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https://www.readbyqxmd.com/read/28263020/from-actinic-keratosis-to-squamous-cell-carcinoma-pathophysiology-revisited
#1
REVIEW
M T Fernandez Figueras
The precursor of most cutaneous invasive squamous cell carcinomas (iSCCs) is intraepithelial UV-induced damage, known as field cancerization, which can eventually transform into actinic keratosis (AK). Although AK is the most common precursor of iSCC, many AKs will either persist in the same stage or regress, while only a few will progress into iSCC. Nevertheless, because the progression of individual AKs cannot be predicted, it has been proposed that all AKs, regardless of the grade, should be carefully monitored and appropriately treated in clinical practice...
March 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28243499/nail-apparatus-melanoma-initially-diagnosed-as-nail-matrix-blue-nevus-a-case-report-with-dermatoscopy-and-dermatopathology
#2
Bengu Nisa Akay, Aylin Okcu Heper, Luc Thomas, Brigitte Balme, Simon Clark, Cliff Rosendahl
We present a case of nail apparatus melanoma in a 50-year-old woman presenting as new and changing longitudinal melanonychia of the right thumb. Very heavy melanin pigmentation involving both the epidermis and dermis interfered with dermatopathological assessment, which initially leads to a diagnosis of nail matrix blue nevus. After consultation with a specialist multidisciplinary clinic the diagnosis was revised to invasive melanoma, a diagnosis consistent with the clinical and dermatoscopic assessment.
January 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28243488/-twin-lesions-which-one-is-the-bad-one-improvement-of-clinical-diagnosis-with-reflectance-confocal-microscopy
#3
Secil Saral, Daniela Hartmann, Valerie Letulè, Thomas Ruzicka, Cristel Ruini, Tanja von Braunmühl
BACKGROUND: In vivo reflectance confocal microscopy (RCM) is a novel non-invasive diagnostic tool, which is used to differentiate skin lesions. Even in lesions with similar dermatoscopic images, RCM may improve diagnostic accuracy. METHODS: Three sets of false "twin lesions" with similar macroscopic and dermatoscopic images are matched. All lesions are evaluated with RCM and lesions are excised for further evaluation. Corresponding features in confocal images, dermatoscopy and histopathology are discussed...
January 2017: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/28240407/the-significance-of-blue-color-in-dermatoscopy
#4
Mirjana Popadic, Christoph Sinz, Harald Kittler
BACKGROUND AND OBJECTIVES: Skin lesions with blue color are frequently excised to rule out malignancy. The objective of the present study was to investigate the significance of blue color. METHODS: We retrospectively scanned dermatoscopic images for blue color and classified them according to pattern analysis. RESULTS: Of 1,123 pigmented skin lesions, 144 (12.8 %) showed blue color, 92 of which (63.9 %) were malignant. Among lesions with blue color, the most common benign diagnoses were nevi (n = 35, 24...
February 27, 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28214381/the-value-of-reflectance-confocal-microscopy-in-diagnosis-of-flat-pigmented-facial-lesions-a-prospective-study
#5
E Wurm, G Pellacani, C Longo, H P Soyer, S Gonzalez, R Hofmann-Wellenhof, V Ahlgrimm-Siess, P Guitera, C Sinz, H Kittler
BACKGROUND: Flat pigmented facial lesions are difficult to diagnose even with dermatoscopy. It is controversial how additional information obtained by in vivo reflectance confocal microscopy (RCM) impacts the diagnosis and management. OBJECTIVE: To examine what in vivo reflectance confocal microscopy of flat pigmented facial lesions adds to clinical examination using dermatoscopy including digital dermatoscopic monitoring. METHODS: We prospectively collected 70 cases of flat pigmented facial lesions and recorded diagnoses and management decisions by experts based on direct clinical examination aided by dermatoscopy including digital dermatoscopic monitoring and by remote experts who reviewed the corresponding confocal images...
