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https://www.readbyqxmd.com/read/28728559/effect-of-insulin-therapy-and-dietary-adjustments-on-safety-and-performance-during-simulated-soccer-tests-in-people-with-type-1-diabetes-study-protocol-for-a-randomized-controlled-trial
#1
Javier Calvo-Marín, Gabriel Torrealba-Acosta, Matthew Campbell, Jesse Gaboury, Ajmol Ali, Chih Hao Chen-Ku
BACKGROUND: Despite the reduction in glycemic derangement in patients with type 1 diabetes mellitus (T1D) through dietary and therapeutic adjustments implemented before, during and after continuous exercise, evidence for its effectiveness with intermittent forms of exercise, such as soccer, is still lacking. METHODS/DESIGN: We designed a study protocol for a randomized, crossover, double-blinded, controlled trial, for the evaluation of the effect that a strategy of dietary and therapeutic modifications may have on safety and performance of persons with T1D in soccer training sessions and cognitive testing...
July 20, 2017: Trials
https://www.readbyqxmd.com/read/28719865/antioxidant-effect-of-exercise-exploring-the-role-of-the-mitochondrial-complex-i-superassembly
#2
J R Huertas, S Al Fazazi, A Hidalgo-Gutierrez, L C López, R A Casuso
Mitochondrial respiratory complexes become assembled into supercomplexes (SC) under physiological conditions. One of the functional roles of these entities is the limitation of reactive oxygen species (ROS) produced by complex I (CI) of the respiratory chain. We sought to determine whether the systemic antioxidant effect of exercise is mediated by the assembly of mitochondrial CIs into SCs in rats. Male Wistar rats were exercise trained or remained sedentary for ten weeks; then, blood samples were collected, and the gastrocnemius muscle was isolated...
July 11, 2017: Redox Biology
https://www.readbyqxmd.com/read/28715424/atrophy-of-gluteus-maximus-among-women-with-a-history-of-chronic-low-back-pain
#3
Amy H Amabile, John H Bolte, Saskia D Richter
BACKGROUND: Although the relationship between low back pain (LBP) and the size of certain trunk muscles has been extensively studied, the relationship between gluteus maximus (GM) size and LBP has been only minimally examined. Determining whether such a relationship exists would help improve our understanding of the etiology of LBP, and possibly provide a rationale for the use of therapeutic exercise interventions targeting GM with LBP patients. The objective of this study was to compare gluteus maximus cross-sectional area in individuals with chronic LBP, and in a group of individuals without LBP...
2017: PloS One
https://www.readbyqxmd.com/read/28714749/the-influence-of-verbal-and-tactile-feedback-on-electromyographic-amplitude-of-the-shoulder-musculature-during-common-therapeutic-exercises
#4
Sean A Jones, Derek N Pamukoff, Timothy C Mauntel, J Troy Blackburn, Joseph B Myers
CONTEXT: Verbal and tactile feedback during rehabilitation exercises can improve muscle activation, thus improving the therapeutic benefits. However, it is unclear which feedback method elicits the greatest electromyographic (EMG) amplitude. OBJECTIVE: To determine if the addition of tactile to verbal feedback increases EMG amplitude of selected shoulder musculature during scapular plane elevation (Y's), shoulder horizontal abduction with external rotation (T's), and scapular retraction with external rotation (W's)...
July 17, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28713116/therapeutic-evaluation-of-cervical-dysfunction-in-patients-with-myofascial-pain-dysfunction-syndrome-a-prospective-study
#5
B Smriti Jagdhari, Motwani Mukta, A Golhar Saket, Anil V Golhar
AIM: The aim of this study was to find out the therapeutic correlation between cervical dysfunction and myofascial pain dysfunction syndrome (MPDS). MATERIALS AND METHODS: The study included 46 patients out of which 23 had MPDS with cervical pain (group I), and 23 patients had only MPDS (group II). Detailed history and examination of the patients were carried out, and the factors taken into consideration were pain and tenderness of muscles of mastication and neck muscles, maximum comfortable mouth opening, and cervical range of motion...
July 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28712264/treadmill-exercise-ameliorates-the-regulation-of-energy-metabolism-in-skeletal-muscle-of-nse-ps2mtransgenic-mice-with-alzheimer-s-disease
#6
Jang-Soo Yook, Joon-Yong Cho
PURPOSE: Alzheimer's disease (AD) is classified as a progressive neurological disorder, which not only causes cognitive impairment but also abnormal weight loss, with a reduction of muscle mass related to the accumulation of amyloid-β (Aβ) in skeletal muscle. Thus, we investigated the effect of treadmill exercise on Aβ deposition, and p-AMPK, p-ACC, BDNF, and GLUT4 protein levels the regulation of muscle energy metabolism using an AD mouse. METHODS: At 13 months of age, NSE/PS2m mice (Tg) and control mice (non-Tg) were assigned to non-exercise control (Con) and exercise groups (Exe)...
March 31, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28709659/in-vivo-hip-joint-loads-and-pedal-forces-during-ergometer-cycling
#7
P Damm, J Dymke, A Bender, G Duda, G Bergmann
The rising prevalence of osteoarthritis and an increase in total hip replacements calls for attention to potential therapeutic activities. Cycling is considered as a low impact exercise for the hip joint and hence recommended. However, there are limited data about hip joint loading to support this claim. The aim of this study was to measure synchronously the in vivo hip joint loads and pedal forces during cycling. The in vivo hip joint loads were measured in 5 patients with instrumented hip implants. Data were collected at several combinations of power and cadence, at two saddle heights...
