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JOURNAL ARTICLE
Elna Hamilton Larsen, Astrid Klopstad Wahl, Ellen Ruud, Anneli Viktoria Mellblom, Anette Ålykkja, Hanne Cathrine Lie
Background: Transitioning from active cancer treatment to survivorship represents a vulnerable yet underresearched phase for adolescents and their families. Knowledge of their support needs, the challenges they experience, and how they manage them are useful to inform tailored follow-up care. Thus, we aimed to explore their transition experiences. Method: We interviewed 15 adolescents (12-19 years) who had transitioned off of treatment 1 to 47 months prior at Oslo University Hospital's Department of Paediatric Haematology and Oncology and their biological parents ( n = 16)...
April 24, 2024: J Pediatr Hematol Oncol Nurs
#22
JOURNAL ARTICLE
Cynthia Gyamfi-Bannerman, Rebecca G Clifton, Alan T N Tita, Sean C Blackwell, Monica Longo, Jessica A de Voest, T Michael O'Shea, Sabine Z Bousleiman, Felecia Ortiz, Dwight J Rouse, Torri D Metz, George R Saade, Kara M Rood, Kent D Heyborne, John M Thorp, Geeta K Swamy, William A Grobman, Kelly S Gibson, Yasser Y El-Sayed, George A Macones
IMPORTANCE: The Antenatal Late Preterm Steroids (ALPS) trial changed clinical practice in the United States by finding that antenatal betamethasone at 34 to 36 weeks decreased short-term neonatal respiratory morbidity. However, the trial also found increased risk of neonatal hypoglycemia after betamethasone. This follow-up study focused on long-term neurodevelopmental outcomes after late preterm steroids. OBJECTIVE: To evaluate whether administration of late preterm (34-36 completed weeks) corticosteroids affected childhood neurodevelopmental outcomes...
April 24, 2024: JAMA
#23
JOURNAL ARTICLE
Humberto Pires, Sérgio Santos-Silva, Andreia V S Cruz, Luís Cardoso, Ana Patrícia Lopes, Maria A Pereira, Carmen Nóbrega, Ana Cristina Mega, Carla Santos, Rita Cruz, Fernando Esteves, Helena Vala, Ana Cristina Matos, Patrícia F Barradas, Ana Cláudia Coelho, João R Mesquita
Coxiella burnetii is the etiologic agent of Q fever, a worldwide zoonosis. Cattle, sheep and goats are considered the main reservoirs of the disease. Transmission to humans occurs mainly through the inhalation of infectious aerosols from milk, faeces, urine, and birth products from infected ruminants. In this study, a 2-year longitudinal approach was performed to ascertain the excretion of C. burnetii in bulk tank milk samples of sheep from a mountain plateau in central Portugal, with sampling conducted during the years 2015 and 2016...
April 24, 2024: Veterinary Research Communications
#24
JOURNAL ARTICLE
Ali S Al-Sarar, Yasser Abobakr, Ali A Alzabib, Amgad A Saleh
We report the first record of the occurrence of the banana weevil, Cosmopolites sordidus (Germar, 1823) (Coleoptera: Curculionidae), an economically important pest of bananas (Musa spp.), from Fifa Mountains in Saudi Arabia. Moreover, we recorded the first observation of damage caused to bananas by C. sordidus in a banana farm in Jazan Province, southwestern Saudi Arabia, in March 2022. Molecular characterization using DNA sequences of the mitochondrial COI gene confirmed the morphological identification of C...
April 24, 2024: Neotropical Entomology
#25
JOURNAL ARTICLE
Davi de Lacerda Ramos, Luís Carlos Leva Borduchi, Raíssa Costa, Eliana Maria Gouveia Fontes, Raul Alberto Laumann, Cristiano Menezes, Theo Mota, Edison Ryoiti Sujii, Carmen Sílvia Soares Pires
The use of Meliponini for crop pollination in protected environments is practically non-existent. One of the reasons is the difficulty of acclimatizing Meliponini to the temperature and light conditions inside greenhouses. We investigated how covering materials used in greenhouses, which filter different intensities of ultraviolet (UV) light, affect the foraging behaviors, flight orientation, attraction to walls and ceilings, and mortality of Scaptotrigona cf. postica (Letreille), Frieseomelitta varia (Lepeletier), and Melipona quadrifasciata (Lepeletier)...
