keyword
https://read.qxmd.com/read/38215205/accuracy-of-two-continuous-glucose-monitoring-devices-during-aerobic-and-high-intensity-interval-training-in-individuals-with-type-1-diabetes
#21
JOURNAL ARTICLE
Alba Cuerda Del Pino, Rodrigo Martín-San Agustín, Alejandro José Laguna Sanz, Jose Luis Diez, Ana Palanca, Paolo Rossetti, Maria Gumbau-Gimenez, F Javier Ampudia-Blasco, Jorge Bondia
BBACKGROUND: This study aimed to evaluate the accuracy of Dexcom G6 (DG6) and FreeStyle Libre-2 (FSL2) during aerobic training and HIIT in individuals with type 1 diabetes (T1D). METHODS: Twenty-six males (mean age 29.3 ± 6.3 years and mean duration of diabetes 14.9 ± 6.1 years) participated in this study. Interstitial glucose levels were measured using DG6 and FSL2, while plasma glucose levels were measured every 10 min using YSI 2500 as the reference for glucose measurements in this study...
January 12, 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38195577/promising-sensors-for-pharmaceutical-pollutant-adsorption-using-clar-s-goblet-based-2d-membranes
#22
JOURNAL ARTICLE
Mahmoud A S Sakr, Mohamed A Saad, Omar H Abd-Elkader, Hazem Abdelsalam, Qinfang Zhang
This study focuses on the design of new 2D membranes from connected Clar's Goblet as a potential sensor for pharmaceutical pollutants, specifically the painkiller drugs aspirin, paracetamol, ibuprofen, and diclofenac. The electronic, optical, and interaction properties are investigated using density functional theory calculations. The Clar's Goblet membranes (CGMs) that were chosen are semiconductors with an energy gap of around 1.5 eV, according to energy gap calculations and density of states. Molecular electrostatic potential (ESP) analysis shows that CGMs have electrophilic and nucleophilic sites, suggesting their suitability for interacting with pharmaceutical pollutants...
January 9, 2024: Scientific Reports
https://read.qxmd.com/read/38194229/accuracy-of-a-continuous-glucose-monitor-during-pediatric-type-1-diabetes-inpatient-admissions
#23
JOURNAL ARTICLE
Erin Cobry, Laura Pyle, Lauren Waterman, Gregory P Forlenza, Lindsey Towers, Angela Karami, Emily Jost, Cari Berget, R Paul Wadwa
Objective Continuous glucose monitors (CGM) used for type 1 diabetes management are associated with lower HbA1c. CGMs are not approved for inpatient use, when close glucose monitoring and intensive insulin management are essential for optimal health. Accuracy data from adult hospitalizations have been published but pediatric data is limited. Design and Methods This retrospective review of Dexcom G6 data from youth with type 1 diabetes during hospitalization assessed CGM and matched (within 5 minutes) point of care (POC) and lab glucose values...
January 9, 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38133642/accuracy-and-safety-of-the-15-day-caresens-air-continuous-glucose-monitoring-system
#24
JOURNAL ARTICLE
Kyung-Soo Kim, Seung-Hwan Lee, Won Sang Yoo, Cheol-Young Park
Background: We evaluated the accuracy and safety of the CareSens Air, a novel real-time continuous glucose monitoring system (CGMS), during 15 days of use in adults with diabetes. Methods: Adults with either type 1 diabetes or type 2 diabetes requiring intensive insulin therapy participated at four sites in South Korea. All participants wore the sensor for 15 days. Participants were scheduled for four 8-h clinic sessions on Day 1, 5 ± 1, 10 ± 1, and 15. Accuracy was evaluated based on the proportion of continuous glucose monitoring (CGM) values within 15% of YSI values ≥100 mg/dL or within 15 mg/dL of YSI values <100 mg/dL (%15/15), along with the %20/20, %30/30, and %40/40 agreement rates...
April 2024: Diabetes Technology & Therapeutics
https://read.qxmd.com/read/38104898/associations-between-hypoglycemia-awareness-hypoglycemia-beliefs-and-continuous-glucose-monitoring-glycemic-profiles-and-anxiety-and-depression-symptoms-in-adults-with-type-1-diabetes-using-advanced-diabetes-technologies
#25
JOURNAL ARTICLE
Yu Kuei Lin, Emily Hepworth, Nicole de Zoysa, Jessica McCurley, Mary Ellen Vajravelu, Wen Ye, Gretchen A Piatt, Stephanie A Amiel, Simon J Fisher, Rodica Pop-Busui, James E Aikens
AIMS: To evaluate relationships between hypoglycemia awareness, hypoglycemia beliefs, and continuous glucose monitoring (CGM) glycemic profiles and anxiety and depression symptoms in adults with type 1 diabetes (T1D) who use CGM or automated insulin delivery devices. METHODS: A cross-sectional survey and data collections were completed with 196 T1D adults who used advanced diabetes technologies. We assessed hypoglycemia awareness (Gold instrument), hypoglycemia beliefs (Attitudes to Awareness of Hypoglycemia instrument), CGM glycemic profiles, demographics, and anxiety and depression symptoms (Hospital Anxiety and Depression Scale)...
