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https://www.readbyqxmd.com/read/29351273/understanding-the-legal-trade-of-cattle-and-camels-and-the-derived-risk-of-rift-valley-fever-introduction-into-and-transmission-within-egypt
#1
Sebastian Napp, Veronique Chevalier, Núria Busquets, Paolo Calistri, Jordi Casal, Mohamed Attia, Rehab Elbassal, Heba Hosni, Hatem Farrag, Noura Hassan, Rasha Tawfik, Sohair Abd Elkader, Shahin Bayomy
Rift Valley Fever (RVF) is a mosquito-borne zoonosis, which may cause significant losses for the livestock sector and have serious public health implications. Egypt has been repeatedly affected by RVF epidemics, mainly associated to the importation of animals from sub-Saharan countries, where the disease is endemic. The objective of our study was the improvement of the surveillance and control strategies implemented in Egypt. In order to do that, first we evaluated the legal trade of live animals into and within Egypt...
January 19, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29345302/body-mass-prediction-from-femoral-volume-and-sixteen-other-femoral-variables-in-the-elderly-bmi-and-adipose-tissue-effects
#2
Tony Chevalier, Jan Pieter Clarys, Philippe Lefèvre, Jean-Pol Beauthier, Stéphane Louryan, Erik Cattrysse
OBJECTIVES: The frequently used prediction equations of body mass do not seem appropriate for elderly individuals. Here, we establish the relationship between femoral dimensions and known body mass in elderly individuals in order to develop prediction formulas and identify the factors affecting their accuracy. MATERIALS AND METHODS: The body mass linear least-squares regression is based on 17 femoral dimensions, including femoral volume, and 66 individuals. Body proportion and composition effects on accuracy are analyzed by means of the body mass index (BMI) and on a subset sample (n = 25), by means of the masses of adipose, bone and muscle tissues...
January 18, 2018: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/29343513/using-genetic-buffering-relationships-identified-in-fission-yeast-to-reveal-susceptibilities-in-cells-lacking-hamartin-or-tuberin-function
#3
Ashyad Rayhan, Adam Faller, Ryan Chevalier, Alannah Mattice, Jim Karagiannis
Tuberous sclerosis complex is an autosomal dominant disorder characterized by benign tumors arising from the abnormal activation of mTOR signaling in cells lacking TSC1 (hamartin) or TSC2 (tuberin) activity. To expand the genetic framework surrounding this group of growth regulators, we utilized the model eukaryote Schizosaccharomyces pombe to uncover and characterize genes that buffer the phenotypic effects of mutations in the orthologous tsc1 or tsc2 loci. Our study identified two genes: fft3 (encoding a DNA helicase) and ypa1 (encoding a peptidyle-prolyl cis/trans isomerase)...
January 17, 2018: Biology Open
https://www.readbyqxmd.com/read/29336820/micro-ct-and-micro-fe-analysis-of-pedicle-screw-fixation-under-different-loading-conditions
#4
Y Chevalier, M Matsuura, S Krüger, C Fleege, M Rickert, M Rauschmann, C Schilling
Anchorage of pedicle screw instrumentation in the elderly spine with poor bone quality remains challenging. In this study, micro finite element (µFE) models were used to assess the specific influence of screw design and the relative contribution of local bone density to fixation mechanics. These were created from micro computer tomography (µCT) scans of vertebras implanted with two types of pedicle screws, including a full region-or-interest of 10 mm radius around each screw, as well as submodels for the pedicle and inner trabecular bone of the vertebral body...
December 26, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29335553/mutations-in-ppe38-block-pe_pgrs-secretion-and-increase-virulence-of-mycobacterium-tuberculosis
#5
Louis S Ates, Anzaan Dippenaar, Roy Ummels, Sander R Piersma, Aniek D van der Woude, Kim van der Kuij, Fabien Le Chevalier, Dulce Mata-Espinosa, Jorge Barrios-Payán, Brenda Marquina-Castillo, Carolina Guapillo, Connie R Jiménez, Arnab Pain, Edith N G Houben, Robin M Warren, Roland Brosch, Rogelio Hernández-Pando, Wilbert Bitter
Mycobacterium tuberculosis requires a large number of secreted and exported proteins for its virulence, immune modulation and nutrient uptake. Most of these proteins are transported by the different type VII secretion systems1,2. The most recently evolved type VII secretion system, ESX-5, secretes dozens of substrates belonging to the PE and PPE families, which are named for conserved proline and glutamic acid residues close to the amino terminus3,4. However, the role of these proteins remains largely elusive 1 ...