April 24, 2024: Neotropical Entomology
#26
JOURNAL ARTICLE
James W Antoon, Tess Stopczynski, Justin Z Amarin, Laura S Stewart, Julie A Boom, Leila C Sahni, Marian G Michaels, John V Williams, Janet A Englund, Eileen J Klein, Mary A Staat, Elizabeth P Schlaudecker, Rangaraj Selvarangan, Jennifer E Schuster, Geoffrey A Weinberg, Peter G Szilagyi, Ariana Perez, Heidi L Moline, Andrew J Spieker, Carlos G Grijalva, Samantha M Olson, Natasha B Halasa
IMPORTANCE: Studies of influenza in children commonly rely on coded diagnoses, yet the ability of International Classification of Diseases, Ninth Revision codes to identify influenza in the emergency department (ED) and hospital is highly variable. The accuracy of newer International Statistical Classification of Diseases and Related Health Problems, Tenth Revision (ICD-10) codes to identify influenza in children is unknown. OBJECTIVE: To determine the accuracy of ICD-10 influenza discharge diagnosis codes in the pediatric ED and inpatient settings...
April 1, 2024: JAMA Network Open
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JOURNAL ARTICLE
A Dörr, A Flörcken, L Bullinger, D Capper, A Von Deimling, D Kaul, S Märdian, C Starck, D Horst, M P Dragomir, F M Schäfer, A Jarosch
BACKGROUND: Tumor embolism is a very rare primary manifestation of cancers and the diagnosis is challenging, especially if located in the pulmonary arteries, where it can mimic nonmalignant pulmonary embolism. Intimal sarcoma is one of the least commonly reported primary tumors of vessels with only a few cases reported worldwide. A typical location of this malignancy is the pulmonary artery. Herein, we present a case report of an intimal sarcoma with primary manifestation in the pulmonary arteries...
April 24, 2024: Molecular Biology Reports
#28
JOURNAL ARTICLE
Amy S Paller, Stephanie M Rangel, Sarah L Chamlin, Aleena Hajek, Sheshanna Phan, Marcia Hogeling, Leslie Castelo-Soccio, Irene Lara-Corrales, Lisa Arkin, Leslie P Lawley, Tracy Funk, Fabiana Castro Porto Silva Lopes, Richard J Antaya, Michele L Ramien, Karina L Vivar, Joyce Teng, Carrie C Coughlin, Wingfield Rehmus, Deepti Gupta, Lionel Bercovitch, Sarah L Stein, Christina Boull, Wynnis L Tom, Marilyn G Liang, Raegan Hunt, Minnelly Luu, Kristen E Holland, Jennifer J Schoch, David Cella, Jin-Shei Lai, James W Griffith
IMPORTANCE: Chronic skin disorders in children frequently are visible and can cause stigmatization. However, the extent of stigmatization from chronic skin disease and association with mental health needs further study. OBJECTIVE: To examine the extent of stigma, dependence on disease visibility and severity, and association with mental health and quality of life (QOL) in chronic pediatric skin disease. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional, single-visit study was conducted at 32 pediatric dermatology centers in the US and Canada from November 14, 2018, to November 17, 2021...
April 24, 2024: JAMA Dermatology
#29
JOURNAL ARTICLE
Christian J Brakenridge, Annemarie Koster, Bastiaan E de Galan, Alison Carver, Dorothea Dumuid, Francis Q S Dzakpasu, Simone J P M Eussen, Hans H C M Savelberg, Hans Bosma, Neville Owen, Nicolaas C Schaper, Genevieve N Healy, David W Dunstan
AIMS/HYPOTHESIS: The associations of sitting, standing, physical activity and sleep with cardiometabolic health and glycaemic control markers are interrelated. We aimed to identify 24 h time-use compositions associated with optimal metabolic and glycaemic control and determine whether these varied by diabetes status. METHODS: Thigh-worn activPAL data from 2388 participants aged 40-75 years (48.7% female; mean age 60.1 [SD = 8.1] years; n=684 with type 2 diabetes) in The Maastricht Study were examined...
April 24, 2024: Diabetologia
#30
JOURNAL ARTICLE
Sanjay N Gobardhan, Pranobe V Oemrawsingh, Su S Liem, Suzanne C Cannegieter, Martin J Schalij
BACKGROUND: Cardiovascular disease (CVD) imposes a major healthcare burden on young descendants of South Asian migrants living in the western world. In comparison to the native population, the prevalence is significantly higher and the prevalence of CVD risk factors is increasing rapidly. The cardiovascular risk profile and 10-year risk scores of South Asian descendants were evaluated in two cohorts with a 10-year time difference. METHODS: Two cross-sectional studies, conducted in 2004 and 2014, focused on asymptomatic South Asian descendants aged 18-59 years were performed...