February 18, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28099598/dermatoscopy-guided-therapy-of-pigmented-basal-cell-carcinoma-with-imiquimod
#6
Husein Husein-ElAhmed, Maria Antonia Fernandez-Pugnaire
BACKGROUND: Dermatoscopy is a non-invasive diagnostic tool used to examine skin lesions with an optical magnification. It has been suggested as a useful tool for monitoring therapeutic response in lentigo maligna patients treated with imiquimod. OBJECTIVE: To examine the accuracy of dermatoscopy as a tool to monitor the therapeutic response of pigmented basal cell carcinoma treated with imiquimod. METHOD: The authors designed a prospective study...
November 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28087035/the-anal-groove-sign-the-use-of-dermatoscopy-for-identification-of-ixodes-ticks
#7
Deirdre M Connolly, Jason B Lee
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28076343/pigmented-basal-cell-carcinoma-mimicking-a-superficial-spreading-melanoma
#8
Paula Hasbún Acuña, Roberto Cullen Aravena, César Maturana Donaire, Raúl Ares Mora, Ninoska Porras Kusmanic
Basal cell carcinoma is the most common form of skin cancer, especially in elderly people. Pigmented basal cell carcinoma is a rare subtype and has been described in the literature as a nodular and hyperpigmented lesion; rarely, it can appear as an extensive pigmented plate, which may be clinically indistinguishable from superficial spreading melanoma and Bowen disease. Dermatoscopy has a high sensitivity in the diagnosis of basal cell carcinoma. When Menzies criteria are used; however, the final diagnosis is made by histopathology...
December 20, 2016: Medwave
https://www.readbyqxmd.com/read/28061322/long-pulsed-1064-nm-nd-yag-laser-for-the-treatment-of-onychomycosis
#9
Domenico Piccolo, Dimitra Kostaki, Ester Del Duca, Giovanni Cannarozzo, Mario Sannino, Steven Nisticò
OBJECTIVE: The aim of this study is to evaluate the efficacy of long-pulsed 1064-nm Nd:YAG laser in penetrating tissue and targeting the fungal overgrowth in the nail plate. BACKGROUND: Onychomycosis is the most frequent nail disorder. Current treatments include oral and topical antifungal agents, photodynamic therapy, and surgical approaches such as mechanical, chemical, or surgical nail avulsion. Moreover, the use of lasers to treat nail diseases has been approved in the United States by the Food and Drug Administration (FDA)...
December 30, 2016: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/27896853/melanomas-versus-nevi-in-high-risk-patients-under-long-term-monitoring-with-digital-dermatoscopy-do-melanomas-and-nevi-already-differ-at-baseline
#10
P Tschandl, L Hofmann, C Fink, H Kittler, H A Haenssle
BACKGROUND: What lesions to select for a most efficient dermatoscopic monitoring of patients with multiple nevi remains an unresolved issue. OBJECTIVE: To compare the grade of atypia of melanomas and nevi of the same patient at baseline. METHODS: Prospective observational study using 236 dermatoscopic baseline images (59 quartets from 59 patients, each including 1 melanoma detected during follow-up and 3 nevi). Dermatologists (n=26) were asked to assess the "grade of dermatoscopic atypia" on a numerical scale and to identify the melanomas...
November 29, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27882878/and-next%C3%A2-adnexa-intraoperative-dermatoscopy-in-the-assessment-of-longitudinal-melanonychia
#11
Margarida Moura Valejo Coelho, Virgínia Coelho de Sousa, Joana Cabete, André Lencastre
No abstract text is available yet for this article.
December 1, 2016: European Journal of Dermatology: EJD
https://www.readbyqxmd.com/read/27881943/number-and-size-of-acquired-melanocytic-nevi-and-affecting-risk-factors-in-cases-admitted-to-the-dermatology-clinic
#12
Ayşegül Yalçınkaya İyidal, Ülker Gül, Arzu Kılıç
INTRODUCTION: The size and number of acquired melanocytic nevi (AMN) and presence of dysplastic nevi are the leading risk factors that should be recognized in the development of malignant melanoma. AIM: To evaluate AMN and risk factors in the development of AMN in all age groups admitted to a dermatology outpatient clinic. MATERIAL AND METHODS: Four hundred and twelve patients who were admitted to the dermatology outpatient clinic for any dermatological symptom and who accepted to participate in the study were randomly included in the study...
