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Infections in obstetrics

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https://www.readbyqxmd.com/read/28719309/seroprevalence-of-toxoplasma-gondii-infection-in-refugee-and-migrant-pregnant-women-along-the-thailand-myanmar-border
#1
Bert J D van Enter, Yee-Ling Lau, Clare L Ling, Wanitda Watthanaworawit, Yaowalark Sukthana, Wenn-Chyau Lee, François Nosten, Rose McGready
Toxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samples from first antenatal screen in 2014-2015 was tested for Toxoplasma IgG and IgM antibodies. Seroprevalence of Toxoplasma infection was 31.7% (95% confidence interval = 25.6-38.4). Avidity testing in the three positive IgM cases indicated all were past infections...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718408/a-common-clinical-dilemma-management-of-persistent-hrhpv-infection
#2
Yifan Meng, Ding Ma, Peng Wu
Persistent infection with high-risk human papillomavirus (hrHPV) is a key step in the development of cervical cancer. However, making clinical decisions about how to deal with these cases has become a challenge for obstetrics and gynecology (Ob/Gyn) practitioners. Here, we review the latest research findings and propose possible solutions for the management of persistent hrHPV infections.
May 2017: Trends in Cancer
https://www.readbyqxmd.com/read/28713513/the-prevalence-and-risk-factors-of-group-b-streptococcus-colonization-in-iranian-pregnant-women
#3
Roksana Darabi, Sima Tadi, Mitra Mohit, Erfan Sadeghi, Gita Hatamizadeh, Bahareh Kardeh, Mina Etminan-Bakhsh, Yekta Parsa
BACKGROUND: Group B Streptococcus (GBS) is a leading cause of serious neonatal infections. Although great progress has been made in preventing prenatal GBS, its colonization rate in different regions of Iran remains unknown. AIM: To determine GBS colonization prevalence and its risk factors among Iranian pregnant women. METHODS: This prospective cross-sectional study was performed on 186 pregnant women, who attended Boo-Ali hospital which is affiliated with Islamic Azad University in Tehran, Iran, from March 2014 to June 2015...
May 2017: Electronic Physician
https://www.readbyqxmd.com/read/28706365/obstetric-outcome-in-women-with-chronic-liver-disease
#4
Pinky Jena, C N Sheela, Rao Preethi Venkatachala, Harshad Devarbhavi
AIM: This study determines the prevalence, causes and outcome of pregnancy in women with chronic liver diseases in a tertiary level teaching institute in Southern India. METHODS: Retrospective analysis of case records was carried out between December 2010 and May 2015 in the departments of Obstetrics and Gynecology and Gastroenterology including pregnant women diagnosed to have chronic liver diseases prenatally or during pregnancy. RESULTS: The frequency of chronic liver disease in pregnancy was 50 among 10,823 deliveries (0...
August 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28699385/intravaginal-practices-among-young-hiv-infected-women-in-lusaka-zambia
#5
Maureen Chisembele, Violeta J Rodriguez, Megan R Brown, Deborah L Jones, Maria L Alcaide
Intravaginal practices (IVP) are linked to bacterial vaginosis (BV), obstetric/gynecological complications, and HIV. Late adolescent and young adult (LAYA) women in Zambia have high rates of HIV. Adult and mature (AM) HIV-infected women in Zambia engage in IVP for hygiene, health, and sexuality reasons; however, to our knowledge, IVP use among LAYA women has not been examined. This study compares IVP use between LAYA and AM women to identify age-specific factors to target when developing IVP reduction interventions for LAYA women...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28695344/genital-tract-fistula-a-case-series-from-a-tertiary-centre-in-south-africa
#6
Thinagrin Dhasarathun Naidoo, Jagidesa Moodley, Saloshni Naidoo
INTRODUCTION AND HYPOTHESIS: We describe the demographic profile, aetiology, management and surgical outcomes in women with genital tract fistula presenting to a tertiary urogynaecology unit. METHODS: This retrospective audit included 87 patients managed in our unit between 2008 and 2015. Frequencies and means with standard deviations are presented for categorical and continuous data. Continuous dependent variables are categorized as above or below the median for bivariate analyses performed using the chi-squared test (α = 0...
