Oxana Semyachkina-Glushkovskaya, Konstantin Sergeev, Nadezhda Semenova, Andrey Slepnev, Anatoly Karavaev, Alexey Hramkov, Mikhail Prokhorov, Ekaterina Borovkova, Inna Blokhina, Ivan Fedosov, Alexander Shirokov, Alexander Dubrovsky, Andrey Terskov, Maria Manzhaeva, Valeria Krupnova, Alexander Dmitrenko, Daria Zlatogorskaya, Viktoria Adushkina, Arina Evsukova, Matvey Tuzhilkin, Inna Elizarova, Egor Ilyukov, Dmitry Myagkov, Dmitry Tuktarov, Jürgen Kurths
Anesthesia enables the painless performance of complex surgical procedures. However, the effects of anesthesia on the brain may not be limited only by its duration. Also, anesthetic agents may cause long-lasting changes in the brain. There is growing evidence that anesthesia can disrupt the integrity of the blood-brain barrier (BBB), leading to neuroinflammation and neurotoxicity. However, there are no widely used methods for real-time BBB monitoring during surgery. The development of technologies for an express diagnosis of the opening of the BBB (OBBB) is a challenge for reducing post-surgical/anesthesia consequences...
November 2, 2023: Biomolecules