keyword
MENU ▼
Read by QxMD icon Read
search

Baroreflex

keyword
https://www.readbyqxmd.com/read/29329321/impact-of-lipopolysaccharide-induced-acute-inflammation-on-baroreflex-controlled-sympathetic-arterial-pressure-regulation
#1
Takeshi Tohyama, Keita Saku, Toru Kawada, Takuya Kishi, Keimei Yoshida, Takuya Nishikawa, Hiroshi Mannoji, Kazuhiro Kamada, Kenji Sunagawa, Hiroyuki Tsutsui
BACKGROUND: Lipopolysaccharide (LPS) induces acute inflammation, activates sympathetic nerve activity (SNA) and alters hemodynamics. Since the arterial baroreflex is a negative feedback system to stabilize arterial pressure (AP), examining the arterial baroreflex function is a prerequisite to understanding complex hemodynamics under LPS challenge. We investigated the impact of LPS-induced acute inflammation on SNA and AP regulation by performing baroreflex open-loop analysis. METHODS: Ten anesthetized Sprague-Dawley rats were used...
2018: PloS One
https://www.readbyqxmd.com/read/29317289/baroreflex-stimulation-attenuates-central-but-not-peripheral-inflammation-in-conscious-endotoxemic-rats
#2
Fernanda Brognara, Jaci A Castania, Daniel P M Dias, Alexandre H Lopes, Rubens Fazan, Alexandre Kanashiro, Luis Ulloa, Helio C Salgado
We previously reported that activation of the baroreflex, a critical physiological mechanism controlling cardiovascular homeostasis, through electrical stimulation of the aortic depressor nerve attenuates joint inflammation in experimental arthritis. However, it is unknown whether baroreflex activation can control systemic inflammation. Here, we investigate whether baroreflex activation controls systemic inflammation in conscious endotoxemic rats. Animals underwent sham or electrical aortic depressor nerve stimulation initiated 10 min prior to a lipopolysaccharide (LPS) challenge, while inflammatory cytokine levels were measured in the blood, spleen, heart and hypothalamus 90 min after LPS treatment...
January 6, 2018: Brain Research
https://www.readbyqxmd.com/read/29316564/primary-prevention-of-stroke-in-chronic-kidney-disease-patients-a-scientific-update
#3
Stefana Catalina Bilha, Alexandru Burlacu, Dimitrie Siriopol, Luminita Voroneanu, Adrian Covic
BACKGROUND: Although chronic kidney disease (CKD) is an independent risk factor for stroke, official recommendations for the primary prevention of stroke in CKD are generally lacking. SUMMARY: We searched PubMed and ISI Web of Science for randomised controlled trials, observational studies, reviews, meta-analyses and guidelines referring to measures of stroke prevention or to the treatment of stroke-associated risk factors (cardiovascular disease in general and atrial fibrillation (AF), arterial hypertension or carotid artery disease in particular) among the CKD population...
January 9, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29316181/heart-rate-variability-and-baroreflex-sensitivity-in-bilateral-lung-transplant-recipients
#4
Timothée Fontolliet, Pietro Gianella, Vincent Pichot, Jean-Claude Barthélémy, Paola Gasche-Soccal, Guido Ferretti, Frédéric Lador
The effects of lung afferents denervation on cardiovascular regulation can be assessed on bilateral lung transplantation patients. The high-frequency component of heart rate variability is known to be synchronous with breathing frequency. Then, if heart beat is neurally modulated by breathing frequency, we may expect disappearance of high frequency of heart rate variability in bilateral lung transplantation patients. On 11 patients and 11 matching healthy controls, we measured R-R interval (electrocardiography), blood pressure (Portapres® ) and breathing frequency (ultrasonic device) in supine rest, during 10-min free breathing, 10-min cadenced breathing (0·25 Hz) and 5-min handgrip...
