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membrane diffusing capacity

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https://www.readbyqxmd.com/read/29320578/the-potent-effect-of-mycolactone-on-lipid-membranes
#1
Milène Nitenberg, Anaïs Bénarouche, Ofelia Maniti, Estelle Marion, Laurent Marsollier, Julie Géan, Erick J Dufourc, Jean-François Cavalier, Stéphane Canaan, Agnès P Girard-Egrot
Mycolactone is a lipid-like endotoxin synthesized by an environmental human pathogen, Mycobacterium ulcerans, the causal agent of Buruli ulcer disease. Mycolactone has pleiotropic effects on fundamental cellular processes (cell adhesion, cell death and inflammation). Various cellular targets of mycolactone have been identified and a literature survey revealed that most of these targets are membrane receptors residing in ordered plasma membrane nanodomains, within which their functionalities can be modulated...
January 10, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29214189/data-on-flow-cell-optimization-for-membrane-based-electrokinetic-energy-conversion
#2
David Nicolas Østedgaard-Munck, Jacopo Catalano, Mette Birch Kristensen, Anders Bentien
This article elaborates on the design and optimization of a specialized flow cell for the measurement of direct conversion of pressure into electrical energy (Electrokinetic Energy Conversion, EKEC) which has been presented in Østedgaard-Munck et al. (2017) [1]. Two main flow cell parameters have been monitored and optimized: A) the hydraulic pressure profile on each side of the membrane introduced by pumps recirculating the electrolyte solution through the flow fields and B) the electrical resistance between the current collectors across the combined flow cell...
December 2017: Data in Brief
https://www.readbyqxmd.com/read/29172443/membrane-crossing-and-membranotropic-activity-of-cell-penetrating-peptides-dangerous-liaisons
#3
Astrid Walrant, Sébastien Cardon, Fabienne Burlina, Sandrine Sagan
Living organisms have to maintain a stable balance in molecules and ions in the changing environment in which they are living, a process known as homeostasis. At the level of cells, the plasma membrane has a major role in homeostasis, since this hydrophobic film prevents passive diffusion of large and hydrophilic molecules between the extracellular and intracellular milieu. Living organisms have evolved with highly sophisticated transport systems to control exchanges across this barrier: import of nutrients and fuel essential for their survival; recognition of chemical or physical messengers allowing information interchanges with surrounding cells...
November 27, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29150176/studies-on-in-vitro-hypoglycemic-effects-of-root-bark-of-caesalpinia-bonducella
#4
F J Sayyed, G H Wadkar
OBJECTIVE: The present investigation was undertaken to assess the hypoglycemic potential of ethanolic (ECB) and aqueous extracts (ACB) of root bark of Caesalpinia bonducella using various in vitro techniques. METHOD: The ethanolic and aqueous extracts of root bark of C. bonducella were studied for their effects on glucose adsorption capacity, in vitro glucose diffusion, in-vitro amylolysis kinetics and glucose transport across membrane of yeast cells. RESULT: It was observed that the extracts under study adsorbed glucose and the adsorption of glucose increased remarkably with an increase in glucose concentration...
November 14, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/29103653/enhanced-lead-and-cadmium-removal-using-biochar-supported-hydrated-manganese-oxide-hmo-nanoparticles-behavior-and-mechanism
#5
Shunli Wan, Jiayu Wu, Shanshan Zhou, Rui Wang, Bin Gao, Feng He
Hydrated manganese oxide (HMO) nanoparticles were impregnated into a peanut shell-derived biochar (BC) to obtain a remarkable nanocomposite adsorbent, HMO-BC, which overcomes the technical barriers of singly applying either HMO or BC in practical heavy metal-containing wastewater treatment. HMO-BC can effectively sequestrate Pb(II) and Cd(II) in a wide pH range of 3-7 and exhibited more preferable sorption than bare BC in the presence of high-level competing cations. BC also significantly lowered the Mn leaching at acidic pH...
November 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29059551/treatment-of-methylene-blue-containing-wastewater-by-a-cost-effective-micro-scale-biochar-polysulfone-mixed-matrix-hollow-fiber-membrane-performance-and-mechanism-studies
#6
Jinsong He, Anan Cui, Shihuai Deng, J Paul Chen
Dye containing wastewater has increasingly become an important contamination due to operation of various industries such as textile industry. In this study, a micro-scale biochar particles/polysulfone mixed matrix hollow fiber membrane (MMM) was applied for the removal of methylene blue from water. The static and dynamic adsorption performance was investigated. We found that the MMM exhibited a high removal efficiency of methylene blue under a wide pH range of 4-10. The adsorption process on biochar and MMM obeyed the intraparticle surface diffusion model and Langmuir isotherm model...