January 15, 2018: Nature Microbiology
https://www.readbyqxmd.com/read/29332161/the-computed-tomography-adrenal-wash-out-analysis-properly-classifies-cortisol-secreting-adrenocortical-adenomas
#6
Anne-Laure Humbert, Guillaume Lecoanet, Sophie Moog, Fehd Bouderraoui, Laurent Bresler, Jean-Michel Vignaud, Elodie Chevalier, Laurent Brunaud, Marc Klein, Thomas Cuny
PURPOSE: Adrenocortical lesions are characterized through imaging, hormonal and histopathological analysis. Our aim was to compare the radiological features of adrenocortical lesions with their cortisol-secreting status and histopathological Weiss score. METHODS: Seventy five patients operated between 2004 and 2016 in the University Hospital of Nancy for either adrenocortical carcinomas (ACC) or adrenocortical adenomas (ACA) were enrolled in this study. We collected cortisol parameters, Computed Tomography (CT) scans (unenhanced density, wash-out (WO) analysis) and 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) datas...
January 13, 2018: Endocrine
https://www.readbyqxmd.com/read/29298836/at-mini-zinc-finger2-and-sl-inhibitor-of-meristem-activity-a-conserved-missing-link-in-the-regulation-of-floral-meristem-termination-in-arabidopsis-and-tomato
#7
Norbert Bollier, Adrien Sicard, Julie Leblond-Castaing, David Latrasse, Nathalie Gonzalez, Frédéric Gévaudant, Moussa Benhamed, Cécile Raynaud, Michael Lenhard, Christian Chevalier, Michel Hernould, Frédéric Delmas
In angiosperms, the gynoecium is the last structure to develop within the flower due to the determinate fate of floral meristem (FM) stem cells. The maintenance of stem cell activity before its arrest at the stage called FM termination affects the number of carpels that develop. The necessary inhibition at this stage of WUSCHEL (WUS), which is responsible for stem cell maintenance, involves a two-step mechanism. Direct repression mediated by the MADS-domain transcription factor AGAMOUS (AG), followed by indirect repression requiring the C2H2 zinc-finger protein KNUCKLES (KNU), allow for the complete termination of floral stem cell activity...
January 3, 2018: Plant Cell
https://www.readbyqxmd.com/read/29297176/the-antiarrhythmic-effect-of-vagal-stimulation-after-acute-coronary-occlusion-role-of-the-heart-rate
#8
Waheed Manati, Julien Pineau, Rosa Doñate Puertas, Elodie Morel, Timour Quadiri, Bernard Bui-Xuan, Philippe Chevalier
BACKGROUND: Strong evidence suggests a causal link between autonomic disturbances and ventricular arrhythmias. However, the mechanisms underlying the antiarrhythmic effect of vagal stimulation are poorly understood. The vagal antiarrhythmic effect might be modulated by a decrease in heart rate. METHODS: the proximal anterior interventricular artery was occluded in 16 pigs by clamping under general anaesthesia. Group 1: heart rates remained spontaneous (n = 6; 12 occlusions); Group 2: heart rates were fixed at 190 beats per minute (bpm) with atrial electrical stimulation (n = 10; 20 occlusions)...
January 3, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29296579/early-repolarization-syndrome-caused-by-de-novo-duplication-of-kcnd3-detected-by-next-generation-sequencing
#9
Samuel Chauveau, Alexandre Janin, Marianne Till, Elodie Morel, Philippe Chevalier, Gilles Millat
No abstract text is available yet for this article.
