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https://www.readbyqxmd.com/read/29777975/geriatric-analysis-from-prodige-20-randomized-phase-ii-trial-evaluating-bevacizumab-chemotherapy-versus-chemotherapy-alone-in-older-patients-with-untreated-metastatic-colorectal-cancer
#1
T Aparicio, O Bouché, E Francois, F Retornaz, E Barbier, J Taieb, S Kirscher, P-L Etienne, R Faroux, F Khemissa Akouz, F El Hajbi, C Locher, Y Rinaldi, T Lecomte, S Lavau-Denes, M Baconnier, A Oden-Gangloff, D Genet, L Bedenne, E Paillaud
BACKGROUND: Older patients have frailty characteristics that impair the transposition of treatment results found in younger patients. Predictive factors are needed to help with treatment choices for older patients. The PRODIGE 20 study is a randomized phase II study that evaluated chemotherapy associated with bevacizumab (BEV) or not (CT) in patients aged 75 years or older. PATIENTS AND METHODS: Patients underwent a geriatric assessment at randomization and at each evaluation...
May 16, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29777304/no-improvement-in-vitamin-d-status-in-german-infants-and-adolescents-between-2009-and-2014-despite-public-recommendations-to-increase-vitamin-d-intake-in-2012
#2
Clemens Kunz, Jürgen Hower, Anette Knoll, Kristin L Ritzenthaler, Thomas Lamberti
PURPOSE: Vitamin D is a key component for the growth and development of children and adolescents, influencing a multitude of functions. Worldwide epidemiological studies have shown that minimum vitamin D blood levels of ≥ 20.0 ng/ml, often defined as vitamin D sufficiency by international and national nutrition and pediatric organizations, are often not met in practice. In 2012 the D-A-CH (Germany, Austria, Switzerland) nutrition societies increased their vitamin D intake recommendations fourfold from 200 IU (5 µg) to 800 IU (20 µg) per day...
May 18, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29777245/growth-assessment-and-monitoring-during-childhood
#3
Fabian Yap, Yung Seng Lee, Marion Margaret Hy Aw
Growth is an indicator of the health and nutritional status of infants and children. Health organisations and professionals worldwide advocate monitoring the growth of children with the primary aim of identifying and preventing malnutrition and/or obesity. Growth monitoring should be part of every health care consultation for children. However, physicians during health care consultations are often so busy addressing acute health issues, that they miss the opportunity to monitor the child's growth and provide anticipatory guidance...
April 2018: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/29776365/nutrient-intake-disparities-in-the-us-modeling-the-effect-of-food-substitutions
#4
Zach Conrad, LuAnn K Johnson, James N Roemmich, WenYen Juan, Lisa Jahns
BACKGROUND: Diet quality among federal food assistance program participants remains low, and little research has assessed the diet quality of food insecure non-participants. Further research is needed to assess the extent to which food substitutions can improve the nutritional status of these vulnerable populations. Substituting egg dishes for other commonly consumed dishes at certain eating occasions may be an effective strategy for improving the daily nutrient intake among these groups...
May 17, 2018: Nutrition Journal
https://www.readbyqxmd.com/read/29775433/asian-american-mothers-demographic-characteristics-by-maternal-place-of-birth-and-asian-subgroup-2016
#5
Anne K Driscoll
This report describes women of Asian descent who gave birth in the United States in 2016. The 2016 vital statistics natality file was used to compare demographic characteristics of non-Hispanic Asian mothers across six Asian subgroups-Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese-both overall and by whether they were U.S.-born or born outside the United States. In addition, non-Hispanic Asian mothers were compared with the overall U.S. population of mothers. Overall, 6.4% of U.S. births in 2016 were to non-Hispanic Asian women...