September 28, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29051271/combined-measurement-of-carbon-monoxide-and-nitric-oxide-lung-transfer-does-not-improve-the-identification-of-pulmonary-hypertension-in-systemic-sclerosis
#7
Bruno Degano, Thibaud Soumagne, Thomas Delaye, Patrick Berger, Thierry Perez, Alicia Guillien, Jean-Luc Pellegrin, David Launay, Nadine Magy-Bertrand, Christian Agard, Kiet Phong Tiev, Thông Hua-Huy, Catherine Tardiff, Véronique Diaz, Arnaud Chambellan, Anh Tuan Dinh-Xuan
Screening is important to determine whether patients with systemic sclerosis (SSc) have pulmonary hypertension because earlier pulmonary hypertension treatment can improve survival in these patients. Although decreased transfer factor of the lung for carbon monoxide (TLCO) is currently considered the best pulmonary function test for screening for pulmonary hypertension in SSc, small series have suggested that partitioning TLCO into membrane conductance (diffusing capacity) for carbon monoxide (DMCO) and alveolar capillary blood volume (VC) through combined measurement of TLCO and transfer factor of the lung for nitric oxide (TLNO) is more effective to identify pulmonary hypertension in SSc patients compared with TLCO alone...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29039809/diffusive-and-metabolic-constraints-to-photosynthesis-in-quinoa-during-drought-and-salt-stress
#8
Dilek Killi, Matthew Haworth
Quinoa (Chenopodium quinoa Willd.) has been proposed as a hardy alternative to traditional grain crops in areas with warm-to-hot climates that are likely to experience increased drought and salt stress in the future. We characterised the diffusive and metabolic limitations to photosynthesis in quinoa exposed to drought and salt stress in isolation and combination. Drought-induced pronounced stomatal and mesophyll limitations to CO₂ transport, but quinoa retained photosynthetic capacity and photosystem II (PSII) performance...
October 17, 2017: Plants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29020065/gold-nanoparticles-stabilized-with-%C3%AE-cyclodextrin-2-amino-4-4-chlorophenyl-thiazole-complex-a-novel-system-for-drug-transport
#9
I Asela, M Noyong, U Simon, J Andrades-Lagos, J Campanini-Salinas, D Vásquez-Velásquez, M Kogan, N Yutronic, R Sierpe
While 2-amino-4-(4-chlorophenyl)thiazole (AT) drug and thiazole derivatives have several biological applications, these compounds present some drawbacks, such as low aqueous solubility and instability. A new complex of βCD-AT has been synthesized to increase AT solubility and has been used as a substrate for the deposit of solid-state AuNPs via magnetron sputtering, thus forming the βCD-AT-AuNPs ternary system, which is stable in solution. Complex formation has been confirmed through powder X-ray diffraction and 1D and 2D nuclear magnetic resonance...
2017: PloS One
https://www.readbyqxmd.com/read/28969687/metabolically-conditioned-media-derived-from-bone-marrow-stromal-cells-or-human-skin-fibroblasts-act-as-effective-chemoattractants-for-mesenchymal-stem-cells
#10
Anastasia Gabrielyan, Elena Neumann, Michael Gelinsky, Angela Rösen-Wolff
BACKGROUND: The main goal of bone tissue engineering has been the generation of healthy bone in order to replace affected tissue. Therefore, optimized biomaterials are needed which allow the survival and growth of mesenchymal stem cells. Until now the key challenge in the clinical application of cell-based tissue engineering bone implants was poor diffusion of oxygen into the tissue, making functional blood vessel networks a necessity. With their ability to evolve into different cell types, to expand extensively in vitro, and to release paracrine soluble factors, bone marrow stromal cells (BMSC) are highly attractive for tissue engineering...
