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traumatic spinal cord injury

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https://www.readbyqxmd.com/read/28081205/anxiety-and-depression-in-patients-with-traumatic-spinal-cord-injury-a-nationwide-population-based-cohort-study
#1
Sher-Wei Lim, Yow-Ling Shiue, Chung-Han Ho, Shou-Chun Yu, Pei-Hsin Kao, Jhi-Joung Wang, Jinn-Rung Kuo
BACKGROUND: Traumatic spinal cord injury (tSCI) may involve new-onset anxiety and depression post-discharge. However, long-term population-based studies have lacked access to follow-up conditions in terms of new-onset anxiety and depression. The objective of this study was to estimate the long-term risk of new-onset anxiety and depression post-discharge. METHODS: The Longitudinal Health Insurance Database 2000 (LHID2000) from Taiwan's National Health Insurance Research Database was used in this study...
2017: PloS One
https://www.readbyqxmd.com/read/28073201/azoospermic-patient-s-treatment-an-experience-of-a-pma-hospital-unit-and-role-of-ultrasonography
#2
Paolo Panella, Pietro Pepe, Placido Borzì, Maria Elena Vento, Michele Pennisi, Paolo Scollo
INTRODUCTION: Azoospermia causes about 10% of male infertility and the best therapeutic option is the retrieval of sperm from testis or epididymis. MATERIAL AND METHODS: From Juanary 2008 to June 2016, 92 men (median 36 years; range: 25-54 years) were submitted in 47 cases to TESE (testicular sperm extraction) and in 45 cases to PESA (percutaneous epididymal sperm aspiration) for secretory and obstructive azoospermia, respectively; moreover, all the patients previously underwent color Doppler ultrasound of the testis and transrectal ultrasound of the prostate...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28072744/posterior-arthrodesis-of-c1-c3-for-the-stabilization-of-multiple-unstable-upper-cervical-fractures-with-spinal-cord-compromise-a-case-report-and-literature-review
#3
Deting Xue, Qixin Chen, Gang Chen, Wenhai Zhuo, Fangcai Li
BACKGROUND: Multiple fractures of the atlas and axis are rare. The management of multiple fragment axis fractures and unstable atlas fractures is still challenging for the spinal surgeon. There are no published reports of similar fractures with 3-part fracture of axis associated with an unstable atlas fracture. CASE SUMMARY: We present a patient with concurrent axis and atlas fractures, which have not been reported. The patient suffered hyperextension injury with neck pain and numbness of the bilateral upper extremity associated with weakness after a 2-m fall...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28056628/optimizing-clinical-decision-making-in-acute-traumatic-spinal-cord-injury
#4
Michael Fehlings, Vanessa Noonan, Derek Atkins, Anthony Scott Burns, Christiana L Cheng, Anoushka Singh, Marcel F Dvorak
Please note that as this is the introductory article, there is no abstract for this article.
January 5, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28056008/traumatic-brain-and-spinal-cord-fatalities-among-high-school-and-college-football-players-united-states-2005-2014
#5
Kristen L Kucera, Rebecca K Yau, Johna Register-Mihalik, Stephen W Marshall, Leah C Thomas, Susanne Wolf, Robert C Cantu, Frederick O Mueller, Kevin M Guskiewicz
An estimated 1.1 million high school and 75,000 college athletes participate in tackle football annually in the United States. Football is a collision sport; traumatic injuries are frequent (1,2), and can be fatal (3). This report updates the incidence and characteristics of deaths caused by traumatic brain injury and spinal cord injury (4) in high school and college football and presents illustrative case descriptions. Information was analyzed from the National Center for Catastrophic Sport Injury Research (NCCSIR)...
