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https://www.readbyqxmd.com/read/28207840/using-the-hephaistos-orthotic-device-to-study-countermeasure-effectiveness-of-neuromuscular-electrical-stimulation-and-dietary-lupin-protein-supplementation-a-randomised-controlled-trial
#1
Jochen Zange, Kathrin Schopen, Kirsten Albracht, Darius A Gerlach, Petra Frings-Meuthen, Nicola A Maffiuletti, Wilhelm Bloch, Jörn Rittweger
PURPOSE: The present study investigated whether neuromuscular electrical stimulation for 20 min twice a day with an electrode placed over the soleus muscle and nutritional supplementation with 19 g of protein rich lupin seeds can reduce the loss in volume and strength of the human calf musculature during long term unloading by wearing an orthotic unloading device. METHODS: Thirteen healthy male subjects (age of 26.4 ± 3.7 years) wore a Hephaistos orthosis one leg for 60 days during all habitual activities...
2017: PloS One
https://www.readbyqxmd.com/read/28203647/the-potential-of-blue-lupins-as-a-protein-source-in-the-diets-of-laying-hens
#2
Michael R F Lee, Sarah Parkinson, Hannah R Fleming, Vince J Theobald, Dave K Leemans, Tony Burgess
Layers diets typically contain 15-20% soya due to its high crude protein content (ca. 36%). Reliance on soya for protein can result in large increases in cost of feed due to the law of supply and demand as a global commodity. Lupin grains have high protein content (35-40%) but previous experience with white lupins has shown toxic effects in poultry due to high levels alkaloids and poor performance due to anti-nutritional Non-starch polysaccharides (NSP). Here blue lupins either processed or whole were trialled for their potential as a protein source...
December 2016: Veterinary and Animal Science
https://www.readbyqxmd.com/read/28197163/quinolizidine-alkaloid-biosynthesis-in-lupins-and-prospects-for-grain-quality-improvement
#3
REVIEW
Karen M Frick, Lars G Kamphuis, Kadambot H M Siddique, Karam B Singh, Rhonda C Foley
Quinolizidine alkaloids (QAs) are toxic secondary metabolites found within the genus Lupinus, some species of which are commercially important grain legume crops including Lupinus angustifolius (narrow-leafed lupin, NLL), L. luteus (yellow lupin), L. albus (white lupin), and L. mutabilis (pearl lupin), with NLL grain being the most largely produced of the four species in Australia and worldwide. While QAs offer the plants protection against insect pests, the accumulation of QAs in lupin grain complicates its use for food purposes as QA levels must remain below the industry threshold (0...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28194675/effect-of-soil-contamination-with-fluorine-on-the-yield-and-content-of-nitrogen-forms-in-the-biomass-of-crops
#4
Radosław Szostek, Zdzisław Ciećko
The research was based on a pot experiment, in which the response of eight species of crops to soil contamination with fluorine was investigated. In parallel, some inactivating substances were tested in terms of their potential use for the neutralization of the harmful influence of fluorine on plants. The response of crops to soil contamination with fluorine was assessed according to the volume of biomass produced by aerial organs and roots as well as their content of N-total, N-protein, and N-NO3(-). The following crops were tested: maize, yellow lupine, winter oilseed rape, spring triticale, narrow-leaf lupine, black radish, phacelia, and lucerne...
February 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28183653/synthesis-characterization-and-augmented-anticancer-potential-of-peg-betulinic-acid-conjugate
#5
Ankit Saneja, Love Sharma, Ravindra Dhar Dubey, Mubashir Javed Mintoo, Amrinder Singh, Amit Kumar, Payare Lal Sangwan, Sheikh Abdullah Tasaduq, Gurdarshan Singh, Dilip M Mondhe, Prem N Gupta
Betulinic acid (BA), a pentacyclic lupine-type triterpene, is reported to inhibit cell growth in a variety of cancers. However, its efficacy is limited by its poor aqueous solubility and relatively short half-life. In this study, BA-monomethoxy polyethylene glycol (mPEG) conjugate was synthesized by covalent coupling the C-28 carboxylic acid position of BA with amine groups of mPEG, in order to improve its solubility and anticancer efficacy. mPEG-BA conjugate was characterized using various analytical techniques including NMR, FT-IR and MALDI-MS...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28165413/potential-uses-of-wild-germplasms-of-grain-legumes-for-crop-improvement
#6
REVIEW
Nacira Muñoz, Ailin Liu, Leo Kan, Man-Wah Li, Hon-Ming Lam
Challenged by population increase, climatic change, and soil deterioration, crop improvement is always a priority in securing food supplies. Although the production of grain legumes is in general lower than that of cereals, the nutritional value of grain legumes make them important components of food security. Nevertheless, limited by severe genetic bottlenecks during domestication and human selection, grain legumes, like other crops, have suffered from a loss of genetic diversity which is essential for providing genetic materials for crop improvement programs...
