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Qi Tang, Yan Jiang, Yali Xu, Hongmei Xia
PURPOSE: This study aimed to assess the early changes of left ventricular (LV) and right ventricular (RV) mechanics associated with anthracycline treatment for breast cancer and to determine whether two-dimensional speckle tracking echocardiography (2D-STE) analysis could predict chemotherapy-induced cardiotoxicity. BACKGROUND: Anthracycline generates progressive LV dysfunction associated with a poor prognosis. Early detection of minor change of myocardial mechanics is thus important...
December 2, 2016: Journal of Clinical Ultrasound: JCU
Rogério Teixeira, Ricardo Monteiro, Paulo Dinis, Maria José Santos, Ana Botelho, Nuno Quintal, Nuno Cardim, Lino Gonçalves
Vascular mechanics assessed with two-dimensional speckle tracking echocardiography (2D-STE) could be used as a new imaging surrogate of vascular stiffening. The CHA2DS2-VASc score is considered accurate as an estimate of stroke risk in non-valvular AF, although many potential stroke risk factors have not been included in this scoring method. The purpose of this research is to study the feasibility of evaluating vascular mechanics at the descending aorta in non-valvular AF patients using transesophageal 2D-STE and to analyze the association between descending aortic mechanics and stroke...
November 24, 2016: International Journal of Cardiovascular Imaging
Timur Mese, Baris Guven, Murat Muhtar Yilmazer, Mustafa Demirol, Şenay Çoban, Cem Karadeniz
Exercise stress echocardiography is rarely used in the follow-up of children with congenital heart disease following surgical repair. There are no data on global longitudinal strain (GLS) and global circumferential strain (GCS) during exercise in adolescents with repaired tetralogy of Fallot (TOF). The purpose of this prospective study was to investigate GLS and GCS using speckle tracking two-dimensional echocardiography (2D-STE) at rest and during exercise in adolescents with repaired TOF. Twenty patients with repaired TOF and 20 controls were included...
November 23, 2016: Pediatric Cardiology
Juan Cong, Zhibin Wang, Hong Jin, Wugang Wang, Kun Gong, Yuanyuan Meng, Yong Lee
BACKGROUND: The myocardial wall of the left ventricle is a complex, multilayered structure and is not homogenous. The aim of this study was to determine longitudinal strain (LS) in the three myocardial layers in normal pregnant women according to gestation proceedings. METHODS: The advanced two-dimensional speckle tracking echocardiography (2D STE) was performed on 62 women during each pregnancy trimester and 6 to 9 weeks after delivery, while 30 age-matched, healthy, nonpregnant women served as controls...
November 10, 2016: Cardiovascular Ultrasound
Kuniaki Hirose, Masao Daimon, Sakiko Miyazaki, Shuo-Ju Chiang, Ryoko Morimoto-Ichikawa, Masaki Maruyama, Takayuki Kawata, Hirotoshi Ohmura, Hiroyuki Daida
BACKGROUND: Although a cardioprotective effect of estrogen has been suggested by experimental studies, clinical data on the influence of estrogen on left ventricular (LV) diastolic function are sparse. The LV untwisting rate obtained by 2D speckle tracking echocardiography (2D-STE) is correlated with the time constant of LV pressure decay (tau), and this correlation is independent of left atrial pressure. Therefore, we used conventional Doppler echocardiography and 2D-STE to investigate changes in LV diastolic function during a single menstrual cycle in premenopausal women...
October 22, 2016: Journal of Cardiology
Bernd Hewing, Anna Maria Dehn, Oliver Staeck, Fabian Knebel, Sebastian Spethmann, Karl Stangl, Gert Baumann, Henryk Dreger, Klemens Budde, Fabian Halleck
BACKGROUND/AIMS: Cardiac changes observed in chronic kidney disease patients are of multifactorial origin including chronic uremia, hemodynamics or inflammation. Restoration of renal function by kidney transplantation (KTX) may reverse cardiac changes. Novel echocardiographic methods such as speckle tracking echocardiography (STE) allow early and sensitive detection of subtle changes of cardiac parameters. We evaluated changes of cardiac structure and function after KTX by advanced echocardiographic modalities...
2016: Kidney & Blood Pressure Research
Aroditis Konstantinos, Pikilidou Maria, Vourvouri Eleni, Hadjistavri Lina, Zebekakis Pantelis, Yovos John, Efthimiadis George, Karvounis Haralambos
Overproduction of thyroid hormones leads to structural as well as functional cardiac changes. Conventional echocardiography but also recently developed sophisticated two-dimensional echocardiography speckle (2D-STE) tracking allow elaborate evaluation of these changes. Our purpose was to investigate the effects of thyroid hormones overproduction on the heart in patients with Graves' disease and changes that occur after 6 months thyrostatic therapy. We conducted a prospective, case-control study of 6 months duration...
