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High-risk obstetrics, hypertension,malformations

Y Xiong, H X Xia, Y S Wang, X L Lin, T T Zhu, Y Zhao, X T Li
Objective: To explore the high risk factors of stillbirth. Methods: 176 cases of stillbirth were collected in the Obstetrics and Gynecology Hospital of Fudan University from January 1(st), 2010 to December 31(st), 2016. All cases were analyzed retrospectively, including general profile, high risk factors of stillbirth in different years and pregnancy periods. Results: (1) The incidence of stillbirth was 0.178%(176/98 785). Stillbirth occured mostly at 28-28(+6) gestational weeks (10.8%,19/176), and the second peak was 29-29(+6) weeks(10...
December 25, 2017: Zhonghua Fu Chan Ke za Zhi
Q T Ou, J K Lu, J Zhang, Y Chen, Q Li, J L Zhang
Objective: To investigate the perinatal outcome, risk factors and long-term outcome of pregnancy complicated with pulmonary arterial hypertension(PAH) and congenital heart diseases (CHD). Methods: Clinical data of 110 pregnant women who were diagnosed as PAH-CHD were retrospectively analyzed in the Department of Obstetrics and Gynecology and Surgical Intensive Care Unit at Beijing Anzhen Hospital from 2004 to 2013. The survival and treatment status were followed up. Results: 110 subjects consisted of 11 mild PAH, 33 moderate and 66 severe ones...
November 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Jiabi Qin, Xiaoying Liu, Xiaoqi Sheng, Hua Wang, Shiyou Gao
OBJECTIVE: To determine whether there are any increases in pregnancy-related complications and adverse pregnancy outcomes in singleton pregnancies after assisted reproductive technology (ART) compared with those conceived naturally. DESIGN: Meta-analysis. SETTING: University-affiliated teaching hospital. PATIENT(S): Singleton pregnancies conceived with ART and naturally. INTERVENTION(S): PubMed, Google Scholar, Cochrane Libraries and Chinese database were searched through March 2015 to identify studies that met pre-stated inclusion criteria...
January 2016: Fertility and Sterility
Luz Viale, John Allotey, Fiona Cheong-See, David Arroyo-Manzano, Dougall Mccorry, Manny Bagary, Luciano Mignini, Khalid S Khan, Javier Zamora, Shakila Thangaratinam
BACKGROUND: Antenatal care of women with epilepsy is varied. The association of epilepsy and antiepileptic drug exposure with pregnancy outcomes needs to be quantified to guide management. We did a systematic review and meta-analysis to investigate the association between epilepsy and reproductive outcomes, with or without exposure to antiepileptic drugs. METHODS: We searched MEDLINE, Embase, Cochrane, AMED, and CINAHL between Jan 1, 1990, and Jan 21, 2015, with no language or regional restrictions, for observational studies of pregnant women with epilepsy, which assessed the risk of obstetric complications in the antenatal, intrapartum, or postnatal period, and any neonatal complications...
November 7, 2015: Lancet
Xiao-Lin Luo, Wei-Yuan Zhang
BACKGROUND: No national research on maternal and fetal complications and outcomes has been carried out in the mainland of China in recent years. This study was to provide a scientific basis for better control of obstetrical and neonatal diseases and better allocation of medical resources by analyzing the epidemiological characteristics of obstetrical diseases in the mainland of China. METHODS: Hospitalized obstetrical cases from 19 tertiary and 20 secondary hospitals in 14 provinces (nationally representative) during the period January 1, 2011 to December 31, 2011 were randomly selected...
May 5, 2015: Chinese Medical Journal
Zilma Silveira Nogueira Reis, Eura Martins Lage, Regina Amelia Lopes Pessoa Aguiar, Juliano de Souza Gaspar, Gabriela Luiza Nogueira Vitral, Eliana Goncalves Machado
PURPOSE: To analyze the relationships among gestational risk, type of delivery and immediate maternal and neonatal repercussions. METHODS: A retrospective cohort study based on secondary data was conducted in a university maternity hospital. A total of 1606 births were analyzed over a 9-month period. Epidemiological, clinical, obstetric and neonatal characteristics were compared according to the route of delivery and the gestational risk characterized on the basis of the eligibility criteria for high clinical risk...