January 9, 2018: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/29313987/variable-role-of-carotid-bodies-in-cardiovascular-responses-to-exercise-hypoxia-and-hypercapnia-in-spontaneously-hypertensive-rats
#5
Wioletta Pijacka, Pedro L Katayama, Helio C Salgado, Gisele S Lincevicius, Ruy R Campos, Fiona D McBryde, Julian F R Paton
The carotid body has recently emerged as a promising therapeutic target for treating cardiovascular disease, however the potential impact of carotid bodies removal on the dynamic cardiovascular responses to acute stressors such as exercise, hypoxia and hypercapnia in hypertension is an important safety consideration that has not been studied. We first validated a novel surgical approach to selectively resect the carotid bodies bilaterally (CBR) sparing the carotid sinus baroreflex. Second, we evaluated the impact of CBR on the cardiovascular responses to exercise, hypoxia and hypercapnia in the conscious, chronically instrumented spontaneously hypertensive (SH) rats...
January 5, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29300244/sympathetic-and-baroreflex-abnormalities-in-the-uncomplicated-prediabetic-state
#6
Raffaella Dell'Oro, Fosca Quarti Trevano, Pierluigi Gamba, Claudia Ciuffarella, Gino Seravalle, Giuseppe Mancia, Guido Grassi
BACKGROUND: Neurogenic abnormalities characterize overt diabetic state. However, how early is their appearance in the clinical course of the disease is unclear. METHODS: In 26 normotensive and normoweight prediabetic patients, aged 45.2 ± 3.2 years (mean ± SEM), we assessed efferent postganglionic muscle sympathetic nerve traffic (MSNA, microneurography), spontaneous baroreflex sensitivity, and a number of hemodynamic and metabolic variables, including homeostatic model assessment (HOMA) index...
January 2, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29297736/increased-receptor-activity-modifying-protein-1-in-the-nervous-system-is-sufficient-to-protect-against-autonomic-dysregulation-and-hypertension
#7
Rasna Sabharwal, Bianca N Mason, Adisa Kuburas, Francois M Abboud, Andrew F Russo, Mark W Chapleau
Calcitonin gene-related peptide (CGRP) can cause migraines, yet it is also a potent vasodilator that protects against hypertension. Given the emerging role of CGRP-targeted antibodies for migraine prevention, an important question is whether the protective actions of CGRP are mediated by vascular or neural CGRP receptors. To address this, we have characterized the cardiovascular phenotype of transgenic nestin/hRAMP1 mice that have selective elevation of a CGRP receptor subunit in the nervous system, human receptor activity-modifying protein 1 (hRAMP1)...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29297147/one-year-cardiovascular-prognosis-of-the-randomized-controlled-short-term-heart-rate-variability-biofeedback-among-patients-with-coronary-artery-disease
#8
Li-Ching Yu, I-Mei Lin, Sheng-Yu Fan, Chin-Lung Chien, Tsung-Hsien Lin
PURPOSE: Heart rate variability biofeedback (HRV-BF) is an effective psychophysiological intervention, with short-term effects of increased autonomic nervous system homeostasis, strengthened baroreflex sensitivity, and decreased hostility in patients with coronary artery disease (CAD). The study examined the 1-year HRV-BF effect on cardiovascular prognosis of these patients. METHODS: Of 222 patients with CAD referred by cardiologists, 210 were screened and randomly assigned to the HRV-BF and control groups...
January 2, 2018: International Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29283975/sympathetic-baroreceptor-regulation-during-hypoxic-hypotension-in-humans-new-insights
#9
Christophe Janssen, Guido Grassi, Dominique Laude, Philippe van de Borne
BACKGROUND: Baroreceptor activation by a continuous infusion of phenylephrine selectively abolishes the muscle sympathetic nerve activity (MSNA) response to hypoxia in humans. Baroreceptor deactivation enhances the MSNA rise during hypoxia in animals. Whether this is true in humans is unknown and was tested in the present study. METHODS: We assessed MSNA responses elicited by isocapnic hypoxia (10% O2 in N2) during baroreflex loading and unloading with phenylephrine and nitroprusside, respectively, in 19 healthy volunteers...
December 27, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29281076/impaired-baroreflex-sensitivity-carotid-stiffness-and-exaggerated-exercise-blood-pressure-a-community-based-analysis-from-the-paris-prospective-study-iii
#10
James E Sharman, Pierre Boutouyrie, Marie-Cécile Perier, Frédérique Thomas, Catherine Guibout, Hakim Khettab, Bruno Pannier, Stéphane Laurent, Xavier Jouven, Jean-Philippe Empana
Aims: People with exaggerated exercise blood pressure (BP) have adverse cardiovascular outcomes. Mechanisms are unknown but could be explained through impaired neural baroreflex sensitivity (BRS) and/or large artery stiffness. This study aimed to determine the associations of carotid BRS and carotid stiffness with exaggerated exercise BP. Methods and results: Blood pressure was recorded at rest and following an exercise step-test among 8976 adults aged 50 to 75 years from the Paris Prospective Study III...