April 25, 2024: Coronary Artery Disease
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JOURNAL ARTICLE
McKenzie A Dirr, Areeba Ahmed, Daniel I Schlessinger, Misha Haq, Victoria Shi, Eric Koza, Melissa Ma, Rachel E Christensen, Sarah A Ibrahim, Jochen Schmitt, Lena Johannsen, Yuka Asai, Hilary E Baldwin, Enzo Berardesca, Brian Berman, Ana Carolina Vieira, Anna L Chien, David E Cohen, James Q Del Rosso, Jacquelyn Dosal, Lynn A Drake, Steven R Feldman, Alan B Fleischer, Adam Friedman, Emmy Graber, Julie C Harper, Yolanda R Helfrich, Gregor B Jemec, Sandra M Johnson, Rajani Katta, Peter Lio, Lisa E Maier, George Martin, Arielle R Nagler, Isaac M Neuhaus, Melis Palamar, Lawrence C Parish, Theodore Rosen, Stephen P Shumack, James A Solomon, Emil A Tanghetti, Guy F Webster, Allison Weinkle, Jonathan S Weiss, Edward J Wladis, Ian A Maher, Joseph F Sobanko, Todd V Cartee, Brian A Cahn, Murad Alam, Bianca Y Kang, Sanjana Iyengar, Noor Anvery, Erkan Alpsoy, Anthony Bewley, Clio Dessinioti, Alexander Egeberg, Burhan Engin, Harald P M Gollnick, Dimitrios Ioannides, Hei Sung Kim, Elizabeth Lazaridou, Ji Li, Hester Gail Lim, Giuseppe Micali, Clivia Maria Moraes de Oliveira, Lucero Noguera-Morel, Aurora Parodi, Markus Reinholz, Dae Hun Suh, Qiuning Sun, Esther J van Zuuren, Uwe Wollina, Youwen Zhou, Catherine Zip, Emily Poon, Ross Pearlman
IMPORTANCE: Inconsistent reporting of outcomes in clinical trials of rosacea is impeding and likely preventing accurate data pooling and meta-analyses. There is a need for standardization of outcomes assessed during intervention trials of rosacea. OBJECTIVE: To develop a rosacea core outcome set (COS) based on key domains that are globally relevant and applicable to all demographic groups to be used as a minimum list of outcomes for reporting by rosacea clinical trials, and when appropriate, in clinical practice...
April 24, 2024: JAMA Dermatology
#32
JOURNAL ARTICLE
John A Lutkenhaus, Junaid U Ahmed, Mehedi Hasan, Derek C Prosser, Julio C Alvarez
We recorded current-time ( i - t ) profiles for oxidizing ferrocyanide (FCN) while spherical yeast cells of radius ( r c ≈ 2 μm) collided with disk ultramicroelectrodes (UMEs) of increasing radius ( r e ≈ 12-45 μm). Collision signals appear as minority steps and majority blips of decreased current overlayed on the i - t baseline when cells block ferrocyanide flux ( J FCN ). We assigned steps to adsorption events and blips to bouncing collisions or contactless passages. Yeast cells exhibit impact signals of long duration (Δ t ≈ 15-40 s) likely due to sedimentation...
April 24, 2024: Analyst
#33
REVIEW
Bubul Das, Anjali Dahiya, Bhisma K Patel
Owing to their unique structural features, isothiocyanates (ITCs) are a class of highly useful and inimitable reagents as the -NCS group serves both as electrophile and nucleophile in organic synthesis. ITCs share a rich legacy in organic, medicinal, and combinatorial chemistry. Compared to their oxygen equivalents, isocyanates, ITCs are easily available, less unpleasant, and somewhat less harmful to work with (mild conditions) which makes them happy-go-lucky reagents. Functionalized ITCs can finely tune the reactivity of the -NCS group and thus can be exploited in the late-stage functionalization processes...
April 24, 2024: Organic & Biomolecular Chemistry
#34
JOURNAL ARTICLE
Regina S Wright, Alexa C Allan, Alyssa A Gamaldo, Adrienne A Morgan, Anna K Lee, Guray Erus, Christos Davatzikos, Desirée C Bygrave
It is not well understood how neighborhood disadvantage is associated with specific domains of cognitive function and underlying brain health within older adults. Thus, the objective was to examine associations between neighborhood disadvantage, brain health, and cognitive performance, and examine whether associations were more pronounced among women. The study included 136 older adults who underwent cognitive testing and MRI. Neighborhood disadvantage was characterized using the Area Deprivation Index (ADI)...
April 24, 2024: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
#35
JOURNAL ARTICLE
Thuy T M Ngo, Bailey Liu, Feng Wang, Aakash Basu, Carl Wu, Taekjip Ha
The organization of nucleosomes into chromatin and their accessibility are shaped by local DNA mechanics. Conversely, nucleosome positions shape genetic variations, which may originate from mismatches during replication and chemical modification of DNA. To investigate how DNA mismatches affect the mechanical stability and the exposure of nucleosomal DNA, we used an optical trap combined with single-molecule FRET and a single-molecule FRET cyclization assay. We found that a single base-pair C-C mismatch enhances DNA bendability and nucleosome mechanical stability for the 601-nucleosome positioning sequence...