April 2018: National Vital Statistics Reports
https://www.readbyqxmd.com/read/29775238/comparison-of-creatinine-index-and-geriatric-nutritional-risk-index-for-nutritional-evaluation-of-patients-with-hemodialysis
#6
Wonsun Hwang, Mi Sook Cho, Ji Eun Oh, Ji Hyun Lee, Jong Cheol Jeong, Gyu-Tae Shin, Heungsoo Kim, Inwhee Park
INTRODUCTION: Malnutrition is prevalent in hemodialysis (HD) patients, and the risk of mortality is strongly correlated with malnutrition. Current methods of nutritional evaluation are mostly subjective, time-consuming, and cumbersome. Creatinine index (CI) and geriatric nutritional risk index (GNRI) are very simple and objective methods to assess the nutritional status of HD patients. The present study compares the performance of CI and GNRI as nutritional risk assessment tools. METHODS: Eighty-eight patients with end-stage renal disease on HD were recruited from a single tertiary center...
May 18, 2018: Hemodialysis International
https://www.readbyqxmd.com/read/29775187/body-mass-index-is-associated-with-all-cause-mortality-after-tha-and-tka
#7
Michelle M Dowsey, Peter F M Choong, Elizabeth W Paxton, Tim Spelman, Robert S Namba, Maria C S Inacio
BACKGROUND: Both obesity and underweight are associated with a higher risk of mortality in adulthood, but the association between mortality after arthroplasty and extreme ranges of body mass index (BMI) have not been evaluated beyond the first year. QUESTIONS/PURPOSES: The purpose of this study was to investigate the association between BMI and all-cause mortality after TKA and THA. METHODS: Data from two arthroplasty registries, the St Vincent's Melbourne Arthroplasty (SMART) Registry from Australia and the Kaiser Permanente Total Joint Replacement Registry (KPTJRR) from the United States, were used to identify patients aged ≥ 18 years undergoing elective TKAs and THAs between January 1, 2002, and December 31, 2013...
June 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29774828/bilberry-pomace-in-rabbit-nutrition-effects-on-growth-performance-apparent-digestibility-caecal-traits-bacterial-community-and-antioxidant-status
#8
S Dabbou, I Ferrocino, A Kovitvadhi, S Bergagna, D Dezzuto, A Schiavone, L Cocolin, F Gai, V Santoro, L Gasco
Agricultural by-products could be used as alternative raw materials in rabbit nutrition as they have been found to be highly nutritious and low cost feeding sources. The aim of this study was to estimate the nutritive value and potential use of bilberry pomace (BP) for growing rabbits. A total of 144 Grimaud rabbits (35 days old) were allotted to four groups and fed with a diet containing increasing level of BP: BP0 (basal diet), BP5, BP10 and BP15 containing 0, 50, 100 and 150 g/kg respectively. Growth trial lasted 48 days; apparent digestibility was evaluated, starting at 46 days of age, over 4 consecutive days...
May 18, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29773950/could-autism-be-associated-with-nutritional-status-in-the-palestinian-population-the-outcomes-of-the-palestinian-micronutrient-survey
#9
Mohammad Altamimi
Background: Autism spectrum disorder is a neurodevelopmental disorder. It is believed that the cause of autism is multifactorial, where genetic predispositions interact with environmental factors. In this context, micronutrients play a crucial role. Objective: To present evidence on current micronutrient status in Palestine and highlight its possible role in increasing problems of neurodevelopment disorders in general and autism in particular. Method: Analytical review of results...
2018: Nutrition and Metabolic Insights
https://www.readbyqxmd.com/read/29773940/effects-of-social-support-network-size-on-mortality-risk-considerations-by-diabetes-status
#10
Paul D Loprinzi, M Allison Ford
Objective: Previous work demonstrates that social support is inversely associated with mortality risk. Less research, however, has examined the effects of the size of the social support network on mortality risk among those with and without diabetes, which was the purpose of this study. Methods: Data from the 1999-2008 National Health and Nutrition Examination Survey were used, with participants followed through 2011. This study included 1,412 older adults (≥60 years of age) with diabetes and 5,872 older adults without diabetes...
