agricultural land. Using GPS tracking, we investigated their use of intact habitat versus linear features such as roads, fences and the pasture/cover interface...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28912255/sex-hormones-and-the-development-of-sexual-size-dimorphism-dihydrotestosterone-inhibits-growth-in-a-female-larger-lizard-sceloporus-undulatus
#8
Nicholas B Pollock, Stephanie Feigin, Marko Drazenovic, Henry B John-Alder
Sexual differences in adult body size (sexual size dimorphism; SSD) and color (sexual dichromatism) are widespread, and both male- and female-biased dimorphisms are observed even among closely related species. A growing body of evidence indicates testosterone (T) can regulate growth, thus the development of SSD, and sexual dichromatism. However, the mechanism(s) underlying these effects are conjectural, including possible conversions of T to estradiol (E2) or 5 α-dihydrotestosterone (DHT). In the present study, we hypothesized that effects of T are physiological responses mediated by androgen receptors, and we tested two specific predictions: 1) that DHT would mimic effects of T by inhibiting growth and enhancing coloration, and 2) that removal of endogenous T via surgical castration would stimulate growth...
September 14, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28904779/discriminating-patterns-and-drivers-of-multiscale-movement-in-herpetofauna-the-dynamic-and-changing-environment-of-the-mojave-desert-tortoise
#9
Giancarlo Sadoti, Miranda E Gray, Matthew L Farnsworth, Brett G Dickson
Changes to animal movement in response to human-induced changes to the environment are of growing concern in conservation. Most research on this problem has focused on terrestrial endotherms, but changes to herpetofaunal movement are also of concern given their limited dispersal abilities and specialized thermophysiological requirements. Animals in the desert region of the southwestern United States are faced with environmental alterations driven by development (e.g., solar energy facilities) and climate change...
September 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28902120/competition-intensity-and-fatigue-in-elite-fencing
#10
Anthony N Turner, Liam Kilduff, Geoff Marshall, James Phillips, Angelo Noto, Conor Buttigieg, Marcela Gondek, Frank Hills, Lygeri Dimitriou
As yet, no studies have characterised fencing competitions. Therefore in elite male foilists and across two competitions, we investigated their countermovement jump (CMJ) height, testosterone (T), cortisol (C), alpha-amylase (AA), immunoglobulin A (IgA), heart rate (HR), blood lactate (BL) and rating of perceived exertion (RPE). Average (± SD) scores for RPE, BL and HR (average, max and percentage of time ≥ 80% HRmax) were highest in the knockout bouts compared to poules (8.5 ± 1.3 vs. 5.7 ± 1.3, 3.6 ± 1...
September 7, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28900327/metastatic-ewing-s-sarcoma-revisiting-the-evidence-on-the-fence
#11
REVIEW
Nehal Khanna, Avinash Pandey, Jyoti Bajpai
Metastatic Ewing's sarcoma is a challenging disease for oncology care providers with wide spectrum of disease at presentation, widely varying approach to the treatment and varied outcomes. The paucity of randomized evidence is a barrier in developing a consensus. This perspective provides the evidence "for and against" the benefit of aggressive approach including local and systemic therapy in patients presenting with metastatic Ewing's sarcoma and provide general recommendations so as to help select patients who will benefit with definitive intent treatment and also, avoid aggressive approach in patients with dismal outcome...
April 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28899157/don-t-fence-me-in-what-is-american-about-american-psychoanalysis
#12
Gavin Mullen
No abstract text is available yet for this article.
December 2016: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28898110/the-perception-of-malaysian-pedestrians-towards-the-use-of-footbridges
#13
Razi Hasan, Madzlan Napiah
OBJECTIVE: The footbridge is a vital structure in the road network and a cornerstone among crossing facilities. Yet, it suffers from the low usage by pedestrians as they try to cross the street on the level. This study is aimed to analyse the perceptions of Malaysian pedestrians towards the use of footbridges with the consideration of different factors. METHOD: The study was carried out by collecting data from the field observation and the questionnaire distribution on the street among the public...
September 12, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28894567/an-indicator-approach-to-capture-impacts-of-white-tailed-deer-and-other-ungulates-in-the-presence-of-multiple-associated-stressors
#14
Bernd Blossey, Andrea Dávalos, Victoria Nuzzo
Management of ungulates is contested ground that lacks stakeholder agreement on desirable population sizes and management approaches. Unfortunately, we often miss information about extent of local impacts, for example on plant communities, to guide management decisions. Typical vegetation impact assessments like the woody browse index do not assess herbaceous plants, and differences in browse severity can be a function of deer density, deer legacy effects, localized deer feeding preferences and/or differences in plant community composition...