February 4, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28133984/new-arylsparteine-derivatives-as-positive-inotropic-drugs
#7
Vito Boido, Marcella Ercoli, Michele Tonelli, Federica Novelli, Bruno Tasso, Fabio Sparatore, Elena Cichero, Paola Fossa, Paola Dorigo, Guglielmina Froldi
Positive inotropic agents are fundamental in the treatment of heart failure; however, their arrhythmogenic liability and the increased myocardial oxygen demand strongly limit their therapeutic utility. Pursuing our study on cardiovascular activities of lupin alkaloid derivatives, several 2-(4-substituted-phenyl)-2-dehydrosparteines and 2-(4-substituted-phenyl)sparteines were prepared and tested for inotropic and chronotropic activities on isolated guinea pig atria. Four compounds (6b, 6e, 7b, and 7f) exhibited significant inotropism that, at the higher concentrations, was followed by negative inotropism or toxicity...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28133815/comparison-of-nutritional-and-antinutritional-traits-among-different-species-lupinus-albus-l-lupinus-luteus-l-lupinus-angustifolius-l-and-varieties-of-lupin-seeds
#8
N Musco, M I Cutrignelli, S Calabrò, R Tudisco, F Infascelli, R Grazioli, V Lo Presti, F Gresta, B Chiofalo
In order to promote the use of lupin in pig nutrition, in this research the nutritional characteristics (i.e. dietary fibre, alkaloid and fatty acid profile) and the in vitro gas production of 12 lupin varieties grown in the Mediterranean basin and belonging to three lupin species (Lupinus albus, Lupinus angustifolius and Lupinus luteus) were assessed. Four varieties of L. albus (Asfer, Lublanc, Lutteur and Multitalia) were grown in South Campania. Three varieties of L. luteus (Dukat, Mister and Taper), three of L...
January 30, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28122929/a-systematic-review-of-the-effects-of-plant-compared-with-animal-protein-sources-on-features-of-metabolic-syndrome
#9
REVIEW
Tristan Chalvon-Demersay, Dalila Azzout-Marniche, Judith Arfsten, Léonie Egli, Claire Gaudichon, Leonidas G Karagounis, Daniel Tomé
Dietary protein may play an important role in the prevention of metabolic dysfunctions. However, the way in which the protein source affects these dysfunctions has not been clearly established. The aim of the current systematic review was to compare the impact of plant- and animal-sourced dietary proteins on several features of metabolic syndrome in humans. The PubMed database was searched for both chronic and acute interventional studies, as well as observational studies, in healthy humans or those with metabolic dysfunctions, in which the impact of animal and plant protein intake was compared while using the following variables: cholesterolemia and triglyceridemia, blood pressure, glucose homeostasis, and body composition...
January 25, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28115754/amino-acids-profile-and-antioxidant-activity-of-different-lupinus-angustifolius-seeds-after-solid-state-and-submerged-fermentations
#10
Vytaute Starkute, Elena Bartkiene, Vadims Bartkevics, Janis Rusko, Daiva Zadeike, Grazina Juodeikiene
The objective of this study was to investigate the amino acids profile, total phenolic compounds (TPC) content, antioxidant activity after submerged (SmF) and solid state (SSF) fermentations of different Lupinus angustifolius seeds by the Lactobacillus sakei KTU05-6. Additionally, the impact of different lupin seeds as fermentation media for LAB biomass and d/l-lactic acid production was analysed. The d/l ratio for SmF and SSF treated lupin samples varied from 0.15 to 0.45 and from 0.12 to 0.46, 16 respectively...