July 10, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28693123/clinical-chorioamnionitis-at-term-viii-a-rapid-mmp-8-test-for-the-identification-of-intra-amniotic-inflammation
#7
Noppadol Chaiyasit, Roberto Romero, Piya Chaemsaithong, Nikolina Docheva, Gaurav Bhatti, Juan Pedro Kusanovic, Zhong Dong, Lami Yeo, Percy Pacora, Sonia S Hassan, Offer Erez
OBJECTIVE: Clinical chorioamnionitis is the most common infection/inflammatory process diagnosed in labor and delivery units worldwide. The condition is a syndrome that can be caused by (1) intra-amniotic infection, (2) intra-amniotic inflammation without demonstrable microorganisms (i.e. sterile intra-amniotic inflammation), and (3) maternal systemic inflammation that is not associated with intra-amniotic inflammation. The presence of intra-amniotic inflammation is a risk factor for adverse maternal and neonatal outcomes in a broad range of obstetrical syndromes that includes clinical chorioamnionitis at term...
June 24, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28690864/surgical-site-infections-after-cesarean-delivery-epidemiology-prevention-and-treatment
#8
REVIEW
Tetsuya Kawakita, Helain J Landy
Cesarean delivery (CD) is one of the most common procedures performed in the United States, accounting for 32% of all deliveries. Postpartum surgical site infection (SSI), wound infection and endometritis is a major cause of prolonged hospital stay and poses a burden to the health care system. SSIs complicate a significant number of patients who undergo CD - 2-7% will experience sound infections and 2-16% will develop endometritis. Many risk factors for SSI have been described. These include maternal factors (such as tobacco use; limited prenatal care; obesity; corticosteroid use; nulliparity; twin gestations; and previous CD), intrapartum and operative factors (such as chorioamnionitis; premature rupture of membranes; prolonged rupture of membranes; prolonged labor, particularly prolonged second stage; large incision length; subcutaneous tissue thickness > 3 cm; subcutaneous hematoma; lack of antibiotic prophylaxis; emergency delivery; and excessive blood loss), and obstetrical care on the teaching service of an academic institution...
2017: Maternal Health, Neonatology and Perinatology
https://www.readbyqxmd.com/read/28681107/comparison-of-maternal-and-fetal-complications-in-elective-and-emergency-cesarean-section-a-systematic-review-and-meta-analysis
#9
Xiao-Jing Yang, Shan-Shan Sun
BACKGROUND: Though the same types of complication were found in both elective cesarean section (ElCS) and emergence cesarean section (EmCS), the aim of this study is to compare the rates of maternal and fetal morbidity and mortality between ElCS and EmCS. METHODS: Full-text articles involved in the maternal and fetal complications and outcomes of ElCS and EmCS were searched in multiple database. Review Manager 5.0 was adopted for meta-analysis, sensitivity analysis, and bias analysis...
July 5, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28672754/postpartum-infection-in-relation-to-maternal-characteristics-obstetric-interventions-and-complications
#10
Daniel Axelsson, Jan Brynhildsen, Marie Blomberg
The purpose was to evaluate the association between maternal characteristics, obstetrical interventions/complications and postpartum wound infections (WI), urinary tract infection (UTI) and endometritis. Furthermore, this study aimed to determine the time from delivery to onset of infections after discharge from the hospital. Three large Swedish Medical Health Registers were scrutinized for the period 2005-2012. A total of 582,576 women had 795,072 deliveries. Women with diagnosis codes for WIs, UTIs or endometritis, from delivery to 8 weeks postpartum, were compared to non-infected women...