December 15, 2023: Diabetes Research and Clinical Practice
https://read.qxmd.com/read/38005642/factory-calibrated-continuous-glucose-monitoring-systems-in-type-1-diabetes-accuracy-during-in-clinic-exercise-and-home-use
#26
JOURNAL ARTICLE
Sissel Banner Lundemose, Christian Laugesen, Ajenthen Gayathri Ranjan, Kirsten Nørgaard
Continuous glucose monitors (CGMs) are valuable tools for improving glycemic control, yet their accuracy might be influenced by physical activity. This study sought to assess the accuracy of the three latest factory-calibrated CGM systems available in Europe at the time the study was conducted, both during aerobic exercise and in typical daily scenarios. The accuracy evaluation, based on metrics such as the median absolute relative difference (MARD) and point and rate error-grid analyses (PEGA and REGA), involved 13 adults with type 1 diabetes...
November 18, 2023: Sensors
https://read.qxmd.com/read/37987208/effectiveness-of-continuous-glucose-monitoring-on-metrics-of-glycemic-control-in-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#27
JOURNAL ARTICLE
Stacey Uhl, Anuja Choure, Benjamin Rouse, Aggee Loblack, Peter Reaven
PURPOSE: To provide a systematic review and meta-analysis synthesizing the findings of randomized controlled trials (RCTs) of continuous glucose monitors (CGMs) in the management of adults with type 2 diabetes mellitus (T2DM) on glucose control and clinical outcomes. METHODS: MEDLINE, Embase, and Cochrane were searched for RCTs that assessed the effectiveness of real-time CGM (rt-CGM) or flash CGM (FGM) in adults (≥18 years) with T2DM that reported on at least 1 of the following outcomes: hemoglobin A1c (HbA1c), time in range, time in hyperglycemia, or time in hypoglycemia...
November 21, 2023: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/37970832/zooming-in-then-out-why-we-must-apply-human-centered-design-to-transform-diabetes-technology
#28
JOURNAL ARTICLE
Edward C Chao
Technological advances in devices, such as continuous glucose monitors (CGMs) or intermittently scanned continuous glucose monitors (isCGMs), do not necessarily by themselves translate to improved clinical outcomes or quality of life. Human-centered design (HCD) is an accessible, flexible process that could contribute to reducing the gap between current challenges and more optimal future solutions, by continuing to refine crucial considerations, such as usability. Starting with understanding the unmet needs of patients, cultivating novel and different collaborations, and applying humility to humanize technology are three facets underlying this approach...
November 16, 2023: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/37961419/glycaemic-variability-assessed-with-continuous-glucose-monitors-is-associated-with-diet-lifestyle-and-health-in-people-without-diabetes
#29
Sarah Berry, Kate Bermingham, Harry Smith, Javier Gonzalez, Emma Duncan, Ana Valdes, Paul Franks, Linda Delahanty, Hassan Dashti, Richard Davies, George Hadjigeorgiou, Jonathan Wolf, Andrew Chan, Tim Spector
Background Continuous glucose monitors (CGMs) provide high-frequency information regarding daily glucose variation and are recognised as effective for improving glycaemic control in individuals living with diabetes. Despite increased use in individuals with non-diabetic blood glucose concentrations (euglycemia), their utility as a health tool in this population remains unclear. Objectives To characterise variation in time in range (TIR) and glycaemic variability in large populations without diabetes or impaired glucose tolerance; describe associations between CGM-derived glycaemic metrics and metabolic and cardiometabolic health traits; identify key diet and lifestyle factors associated with TIR and glycaemic variability...
October 30, 2023: Research Square
https://read.qxmd.com/read/37906216/supporting-the-management-of-gestational-diabetes-mellitus-with-comprehensive-self-tracking-mixed-methods-study-of-wearable-sensors
#30
JOURNAL ARTICLE
Mikko Kytö, Saila Koivusalo, Heli Tuomonen, Lisbeth Strömberg, Antti Ruonala, Pekka Marttinen, Seppo Heinonen, Giulio Jacucci
BACKGROUND: Gestational diabetes mellitus (GDM) is an increasing health risk for pregnant women as well as their children. Telehealth interventions targeted at the management of GDM have been shown to be effective, but they still require health care professionals for providing guidance and feedback. Feedback from wearable sensors has been suggested to support the self-management of GDM, but it is unknown how self-tracking should be designed in clinical care. OBJECTIVE: This study aimed to investigate how to support the self-management of GDM with self-tracking of continuous blood glucose and lifestyle factors without help from health care personnel...