April 24, 2024: ELife
#36
JOURNAL ARTICLE
Ayman M Elghonemy, Fadia S Attia, Michael C Brodsky
PURPOSE: To elucidate the induced effects of horizontal strabismus on the Bielschowsky Head Tilt Test (BHTT). DESIGN: Prospective clinical study. METHODS: Prospective analysis of BHTT testing in 85 patients with exotropia and 71 patients with esotropia who were examined in a strabismus clinic. RESULTS: Eighty-four of 85 patients with exotropia (98.82%) showed a positive BHTT with an induced hyperdeviation on the side of the tilt (to both sides in 67% and to one side in 32%)...
April 24, 2024: Journal of Binocular Vision and Ocular Motility
#37
JOURNAL ARTICLE
Jaydeep Banerjee, Subhasis Batabyal, Suman Biswas, Debaraj Bhattacharyya, Md Habib, Arun K Das, Pramod K Nanda, Indranil Samanta, Premanshu Dandapat, Samiran Bandyopadhyay
This study depicts the drug-resistance and phylogenomic characteristics of 365 Escherichia coli (EC) and 76 Klebsiella pneumoniae (KP) isolated from stray dogs (293) in and around Kolkata, India. Initial screening found 59 isolates, including 48 E. coli and 11 KP multidrug resistant, which included 33 extended-spectrum β-lactamase, 41 AmpC β-lactamase and 18 metallo-β-lactamase producers carrying bla NDM-1 (11) and bla NDM-5 (7) genes. Majority of them had the resistant genes such as bla CTX-M (33), bla TEM (18), bla SHV (4), bla OXA (17), bla FOX (2), bla DHA (2), bla CITM (15), bla CMY-2 (13), bla GES (2) and bla VEB (2), qnr S (15), qnr B (3), aac-6'-Ib-cr (14), tet A (26), tet B (14), sul -1 (25), arm A (2) and rmt B (6), in addition to adherence genes such as csg A (33), fim A (27), fli C (13), sdi A (33), rcs A (38), and rpo S (39)...
April 23, 2024: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
#38
JOURNAL ARTICLE
D D Cruz Nieto, N E Muguruza Crispin, C M Caira Mamani, H J Castro Bartolomé, M A Inga Sotelo, M N M Alberto, A S Valderrama Romero, V C Vargas Godoy, J M More López, H E Chanducas Tantaleán, N E Menacho Javier, M A Lara Castillo, W Flores Casanova, E R Benavente Ramírez, L A Apolín Montes, F Diestra Salinas
The increase in prices of fertilizers, energy and other materials necessary for the industry triggered a global economic crisis. Reason that was investigated on the biological and chemical characteristics in relation to the yield of radish nourished with humus from plant residue. The objective was to determine the appropriate dose of humus to obtain greater yield and its relationship with the chemical and biological characteristics of the radish. It is based on applied methodology with an experimental approach; Therefore, the Completely Random Block Design model was used, which consisted of 3 blocks and 5 treatments that were T1 with 0, T2 with 4, T3 with 6, T4 with 8 and T5 with 10 t/ha of humus and They applied 15 days after sowing...
2024: Brazilian Journal of Biology
#39
JOURNAL ARTICLE
F J W S Siqueira, F A P Rodrigues, S A Ribeiro, H N Veras, F C S Ferreira, R C L Siqueira, A A Dos Santos, A Havt, A A M Lima
Diabetic-metabolic syndrome (MetS-D) has a high prevalence worldwide, in which an association with the rupture of the intestinal epithelium barrier function (IEBF) has been pointed out, but the functional and morphological properties are still not well understood. This study aimed to evaluate the impact of acute hyperglycemia diabetes on intestinal tight junction proteins, metabolic failure, intestinal ion and water transports, and IEBF parameters. Diabetes was induced in male Rattus norvegicus (200-310 g) with 0...
2024: Brazilian Journal of Medical and Biological Research
#40
RANDOMIZED CONTROLLED TRIAL
H C Almeida, V K S Lage, R Taiar, J M Santos, F A de Paula, A Rapin, D C Sá-Caputo, M Bernardo-Filho, A C R Lacerda, V A Mendonça
Sarcopenia is a pathology resulting from a progressive and severe loss of muscle mass, strength, and function in the course of aging, which has deleterious consequences on quality of life. Among the most widespread studies on the issue are those focused on the effect of different types of physical exercise on patients with sarcopenia. This randomized controlled study aimed to compare the effects of a whole-body vibration exercise (WBV) session on the inflammatory parameters of non-sarcopenic (NSG, n=22) and sarcopenic elderly (SG, n=22)...
2024: Brazilian Journal of Medical and Biological Research
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