June 26, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28672752/clinical-chorioamnionitis-at-term-viii-a-rapid-mmp-8-test-for-the-identification-of-intra-amniotic-inflammation
#11
Noppadol Chaiyasit, Roberto Romero, Piya Chaemsaithong, Nikolina Docheva, Gaurav Bhatti, Juan Pedro Kusanovic, Zhong Dong, Lami Yeo, Percy Pacora, Sonia S Hassan, Offer Erez
OBJECTIVE: Clinical chorioamnionitis is the most common infection/inflammatory process diagnosed in labor and delivery units worldwide. The condition is a syndrome that can be caused by (1) intra-amniotic infection, (2) intra-amniotic inflammation without demonstrable microorganisms (i.e. sterile intra-amniotic inflammation), and (3) maternal systemic inflammation that is not associated with intra-amniotic inflammation. The presence of intra-amniotic inflammation is a risk factor for adverse maternal and neonatal outcomes in a broad range of obstetrical syndromes that includes clinical chorioamnionitis at term...
July 26, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28670748/somanz-guidelines-for-the-investigation-and-management-sepsis-in-pregnancy
#12
Lucy Bowyer, Helen L Robinson, Helen Barrett, Timothy M Crozier, Michelle Giles, Irena Idel, Sandra Lowe, Karin Lust, Catherine A Marnoch, Mark R Morton, Joanne Said, Maggie Wong, Angela Makris
SOMANZ (Society of Obstetric Medicine Australia and New Zealand) has written a guideline to provide evidence-based guidance for the investigation and care of women with sepsis in pregnancy or the postpartum period. The guideline is evidence-based and incorporates recent changes in the definition of sepsis. The etiology, investigation and treatment of bacterial, viral and non-infective causes of sepsis are discussed. Obstetric considerations relevant to anaesthetic and intensive care treatment in sepsis are also addressed...
July 3, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28663682/hepatitis-e-virus-induced-acute-liver-failure-with-scrub-typhus-coinfection-in-a-pregnant-woman
#13
Nipun Verma, Megha Sharma, Manisha Biswal, Sunil Taneja, Nitya Batra, Abhay Kumar, Radha K Dhiman
Coinfections contribute significantly to diagnostic challenges of acute febrile illnesses, especially in endemic areas. The confusion caused by overlapping clinical features impedes timely management. Herein, we report an unusual, previously unreported case of a pregnant woman suffering from a coinfection of scrub typhus and hepatitis E virus. A 25-year-old, 31-week pregnant woman presented with jaundice for 5 days and altered sensorium for 2 days. She had features of both viral acute liver failure (ALF) and tropical infections mimicking ALF, including hyperbilirubinemia, coagulopathy, anemia, thrombocytopenia, intravascular hemolysis, and hepatosplenomegaly...
June 2017: Journal of Clinical and Experimental Hepatology
https://www.readbyqxmd.com/read/28661549/hepatitis-c-in-pregnancy-review-of-current-knowledge-and-updated-recommendations-for-management
#14
Charlotte M Page, Brenna L Hughes, Eleanor H J Rhee, Jeffrey A Kuller
Importance: An estimated 1% to 2.5% of pregnant women in the United States are infected with hepatitis C virus (HCV), which carries approximately a 6% risk of mother-to-infant transmission. Objectives: The aims of this article are to review the current evidence on HCV in pregnancy and to provide updated recommendations for management. Evidence Acquisition: Original research articles, review articles, and guidelines on HCV in general and specifically in pregnancy were reviewed, as were drug safety profiles from the Food and Drug Administration...
June 2017: Obstetrical & Gynecological Survey
https://www.readbyqxmd.com/read/28658852/severe-puerperal-sepsis-a-simmering-menace
#15
Sheeba Marwah, Sonam R Topden, Manjula Sharma, Ritin Mohindra, Pratima Mittal
INTRODUCTION: Even decades after the development of effective low-cost antibiotics, sepsis persists as the foremost cause of preventable maternal death worldwide. In developing countries like India, where the paramount impediment to intervention is poverty, maternal mortality due to sepsis is a continuing representation of maternal health inequality. AIM: To determine the incidence, risk factors and mortality in women presenting with puerperal sepsis in a tertiary care health facility in India...