October 31, 2023: JMIR Diabetes
https://read.qxmd.com/read/37882585/addressing-disparities-in-technology-use-among-patients-with-type-1-diabetes-a-review
#31
JOURNAL ARTICLE
Sarah Kanbour, Estelle Everett
PURPOSE OF REVIEW: The benefits of continuous glucose monitors (CGMs) and insulin pumps in the management of type 1 diabetes are widely recognized. However, glaring disparities in access exist, particularly in groups that stand to benefit significantly from diabetes technology use. We will review recent data describing drivers of these disparities and approaches to address the disparities. RECENT FINDINGS: Several qualitative studies were published in recent years that have investigated the drivers of disparities reported over the past decades...
October 26, 2023: Current Opinion in Endocrinology, Diabetes, and Obesity
https://read.qxmd.com/read/37847371/two-novel-gck-mutations-in-chinese-patients-with-maturity-onset-diabetes-of-the-young
#32
JOURNAL ARTICLE
Tao Wang, Mengmeng Zhu, Yun Wang, Cheng Hu, Chen Fang, Ji Hu
PURPOSE: Heterozygous inactivating mutations in the glucokinase (GCK) gene result in the asymptomatic fasting hyperglycemia named as GCK-MODY or MODY2. The genetic testing can effectively avoid the misdiagnosis and inappropriate treatment for GCK-MODY. METHODS: A total of 25 unrelated families with MODY were screened for mutations in coding region of GCK by using direct sequencing. Three different bioinformatics tools such as PolyPhen2, Mutation Taster and PROVEAN were performed to predict the function of mutant proteins...
January 2024: Endocrine
https://read.qxmd.com/read/37788058/an-mhealth-text-messaging-program-providing-symptom-detection-training-and-psychoeducation-to-improve-hypoglycemia-self-management-intervention-development-study
#33
JOURNAL ARTICLE
Yu Kuei Lin, James E Aikens, Nicole de Zoysa, Diana Hall, Martha Funnell, Robin Nwankwo, Kate Kloss, Melissa J DeJonckheere, Rodica Pop-Busui, Gretchen A Piatt, Stephanie A Amiel, John D Piette
BACKGROUND: Hypoglycemia remains a challenge for roughly 25% of people with type 1 diabetes (T1D) despite using advanced technologies such as continuous glucose monitors (CGMs) or automated insulin delivery systems. Factors impacting hypoglycemia self-management behaviors (including reduced ability to detect hypoglycemia symptoms and unhelpful hypoglycemia beliefs) can lead to hypoglycemia development in people with T1D who use advanced diabetes technology. OBJECTIVE: This study aims to develop a scalable, personalized mobile health (mHealth) behavioral intervention program to improve hypoglycemia self-management and ultimately reduce hypoglycemia in people with T1D who use advanced diabetes technology...
October 3, 2023: JMIR Formative Research
https://read.qxmd.com/read/37784246/use-of-continuous-glucose-monitors-upon-hospital-discharge-of-people-with-diabetes-promise-barriers-and-opportunity
#34
JOURNAL ARTICLE
Tiffany Tian, Rachel E Aaron, Jane Jeffrie Seley, Rebecca Longo, Irina Nayberg, Guillermo E Umpierrez, Carol J Levy, David C Klonoff
Continuous glucose monitors (CGMs) have increasingly been used in ambulatory and inpatient or hospital settings to improve glycemic outcomes for people with diabetes. Given their capacity to aid individuals in avoiding hypo- and hyperglycemia, they may also be useful when transitioning from hospital to home by reducing rates of hospital readmissions and emergency department visits. Several types of barriers presently exist that make the deployment of CGMs at the time of hospital discharge problematic, including (1) regulatory, (2) behavioral, (3) logistical, (4) technical, (5) staffing, and (6) systemic issues...
October 2, 2023: Journal of Diabetes Science and Technology
https://read.qxmd.com/read/37761385/the-utility-and-safety-of-a-continuous-glucose-monitoring-system-cgms-in-asphyxiated-neonates-during-therapeutic-hypothermia
#35
JOURNAL ARTICLE
Lucia Giordano, Alessandro Perri, Eloisa Tiberi, Annamaria Sbordone, Maria Letizia Patti, Vito D'Andrea, Giovanni Vento
BACKGROUND: The present study was designed to assess the feasibility and reliability of a Continuous Glucose Monitoring System (CGMS) in a population of asphyxiated neonates during therapeutic hypothermia. METHODS: This non-randomized feasibility study was conducted in the Neonatal Intensive Care Unit (NICU) facilities of Fondazione Policlinico A. Gemelli IRCSS. Infants matching the criteria for hypothermic treatment were included in this study and were connected to the CGMS (Medtronic, Northridge, CA, USA) within the first 12 h of life...