December 2017: HeartRhythm Case Reports
https://www.readbyqxmd.com/read/29277435/assessment-of-potential-heart-donors-a-statement-from-the-french-heart-transplant-community
#10
Richard Dorent, Estelle Gandjbakhch, Céline Goéminne, Fabrice Ivanes, Laurent Sebbag, Fabrice Bauer, Eric Epailly, Pascale Boissonnat, Karine Nubret, Julien Amour, Emmanuelle Vermes, Phalla Ou, Soulef Guendouz, Philippe Chevalier, Guillaume Lebreton, Erwan Flecher, Jean-François Obadia, Damien Logeart, Pascal de Groote
Assessment of potential donors is an essential part of heart transplantation. Despite the shortage of donor hearts, donor heart procurement from brain-dead organ donors remains low in France, which may be explained by the increasing proportion of high-risk donors, as well as the mismatch between donor assessment and the transplant team's expectations. Improving donor and donor heart assessment is essential to improve the low utilization rate of available donor hearts without increasing post-transplant recipient mortality...
December 22, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29274479/sub-surface-assessment-of-hydrothermal-ageing-in-zirconia-containing-femoral-heads-for-hip-joint-applications
#11
L Gremillard, J Chevalier, L Martin, T Douillard, S Begand, K Hans, T Oberbach
Zirconia-based materials have been used in orthopaedics since the 1980s, with large success, mainly thanks to transformation toughening. On the other hand, their main drawback is their potential sensitivity to hydrothermal ageing, i.e. tetragonal to monoclinic phase transformation on their surface in the presence of water. Hydrothermal ageing may result in roughness increase and microcracking of the surface. In this article the hydrothermal ageing behaviour of three medical-grade zirconia-based materials is assessed at high temperature and extrapolated to room or body temperature...
December 20, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29273154/developmental-origins-of-ckd-big-problems-from-small-packages
#12
EDITORIAL
Jennifer R Charlton, Robert L Chevalier
No abstract text is available yet for this article.
January 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29258901/association-between-low-plasma-level-of-citrulline-before-allogeneic-hematopoietic-cell-transplantation-and-severe-gastrointestinal-graft-vs-host-disease
#13
Thomas Hueso, Jordan Gauthier, Marie Joncquel Chevalier-Curt, Leonardo Magro, Valerie Coiteux, Remy Dulery, Benjamin Carpentier, Julien Labreuche, Gandhi Damaj, Ibrahim Yakoub-Agha, David Seguy
BACKGROUND & AIMS: The gastrointestinal form of acute graft vs host disease increases morbidity and mortality following allogeneic hematopoietic cell transplantation. Plasma levels of citrulline, a non-proteinogenic amino acid, indicate functional enterocyte mass. We measured citrulline in patients before allogeneic hematopoietic cell transplantation and investigated its association with incidence and severity of gastrointestinal graft vs host disease. METHODS: We performed a retrospective study with 191 patients (69 women, 122 men; median age of 52 years) who underwent allogeneic hematopoietic cell transplantation for hematological malignancies at a tertiary center of France from January 2013 through April 2015...
December 16, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29246909/serial-assessment-of-strut-coverage-of-biodegradable-polymer-drug-eluting-stent-at-1-2-and-3-months-after-stent-implantation-by-optical-frequency-domain-imaging-the-discovery-1to3-study-evaluation-with-ofdi-of-strut-coverage-of-terumo-new-drug-eluting-stent
#14
Bernard Chevalier, Pieter C Smits, Didier Carrié, Julinda Mehilli, Ad J Van Boven, Evelyn Regar, Fadi J Sawaya, Daniel Chamié, Adriaan O Kraaijeveld, Thomas Hovasse, Georgios J Vlachojannis
BACKGROUND: To assess the vessel-healing pattern of Ultimaster drug-eluting stent using optical frequency domain imaging. Our hypothesis is that biodegradable polymer-based drug-eluting technology allows complete very early strut coverage. METHODS AND RESULTS: The DISCOVERY 1TO3 study (Evaluation With OFDI of Strut Coverage of Terumo New Drug Eluting Stent With Biodegradable Polymer at 1, 2, and 3 Months) is a prospective, single-arm, multicenter study. A total of 60 patients with multivessel disease requiring staged procedure at 1 month were treated with Ultimaster...
December 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29246481/shoulder-patient-specific-guide-first-experience-in-10-patients-indicates-room-for-improvement
#15
J Berhouet, M Rol, C Spiry, M Slimane, C Chevalier, L Favard
BACKGROUND: Implantation of the glenoid component of a total shoulder prosthesis can be facilitated by using a patient-specific guide (PSG) designed to ensure replication of the preoperatively planned position. The objective of this study was to assess the reliability and accuracy of a PSG in replicating the planned glenoid component position during total shoulder arthroplasty (TSA). HYPOTHESIS: Additional criteria should be used for 3D preoperative planning and PSG design to further improve the accuracy of glenoid component positioning...