January 6, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28053621/clinical-and-magnetic-resonance-imaging-features-of-compressive-cervical-myelopathy-with-traumatic-intervertebral-disc-herniation-in-cynomolgus-macaque-macaca-fascicularis
#6
Yun-Jung Choi, Hye-Jin Park, Chul-Ho Sohn, Kyeong Cheon Jung, Seong Hoe Park, Jae-Il Lee
Intervertebral disc herniation (IVDH) with nucleus pulposus extrusion, traumatic or not, is a devastating clinical condition accompanied by neurological problems. Here we report a cynomolgus macaque suffering from acute and progressive neurological dysfunction by a blunt trauma due to neck collar, an animal handling device. Tetraplegia, urinary incontinence, decreased proprioception, and imperception of pain were shown on physical and neurological examinations. MRI sagittal T2 weighted sequences revealed an extensive protrusion of disc material between C2 and C3 cervical vertebra, and this protrusion resulted in central stenosis of the spinal cord...
December 2016: Laboratory Animal Research
https://www.readbyqxmd.com/read/28052526/effectiveness-of-a-multi-layer-foam-dressing-in-preventing-sacral-pressure-ulcers-for-the-early-acute-care-of-patients-with-a-traumatic-spinal-cord-injury-comparison-with-the-use-of-a-gel-mattress
#7
Andréane Richard-Denis, Cynthia Thompson, Jean-Marc Mac-Thiong
Individuals with spinal cord injury are at risk of sacral pressure ulcers due to, among other reasons, prolonged immobilisation. The effectiveness of a multi-layer foam dressing installed pre-operatively in reducing sacral pressure ulcer occurrence in spinal cord injured patients was compared to that of using a gel mattress, and stratified analyses were performed on patients with complete tetraplegia and paraplegia. Socio-demographic and clinical data were collected from 315 patients admitted in a level-I trauma centre following a spinal cord injury between April 2010 and March 2016...
January 4, 2017: International Wound Journal
https://www.readbyqxmd.com/read/28045281/environmental-barriers-and-social-participation-in-individuals-with-spinal-cord-injury
#8
I-Hsuan Tsai, Daniel E Graves, Wenyaw Chan, Charles Darkoh, Meei-Shyuan Lee, Lisa A Pompeii
OBJECTIVE: The study aimed to examine the relationship between environmental barriers and social participation among individuals with spinal cord injury (SCI). METHOD: Individuals admitted to regional centers of the Model Spinal Cord Injury System in the United States due to traumatic SCI were interviewed and included in the National Spinal Cord Injury Database. This cross-sectional study applied a secondary analysis with a mixed effect model on the data from 3,162 individuals who received interviews from 2000 through 2005...
January 2, 2017: Rehabilitation Psychology
https://www.readbyqxmd.com/read/28032120/inhibition-of-poly-adp-ribosylation-fails-to-increase-axonal-regeneration-or-improve-functional-recovery-after-adult-mammalian-cns-injury
#9
Xingxing Wang, Yuichi Sekine, Alexandra B Byrne, William B J Cafferty, Marc Hammarlund, Stephen M Strittmatter
After traumatic damage of the brain or spinal cord, many surviving neurons are disconnected, and recovery of function is limited by poor axon regeneration. Recent data have suggested that poly ADP-ribosylation plays a role in limiting axonal regrowth such that inhibition of poly (ADP-ribose) polymerase (PARP) may have therapeutic efficacy for neurological recovery after trauma. Here, we tested systemic administration of the PARP inhibitor, veliparib, and showed effective suppression of PARylation in the mouse CNS...
November 2016: ENeuro
https://www.readbyqxmd.com/read/28026011/community-integration-outcomes-of-people-with-spinal-cord-injury-and-multiple-matched-controls-a-pilot-study
#10
Libby Callaway, Joanne Enticott, Louise Farnworth, Rachael McDonald, Christine Migliorini, Barry Willer
BACKGROUND/AIM: Australia's National Disability Insurance Scheme (NDIS) is designed to influence home, social and economic participation for Scheme participants. Given the major disability reform underway, this pilot study aimed to: (i) examine community integration outcomes of people with spinal cord injury (SCI); (ii) compare findings with multiple matched controls and (iii) consider findings within the context of Australia's NDIS. METHODS: Setting: Victoria, Australia...