May 2018: Diabetes Spectrum: a Publication of the American Diabetes Association
https://www.readbyqxmd.com/read/29772068/risk-factors-associated-with-preterm-delivery-and-low-delivery-weight-among-hiv-exposed-neonates-in-china
#11
Liming Wang, Hongxin Zhao, Weiping Cai, Jie Tao, Qingxia Zhao, Lijun Sun, Qingbo Fan, Athena P Kourtis, Colin Shepard, Fujie Zhang
OBJECTIVE: To examine the relationship between combination antiretroviral therapy (cART) and preterm delivery (PTD) or low delivery weight among pregnant Chinese women with HIV. METHODS: The present retrospective cross-sectional medical chart review enrolled pregnant women with HIV who delivered at five tertiary hospitals in China between January 1, 2009, and December 31, 2014. Generalized linear mixed modeling was used to explore PTD (<37 weeks of pregnancy) and low delivery weight (<2500 g) risk factors...
May 17, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29771910/the-influence-of-crop-production-and-socioeconomic-factors-on-seasonal-household-dietary-diversity-in-burkina-faso
#12
Jérôme W Somé, Andrew D Jones
Households in low-income settings are vulnerable to seasonal changes in dietary diversity because of fluctuations in food availability and access. We assessed seasonal differences in household dietary diversity in Burkina Faso, and determined the extent to which household socioeconomic status and crop production diversity modify changes in dietary diversity across seasons, using data from the nationally representative 2014 Burkina Faso Continuous Multisectoral Survey (EMC). A household dietary diversity score based on nine food groups was created from household food consumption data collected during four rounds of the 2014 EMC...
2018: PloS One
https://www.readbyqxmd.com/read/29771182/ciliogenesis-is-reciprocally-regulated-by-ppara-and-nr1h4-fxr-through-controlling-autophagy-in-vitro-and-in-vivo
#13
Zhi-Qiang Liu, Joon No Lee, Myeongjoo Son, Jae-Young Lim, Raghbendra Kumar Dutta, Yunash Maharjan, SeongAe Kwak, Goo Taeg Oh, Kyunghee Byun, Seong-Kyu Choe, Raekil Park
The primary cilia are evolutionarily conserved microtubule-based cellular organelles that perceive metabolic status and thus link the sensory system to cellular signaling pathways. Therefore, ciliogenesis is thought to be tightly linked to autophagy, which is also regulated by nutrient-sensing transcription factors, such as PPARA (peroxisome proliferator activated receptor alpha) and NR1H4/FXR (nuclear receptor subfamily 1, group H, member 4). However, the relationship between these factors and ciliogenesis has not been clearly demonstrated...
May 17, 2018: Autophagy
https://www.readbyqxmd.com/read/29771099/-screening-for-undernutrition-among-older-adults-receiving-home-care-an-estimation-of-the-diagnostic-accuracy-of-indicators-available-in-the-resident-assessment-instrument-home-care-adapted-for-switzerland
#14
Catherine Busnel, Catherine Ludwig
INTRODUCTION: in homecare practice, nurses are central actors for the screening of individuals at risks of undernutrition. CONTEXT: in Switzerland, homecare nurses estimate the nutritional status of care recipients by means of a standardized geriatric assessment done with the RAI-HC. AIMS: The aim of the study is to estimate the diagnostic accuracy of the « nutritional status » score, the body mass index and the weight loss documented from the RAI-HC...
March 2018: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/29770960/interventions-for-increasing-fruit-and-vegetable-consumption-in-children-aged-five-years-and-under
#15
REVIEW
Rebecca K Hodder, Kate M O'Brien, Fiona G Stacey, Rebecca J Wyse, Tara Clinton-McHarg, Flora Tzelepis, Erica L James, Kate M Bartlem, Nicole K Nathan, Rachel Sutherland, Emma Robson, Sze Lin Yoong, Luke Wolfenden
BACKGROUND: Insufficient consumption of fruits and vegetables in childhood increases the risk of future non-communicable diseases, including cardiovascular disease. Interventions to increase consumption of fruit and vegetables, such as those focused on specific child-feeding strategies and parent nutrition education interventions in early childhood may therefore be an effective strategy in reducing this disease burden. OBJECTIVES: To assess the effectiveness, cost effectiveness and associated adverse events of interventions designed to increase the consumption of fruit, vegetables or both amongst children aged five years and under...
