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https://www.readbyqxmd.com/read/27873194/lupin-and-other-potentially-cross-reactive-allergens-in-peanut-allergy
#1
REVIEW
Maurizio Mennini, Lamia Dahdah, Oscar Mazzina, Alessandro Fiocchi
PURPOSE OF REVIEW: The presence of IgE cross-reactivity between peanut allergens and allergens from other legumes and tree nuts has been demonstrated, but the identification of the involved individual allergens is still limited. The aim of this review is to describe new allergenic findings, of potential relevance for cross-reactivity among peanut and lupin. RECENT FINDINGS: Seventeen allergens of peanut have been included in the official allergen nomenclature database to date...
November 2016: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/27868253/the-effect-of-lupinus-albus-seeds-on-digestibility-performance-and-gastrointestinal-tract-indices-in-pigs
#2
M Kasprowicz-Potocka, A Zaworska, S Kaczmarek, M Hejdysz, R Mikuła, A Rutkowski
The effect of soya bean meal (SBM) substitution in the diet with white lupine (WL) seeds on performances and some parameters of the digestive tract of pigs were studied. The digestibility experiment was performed on 30 pigs using difference method combined with marker method, where one group was offered basal diet and in diet of experimental groups 25% of the basal diet was substituted with SBM or WL meal. The growth experiment was conducted on 48 pigs of approximately 20 kg body weight. The animals from the control group were fed with diet containing SBM, whereas in the experimental groups 50% or 100% of SBM was substituted with WL seeds...
November 21, 2016: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/27862368/effects-of-heat-treatment-on-protein-feeds-evaluated-in%C3%A2-vitro-by-the-method-of-estimating-utilisable-crude-protein-at-the-duodenum
#3
M Vaga, M Hetta, P Huhtanen
The effect of heat treatment on the protein value of field beans, lupins and peas was studied using an in vitro method. Protein feeds were subjected to heat treatment for 30, 60 and 90 min in forced air oven at 120, 140 and 160 °C and in autoclave at 105, 120 and 135 °C. The heat-treated protein feeds were incubated in buffered rumen fluid together with grass silage and barley in complete isonitrogenous diets. The gas production (GP) was recorded continuously, and ammonia-N (NH3 -N) concentrations were determined during the in vitro incubation at 8, 24 and 48 h and used to determine the utilisable crude protein (uCP) at the duodenum at 16 h of incubation (uCP16 )...
November 11, 2016: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/27858027/%C3%AE-galactosides-present-in-lupin-flour-affect-several-metabolic-parameters-in-wistar-rats
#4
María I Palacio, Adriana R Weisstaub, Ángela Zuleta, Analía I Etcheverría, Guillermo D Manrique
The aim of this study is to evaluate the influence of α-galactosides present in a lupin diet on metabolic parameters in growing Wistar rats. Lupin (Lupinus albus) is a rich source of non-digestible carbohydrates called α-galactosides whose beneficial health effects have been widely reported. For our investigation, twenty male Wistar rats were fed with two different diets: control (C) and lupin flour (L) for a 60-day period. The fermentation of these α-galactosides was monitored by measuring the following indicators: changes in the dynamic lactobacilli and enterobacteriaceae population, cecal content pH, generation of short chain fatty acids (SCFA), Ca and P absorption, and serum lipid (triglycerides and cholesterol) contents...
November 18, 2016: Food & Function
https://www.readbyqxmd.com/read/27810789/multiple-molecular-targets-in-breast-cancer-therapy-by-betulinic-acid
#5
REVIEW
Runlan Luo, Dengyang Fang, Peng Chu, Huajui Wu, Zhuo Zhang, Zeyao Tang
Breast cancer is the second most common type of cancer in the world, and is by far the most prevalent form of cancer in women. However, the efficacy of current treatments for breast cancer is limited. In addition to the high risk of recurrence, some of these have side effects that significantly reduce the quality of life. Therefore, new avenues of treatment for breast cancer are needed. Betulinic acid (BA), a pipeline anticancer drug, exerts anti-proliferative effects on breast cancer cells is mainly through inhibition of cyclin and topoisomerase expression, leading to cell cycle arrest...
