Yangyang Zhang, Weicong Zhong, Wenting Liu, Xiaohua Wang, Gan Lin, Jiawen Lin, Junxuan Fang, Xiangyu Mou, Shan Jiang, Jiayuan Huang, Wenjing Zhao, Zhihua Zheng
INTRODUCTION: Chronic kidney disease (CKD) is worldwide healthcare burden with growing incidence and death rate. Emerging evidence demonstrated the compositional and functional differences of gut microbiota in patients with CKD. As such, gut microbial features can be developed as diagnostic biomarkers and potential therapeutic target for CKD. METHODS: To eliminate the outcome bias arising from factors such as geographical distribution, sequencing platform, and data analysis techniques, we conducted a comprehensive analysis of the microbial differences between patients with CKD and healthy individuals based on multiple samples worldwide...
2024: Frontiers in Cellular and Infection Microbiology