May 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29770842/clinical-features-and-practice-patterns-of-gastroschisis-a-retrospective-analysis-using-a-japanese-national-inpatient-database
#16
Michimasa Fujiogi, Nobuaki Michihata, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga, Jun Fujishiro
PURPOSE: The number of infants with gastroschisis is increasing worldwide, but advances in neonatal intensive care and parenteral nutrition have reduced gastroschisis mortality. Recent clinical data on gastroschisis are often from Western nations. This study aimed to examine clinical features and practice patterns of gastroschisis in Japan. METHODS: We examined treatment options, outcomes, and discharge status among inpatients with simple gastroschisis (SG) and complex gastroschisis (CG), 2010-2016, using a national inpatient database in Japan...
May 16, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29770565/a-review-of-child-stunting-determinants-in-indonesia
#17
REVIEW
Ty Beal, Alison Tumilowicz, Aang Sutrisna, Doddy Izwardy, Lynnette M Neufeld
Child stunting reduction is the first of 6 goals in the Global Nutrition Targets for 2025 and a key indicator in the second Sustainable Development Goal of Zero Hunger. The prevalence of child stunting in Indonesia has remained high over the past decade, and at the national level is approximately 37%. It is unclear whether current approaches to reduce child stunting align with the scientific evidence in Indonesia. We use the World Health Organization conceptual framework on child stunting to review the available literature and identify what has been studied and can be concluded about the determinants of child stunting in Indonesia and where data gaps remain...
May 17, 2018: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29770549/importance-of-frailty-evaluation-in-the-prediction-of-the-prognosis-of-patients-with-chronic-subdural-hematoma
#18
Kiyoharu Shimizu, Takashi Sadatomo, Takeshi Hara, Shumpei Onishi, Kiyoshi Yuki, Kaoru Kurisu
AIM: The present study aimed to clarify the relationship between frailty and prognosis of patients with chronic subdural hematoma. METHODS: This retrospective study involved 211 patients aged ≥65 years with chronic subdural hematoma, who underwent surgery at Higashihiroshima Medical Center, Hiroshima, Japan, between July 2011 and May 2017. The study outcome was the patient's modified Rankin Scale score at 3 months after surgery. A logistic regression analysis was carried out to analyze factors that influenced the outcome...
May 17, 2018: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29769574/honey-bees-consider-larval-nutritional-status-rather-than-genetic-relatedness-when-selecting-larvae-for-emergency-queen-rearing
#19
Ramesh R Sagili, Bradley N Metz, Hannah M Lucas, Priyadarshini Chakrabarti, Carolyn R Breece
In honey bees and many other social insects, production of queens is a vital task, as colony fitness is dependent on queens. The factors considered by honey bee workers in selecting larvae to rear new queens during emergency queen rearing are poorly understood. Identifying these parameters is critical, both in an evolutionary and apicultural context. As female caste development in honey bees is dependent on larval diet (i.e. nutrition), we hypothesized that larval nutritional state is meticulously assessed and used by workers in selection of larvae for queen rearing...
May 16, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29769085/contemporary-enteral-and-parenteral-nutrition-before-surgery-for-gastrointestinal-cancers-a-literature-review
#20
REVIEW
Michal Jankowski, Manuela Las-Jankowska, Massaoud Sousak, Wojciech Zegarski
BACKGROUND: Gastrointestinal cancers are among the most recognised oncological diseases in well-developed countries. Tumours located in the digestive tract may cause the fast occurrence of malnutrition. MAIN TEXT: The perioperative period is a special time for systemic metabolism. Thanks to published guidelines, early universal control nutritional status before treatment, patients may have a chance to get suitable nutritional intervention. Although the first line of the intervention-nutritional consultation as well as the fortification of a diet and oral nutritional support (ONS)-is not debatable, in a case of inability of undergoing an oral feeding, the choice of the way of administration in patients before a surgery may represent a serious clinical obstacle...
May 16, 2018: World Journal of Surgical Oncology
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