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https://www.readbyqxmd.com/read/29149678/housing-conditions-and-birth-outcomes-the-national-child-development-study
#1
Emily W Harville, Felicia A Rabito
BACKGROUND: Despite their importance to respiratory and other health outcomes, housing conditions have been little-studied with respect to perinatal outcomes. METHODS: 1927 participants in the British National Child Development Study reported on housing conditions and pregnancy outcomes, including presence/severity of mold/dampness; type of heating; and whether remodeling of various sorts had been conducted. Crowding, based on the number of people in the residence and the number of rooms, was also considered...
November 14, 2017: Environmental Research
https://www.readbyqxmd.com/read/29149439/trends-in-utilization-of-outpatient-respiratory-syncytial-virus-prophylaxis-with-palivizumab-among-medicaid-and-commercially-insured-infants
#2
Melissa Pavilack, Robert A Clifford, Tara Gonzales, Amanda M Kong, Sally Wade, Kimmie K McLaurin
INTRODUCTION: Palivizumab is indicated for the prevention of respiratory syncytial virus (RSV) infection in high-risk children. Previous palivizumab utilization studies examined prior authorization claims but did not examine utilization within insured populations as a whole. This study describes outpatient palivizumab utilization trends and characterizes high-risk infants receiving palivizumab within Medicaid- and commercially insured populations. METHODS: Infants born July 1, 2003 through June 30, 2013 were identified in the MarketScan(®) Multistate Medicaid and Commercial claims databases...
November 17, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29149032/optimal-line-and-tube-placement-in-very-preterm-neonates-an-audit-of-practice
#3
Daragh Finn, Hannah Kinoshita, Vicki Livingstone, Eugene M Dempsey
BACKGROUND: Placement of endotracheal tubes (ETTs) and umbilical catheters (UCs) is essential in very preterm infant care. The aim of this study was to assess the effect of an educational initiative to optimize correct placement of ETTs and UCs in very preterm infants. METHODS: A pre-post study design, evaluating optimal radiological position of ETTs and UCs in the first 72 h of life in infants <32 weeks gestational age (GA) was performed. Baseline data was obtained from a preceding 34-month period...
November 17, 2017: Children
https://www.readbyqxmd.com/read/29148822/the-effect-of-a-silymarin-phosphatidylserine-and-galega-galactagogue-on-mothers-of-preterm-infants-milk-production
#4
Francesca Serrao, Mirta Corsello, Costantino Romagnoli, Vito D'Andrea, Enrico Zecca
AIMS: To investigate the efficacy of a galactagogue, containing Sylimarin-phosphatidylserine (SILITIDIL) and galega consumed in the first month after delivery by mothers of preterm infants, in maintaining milk production during the first 3-6 months after delivery. MATERIALS AND METHODS: Mothers of infants born at gestational age (GA) between 27 and 32 weeks, enrolled in our previous prospective, double-blind, randomized trial and randomly allocated to receive either the galactagogue (GG) or a placebo (PG), were asked about their milk production at 3 and 6 months after delivery...
November 17, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29148239/metabolic-signature-of-microvescicles-from-umbilical-cord-mesenchimal-stem-cells-of-preterm-and-term-infants
#5
Maurizio Bruschi, Laura Santucci, Silvia Ravera, Martina Bartolucci, Andrea Petretto, Daniela Calzia, Gianmarco Ghiggeri, Luca A Ramenghi, Giovanni Candiano, Isabella Panfoli
PURPOSE: Microvesicles, 200-1000 nm bodies budding from the cell plasma membrane, are a promising source of biomarkers. This study aimed at comparing the proteome of Microvesicles collected by ultracentrifugation from cultured Mesenchymal Stem Cells from Human Umbilical Cord of Preterm newborns(<34-weeks gestational age) in comparison to infants at Term(≥37 weeks). This discovery study was designed to establish the signature of prematurity. EXPERIMENTAL DESIGN: Orbitrap mass spectrometry, statistical, bioinformatics and biochemical analyses were employed...