December 21, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29272958/reduced-neural-baroreflex-sensitivity-is-related-to-enhanced-endothelial-function-in-patients-with-end-stage-liver-disease
#11
Adrienn Sárközi, Domonkos Cseh, Zsuzsanna Gerlei, Márk Kollai
OBJECTIVES: Reduced baroreflex sensitivity (BRS) is a frequent complication in end-stage liver disease, but the underlying mechanism is unknown. We investigated the mechanical and neural components of BRS. Increased nitric oxide (NO) production has been reported in end-stage liver failure. Based on earlier experiments, we hypothesised that enhanced endothelial function might affect baroreflex function. Therefore, we explored the relation between endothelial function and the components of BRS...
December 22, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29261644/age-related-changes-in-baroreflex-sensitivity-and-cardiac-autonomic-tone-in-children-mirrored-by-regional-brain-gray-matter-volume-trajectories
#12
Mark W DiFrancesco, Abu Shamsuzzaman, Keith B McConnell, Stacey L Ishman, Nanhua Zhang, Guixia Huang, Monir Hossain, Raouf S Amin
BackgroundThe baroreflex and central autonomic brain regions together control the cardiovascular system. Baroreflex sensitivity (BRS) decreases with age in adults. Age-related changes in brain regions for cardiovascular control in children are unknown. We studied age-related changes in BRS, cardiac autonomic tone, and gray matter volume (GMV) of brain regions associated with cardiovascular control.MethodsBeat-to-beat blood pressure and heart rate (HR) were recorded in 49 children (6-14 years old). Spontaneous BRS was calculated by the sequence method...
December 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29235056/separating-arterial-pressure-increases-and-decreases-in-assessing-cardiac-baroreflex-sensitivity-via-sequence-and-bivariate-phase-rectified-signal-averaging-techniques
#13
Beatrice De Maria, Vlasta Bari, Marco Ranucci, Valeria Pistuddi, Giovanni Ranuzzi, Anielle C M Takahashi, Aparecida M Catai, Laura Dalla Vecchia, Sergio Cerutti, Alberto Porta
Cardiac baroreflex (cBR) is activated by both arterial pressure (AP) increases and decreases. Sequence method, a widely utilized tool assessing cBR sensitivity (cBRS) from spontaneous heart period (HP) and systolic AP (SAP) variations, allows the separated computation of cBRS from positive and negative SAP variations. The recently proposed phase-rectified signal averaging (PRSA) method has the same feature but it has been applied so far solely to positive SAP variations. We adapted the PRSA method to compute cBRS over negative SAP variations and we compared the results with those derived from sequence method over two protocols: (i) graded head-up tilt (HUT) at 15, 30, 45, 60, and 75° in 19 healthy subjects and (ii) general anesthesia induction in 118 patients undergoing coronary artery bypass graft surgery...
December 13, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29222949/a-switch-from-gaba-inhibition-to-excitation-of-vasopressin-neurons-exacerbates-the-development-angiotensin-ii-dependent-hypertension
#14
Aaron K Korpal, Su Young Han, Daryl O Schwenke, Colin H Brown
Hypothalamic magnocellular neurons secrete vasopressin into the systemic circulation to maintain blood pressure by increasing renal water reabsorption and by vasoconstriction. When blood pressure rises, baroreflex activation normally inhibits vasopressin neurons via activation of GABAergic inputs. However, plasma vasopressin levels are paradoxically elevated in several models of hypertension and in some patients with essential hypertension, despite increased blood pressure. We have previously shown that vasopressin neuron activity is increased early in the development of moderate angiotensin II-dependent hypertension via blunted baroreflex inhibition of vasopressin neurons...
December 9, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29217881/reduced-baroreflex-sensitivity-decreased-heart-rate-variability-with-increased-arterial-stiffness-in-predialysis
#15
C Lal, M Kaur, A K Jaryal, K K Deepak, D Bhowmik, S K Agarwal
High cardiovascular morbidity and mortality is observed in predialytic chronic kidney disease (CKD) patients. The underlying mechanism of cardiovascular dysfunction often remains unclear. The present study was designed to perform multiparametric assessment of baroreflex sensitivity (BRS), arterial stiffness indices, and cardiovascular variabilities (heart rate variability [HRV] and blood pressure variability [BPV]) together in predialytic CKD patients; compare it with normal healthy controls; and determine their relationships in predialytic nondiabetic CKD patients...