December 2016: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28071032/legume-seeds-and-cereal-grains-capacity-to-accumulate-iron-while-sprouting-in-order-to-obtain-food-fortificant
#11
Magdalena Zielińska-Dawidziak, Halina Staniek, Ewelina Król, Dorota Piasecka-Kwiatkowska, Tomasz Twardowski
BACKGROUND: Prepared sprouts, after culturing in a medium with an increased iron concentration, could become a beneficial food iron fortificant. However, the efficient iron accumulation depends on the plants genus, species and/or varieties. The aim of the study was to indicate the seeds or grains which accumulate iron most efficiently during the sprouting process. METHODS: Alfalfa, lentil, lupine and soybean seeds as well as wheat grains were sprouted in abiotic stress conditions induced by the excess of iron(II) in culture media...
July 2016: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/28062461/diverse-bacteria-affiliated-with-the-genera-microvirga-phyllobacterium-and-bradyrhizobium-nodulate-lupinus-micranthus-growing-in-soils-of-northern-tunisia
#12
Abdelhakim Msaddak, David Durán, Mokhtar Rejili, Mohamed Mars, Tomás Ruiz-Argüeso, Juan Imperial, José Palacios, Luis Rey
: The genetic diversity of bacterial populations nodulating Lupinus micranthus in five geographical sites from Northern Tunisia was examined. Phylogenetic analyses of fifty isolates based on recA and gyrB gene partial sequences grouped strains in seven clusters, five of which belong to genus Bradyrhizobium (28 isolates), one to Phyllobacterium (2 isolates), and one, remarkably, to Microvirga (20 isolates). The largest Bradyrhizobium cluster (17 isolates) grouped with the B. lupini species and the other five clusters were close to different, recently defined Bradyrhizobium species...
January 6, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28018392/narrow-leafed-lupin-lupinus-angustifolius-%C3%AE-1-and-%C3%AE-6-conglutin-proteins-exhibit-antifungal-activity-protecting-plants-against-necrotrophic-pathogen-induced-damage-from-sclerotinia-sclerotiorum-and-phytophthora-nicotianae
#13
Jose C Jimenez-Lopez, Su Melser, Kathleen DeBoer, Louise F Thatcher, Lars G Kamphuis, Rhonda C Foley, Karam B Singh
Vicilins (7S globulins) are seed storage proteins and constitute the main protein family in legume seeds, particularly in narrow-leafed lupin (Lupinus angustifolius L.; NLL), where seven vicilin genes, called β1- to β7-conglutin have been identified. Vicilins are involved in germination processes supplying amino acids for seedling growth and plant development, as well as in some cases roles in plant defense and protection against pathogens. The roles of NLL β-conglutins in plant defense are unknown. Here the potential role of five NLL β-conglutin family members in protection against necrotrophic fungal pathogens was investigated and it was demonstrated that recombinant purified 6xHis-tagged β1- and β6-conglutin proteins exhibited the strongest in vitro growth inhibitory activity against a range of necrotrophic fungal pathogens compared to β2, β3, and β4 conglutins...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28013171/asparagine-slows-down-the-breakdown-of-storage-lipid-and-degradation-of-autophagic-bodies-in-sugar-starved-embryo-axes-of-germinating-lupin-seeds
#14
Sławomir Borek, Ewelina Paluch-Lubawa, Stanisława Pukacka, Małgorzata Pietrowska-Borek, Lech Ratajczak
The research was conducted on embryo axes of yellow lupin (Lupinus luteus L.), white lupin (Lupinus albus L.) and Andean lupin (Lupinus mutabilis Sweet), which were isolated from imbibed seeds and cultured for 96h in vitro under different conditions of carbon and nitrogen nutrition. Isolated embryo axes were fed with 60mM sucrose or were sugar-starved. The effect of 35mM asparagine (a central amino acid in the metabolism of germinating lupin seeds) and 35mM nitrate (used as an inorganic kind of nitrogen) on growth, storage lipid breakdown and autophagy was investigated...