November 16, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/29147889/association-of-il-10-gene-polymorphism-819c%C3%A2-%C3%A2-t-592c%C3%A2-%C3%A2-a-and-1082g%C3%A2-%C3%A2-a-with-preterm-birth
#6
Monika Pandey, Shally Awasthi, Urmila Singh, Abbas Ali Mahdi
OBJECTIVE: To analyze the association of IL-10 gene and its polymorphisms with preterm birth (PTB). METHODS: Five hundred and fifty nine women with term birth and 559 with preterm birth were recruited from Lucknow, India. Genetic association analysis was conducted between cases and controls. Subjects recruited as cases were women (aged between 18-40 y) with singleton delivery before 37 wk of gestation and controls were with delivery after or on 37 wk. The genotyping was performed for rs1800871, rs1800872 and rs1800896 for assessing the allelic distribution, haplotypic association and linkage disequilibrium analysis...
November 17, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29147839/screening-accuracy-of-the-brief-infant-toddler-social-emotional-assessment-to-identify-autism-spectrum-disorder-in-toddlers-born-at-less-than-30%C3%A2-weeks-gestation
#7
Kelly M Boone, Anne K Brown, Sarah A Keim
Despite the higher prevalence of autism spectrum disorder (ASD) in children born preterm, valid screening tools for use in preterm populations are lacking. We aimed to evaluate the screening accuracy of the Brief Infant Toddler Social-Emotional Assessment (BITSEA) and to compare it to the Pervasive Developmental Disorders Screening Test-II, Stage 2, Developmental Clinic Screener (PDDST-II-DCS) in identifying ASD diagnosis in toddlers born at < 30 weeks' gestation. Caregivers (94% mothers) of 555 children completed questionnaires (BITSEA, PDDST-II-DCS, socio-demographics) when the children (58% male) were 18-36 months...
November 17, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29146572/cognitive-trajectories-from-infancy-to-early-adulthood-following-birth-before-26-weeks-of-gestation-a-prospective-population-based-cohort-study
#8
Louise Linsell, Samantha Johnson, Dieter Wolke, Helen O'Reilly, Joan K Morris, Jennifer J Kurinczuk, Neil Marlow
OBJECTIVE: To determine the trajectory of cognitive test scores from infancy to adulthood in individuals born extremely preterm compared with term-born individuals. DESIGN: A prospective, population-based cohort study. SETTING: 276 maternity units in the UK and Ireland. PATIENTS: 315 surviving infants born less than 26 completed weeks of gestation recruited at birth in 1995 and 160 term-born classroom controls recruited at age 6...
November 16, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29146112/different-concentrations-of-docosahexanoic-acid-supplement-during-lactation-result-in-different-outcomes-in-preterm-sprague-dawley-rats
#9
Qian Wang, Chunhong Jia, Xiaohua Tan, Fan Wu, Xinqi Zhong, Zhiwen Su, Weiwen Sun, Qiliang Cui
PROPOSE: In this study, we evaluated the effects of different concentrations of docosahexanoic acid (DHA) supplement on preterm Sprague-Dawley rat pups, and in parallel, measured the phosphorylation activity of the mTOR pathway in the hippocampal CA1 area. METHODS: Preterm Sprague-Dawley rat pups were randomly assigned to experimental groups which included; a sufficient DHA group (100 mg/kg/day); an enriched DHA group (300 mg/kg/day); an excess DHA group (800 mg/kg/day); and a deficient DHA group (normal saline gavage 0...
November 13, 2017: Brain Research
https://www.readbyqxmd.com/read/29146008/heat-and-pregnancy-related-emergencies-risk-of-placental-abruption-during-hot-weather
#10
Siyi He, Tom Kosatsky, Audrey Smargiassi, Marianne Bilodeau-Bertrand, Nathalie Auger
INTRODUCTION: Outdoor heat increases the risk of preterm birth and stillbirth, but the association with placental abruption has not been studied. Placental abruption is a medical emergency associated with major morbidity and mortality in pregnancy. We determined the relationship between ambient temperature and risk of placental abruption in warm seasons. MATERIAL AND METHODS: We performed a case-crossover analysis of 17,172 women whose pregnancies were complicated by placental abruption in Quebec, Canada from May to October 1989-2012...