October 2016: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/27866663/-dermatoscopy-of-breast-melanoma-in-women
#13
A Marchetti, L Thomas, S Dalle
No abstract text is available yet for this article.
January 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27836251/-balloon-cell-nevus-correlation-between-dermatopathology-and-dermatoscopy
#14
P Huet, G Barnéon, B Cribier
No abstract text is available yet for this article.
February 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/27828629/dermatoscopic-findings-of-pigmented-purpuric-dermatosis
#15
Dilek Biyik Ozkaya, Nazan Emiroglu, Ozlem Su, Fatma Pelin Cengiz, Anil Gulsel Bahali, Pelin Yildiz, Cuyan Demirkesen, Nahide Onsun
Background: Pigmented purpuric dermatosis is a chronic skin disorder of unknown aetiology characterised by symmetrical petechial and pigmented macules, often confined to the lower limbs. The aetiology of pigmented purpuric dermatosis is unknown. Dermatoscopy is a non-invasive diagnostic technique that allows the visualisation of morphological features invisible to the naked eye; it combines a method that renders the corneal layer of the skin translucent with an optical system that magnifies the image projected onto the retina...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/27784525/cutaneous-collagenous-vasculopathy-associated-benign-pigmented-purpura
#16
Warren R Heymann
A 68-year-old woman presented with an asymptomatic eruption predominantly on the proximal pretibial region of the right lower extremity, which had been present for many months. Her medical history was remarkable for diabetes and hypothyroidism. Physical examination demonstrated "cayenne pepper"-like brown macules, scattered petechiae, and multiple minute, blanching telangiectasias (Figure 1) that were more evident on dermatoscopy (Figure 2). The clinical differential diagnosis included a benign pigmented purpura (BBP; Schamberg type), telangiectasia macularis eruptiva perstans, cutaneous T-cell lymphoma, essential telangiectasia, and cutaneous collagenous vasculopathy (CCV)...
2016: Skinmed
https://www.readbyqxmd.com/read/27672409/improving-treatment-of-erythematotelangiectatic-rosacea-with-laser-and-or-topical-therapy-through-enhanced-discrimination-of-its-clinical-features
#17
REVIEW
Giuseppe Micali, Peter Arne Gerber, Francesco Lacarrubba, Gregor Schäfer
Rosacea is a chronic inflammatory disease that can present with a variety of cutaneous symptoms. Erythematotelangiectatic rosacea is a subtype characterized by flushing (transient erythema), persistent central facial erythema (background erythema), and telangiectasias. The severity of individual symptoms differs in each patient, which can complicate the selection of an appropriate treatment strategy. Evaluation of these specific symptoms has been greatly improved by the routine use of diagnostic tools such as (video) dermatoscopy...
July 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/27650743/dermatoscopy-in-general-practice
#18
C Rosendahl
No abstract text is available yet for this article.
October 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27559506/clinical-and-dermatoscopic-features-of-porokeratosis-palmaris-et-plantaris
#19
Satish Udare, Karishma Hemmady
A dermatoscope is an important tool in a dermatologist's armamentarium as it can eliminate the need for a biopsy in a wide array of conditions. Porokeratosis was described by Mibelli and Respighi in 1893, as a disorder of keratinization which on the basis of distribution patterns was described as five clinical variants that portrayed a coronoid lamella on histopathology. We describe a case of asymptomatic, long-standing palmar and plantar pits, which on dermatoscopy showed features suggestive of porokeratosis, which was later reconfirmed by histopathologic sections...
July 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27545710/the-diagnosis-and-treatment-of-nail-disorders
#20
Uwe Wollina, Pietro Nenoff, Gunter Haroske, Holger A Haenssle
BACKGROUND: Nail disorders can arise at any age. About half of all nail disorders are of infectious origin, 15% are due to inflammatory or metabolic conditions, and 5% are due to malignancies and pigment disturbances. The differential diagnosis of nail disorders is often an area of uncertainty. METHODS: This review is based on publications and guidelines retrieved by a selective search in PubMed, including Cochrane reviews, meta-analyses, and AWMF guidelines. RESULTS: Nail disorders are a common reason for derma - tologic consultation...
July 25, 2016: Deutsches Ärzteblatt International
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