December 10, 2016: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28012244/%C3%AE-arrow-leafed-lupin-lupinus-angustifolius-l-%C3%AE-conglutin-proteins-modulate-the-insulin-signalling-pathway-as-potential-type-2-diabetes-treatment-and-inflammatory-related-disease-amelioration
#15
Elena Lima-Cabello, Victor Alche, Rhonda C Foley, Sofianos Andrikopoulos, Grant Morahan, Karam B Singh, Juan D Alche, Jose C Jimenez-Lopez
SCOPE: We have investigated the potential use of β-conglutin protein isoforms from narrow-leafed lupin (Lupinus angustifolius L.) as a diabetes treatment. METHODS AND RESULTS: We produced purified recombinant β1-, β2-, β3-, β4-, and β6-conglutin proteins and showed that β1, β3 and β6 could bind to insulin. To assess β-conglutin proteins modulatory effect on insulin-activation meditated kinases, whole blood and peripheral blood mononuclear cell (PBMC) cultures from Type 2 diabetes (T2D) and healthy control subjects (C) were incubated with conglutin proteins...
December 24, 2016: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/27983830/peptides-derived-from-soy-and-lupin-protein-as-dipeptidyl-peptidase-iv-inhibitors-in-vitro-biochemical-screening-and-in-silico-molecular-modeling-study
#16
Carmen Lammi, Chiara Zanoni, Anna Arnoldi, Giulio Vistoli
Dipeptidyl peptidase IV (DPP-IV) is a new molecular target correlated with the development of type 2 diabetes. Literature describes the identification of some inhibitory peptides from the hydrolysis of different food proteins. This article reports a study on six peptides from soybean and lupin proteins, i.e., Soy 1 (IAVPTGVA), Soy 2 (YVVNPDNDEN), Soy 3 (YVVNPDNNEN), Lup 1 (LTFPGSAED), Lup 2 (LILPKHSDAD), and Lup 3 (GQEQSHQDEGVIVR), which were screened for their capacity to inhibit the activity of DPP-IV, using an in vitro bioassay against human recombinant DPP-IV...
December 28, 2016: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/27976189/characterization-of-anthelminthic-properties-of-the-lupine-seed-lupinus-spp
#17
O Dubois, G Sallé, H Février, J B Magnin-Robert, N Harzic, C Charvet, C Neveu, C Enguehard-Gueiffer, L Boudesocque-Delaye
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27975437/transcriptome-sequencing-in-narrow-leafed-lupin-lupinus-angustifolius-combining-short-and-long-read-sequencing-platforms
#18
T Yang, I Nagy, T Asp, F Geu-Flores
No abstract text is available yet for this article.
December 2016: Planta Medica
https://www.readbyqxmd.com/read/27956868/the-effect-of-dry-yeast-fermentation-on-chemical-composition-and-protein-characteristics-of-blue-lupin-seeds
#19
Małgorzata Kasprowicz-Potocka, Paulina Borowczyk, Anita Zaworska, Włodzimierz Nowak, Andrzej Frankiewicz, Piotr Gulewicz
The effect of 24-hour fermentation of lupin seeds by different yeast strains on their chemical composition was determined. After fermentation, the mass fraction of proteins increased and their in vitro digestibility and biological activity significantly improved. The amino acid profile of fermented products was similar to that of raw lupin seeds. The significant reduction in the mass fraction of oligosaccharides and phytate, but not of alkaloids was found. The pH level of fermented products decreased as a consequence of the increase of lactic and propionic acid mass fractions...
September 2016: Food Technology and Biotechnology
https://www.readbyqxmd.com/read/27916928/the-effect-of-lupinus-albus-and-calcium-chloride-on-growth-performance-body-composition-plasma-biochemistry-and-meat-quality-of-male-pigs-immunized-against-gonadotrophin-releasing-factor
#20
Karen Moore, Bruce Mullan, Jae Cheol Kim, Frank Dunshea
Two hundred and ninety-four pigs were used to assess the effect of two ingredients (Lupinus albus (albus lupins) or a combination of calcium chloride and sodium tri-polyphosphate (mineral salts)) on growth performance, body composition and objective meat quality of pigs immunized against gonadotrophin releasing factor (immunocastrates) and entire male pigs in the late finishing phase. Pigs fed mineral salts ate less feed than those fed the control diet with no effect on growth rate (p > 0.05), backfat (p > 0...
December 1, 2016: Animals: An Open Access Journal From MDPI
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