September 2017: AoB Plants
https://www.readbyqxmd.com/read/28887825/performance-of-a-multi-leaf-collimator-system-for-mr-guided-radiation-therapy
#15
Bin Cai, Harold Li, Deshan Yang, Vivian Rodriguez, Austen Curcuru, Yuhe Wang, Jie Wen, Rojano Kashani, Sasa Mutic, Olga Green
PURPOSE: To investigate and characterize the performance of a Multi Leaf Collimator (MLC) designed for Cobalt-60 based MR-guided radiation therapy system in a 0.35T magnetic field. METHODS: The MLC design and unique assembly features in the ViewRay MRIdian system were first reviewed. The RF cage shielding of MLC motor and cables were evaluated using ACR phantoms with real time imaging and quantified by signal-to-noise ratio. The dosimetric characterizations, including the leaf transmission, leaf penumbra, tongue and groove effect, were investigated using radiosensitive films...
September 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/28883651/the-role-of-transcriptional-factor-p63-in-regulation-of-epithelial-barrier-and-ciliogenesis-of-human-nasal-epithelial-cells
#16
Yakuto Kaneko, Takayuki Kohno, Takuya Kakuki, Ken-Ichi Takano, Noriko Ogasawara, Ryo Miyata, Shin Kikuchi, Takumi Konno, Tsuyoshi Ohkuni, Ryoto Yajima, Akito Kakiuchi, Shin-Ichi Yokota, Tetsuo Himi, Takashi Kojima
Disruption of nasal epithelial tight junctions (TJs) and ciliary dysfunction are found in patients with chronic rhinosinusitis (CRS) and nasal polyps (NPs), along with an increase of p63-positive basal cells and histone deacetylase (HDAC) activity. To investigate these mechanisms, primary cultures of HNECs transfected with human telomerase reverse transcriptase (hTERT-HNECs) were transfected with siRNAs of TAp63 and ΔNp63, treated with the NF-kB inhibitor curucumin and inhibitors of HDACs, and infected with respiratory syncytial virus (RSV)...
September 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28873022/seroprevalence-of-leptospirosis-brucellosis-and-q-fever-in-a-wild-red-deer-cervus-elaphus-population-kept-in-a-fenced-reserve-in-absence-of-contact-with-livestock
#17
Jose María San-Miguel Ayanz, Francisco Javier Garcia-Peña, Paula García-Lunar, Luis Miguel Ortega-Mora, María José Ruano, Gema Álvarez-García, Esther Collantes-Fernández
Wildlife health is of interest for public and animal health because wild animals have been identified as important sentinels for the surveillance for zoonotic pathogens. This work investigated Brucella spp., Coxiella burnetii, and Leptospira spp. infection seroprevalence in a free-ranging red deer population. The study was conducted in a fenced reserve with controlled hunting activity in central Spain with animals that did not have any contact with livestock. Sampling was performed at two time points before and 5 years after the implementation of new management measures, including a reduction in the red deer population in the reserve...
September 5, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28870535/historical-overview-of-infantile-visceral-leishmaniasis-in-el-agamy-alexandria-egypt
#18
REVIEW
Hala A Kassem, John C Beier, Bahira M El Sawaf
Infantile visceral leishmaniasis (IVL) is considered a rare and neglected disease in Egypt. An outbreak of the disease in El Agamy, Alexandria occurred in 1982 although the disease was previously reported 80 years before. Epidemiological and entomological studies were conducted ever since the 1982 outbreak to identify human cases, the parasite, reservoir host and the sand fly vector. Leishmania infantum MON-98, a new and unique zymodeme, was responsible of the disease. Stray dogs acted as the reservoir host and Phlebotomus langeroni was the proven vector...
September 8, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28869917/response-of-soil-methane-uptake-to-simulated-nitrogen-deposition-and-grazing-management-across-three-types-of-steppe-in-inner-mongolia-china
#19
Xianglan Li, Hong He, Wenping Yuan, Linghao Li, Wenfang Xu, Wei Liu, Huiqiu Shi, Longyu Hou, Jiquan Chen, Zhiping Wang
The response of soil methane (CH4) uptake to increased nitrogen (N) deposition and grazing management was studied in three types of steppe (i.e., meadow steppe, typical steppe, and desert steppe) in Inner Mongolia, China. The experiment was designed with four simulated N deposition rates such as 0, 50, 100, and 200kgNha(-1), respectively, under grazed and fenced management treatments. Results showed that the investigated steppes were significant sinks for CH4, with an uptake flux of 1.12-3.36kgha(-1) over the grass growing season and that the magnitude of CH4 uptake significantly (P<0...
August 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28863451/intensive-management-and-natural-genetic-variation-in-red-deer-cervus-elaphus
#20
Juan A Galarza, Beatriz Sánchez-Fernández, Paulino Fandos, Ramón Soriguer
The current magnitude of big-game hunting has outpaced the natural growth of populations, making artificial breeding necessary to rapidly boost hunted populations. In this study, we evaluated if the rapid increase of red deer (Cervus elaphus) abundance, caused by the growing popularity of big-game hunting, has impacted the natural genetic diversity of the species. We compared several genetic diversity metrics between 37 fenced populations subject to intensive management and 21 wild free-ranging populations...
July 1, 2017: Journal of Heredity
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