May 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28652788/economic-and-organizational-sustainability-of-a-negative-pressure-portable-device-for-the-prevention-of-surgical-site-complications
#16
Emanuela Foglia, Lucrezia Ferrario, Elisabetta Garagiola, Giuseppe Signoriello, Gianluca Pellino, Davide Croce, Silvestro Canonico
PURPOSE: Surgical-site complications (SSCs) affect patients' clinical pathway, prolonging their hospitalization and incrementing their management costs. The present study aimed to assess the economic and organizational implications of a portable device for negative-pressure wound therapy (NPWT) implementation, compared with the administration of pharmacological therapies alone for preventing surgical complications in patients undergoing general, cardiac, obstetrical-gynecological, or orthopedic surgical procedures...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28650528/urinary-diversions-in-low-resource-settings
#17
Jeffrey P Wilkinson
Obstetric fistula is a devastating consequence of poorly attended childbirth which occurs almost exclusively in low resource settings. Most women with fistula can be cured or significantly improved by one or more vaginal surgeries. The last resort for women with otherwise incurable obstetric fistula is urinary diversion. The ileal conduit urinary diversion was the procedure considered by the authors of the accompanying article (Walker et al BJOG). Under optimal conditions, any urinary diversion is fraught with numerous potential risks...
June 26, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28648621/differential-expression-of-circulating-th1-th2-th17-cytokines-in-serum-of-chlamydia-trachomatis-infected-women-undergoing-incomplete-spontaneous-abortion
#18
Priya Prasad, Namita Singh, Banashree Das, Sheikh Raisuddin, Mridu Dudeja, Sangita Rastogi
The study aimed to elucidate role of Th1/Th2/Th17 cytokines in the immunopathogenesis of spontaneous abortion in Chlamydia trachomatis (Ct)-positive first-trimester aborters. Endometrial curettage tissue and serum were collected from 145 aborters (spontaneous abortion (SA) group, n = 85; recurrent miscarriage (RM) group, n = 60) and 120 controls attending Department of Obstetrics & Gynecology at Safdarjung hospital, New Delhi (India). Polymerase chain reaction was used to detect Ct plasmid/MOMP, while commercial cytometric bead array kit was utilized to estimate circulating serum cytokines...
June 23, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28646987/state-based-perinatal-quality-collaboratives-pursuing-improvements-in-perinatal-health-outcomes-for-all-mothers-and-newborns
#19
Munish Gupta, Edward F Donovan, Zsakeba Henderson
State-based perinatal quality collaboratives (SPQC) have become increasingly widespread in the United States. Whereas the first was launched in 1997, today over 40 states have SPQCs that are actively working or are in development. Despite great variability in the structure and function of SPQCs among states, many have seen their efforts lead to significant improvements in the care of mothers and newborns. Clinical topics targeted by SPQCs have included nosocomial infection in newborns, human milk use, neonatal abstinence syndrome, early term deliveries without a medical indication, maternal hemorrhage, and maternal hypertension, among others...
April 2017: Seminars in Perinatology
https://www.readbyqxmd.com/read/28644337/committee-opinion-no-705-mental-health-disorders-in-adolescents
#20
(no author information available yet)
Mental health disorders in adolescence are a significant problem, relatively common, and amenable to treatment or intervention. Obstetrician-gynecologists who see adolescent patients are highly likely to see adolescents and young women who have one or more mental health disorders. Some of these disorders may interfere with a patient's ability to understand or articulate her health concerns and appropriately adhere to recommended treatment. Some disorders or their treatments will affect the hypothalamic-pituitary-gonadal axis, causing anovulatory cycles and various menstrual disturbances...
July 2017: Obstetrics and Gynecology
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