November 13, 2017: Environment International
https://www.readbyqxmd.com/read/29145913/goal-setting-deficits-at-13-years-in-very-preterm-born-children
#11
Kristina M Haebich, Catherine Willmott, Rachel Ellis, Alice C Burnett, Shannon E Scratch, Leona Pascoe, Megan M Spencer-Smith, Jeanie L Y Cheong, Terrie E Inder, Lex W Doyle, Deanne K Thompson, Peter J Anderson
OBJECTIVES: Preterm children demonstrate deficits in executive functions including inhibition, working memory, and cognitive flexibility; however, their goal setting abilities (planning, organization, strategic reasoning) remain unclear. This study compared goal setting abilities between very preterm (VP: <30 weeks/<1250 grams) and term born controls during late childhood. Additionally, early risk factors (neonatal brain abnormalities, medical complications, and sex) were examined in relationship to goal setting outcomes within the VP group...
November 17, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29145693/early-erythropoiesis-stimulating-agents-in-preterm-or-low-birth-weight-infants
#12
REVIEW
Arne Ohlsson, Sanjay M Aher
BACKGROUND: Preterm infants have low plasma levels of erythropoietin (EPO), providing a rationale for the use of erythropoiesis-stimulating agents (ESAs) to prevent or treat anaemia and to provide neuro protection and protection against necrotising enterocolitis (NEC). Darbepoetin (Darbe) and EPO are currently available ESAs. OBJECTIVES: To assess the effectiveness and safety of ESAs (erythropoietin (EPO) and/or Darbe) initiated early (before eight days after birth) compared with placebo or no intervention in reducing red blood cell (RBC) transfusions, adverse neurological outcomes, and feeding intolerance including necrotising enterocolitis (NEC) in preterm and/or low birth weight infants...
November 16, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29145579/progesterone-the-maternal-immune-system-and-the-onset-of-parturition-in-the-mouse
#13
Lydia F Edey, Hector Georgiou, Kieran P O'Dea, Sam Mesiano, Bronwen R Herbert, Kaiyu Lei, Renyi Hua, Danijela Markovic, Simon N Waddington, David MacIntyre, Philip Bennett, Masao Takata, Mark R Johnson
The role of progesterone (P4) in the regulation of the local (uterine) and systemic innate immune system, myometrial expression of connexin 43 (Cx-43) and cyclooxygenase 2 (COX-2) and the onset of parturition was examined in: 1) naïve mice delivering at term; 2) E16 mice treated with RU486 (P4-antagonist) to induce preterm parturition; and 3) in mice treated with P4 to prevent term parturition.In naïve mice, myometrial neutrophil and monocyte numbers peaked at E18 and declined with the onset of parturition...