December 12, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29229215/atrial-fibrillation-neurogenic-or-myogenic
#16
REVIEW
Alina Scridon, Răzvan Constantin Şerban, Philippe Chevalier
A 55-year-old hypertensive patient presents atrial fibrillation after vasovagal syncope. Non-invasive cardiac workup is normal. Without antiarrhythmic therapy, the patient has no recurrence for the next 3years, then presents with a stroke. Echocardiography eventually reveals left atrial dilation. This sequence of events illustrates the well-known links between age, arterial hypertension, atrial fibrillation, atrial neuromyopathy and stroke. A frequently neglected common denominator in this equation is impaired sympathovagal balance...
December 8, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29228383/oral-fungal-bacterial-biofilm-models-in-vitro-a-review
#17
Marlene Chevalier, Stephane Ranque, Isabelle Prêcheur
Inclusion of fungi as commensals in oral biofilm is an important innovation in oral biology, and this work aimed to review the literature on the available biofilm and related disease in vitro models. Actually, thousands of bacterial and around one hundred of fungal phylotypes can colonize the oral cavity. Taxonomic profiling combined with functional expression analysis has revealed that Candida albicans, Streptococcus mutans and prominent periodontopathogens are not always present or numerically important in candidiasis, caries, or periodontitis lesions...
December 8, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29225848/delayed-diagnosis-of-brugada-syndrome-in-a-patient-with-aborted-sudden-cardiac-death-and-initial-negative-flecainide-challenge
#18
Samuel Chauveau, Olivier Le Vavasseur, Philippe Chevalier
A negative flecainide challenge does not rule out Brugada syndrome even in the presence of nonfatal cardiac arrest as the first manifestation of the disease. This should prompt clinicians to ensure long-term ECG follow-up and consider repeating a drug test with another sodium channel blocker.
December 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/29222941/characterization-of-the-spoilage-potential-of-pure-and-mixed-cultures-of-bacterial-species-isolated-from-tropical-yellowfin-tuna-thunnus-albacares
#19
Adèle Silbande, Josiane Cornet, Mireille Cardinal, Frédérique Chevalier, Katia Rochefort, Juliette Smith-Ravin, Sandra Adenet, Françoise Leroi
AIM: The spoilage potential of 28 bacterial strains isolated from spoiled raw yellowfin tuna was evaluated. METHODS AND RESULTS: Bacterial species were inoculated in irradiated tuna matrix. Chemical changes, bacterial growth and sensory quality were monitored during aerobic storage at 8°C. Pseudomonas spp., Enterobacter spp. and Escherichia hermanii had no spoiling effect. Brochothrix thermosphacta and Carnobacterium divergens/maltaromaticum developed moderate unpleasant odors...
December 9, 2017: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29221796/synthesis-and-antibacterial-activity-of-new-peptides-from-alfalfa-rubisco-protein-hydrolysates-and-mode-of-action-via-a-membrane-damage-mechanism-against-listeria-innocua
#20
Sabrine Kobbi, Naima Nedjar, Nourdine Chihib, Rafik Balti, Mickael Chevalier, Amandine Silvain, Semia Chaabouni, Pascal Dhulster, Ali Bougatef
In this work we evaluated the mode of action of six new synthesized peptides (Met-Asp-Asn; Glu-leu-Ala-Ala-Ala-Cys; Leu-Arg-Asp-Asp-Phe; Gly-Asn-Ala-Pro-Gly-Ala-Val-Ala; Ala-Leu-Arg-Met-Ser-Gly and Arg-Asp-Arg-Phe-Leu), previously identified, from the most active peptide fractions of RuBisCO peptic hydrolysate against Listeria innocua via a membrane damage mechanism. Antibacterial effect and the minimum inhibitory concentrations (MIC) of these peptides were evaluated against six strains and their hemolytic activities towards bovine erythrocytes were determined...
December 5, 2017: Microbial Pathogenesis
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