December 27, 2016: Australian Occupational Therapy Journal
https://www.readbyqxmd.com/read/27998207/application-of-the-rat-grimace-scale-as-a-marker-of-supraspinal-pain-sensation-after-cervical-spinal-cord-injury
#11
Lonnie E Schneider, Kathryn Y Henley, Omari A Turner, Betty M Pat, Tracy L Niedzielko, Candace L Floyd
Experimental models of neuropathic pain (NP) typically rely on withdrawal responses to assess the presence of pain. Reflexive withdrawal responses to a stimulus are used to evaluate evoked pain and as such do not include the assessment of spontaneous NP nor evaluation of the affective and emotional consequences of pain in animal models. Additionally, withdrawal responses can be mediated by spinal cord reflexes and may not accurately indicate supraspinal pain sensation. This is especially true in models of traumatic spinal cord injury (SCI) wherein spastic syndrome, a motor disorder characterized by exaggeration of the stretch reflex that is secondary to hyperexcitability of the spinal reflex, can cause paroxysmal withdrawals not associated with NP sensation...
December 21, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27995938/a-radiographic-evaluation-of-facet-sagittal-angle-in-cervical-spinal-cord-injury-without-major-fracture-or-dislocation
#12
T Takao, K Kubota, T Maeda, S Okada, Y Morishita, E Mori, I Yugue, O Kawano, H Sakai, T Ueta, K Shiba
STUDY DESIGN: A retrospective radiographic study with a minimum 2-year follow-up. OBJECTIVE: To evaluate the relationships between the cervical articular facets' morphology and the incidence of traumatic cervical spinal cord injury (CSCI) without major fracture or dislocation. SETTING: Spinal Injuries Center, Japan. METHODS: This study included 113 patients with traumatic CSCI without major fracture or dislocation. Eighty-four healthy volunteers without neurological deficits or cervical cord pathology on magnetic resonance imaging (MRI) were defined as control subjects...
December 20, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27993583/depression-in-individuals-with-traumatic-and-non-traumatic-spinal-cord-injury-living-in-the-community
#13
Joan Saurí, Andrés Chamarro, Anna Gilabert, Mariona Gifre, Neus Rodriguez, Raquel Lopez-Blazquez, Lluïsa Curcoll, Jesús Benito-Penalva, Dolors Soler
OBJECTIVE: To assess depression in a sample of individuals with spinal cord injury (SCI) living in the community, and to determine the prevalence of probable major depression disorder (PMDD) amongst those for whom the injury is traumatic (T-SCI) and those for whom it is not (NT-SCI). DESIGN: Cross sectional. SETTING: Data were collected on individuals with SCI now living in the community, who completed a comprehensive follow-up assessment at the Guttmann Institute in Barcelona, Spain...
December 16, 2016: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/27990239/towards-parameters-and-protocols-to-recommend-fes-cycling-in-cases-of-paraplegia-a-preliminary-report
#14
Juliana Araujo Guimarães, Lucas Oliveira da Fonseca, Clarissa Cardoso Dos Santos-Couto-Paz, Antônio Padilha Lanari Bó, Charles Fattal, Christine Azevedo-Coste, Emerson Fachin-Martins
Functional Electrical Stimulation assisted cycling (FES-Cycling) is increasingly becoming an alternative option recommended to people with spinal cord injury struggling with paraplegia and interested in practicing sports. In order to propose preconditions to guide FES-Cycling recommendation, we aimed to investigate some features and their potential relationships with responsiveness to Neuromuscular Electrical Stimulation (NMES). Fourteen volunteers attended a public recruitment forum to be assessed about their responsiveness through the 16-sessions of NMES...
June 13, 2016: European Journal of Translational Myology
https://www.readbyqxmd.com/read/27981499/direct-conversion-of-somatic-cells-into-induced-neurons
#15
REVIEW
Na An, Huiming Xu, Wei-Qiang Gao, Hao Yang
The progressive loss and degeneration of neurons in the central nervous system (CNS), as a result of traumas or diseases including Alzheimer's, Parkinson's, Huntington's disease, stroke, and traumatic injury to the brain and spinal cord, can usually have devastating effects on quality of life. The current strategies available for treatments are described including drug delivery, surgery, electrical stimulation, and cell-based tissue engineering approaches. However, apart from cell-based therapy, other attempts are limited in improving clinical outcomes...