September 28, 2016: International Journal of Cardiovascular Imaging
Sergio Barros-Gomes, Brittney Williams, Lara F Nhola, Martha Grogan, Joseph F Maalouf, Angela Dispenzieri, Patricia A Pellikka, Hector R Villarraga
OBJECTIVES: This study evaluated whether 2-dimensional speckle-tracking echocardiography (2D-STE) has incremental value for prognosis over traditional clinical, echocardiographic, and serological markers-with main focus on the current prognostic staging system-in light-chain (AL) amyloidosis patients with preserved left ventricular ejection fraction. BACKGROUND: Cardiac amyloidosis (CA) is the major determinant of outcome in AL amyloidosis. The current prognostic staging system is based primarily on serum levels of cardiac troponin T (cTnT), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and free light chain differential (FLC-diff)...
September 8, 2016: JACC. Cardiovascular Imaging
Sung-Hee Shin, Young Ju Suh, Yong-Soo Baek, Man-Jong Lee, Sang-Don Park, Sung-Woo Kwon, Seong-Ill Woo, Dae-Hyeok Kim, Keum-Soo Park, Jun Kwan
BACKGROUND: Three-dimensional (3D) speckle tracking echocardiography (STE) has been developed to overcome the limitations of two-dimensional (2D) STE and has been applied in the several clinical settings. However, no data exist about the prognostic value of 3DSTE-based strain on clinical outcome after myocardial infarction (MI). This study was designed to investigate the prognostic value of area strain (AS) by 3D speckle tracking in predicting clinical outcome after acute MI. METHODS: We assessed 96 patients (62±14 years, 72% male) with acute MI and who had undergone a coronary angiography...
August 25, 2016: Echocardiography
Jiaqi Shen, Qiao Zhou, Yue Liu, Runlan Luo, Bijun Tan, Guangsen Li
BACKGROUND: Iron-deficiency anemia (IDA) is a global health problem and a common medical condition that can be seen in everyday clinical practice. And two-dimensional speckle tracking echocardiography (2D-STE) has been reported very useful in evaluating left atrial (LA) function, as well as left ventricular (LV) function. The aim of our study is to evaluate the LA function in patients with IDA by 2D-STE. METHODS: 65 patients with IDA were selected. This group of patients was then divided into two groups according to the degree of hemoglobin: group B (Hb > 90 g/L) and group C (Hb60 ~ 90 g/L)...
August 23, 2016: Cardiovascular Ultrasound
Flavio D'Ascenzi, Marco Solari, Michele Mazzolai, Matteo Cameli, Matteo Lisi, Valentina Andrei, Marta Focardi, Marco Bonifazi, Sergio Mondillo
Two-dimensional (2D) speckle-tracking echocardiography (STE) has clarified functional adaptations accompanying the morphological features of 'athlete's heart'. However, 2D STE has some limitations, potentially overcome by three-dimensional (3D) STE. Unfortunately, discrepancies between 2D- and 3D STE have been described. We therefore sought to evaluate whether dimensional and functional differences exist between athletes and controls and whether 2D and 3D left ventricular (LV) strains differ in athletes. One hundred sixty-one individuals (91 athletes, 70 controls) were analysed...
August 13, 2016: International Journal of Cardiovascular Imaging
Chong Liu, Jing Li, Min Ren, Zhen-Zhen Wang, Zi-Yao Li, Fei Gao, Jia-Wei Tian
Two-dimensional speckle tracking echocardiography (2D-STE) multilayer analysis of myocardial deformation is a non-invasive method that enables discrimination of transmural differences owing to myocardial ischemia or necrosis. We wished to ascertain if multilayer longitudinal strains at rest are associated with significant (≥70 %) stenosis of the left anterior descending coronary artery (LAD) in patients with suspected non-ST-elevation acute coronary syndrome (NSTE-ACS). Our cohort comprised 113 consecutive patients with suspected NSTE-ACS and preserved ejection fraction (EF)...
August 13, 2016: International Journal of Cardiovascular Imaging
Sergio Barros-Gomes, Mackram F Eleid, Jordi S Dahl, Cristina Pislaru, Rick A Nishimura, Patricia A Pellikka, Sorin V Pislaru
AIMS: This study aimed (1) to evaluate the impact of preprocedural two-dimensional speckle-tracking echocardiography (2D-STE) on long-term outcome after successful percutaneous mitral balloon valvotomy (PMBV) in patients with mitral stenosis (MS) and (2) to determine whether 2D-STE detects underlying diastolic dysfunction as defined by invasive haemodynamic study. METHODS AND RESULTS: Sixty-four consecutive MS patients with preserved left ventricular ejection fraction (LVEF ≥50%) and who underwent successfully PMBV were studied...