October 29, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27769166/expansion-of-the-phosphatidylethanolamine-binding-protein-family-in-legumes-a-case-study-of-lupinus-angustifolius-l-flowering-locus-t-homologs-lanftc1-and-lanftc2
#6
Michał Książkiewicz, Sandra Rychel, Matthew N Nelson, Katarzyna Wyrwa, Barbara Naganowska, Bogdan Wolko
BACKGROUND: The Arabidopsis FLOWERING LOCUS T (FT) gene, a member of the phosphatidylethanolamine binding protein (PEBP) family, is a major controller of flowering in response to photoperiod, vernalization and light quality. In legumes, FT evolved into three, functionally diversified clades, FTa, FTb and FTc. A milestone achievement in narrow-leafed lupin (Lupinus angustifolius L.) domestication was the loss of vernalization responsiveness at the Ku locus. Recently, one of two existing L...
October 21, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27766362/ultrasensitive-and-rapid-detection-of-%C3%AE-conglutin-combining-aptamers-and-isothermal-recombinase-polymerase-amplification
#7
Miriam Jauset-Rubio, Jonathan Sabaté Del Río, Teresa Mairal, Markéta Svobodová, Mohammad S El-Shahawi, Abdulaziz S Bashammakh, Abdulrahman O Alyoubi, Ciara K O'Sullivan
Lupin is increasingly being used in a variety of food products due to its nutritional, functional and nutraceutical properties. However, several examples of severe and even fatal food-associated anaphylaxis due to lupin inhalation or ingestion have been reported, resulting in the lupin subunit β-conglutin, being defined as the Lup an 1 allergen by the International Union of Immunological Societies (IUIS) in 2008. Here, we report an innovative method termed aptamer-recombinase polymerase amplification (Apta-RPA) exploiting the affinity and specificity of a DNA aptamer selected against the anaphylactic β-conglutin allergen termed β-conglutin binding aptamer II (β-CBA II), facilitating ultrasensitive detection via isothermal amplification...
October 20, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27738346/autocrine-interleukin-23-promotes-self-renewal-of-cd133-ovarian-cancer-stem-like-cells
#8
Dan Wang, Tong Xiang, Zhongquan Zhao, Kailong Lin, Pin Yin, Lupin Jiang, Zhiqing Liang, Bo Zhu
Cancer stem cells (CSCs) are a group of cells which possess the ability of self-renewing and unlimited proliferation. And these CSCs are thought to be the cause of metastasis, recurrence and resistance. Recent study has found that pro-inflammatory cytokine and chemotactic factor mediate the self-renewing and differentiation of most of CSCs. Thus we speculate that ovarian cancer stem cells (OCSCs) can also maintain the ability of self-renewing and differentiation by releasing inflammatory factor. This report we discuss the biological characteristics and the specific molecular mechanism mediated by interleukin-23 (IL-23) and its receptor on the self-renewing of OCSCs...
October 12, 2016: Oncotarget
https://www.readbyqxmd.com/read/27706815/influence-of-the-isolation-method-on-the-technofunctional-properties-of-protein-isolates-from-lupinus-angustifolius-l
#9
Isabel S Muranyi, Clemens Otto, Claudia Pickardt, Raffael Osen, Peter Koehler, Ute Schweiggert-Weisz
The technofunctional properties of 2 protein isolates from Lupinus angustifolius L. Vitabor isolated by different procedures were investigated. The lupin protein isolate prepared by aqueous alkaline extraction with subsequent isoelectric precipitation (ILP) showed a significantly higher degree of protein denaturation and lower denaturation temperatures than the one obtained by aqueous salt-induced extraction followed by dilutive precipitation (MLP) as determined by differential scanning calorimetry. Rheological investigations revealed higher firmness and a viscoelastic solid-like behavior of ILP, in contrast to MLP that showed viscoelastic, liquid-like properties...
October 5, 2016: Journal of Food Science
https://www.readbyqxmd.com/read/27688257/cranes-and-crops-investigating-farmer-tolerances-toward-crop-damage-by-threatened-blue-cranes-anthropoides-paradiseus-in-the-western-cape-south-africa
#10
Julia L van Velden, Tanya Smith, Peter G Ryan
The Western Cape population of Blue Cranes (Anthropoides paradiseus) in South Africa is of great importance as the largest population throughout its range. However, Blue Cranes are strongly associated with agricultural lands in the Western Cape, and therefore may come into conflict with farmers who perceive them as damaging to crops. We investigated the viability of this population by exploring farmer attitudes toward crane damage in two regions of the Western Cape, the Swartland and Overberg, using semi-structured interviews...