February 2014: Revista Brasileira de Ginecologia e Obstetrícia
Marielle Morissens, Pierre Viart, Laura Tecco, Pierre Wauthy, Simone Michiels, Hugues Dessy, Sophie Malekzadeh Milani, Thierry Verbeet, Jose Castro Rodriguez
AIM: Women with congenital heart disease are often considered to be restricted in their obstetrical life and even their marital life. Our single-centre study aimed to determine the real-life situation of these women with regard to successful family life and any pregnancy complications they may experience. METHODS: From our database of adults with congenital heart disease, 160 of 178 women completed a questionnaire and had their files reviewed. They were classified into three groups according to their pregnancy risk - "good condition" group, no pregnancy restriction; "at-risk" group, pregnancy allowed with close follow-up at a tertiary centre; and "contraindicated" group, pregnancy inadvisable...
February 2013: Cardiology in the Young
Jama Fathia E Al
OBJECTIVE: To assess the incidence of antenatal and intrapartum and perinatal outcomes in grandmultiparae in an affluent society with available modern perinatal care. STUDY DESIGN: A case-control study in a tertiary referral hospital in Eastern Saudi Arabia of 2,122 grandmultiparae was undertaken. Each patient was compared with an age-matched multipara who delivered during the 10-year study period. Data was obtained from the computerized hospital information systems and their statistical analysis performed to determine the significant categorical variables...
January 2012: Journal of Reproductive Medicine
I Borthen, M G Eide, A K Daltveit, N E Gilhus
OBJECTIVE: To report the complications during pregnancy and delivery in women with epilepsy, compared with a control group without epilepsy, with special focus on potential risk factors, such as epilepsy severity and dosage of antiepileptic drugs. DESIGN: Hospital-based retrospective study. SETTING: Data from pregnancy notification forms and hospital case records. POPULATION: Women with a past or present history of epilepsy (n = 205) delivered in Bergen, Norway, in the period 1999-2006, and a matched control group of women (n = 205) without epilepsy...
July 2011: BJOG: An International Journal of Obstetrics and Gynaecology
Antonella Giancotti, Antonella Spagnuolo, Valentina D'Ambrosio, Gaia Pasquali, Brunella Muto, Francescantonio Bisogni, Renato La Torre, Maurizio Marco Anceschi, Fabrizio De Gado
INTRODUCTION: We describe a case of early and persistent reverse end-diastolic flow in the middle cerebral artery in a fetus with severe ascites. These features are associated with a rare liver malformation known as ductal plate malformation. CASE PRESENTATION: A 28-year-old Caucasian woman was referred to our high-risk obstetric unit at 24 weeks' gestation for fetal ascites detected during a routine ultrasound examination. During her hospitalization we performed medical investigations, including a fetal paracentesis, to detect the etiology of fetal ascites...
2011: Journal of Medical Case Reports
Teresa Kulie, Andrew Slattengren, Jackie Redmer, Helen Counts, Anne Eglash, Sarina Schrager
Obesity negatively impacts the health of women in many ways. Being overweight or obese increases the relative risk of diabetes and coronary artery disease in women. Women who are obese have a higher risk of low back pain and knee osteoarthritis. Obesity negatively affects both contraception and fertility as well. Maternal obesity is linked with higher rates of cesarean section as well as higher rates of high-risk obstetrical conditions such as diabetes and hypertension. Pregnancy outcomes are negatively affected by maternal obesity (increased risk of neonatal mortality and malformations)...
January 2011: Journal of the American Board of Family Medicine: JABFM
Nabila Zareen, Sonia Naqvi, Nasreen Majid, Hassan Fatima
OBJECTIVE: To determine the perinatal outcome of high risk pregnancies, in terms of perinatal mortality, Apgar score, birth weight and neonatal complications in first week after birth. STUDY DESIGN: Cohort study. PLACE AND DURATION OF STUDY: Obstetric Department of Sir Syed Trust Hospital, Karachi, from January to December 2007. METHODOLOGY: All antenatal patients attending the Outpatient Department were interviewed, after informed consent...
July 2009: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Anne Kirkeby Hansen, Kirsten Wisborg, Niels Uldbjerg, Tine Brink Henriksen
OBJECTIVE: To investigate the association between elective caesarean sections and neonatal respiratory morbidity and the importance of timing of elective caesarean sections. DESIGN: Cohort study with prospectively collected data from the Aarhus birth cohort, Denmark. SETTING: Obstetric department and neonatal department of a university hospital in Denmark. PARTICIPANTS: All liveborn babies without malformations, with gestational ages between 37 and 41 weeks, and delivered between 1 January 1998 and 31 December 2006 (34 458 babies)...
January 12, 2008: BMJ: British Medical Journal
Annunziata Lapolla, Maria Grazia Dalfrà, Graziano Di Cianni, Matteo Bonomo, Elena Parretti, Giorgio Mello et al.