August 7, 2016: European Heart Journal Cardiovascular Imaging
T Kivrak, M Sunbul, A Cincin, T Kani, E Durmus, M Banzragch, M Bozbay, Y Aydin, N Imeryuz, I Sari, H Akin, Y Basaran
OBJECTIVE: Crohn's disease (CD) is a chronic inflammatory bowel disease that can affect the entire gastrointestinal tract. Cardiac involvement is considered very rare. Pericarditis, myocarditis, endocarditis, cardiomyopathy and complete heart block are some of the cardiac extraintestinal manifestations of CD. The aim of this study was to explore the left ventricular (LV) functions with two-dimensional (2D) speckle tracking echocardiography (STE) in patients with CD with normal cardiac functions...
July 2016: European Review for Medical and Pharmacological Sciences
Prasad Gunasekaran, Sidakpal Panaich, Alexandros Briasoulis, Shaun Cardozo, Luis Afonso
Subclinical left ventricular (LV) dysfunction refers to subtle abnormalities in the LV function that typically precede a reduction in the left ventricular ejection fraction (LVEF). The assessment of myocardial function using LVEF, a radial metric of function, is subject to load dependence, intra-observer and inter-observer variability. Reductions in LVEF typically manifest late in the disease process thus compromising the ability to intervene before irreversible impairment of systolic performance sets in. 2-Dimensional speckle tracking echocardiography (2D-STE), a novel strain imaging modality has shown promise as a sensitive indicator of myocardial contractility...
July 11, 2016: Current Cardiology Reviews
Amal Mohamed Ayoub, Viola William Keddeas, Yasmin Abdelrazek Ali, Reham Atef El Okl
BACKGROUND: Early detection of subclinical left ventricular (LV) systolic dysfunction in hypertensive patients is important for the prevention of progression of hypertensive heart disease. METHODS: We studied 60 hypertensive patients (age ranged from 21 to 49 years, the duration of hypertension ranged from 1 to 18 years) and 30 healthy controls, all had preserved left ventricular ejection fraction (LVEF), detected by two-dimensional speckle tracking echocardiography (2D-STE)...
2016: Clinical Medicine Insights. Cardiology
S M Aung, A Güler, Y Güler, A Huraibat, C Y Karabay, I Akdemir
BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) is a syndrome in which patients have symptoms and signs of heart failure but preserved ejection fraction. Left atrial (LA) volume and function are known to be impaired in these patients. Two-dimensional speckle-tracking echocardiography (2D-STE) has recently enabled the quantification of LA deformation dynamics. In this study, we evaluated the use of 2D-STE for the diagnosis of HFpEF. PATIENTS AND METHODS: The study included 83 patients with suspected HFpEF...
June 28, 2016: Herz
Nadia Benyounes, Sylvie Lang, Olivier Gout, Yann Ancédy, Arnaud Etienney, Ariel Cohen
BACKGROUND: Transthoracic echocardiography is the most commonly used tool for the detection of left ventricular wall motion (LVWM) abnormalities using "naked eye evaluation". This subjective and operator-dependent technique requires a high level of clinical training and experience. Two-dimensional speckle-tracking echocardiography (2D-STE), which is less operator-dependent, has been proposed for this purpose. However, the role of on-line segmental longitudinal peak systolic strain (LPSS) values in the prediction of LVWM has not been fully evaluated...
June 22, 2016: Archives of Cardiovascular Diseases
Regayip Zehir, Can Yucel Karabay, Gonenc Kocabay, Mehmet Remzi Erdem, Muhsin Balaban, Cevat Kirma
BACKGROUND: Vasculogenic erectile dysfunction is a harbinger of vascular disease. Comprehensive cardiac workup is accepted to be beneficial in men with this condition, especially those with otherwise unrecognized cardiovascular disease. We aimed to evaluate the role of two-dimensional speckle-tracking echocardiography (2D-STE) for noninvasive evaluation in patients with documented arteriogenic erectile dysfunction. METHODS: 64 consecutive men with Doppler proven erectile dysfunction of more than 3 months of duration were recruited...
August 2016: Journal of Sexual Medicine
Aparna Kulkarni, Ling Li, Mary Craft, Mitali Nanda, Jose Miguel Mateo Lorenzo, David Danford, Shelby Kutty
OBJECTIVES: Experimental evidence suggests that changes in fetal myocardium occur from intrauterine effects of maternal diabetes mellitus and obesity. The aim of this study was to assess fetal cardiac function using two-dimensional speckle-tracking echocardiography (2D-STE) to determine the effects of maternal diabetes and obesity on the fetal myocardium. METHODS: Comparative cross-sectional evaluation of myocardial function using two-dimensional speckle-tracking echocardiography (2D-STE) in fetuses of mothers with diabetes mellitus (FDM), fetuses of mothers with obesity (FO) and normal fetal controls (FC) was performed at two centers...
May 24, 2016: Ultrasound in Obstetrics & Gynecology
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