September 29, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28940964/graphene-oxide-membranes-with-heterogeneous-nanodomains-for-efficient-co2-separations
#11
Shaofei Wang, Yu Xie, Guangwei He, Qingping Xin, Jinhui Zhang, Leixin Yang, Yifan Li, Hong Wu, Yuzhong Zhang, Michael D Guiver, Zhongyi Jiang
Achieving high membrane performance in terms of gas permeance and carbon dioxide selectivity is an important target in carbon capture. Aiming to manipulate the channel affinity towards CO2 to implement efficient separations, gas separation membranes containing CO2 -philic and non-CO2 -philic nanodomains in the interlayer channels of graphene oxide (GO) were formed by intercalating poly(ethylene glycol) diamines (PEGDA). PEGDA reacts with epoxy groups on the GO surface, constructing CO2 -philic nanodomains and rendering a high sorption capacity, whereas unreacted GO surfaces give non-CO2 -philic nanodomains, rendering low-friction diffusion...
September 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28920748/investigation-of-the-transport-and-absorption-of-angelica-sinensis-polysaccharide-through-gastrointestinal-tract-both-in-vitro-and-in-vivo
#12
Kaiping Wang, Fang Cheng, Xianglin Pan, Tao Zhou, Xiqiu Liu, Ziming Zheng, Li Luo, Yu Zhang
To investigate the absorption and delivery of ASP in gastrointestinal (GI) tract, cASP was successfully synthesized by chemically modifying with succinic anhydride and then conjugating with a near infrared fluorescent dye Cy5.5. Then, the capacity of oral absorption of cASP was evaluated. The results demonstrated that cASP had low toxicity and no disruption on the integrity of cell membrane. The endocytosis of cASP into the epithelial cells was time- and energy-dependent, which was mediated by macropinocytosis pathway and clathrin- and caveolae (or lipid raft)-related routes...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28913582/glyphosate-ab-sorption-by-shoots-and-rhizomes-of-native-versus-hybrid-cattail-typha
#13
Tianye Zheng, Nora B Sutton, Pim de Jager, Richard Grosshans, Sirajum Munira, Annemieke Farenhorst
Wetlands in the Prairie Pothole Region of North America are integrated with farmland and contain mixtures of herbicide contaminants. Passive nonfacilitated diffusion is how most herbicides can move across plant membranes, making this perhaps an important process by which herbicide contaminants are absorbed by wetland vegetation. Prairie wetlands are dominated by native cattail (Typha latifolia) and hybrid cattail (Typha x glauca). The objective of this batch equilibrium study was to compare glyphosate absorption by the shoots and rhizomes of native versus hybrid cattails...
November 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28847092/development-of-a-novel-biochar-psf-mixed-matrix-membrane-and-study-of-key-parameters-in-treatment-of-copper-and-lead-contaminated-water
#14
Jinsong He, Yihua Song, J Paul Chen
Mixed matrix membrane (MMM) has attracted increasing attentions in various applications, such as water treatment. In this study, an innovative biochar/polysulfone (PSF) mixed matrix hollow fiber membrane was fabricated by incorporating micro-sized biochar particles in the PSF matrix. It was demonstrated that the membrane was more hydrophilic than the pure PSF membrane. Higher water flux was obtained. The adsorption of copper and lead on the MMM increased as the pH was increased with the maximum adsorption capacity observed at pH > 4...
November 2017: Chemosphere
https://www.readbyqxmd.com/read/28821240/avbd1-nucleotide-polymorphisms-peptide-antimicrobial-activities-and-microbial-colonisation-of-the-broiler-chicken-gut
#15
Kevin Cadwell, Sherko S Niranji, Vanessa L Armstrong, Catherine A Mowbray, Richard Bailey, Kellie A Watson, Judith Hall
BACKGROUND: The importance of poultry as a global source of protein underpins the chicken genome and associated SNP data as key tools in selecting and breeding healthy robust birds with improved disease resistance. SNPs affecting host peptides involved in the innate defences tend to be rare, but three non-synonymous SNPs in the avian β-defensin (AvBD1) gene encoding the variant peptides NYH, SSY and NYY were identified that segregated specifically to three lines of commercial broiler chickens Line X (LX), Line Y(LY) and Line Z...