November 14, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/29145319/primary-myelofibrosis-and-pregnancy-outcomes-after-low-molecular-weight-heparin-administration-a-case-report-and-literature-review
#14
Roxana Elena Bohîlţea, Monica Mihaela Cîrstoiu, Crîngu Antoniu Ionescu, Emilia Niculescu-Mizil, Ana Maria Vlădăreanu, Irina Voican, Mihai Dimitriu, Natalia Turcan
RATIONALE: Primary myelofibrosis is encountered with the myeloproliferative diseases and is the least prevalent among women of childbearing age. The prognosis is guided by pancytopenia, leukemic transformation and thrombosis which are the dominant complications. PATIENT CONCERNS: Data regarding protocol management during pregnancy in the context of myelofibrosis are insufficient. Fewer than ten cases have been described until now and half of this cases have resulted in fetal death due to placental infarction during the second and third trimesters...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29145270/study-on-the-adverse-effects-following-chemotherapy-for-breast-cancer-diagnosis-during-pregnancy-the-first-case-report-in-china
#15
Xin Ye, Qi He, Xiaoyun Zhou
RATIONALE: Treatment of breast cancer during pregnancy (BCP) remains a challenge to physicians. Surgery and chemotherapy during pregnancy are widely used for the treatment of BCP. Herein, we reported 3 Chinese patients with BCP who underwent chemotherapy during pregnancy and were followed up for adverse effects. PATIENT CONCERNS: Three female patients (case 1, case 2, and case 3) of 37-, 32-, and 28-year-old with breast masses were enrolled. Case 1 had been pregnant for over 4 months, case 2 over 7 months, and case 3 for 7 months...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29144978/attendance-at-prenatal-care-and-adverse-birth-outcomes-in-china-a-follow-up-study-based-on-maternal-and-newborn-s-health-monitoring-system
#16
Aiqun Huang, Keye Wu, Wei Zhao, Huanqing Hu, Qi Yang, Dafang Chen
OBJECTIVE: to evaluate the independent association between attendance at prenatal care and adverse birth outcomes in China, measured either as the occurrence of preterm birth or low birth weight. DESIGN: a follow-up study. SETTING: the data was collected from maternal and newborn's health monitoring system at 6 provinces in China. PARTICIPANTS: all pregnant women registered in the system at their first prenatal care visit...
November 13, 2017: Midwifery
https://www.readbyqxmd.com/read/29144243/risk-of-mortality-into-adulthood-according-to-gestational-age-at-birth
#17
Ravisha Srinivasjois, Wendy Nembhard, Kingsley Wong, Jenny Bourke, Gavin Pereira, Helen Leonard
OBJECTIVES: To quantify the independent risks of neonatal (0-28 days), postneonatal (29-364 days), 1- to 5- and 6- to 30-year mortality by gestational age and investigate changes in survival over time in an Australian birth cohort. STUDY DESIGN: Maternal and birth related Western Australian population data (1980-2010) were linked to the state mortality data using a retrospective cohort study design involving 722 399 live-born singletons infants. RESULTS: When compared with 39- to 41-week born infants, the adjusted risk ratio for neonatal mortality was 124...
November 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/29144191/paternal-involvement-and-support-and-risk-of-preterm-birth-findings-from-the-boston-birth-cohort
#18
Pamela J Surkan, Liming Dong, Yuelong Ji, Xiumei Hong, Hongkai Ji, Mary Kimmel, Wan-Yee Tang, Xiaobin Wang
OBJECTIVE: To investigate to what extent paternal involvement and support during pregnancy were associated with preterm (PTB) and small-for-gestational age (SGA) births. METHODS: Using data from the Boston Birth Cohort (n = 7047), multiple logistic regression models were performed to estimate the log odds of either PTB or SGA birth, with paternal involvement, paternal social support, and family and friend social support variables as the primary independent variables...
November 16, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29143635/a-systematic-review-of-concepts-related-to-women-s-empowerment-in-the-perinatal-period-and-their-associations-with-perinatal-depressive-symptoms-and-premature-birth
#19
Esmeralda R Garcia, Ilona S Yim
BACKGROUND: The perinatal period, which we here define as pregnancy and the first year postpartum, is a time in women's lives that involves significant physiological and psychosocial change and adjustment, including changes in their social status and decision-making power. Supporting women's empowerment at this particular time in their lives may be an attractive opportunity to create benefits for maternal and infant health outcomes such as reductions in perinatal depressive symptoms and premature birth rates...
November 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29143627/conceptualizing-pathways-linking-women-s-empowerment-and-prematurity-in-developing-countries
#20
Patience A Afulani, Molly Altman, Joseph Musana, May Sudhinaraset
BACKGROUND: Globally, prematurity is the leading cause of death in children under the age of 5. Many efforts have focused on clinical approaches to improve the survival of premature babies. There is a need, however, to explore psychosocial, sociocultural, economic, and other factors as potential mechanisms to reduce the burden of prematurity. Women's empowerment may be a catalyst for moving the needle in this direction. The goal of this paper is to examine links between women's empowerment and prematurity in developing settings...
November 8, 2017: BMC Pregnancy and Childbirth
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