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29214015/effect-of-spinal-manipulative-treatment-on-cardiovascular-autonomic-control-in-patients-with-acute-low-back-pain
#16
Mohamed Younes, Karine Nowakowski, Benoit Didier-Laurent, Michel Gombert, François Cottin
Background: This study aimed to quantify the effect of spinal manipulative treatment (SMT) from an analysis of baroreflex, systolic blood pressure and heart rate variability (HRV) on patients with acute back pain. It was hypothesized that SMT would increase the parasympathetic cardiovascular autonomic control. Methods: Twenty-two patients with acute back pain were randomly divided into two groups: one receiving sham treatment (Sham) and the other receiving SMT. Recordings were completed during the first day and the seventh day, immediately before and after treatment on both days...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29212671/influence-of-age-and-gender-on-the-phase-and-strength-of-the-relation-between-heart-period-and-systolic-blood-pressure-spontaneous-fluctuations
#17
Juliana C Milan-Mattos, Alberto Porta, Natália M Perseguini, Vinicius Minatel, Patricia Rehder-Santos, Anielle C M Takahashi, Stela M Mattiello, Aparecida M Catai
Aging affects baroreflex regulation. The effect of senescence on baroreflex control was assessed from spontaneous fluctuations of heart period (HP) and systolic arterial pressure (SAP) through the HP-SAP gain, while the HP-SAP phase and strength are usually disregarded. This study checks whether the HP-SAP phase and strength, as estimated respectively via the phase of the HP-SAP cross-spectrum (PhHP-SAP) and squared coherence function (K2HP-SAP), varies with age in healthy individuals and trends are gender-dependent...
December 6, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29209423/the-physiological-effects-of-slow-breathing-in-the-healthy-human
#18
Marc A Russo, Danielle M Santarelli, Dean O'Rourke
Slow breathing practices have been adopted in the modern world across the globe due to their claimed health benefits. This has piqued the interest of researchers and clinicians who have initiated investigations into the physiological (and psychological) effects of slow breathing techniques and attempted to uncover the underlying mechanisms. The aim of this article is to provide a comprehensive overview of normal respiratory physiology and the documented physiological effects of slow breathing techniques according to research in healthy humans...
December 2017: Breathe
https://www.readbyqxmd.com/read/29206785/three-weeks-of-overload-training-increases-resting-muscle-sympathetic-activity
#19
Alexandra M Coates, Anthony V Incognito, Jeremy D Seed, Connor J Doherty, Philip J Millar, Jamie F Burr
PURPOSE: Overload training is hypothesized to alter autonomic regulation, though interpretations using indirect measures of heart rate variability are conflicting. The aim of the present study was to examine the effects of overload training on muscle sympathetic nerve activity (MSNA), a direct measure of central sympathetic outflow, in recreational endurance athletes. METHODS: Measurements of heart rate variability, cardiac baroreflex sensitivity (BRS), MSNA (microneurography), and sympathetic BRS were obtained in seventeen healthy triathletes and cyclists after 1-week of reduced training (baseline) and following 3-weeks of either regular (CON, n=7) or overload (OL, n=10) training...
December 2, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29193139/early-signs-of-cardiovascular-dysregulation-in-young-adult-binge-drinkers
#20
Evgeny G Vaschillo, Bronya Vaschillo, Jennifer F Buckman, Sydney Heiss, Gurpreet Singh, Marsha E Bates
Binge drinking is widespread on American college campuses, but its effects on the cardiovascular system are poorly understood. This study sought evidence of preclinical cardiovascular changes in binge drinking young adults (n = 24) compared to nondrinking (n = 24) and social drinking (n = 23) peers during baseline, paced sighing (0.033 Hz), and paced breathing (0.1 Hz) tasks. Binge drinkers showed consistent but often statistically nonsignificant evidence of greater sympathetic activation and reduced baroreflex sensitivity...
November 29, 2017: Psychophysiology
keyword
keyword
51514
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"