August 18, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28797964/enhancing-biodegradation-of-c16-alkyl-quaternary-ammonium-compounds-using-an-oxygen-based-membrane-biofilm-reactor
#16
YenJung Sean Lai, Aura Ontiveros-Valencia, Zehra Esra Ilhan, Yun Zhou, Evelyn Miranda, Juan Maldonado, Rosa Krajmalnik-Brown, Bruce E Rittmann
Quaternary ammonium compounds (QACs) (e.g., hexadecyltrimethyl-ammonium bromide, CTAB) are emerging contaminants with widespread use as surfactants and disinfectants. Because the initial step of QAC biodegradation is mono-oxygenation, QAC degraders require O2, but normal aeration leads to serious foaming. Here, we developed and tested an oxygen-based membrane biofilm reactor (O2-MBfR) that delivers O2 by diffusion through the walls of hollow-membranes to a biofilm accumulating on the outer surface of membranes...
October 15, 2017: Water Research
https://www.readbyqxmd.com/read/28793192/sulfonic-membrane-sorption-and-permeation-properties-complementary-approaches-to-select-a-membrane-for-pervaporation
#17
C Chappey, K Fatyeyeva, E Rynkowska, W Kujawski, L Karpenko-Jereb, A-M Kelterer, S Marais
In this contribution, the physical and chemical properties of the dense sulfonic membrane IonClad R4010 in the lithium form were studied to evaluate its potential application in pervaporation. To develop new membrane materials, it is necessary to know the influence of the membrane structure on the membrane equilibrium and transport properties. For this purpose, the sorption and permeation measurements of water and methanol in the liquid and vapor states were performed and correlated to the ion pairs/solvent interactions analyzed by the infrared spectroscopy...
August 29, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28782664/intra-session-and-inter-session-variability-of-nitric-oxide-pulmonary-diffusing-capacity-in-adults-with-cystic-fibrosis
#18
Thomas Radtke, Christian Benden, Marion Maggi-Beba, Susi Kriemler, Ivo van der Lee, Holger Dressel
We evaluated the intra-session and inter-session variability of the diffusing capacity of nitric oxide (DLNO), carbon monoxide (DLCO), alveolar-capillary membrane diffusing capacity for carbon monoxide (DMCO) and pulmonary capillary blood volume (Vc) in patients with cystic fibrosis (CF). Patients performed single-breath diffusing capacity measurements during all of 3 consecutive study visits. Precision of gas diffusing parameters was quantified by within-subject standard deviation (SDws) and coefficient of variation (CV)...
December 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28772627/bppo-based-anion-exchange-membranes-for-acid-recovery-via-diffusion-dialysis
#19
Muhammad Imran Khan, Rafael Luque, Pepijn Prinsen, Aziz Ur Rehman, Saima Anjum, Muhammad Nawaz, Aqeela Shaheen, Shagufta Zafar, Mujahid Mustaqeem
To reduce the environmental impact of acids present in various industrial wastes, improved and robust anion exchange membranes (AEMs) are highly desired. Moreover, they should exhibit high retention of salts, fast acid permeation and they should be able to operate with low energy input. In this work, AEMs are prepared using a facile solution-casting from brominated poly-(2,6-dimethyl-1,4-phenylene oxide) (BPPO) and increasing amounts of 2-phenylimidazole (PI). Neither quaternary ammonium salts, nor ionic liquids and silica-containing compounds are involved in the synthesis...
March 7, 2017: Materials
https://www.readbyqxmd.com/read/28769101/allostimulatory-capacity-of-conditionally-immortalized-proximal-tubule-cell-lines-for-bioartificial-kidney-application
#20
Milos Mihajlovic, Lambertus P van den Heuvel, Joost G Hoenderop, Jitske Jansen, Martijn J Wilmer, Annemarie J F Westheim, Wil A Allebes, Dimitrios Stamatialis, Luuk B Hilbrands, Rosalinde Masereeuw
Novel renal replacement therapies, such as a bioartificial kidney (BAK), are needed to improve current hemodialysis treatment of end-stage renal disease (ESRD) patients. As BAK applications may reveal safety concerns, we assessed the alloimmunization and related safety aspects of readily available conditionally immortalized human proximal tubule epithelial cell (ciPTEC) lines to be used in BAK. Two ciPTEC lines, originally derived from urine and kidney tissue, were characterized for the expression and secretion of relevant molecules involved in alloimmunization and inflammatory responses, such as HLA class-I, HLA-DR, CD40, CD80, CD86, as wells as soluble HLA class I and proinflammatory cytokines (IL-6, IL-8 and TNF-α)...
August 2, 2017: Scientific Reports
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