December 16, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27979630/cervical-spinal-cord-injury-without-computed-tomography-evidence-of-trauma-sciwoctet-in-adults-mri-prognostic-factors
#16
Rafael Martinez-Perez, Pablo M Munarriz, Igor Paredes, Javier Cotrina, Alfonso Lagares
BACKGROUND: and Purpose: Spinal Cord Injury without Computed Tomography evidence of Trauma (SCIWOCTET) is underreported in adults and is considered a subtype of SCI with relatively good outcomes. Despite this, few studies have been performed to determine specific imaging-related prognostic factors. Our objective is to describe the imaging characteristics of patients experiencing blunt cervical spine trauma with neurological deficits, but without radiological abnormalities and associated prognostic factors...
December 12, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27973679/effect-on-body-composition-and-bone-mineral-density-of-walking-with-a-robotic-exoskeleton-in-adults-with-chronic-spinal-cord-injury
#17
Antony D Karelis, Lívia Pinheiro Carvalho, Manuel Jose Castillo, Dany H Gagnon, Mylène Aubertin-Leheudre
OBJECTIVE: To examine the effect on body composition and bone mineral density of locomotor training using a robotic exoskeleton in individuals with spinal cord injury. STUDY DESIGN: Interventional study. SUBJECTS/METHODS: Five adults with a non-progressive traumatic complete sensorimotor spinal cord injury who were using a wheelchair as a primary mode of mobility. Participants performed a personalized 6-week progressive locomotor training programme using a robotic exoskeleton 3 times/week for up to 60 min...
December 14, 2016: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27941855/clinical-predictors-of-neurological-outcome-within-72%C3%A2-h-after-traumatic-cervical-spinal-cord-injury
#18
Zhi Qiu, Fangyong Wang, Yi Hong, Junwei Zhang, Hehu Tang, Xiang Li, Shudong Jiang, Zhen Lv, Shujia Liu, Shizheng Chen, Jiesheng Liu
To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome measure and divided into dichotomous variables by two methods, i.e. "complete(AIS = A)/incomplete(AIS ≠ A) SCI" and "motor complete(AIS = A or B)/incomplete(AIS ≠ A and B) SCI". Relationships between evaluated factors and outcomes were investigated by univariate and multivariate methods...
December 12, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27939975/neuroprotection-and-secondary-damage-following-spinal-cord-injury-concepts-and-methods
#19
REVIEW
Brett J Hilton, Aaron J Moulson, Wolfram Tetzlaff
Neuroprotection refers to the attenuation of pathophysiological processes triggered by acute injury to minimize secondary damage. The development of neuroprotective treatments represents a major goal in the field of spinal cord injury (SCI) research. In this review, we discuss the strengths and limitations of the methodologies employed to assess secondary damage and neuroprotection in preclinical models of traumatic SCI. We also discuss modelling issues and how new tools might be exploited to study secondary damage and neuroprotection...
December 6, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27937140/evaluation-of-whole-brain-resting-state-functional-connectivity-in-spinal-cord-injury-a-large-scale-network-analysis-using-network-based-statistic
#20
Mayank Kaushal, Akinwunmi Oni-Orisan, Gang Chen, Wenjun Li, Jack Leschke, B Douglas Ward, Benjamin T Kalinosky, Matthew D Budde, Brian D Schmit, Shi-Jiang Li, Vaishnavi Muqeet, Shekar N Kurpad
Large-scale network analysis characterizes the brain as a complex network of nodes and edges to evaluate functional connectivity patterns. The utility of graph-based techniques has been demonstrated in an increasing number of resting-state functional MRI (rs-fMRI) studies in the normal and diseased brain. However, to our knowledge, graph theory has not been used to study the reorganization pattern of resting-state brain networks in patients with traumatic complete spinal cord injury (SCI). In the present analysis, we applied a graph-theoretical approach to explore changes to global brain network architecture as a result of SCI...
December 9, 2016: Journal of Neurotrauma
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