September 29, 2016: Environmental Management
https://www.readbyqxmd.com/read/27658402/edta-and-hydrochloric-acid-effects-on-mercury-accumulation-by-lupinus-albus
#11
Luis Rodríguez, Jacinto Alonso-Azcárate, José Villaseñor, Laura Rodríguez-Castellanos
The efficiency of white lupine (Lupinus albus) to uptake and accumulate mercury from a soil polluted by mining activities was assessed in a pot experiment with chemically assisted phytoextraction. The mobilizing agents tested were ethylenediaminetetracetic acid (EDTA) and hydrochloric acid (HCl). Two doses of each amendment were used (0.5 and 1.0 g of amendment per kg of soil), and unamended pots were used as a control. Addition of HCl to the soil did not negatively affect plant biomass, while the use of EDTA led to a significant decrease in plant growth when compared to that found for non-treated pots, with plants visually showing symptoms of toxicity...
September 22, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27638916/lost-crops-of-the-incas-origins-of-domestication-of-the-andean-pulse-crop-tarwi-lupinus-mutabilis
#12
Guy W Atchison, Bruno Nevado, Ruth J Eastwood, Natalia Contreras-Ortiz, Carlos Reynel, Santiago Madriñán, Dmitry A Filatov, Colin E Hughes
PREMISE OF THE STUDY: The Andean highlands are a hotspot of domestication, yet our understanding of the origins of early Andean agriculture remains fragmentary. Key questions of where, when, how many times, and from what progenitors many Andean crops were domesticated remain unanswered. The Andean lupine crop tarwi (Lupinus mutabilis) is a regionally important pulse crop with exceptionally high seed protein and oil content and is the focus of modern breeding efforts, but its origins remain obscure...
September 2016: American Journal of Botany
https://www.readbyqxmd.com/read/27557478/a-comprehensive-draft-genome-sequence-for-lupin-lupinus-angustifolius-an-emerging-health-food-insights-into-plant-microbe-interactions-and-legume-evolution
#13
James K Hane, Yao Ming, Lars G Kamphuis, Matthew N Nelson, Gagan Garg, Craig A Atkins, Philipp E Bayer, Armando Bravo, Scott Bringans, Steven Cannon, David Edwards, Rhonda Foley, Ling-Ling Gao, Maria J Harrison, Wei Huang, Bhavna Hurgobin, Sean Li, Cheng-Wu Liu, Annette McGrath, Grant Morahan, Jeremy Murray, James Weller, Jianbo Jian, Karam B Singh
Lupins are important grain legume crops that form a critical part of sustainable farming systems, reducing fertilizer use and providing disease breaks. It has a basal phylogenetic position relative to other crop and model legumes and a high speciation rate. Narrow-leafed lupin (NLL; Lupinus angustifolius L.) is gaining popularity as a health food, which is high in protein and dietary fibre but low in starch and gluten-free. We report the draft genome assembly (609 Mb) of NLL cultivar Tanjil, which has captured > 98% of the gene content, sequences of additional lines and a dense genetic map...
August 24, 2016: Plant Biotechnology Journal
https://www.readbyqxmd.com/read/27542465/european-marketable-grain-legume-seeds-further-insight-into-phenolic-compounds-profiles
#14
Sara C Q Magalhães, Marcos Taveira, Ana R J Cabrita, António J M Fonseca, Patrícia Valentão, Paula B Andrade
Twenty-nine mature raw varieties of grain legume seeds (chickpeas, field peas, faba beans, common vetch and lupins) produced in Europe were investigated for their phenolic profile by means of high performance liquid chromatography coupled to diode array detection (HPLC-DAD). To the best of our knowledge, this study reported for the first time the phenolic composition of mature raw seeds of chickpea type Desi, field pea and common vetch. Phenolic acids were predominant compounds in chickpeas, field peas and common vetch compared to flavonoids, whereas the opposite was observed for lupin seeds...
January 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27539602/estimation-of-the-hydraulic-conductivities-of-lupine-roots-by-inverse-modelling-of-high-resolution-measurements-of-root-water-uptake
#15
Mohsen Zarebanadkouki, Félicien Meunier, Valentin Couvreur, Jimenez Cesar, Mathieu Javaux, Andrea Carminati
BACKGROUND AND AIMS: Radial and axial hydraulic conductivities are key parameters for proper understanding and modelling of root water uptake. Despite their importance, there is limited experimental information on how the radial and axial hydraulic conductivities vary along roots growing in soil. Here, a new approach was introduced to estimate inversely the profile of hydraulic conductivities along the roots of transpiring plants growing in soil. METHODS: A three-dimensional model of root water uptake was used to reproduce the measured profile of root water uptake along roots of lupine plant grown in soil...