September 21, 2023: Diagnostics
https://read.qxmd.com/read/37724489/error-traps-in-the-perioperative-management-of-children-with-type-1-diabetes
#36
REVIEW
M Hoagland, B Duggar, J Hamrick, G Todd Alonso, L Martin
Patients with type 1 diabetes mellitus (T1D) require insulin administration at all times to maintain euglycemia and metabolic stability. Insulin administration in the perioperative period is complicated by fasting requirements and perioperative stressors that can change the patient's insulin needs. In addition, many anesthesia providers are not familiar with insulin dosing strategies and technology, such as insulin pumps and continuous glucose monitors (CGMs), that are commonly used by patients with T1D. Errors in perioperative insulin administration can lead to hypoglycemia, hyperglycemia, and diabetic ketoacidosis...
January 2024: Paediatric Anaesthesia
https://read.qxmd.com/read/37710956/continuous-glucose-monitoring-systems-and-the-efficacy-of-acarbose-treatment-in-cystic-fibrosis-related-dysglycemia
#37
JOURNAL ARTICLE
Emrullah Arslan, Deniz Ozalp Kızılay, Yasemin Atik Altinok, Bahar Girgin Dundar, Arzu Jalilova, Gunay Demir, Samim Ozen, Sukran Darcan, Ruhsar Damla Goksen
Early detection of glycemic dysregulation and optimization of glycemic control at cystic fibrosis related diabetes (CFRD) is associated with improved pulmonary function and decreased mortality. The standard 2-hour oral glucose tolerance test (OGTT) is the current routine screening test for CFRD. However, hyperglycemia can be detected by continuous glucose monitoring systems (CGMS) in patients with normal OGTT evaluation. High-dose acarbose is an important alternative, in the treatment of glycemic dysregulation especially accompanied by hypoglycemia...
September 15, 2023: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/37606708/male-sterility-in-plants-an-overview-of-advancements-from-natural-cms-to-genetically-manipulated-systems-for-hybrid-seed-production
#38
REVIEW
Ranjana Gautam, Pawan Shukla, P B Kirti
The male sterility system in plants has traditionally been utilized for hybrid seed production. In last three decades, genetic manipulation for male sterility has revolutionized this area of research related to hybrid seed production technology. Here, we have surveyed some of the natural cytoplasmic male sterility (CMS) systems that existed/ were developed in different crop plants for developing male sterility-fertility restoration systems used in hybrid seed production and highlighted some of the recent biotechnological advancements in the development of genetically engineered systems that occurred in this area...
August 22, 2023: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://read.qxmd.com/read/37597151/a-review-on-food-subsystem-simulation-models-for-the-water-food-energy-nexus-development-perspective
#39
REVIEW
Hossein Akbari Variani, Abbas Afshar, Masoud Vahabzadeh, Amir Molajou
Agricultural crops are the primary food source because livestock and poultry products also indirectly depend on crops. A significant obstacle to adopting the water, food, and energy (WFE) nexus is the lack of a comprehensive and easy-to-use simulation model for the food subsystem focusing on crops. By reviewing the articles in Scopus and Google Scholar databases, WFE nexus studies can be divided into two categories: simulation-based and conceptual-based studies of WFE nexus. Based on the developmental perspective on food subsystem modeling in the WFE nexus, the conceptual studies were excluded, and the modeling studies were reviewed...
August 19, 2023: Environmental Science and Pollution Research International
https://read.qxmd.com/read/37592726/a-consensus-statement-for-continuous-glucose-monitoring-metrics-for-inpatient-clinical-trials
#40
JOURNAL ARTICLE
Elias K Spanakis, Curtiss B Cook, Kristen Kulasa, Joseph A Aloi, Lia Bally, Georgia Davis, Kathleen M Dungan, Rodolfo J Galindo, Carlos E Mendez, Francisco J Pasquel, Viral N Shah, Guillermo E Umpierrez, Rachel E Aaron, Tiffany Tian, Andrea M Yeung, Jingtong Huang, David C Klonoff
Diabetes Technology Society organized an expert consensus panel to develop metrics for research in the use of continuous glucose monitors (CGMs) in a hospital setting. The experts met virtually in small groups both before and after an April 13, 2023 virtual meeting of the entire panel. The goal of the panel was to develop consensus definitions in anticipation of greater use of CGMs in hospital settings in the future. Establishment of consensus definitions of inpatient analytical metrics will be easier to compare outcomes between studies...
August 17, 2023: Journal of Diabetes Science and Technology
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