BACKGROUND AND AIM: To determine pregnancy outcome in women with type 1 and type 2 diabetes. METHODS AND RESULTS: A prospective study was conducted in 33 centers in Italy between 1999 and 2003, mainly recording preterm delivery, stillbirths, neonatal mortality, congenital malformations and birthweight. Of the 668 women examined, 504 had type 1 diabetes and 164 had type 2. Pre-pregnancy counseling had been provided to 43.9% of the women who had type 1 diabetes and 29...
May 2008: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
José Villar, Guillermo Carroli, Daniel Wojdyla, Edgardo Abalos, Daniel Giordano, Hassan Ba'aqeel, Ubaldo Farnot, Per Bergsjø, Leiv Bakketeig, Pisake Lumbiganon, Liana Campodónico, Yagob Al-Mazrou, Marshall Lindheimer, Michael Kramer et al.
OBJECTIVE: Preeclampsia, gestational hypertension, and unexplained intrauterine growth restriction may have similar determinants and consequences. In this study, we compared determinants and perinatal outcomes associated with these obstetric conditions. STUDY DESIGN: We analyzed 39,615 pregnancies (data from the WHO Antenatal Care Trial), of which 2.2% were complicated by preeclampsia, 7.0% by gestational hypertension, and 8.1% by unexplained intrauterine growth restriction (ie, not associated with maternal smoking, maternal undernutrition, preeclampsia, gestational hypertension, or congenital malformations)...
April 2006: American Journal of Obstetrics and Gynecology
Mehreen Mehdi Naqvi, Azra Naseem
OBJECTIVE: To compare the complications, delivery mode and fetal outcome between elderly primigravidae and young primigravidae. DESIGN: A comparative study. PLACE AND DURATION OF STUDY: Department of Obstetrics and Gynaecology, POFs Hospital, Wah Cantt, from January 2001 to December 2002. SUBJECTS AND METHODS: One hundred and fifty six elderly primigravidae were compared with a matched pair group of younger primigravidae regarding antenatal, intrapartum and postpartum complications...
May 2004: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Eyal Sheiner, Amalia Levy, Daniel Silverberg, Tehillah S Menes, Isaac Levy, Miriam Katz, Moshe Mazor
OBJECTIVE: The purpose of this study was to investigate the pregnancy outcome of patients after bariatric surgery. STUDY DESIGN: A population-based study was performed that compared all pregnancies of patients with and without previous obesity operations between the years 1988 and 2002. Stratified analyses with the Mantel-Haenszel technique and a multiple logistic regression model were performed to control for confounders. RESULTS: Of the 159210 deliveries that were performed during the study period, 298 deliveries were to patients after bariatric operations...
May 2004: American Journal of Obstetrics and Gynecology
Alexandra Kautzky-Willer, Dagmar Bancher-Todesca
Gestational diabetes (GDM) is defined as any degree of glucose intolerance with onset or first recognition during pregnancy. GDM is becoming an increasing health problem worldwide and one of the most common complications of pregnancy. The prevalence of GDM in Central Europe is 5-7%. GDM is associated with increased feto-maternal morbidity as well as long-term complications in mothers and offspring. The key symptom of GDM is the development of diabetic fetopathy. Fetal hyperinsulinism is associated with macrosomia and a higher rate of birth injuries and caesarean sections, neonatal hypoglycemia, respiratory distress and due to fetal programming the development of the sequelae of the metabolic syndrome in childhood or adolescence...
2003: Wiener Medizinische Wochenschrift
Małgorzata Tyloch, Wiesław Szymański, Stanisław Skublicki
UNLABELLED: Pre-gestational diabetes is a serious risk factor in pregnancy and delivery. Complications during pregnancy in this group of women depend on the glycemic control and on the clinical course of diabetes. MATERIAL AND METHOD: On the period of 1991-2001, 186 pregnant women with diabetes diagnosed before pregnancy were hospitalized in Ob/Gyn Department, Medical University of Bydgoszcz. In this study, 178 deliveries and 8 abortions were analyzed. The selected glycemic control indices-GCI (General Control Index) were analyzed in diabetic women with non-complicated pregnancies and in women with complications during pregnancy...
October 2003: Ginekologia Polska
E Sheiner, I Shoham-Vardi, M Hallak, A Hadar, L Gortzak-Uzan, M Katz, M Mazor
OBJECTIVE: To determine the incidence, obstetric risk factors and pregnancy outcome of placental abruption at term. METHODS: A comparison of all singleton term deliveries (> or = 37 weeks' gestation) complicated with placental abruption to singleton term deliveries without placental abruption. Multivariate analysis was performed to investigate independent risk factors for placental abruption. RESULTS: Placental abruption complicated 0.3% of all term deliveries (n = 72,995)...
January 2003: Journal of Maternal-fetal & Neonatal Medicine
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