August 18, 2016: Annals of Botany
https://www.readbyqxmd.com/read/27539588/messages-from-the-other-side-parasites-receive-damage-cues-from-their-host-plants
#16
Muvari Connie Tjiurutue, Philip C Stevenson, Lynn S Adler
As sessile organisms, plants rely on their environment for cues indicating imminent herbivory. These cues can originate from tissues on the same plant or from different individuals. Since parasitic plants form vascular connections with their host, parasites have the potential to receive cues from hosts that allow them to adjust defenses against future herbivory. However, the role of plant communication between hosts and parasites for herbivore defense remains poorly investigated. Here, we examined the effects of damage to lupine hosts (Lupinus texensis) on responses of the attached hemiparasite (Castilleja indivisa), and indirectly, on a specialist herbivore of the parasite, buckeyes (Junonia coenia)...
August 2016: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/27519912/the-effects-of-nitrogen-form-on-root-morphological-and-physiological-adaptations-of-maize-white-lupin-and-faba-bean-under-phosphorus-deficiency
#17
Haitao Liu, Caixian Tang, Chunjian Li
Root morphological/physiological modifications are important for phosphorus (P) acquisition of plants under P deficiency, but strategies differ among plant species. Detailed studies on the response of maize roots to P deficiency are limited. Nitrogen (N) form influences root morphology/physiology, and thus may influence root responses to P deficiency. This work investigated adaptive mechanisms of maize roots to low P by comparison with white lupin and faba bean supplied with two N forms. Plants were grown for 7-16 days in hydroponics with sufficient (250 µmol L(-1)) and deficient P supply (1 µmol L(-1)) under supply of NH4NO3 or Ca(NO3)2 Plant growth and P uptake were measured, and release of protons and organic acid anions, and acid phosphatase activity in the root were monitored...
2016: AoB Plants
https://www.readbyqxmd.com/read/27516770/a-first-glimpse-of-wild-lupin-karyotype-variation-as-revealed-by-comparative-cytogenetic-mapping
#18
Karolina Susek, Wojciech K Bielski, Robert Hasterok, Barbara Naganowska, Bogdan Wolko
Insight into plant genomes at the cytomolecular level provides useful information about their karyotype structure, enabling inferences about taxonomic relationships and evolutionary origins. The Old World lupins (OWL) demonstrate a high level of genomic diversification involving variation in chromosome numbers (2n = 32-52), basic chromosome numbers (x = 5-7, 9, 13) and in nuclear genome size (2C DNA = 0.97-2.68 pg). Lupins comprise both crop and wild species and provide an intriguing system to study karyotype evolution...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27498896/widespread-adaptive-evolution-during-repeated-evolutionary-radiations-in-new-world-lupins
#19
Bruno Nevado, Guy W Atchison, Colin E Hughes, Dmitry A Filatov
The evolutionary processes that drive rapid species diversification are poorly understood. In particular, it is unclear whether Darwinian adaptation or non-adaptive processes are the primary drivers of explosive species diversifications. Here we show that repeated rapid radiations within New World lupins (Lupinus, Leguminosae) were underpinned by a major increase in the frequency of adaptation acting on coding and regulatory changes genome-wide. This contrasts with far less frequent adaptation in genomes of slowly diversifying lupins and all other plant genera analysed...
2016: Nature Communications
https://www.readbyqxmd.com/read/27492575/place-making-with-older-persons-establishing-sense-of-place-through-participatory-community-mapping-workshops
#20
Mei Lan Fang, Ryan Woolrych, Judith Sixsmith, Sarah Canham, Lupin Battersby, Andrew Sixsmith
Principles of aging-in-place emphasize the importance of creating sustainable environments that enable older people to maintain a sense of belonging, autonomy, independence, safety and security. Simply altering the built environment is insufficient for creating more inclusive environments for older persons, as creating 'meaningful' places for aging involves consideration of psychosocial and cultural issues that go beyond issues of physical space. This paper illustrates how applications of community-based participatory research methods, in particular, participatory community mapping workshops (PCMWs), can be used to access experiences of place, identify facilitators and barriers to accessing the built environment and co-create place-based solutions among older people and service providers in a new affordable housing development in Western Canada...
November 2016: Social Science & Medicine
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