July 5, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28708742/physical-therapy-and-exercise-interventions-in-huntington-s-disease-a-mixed-methods-systematic-review-protocol
#8
Lori Quinn, Monica Busse, Judith Carrier, Nora Fritz, Jane Harden, Lynda Hartel, Deb Kegelmeyer, Anne Kloos, Ashwini Rao
The review seeks to evaluate the effectiveness of physical therapy and exercise interventions in Huntington's disease (HD). The review question is: What is the effectiveness of physiotherapy and therapeutic exercise interventions in people with HD, and what are patients', families' and caregivers' perceptions of these interventions?The specific objectives are:This mixed methods review seeks to develop an aggregated synthesis of quantitative, qualitative and narrative systematic reviews on physiotherapy and exercise interventions in HD, in an attempt to derive conclusions and recommendations useful for clinical practice and policy decision-making...
July 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28708468/a-botanical-composition-from-morus-alba-ilex-paraguariensis-and-rosmarinus-officinalis-for-body-weight-management
#9
Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Hyun-Jin Kim, Jeong-Bum Nam, Mi-Ran Kim, Qi Jia
Obesity is the largest and fastest growing public health catastrophe in the world affecting both adults and children with a prevalence impacting more than one-third of United States (US) adult population. Although the long-term solution lies in lifestyle changes in the form of dieting and exercise, intervention is required for those who are already obese. Unfortunately, treatment options remain quite limited due to associated side effects of conventional therapeutics. As a natural alternative, in this study we describe the beneficial effect of a standardized composition (UP603) comprised of extracts from Morus alba, Ilex paraguariensis, and Rosmarinus officinalis in improving metabolic disorders in high fat diet (HFD) and high fat & high fructose diet (HFFD) induced obese C57BL/6J mice...
July 14, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28706513/bacteriocin-antimicrobial-synergy-a-medical-and-food-perspective
#10
REVIEW
Harsh Mathur, Des Field, Mary C Rea, Paul D Cotter, Colin Hill, R Paul Ross
The continuing emergence of multi-drug resistant pathogens has sparked an interest in seeking alternative therapeutic options. Antimicrobial combinatorial therapy is one such avenue. A number of studies have been conducted, involving combinations of bacteriocins with other antimicrobials, to circumvent the development of antimicrobial resistance and/or increase antimicrobial potency. Such bacteriocin-antimicrobial combinations could have tremendous value, in terms of reducing the likelihood of resistance development due to the involvement of two distinct mechanisms of antimicrobial action...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28705298/methamphetamine-related-disorders
#11
Euphrosyne Gouzoulis-Mayfrank, Roland Härtel-Petri, Willem Hamdorf, Ursula Havemann-Reinecke, Stephan Mühlig, Norbert Wodarz
BACKGROUND: Methamphetamine is considered more dangerous than other stimulants because of its acute complications, long-term neurotoxicity, and potential for drug dependence. Until now, there have been no evidence-based guidelines for the treatment of methamphetamine-related disorders, either in Germany or abroad. METHODS: A systematic literature search was performed on the treatment of methamphetamine-related disorders. Based on this literature review, a multidisciplinary expert panel developed recommendations using the nominal group technique...
June 30, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28704936/effects-of-a-new-nutraceutical-formulation-berberine-red-yeast-rice-and-chitosan-on-non-hdl-cholesterol-levels-in-individuals-with-dyslipidemia-results-from-a-randomized-double-blind-placebo-controlled-study
#12
Valentina Spigoni, Raffaella Aldigeri, Monica Antonini, Maria Maddalena Micheli, Federica Fantuzzi, Andrea Fratter, Marzia Pellizzato, Eleonora Derlindati, Ivana Zavaroni, Riccardo C Bonadonna, Alessandra Dei Cas
Increased non high-density lipoprotein (HDL)/low-density lipoprotein (LDL) cholesterol levels are independent risk factors for cardiovascular (CV) mortality with no documented threshold. A new combination of nutraceuticals (berberine 200 mg, monacolin K 3 mg, chitosan 10 mg and coenzyme Q 10 mg) with additive lipid-lowering properties has become available. The aim of the study is to test the efficacy of the nutraceutical formulation (one daily) in lowering non-HDL cholesterol vs. placebo at 12 weeks in individuals with non-HDL-cholesterol levels ≥160 mg/dL...
July 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28704193/rehabilitation-of-patients-with-hip-joint-arthroplasty-late-post-surgery-period-hospital-rehabilitation
#13
Maya S Krastanova, Elena M Ilieva, Danelina E Vacheva
BACKGROUND: Hip joint replacement (endoprosthesis, alloplasty) has become one of the most frequent surgery interventions of the 20th century. AIM: To conduct rehabilitation therapy in the late post-surgery period of hospital rehabilitation (45 days after surgery), to track patients' progress and measure the results. MATERIALS AND METHODS: One hundred and fifty-two patients with hip joint endoprosthesis were included in the study. All underwent surgery and rehabilitation at the Department of Clinical Rehabilitation of the Physical and Rehabilitation Medicine Clinic at Doctor G...
June 1, 2017: Folia Medica
https://www.readbyqxmd.com/read/28703038/rehabilitation-interventions-to-modify-endocrine-metabolic-disease-risk-in-individuals-with-chronic-spinal-cord-injury-living-in-the-community-riisc-a-systematic-review-and-scoping-perspective
#14
Jenna C Gibbs, Dany H Gagnon, Austin J Bergquist, Jasmine Arel, Tomas Cervinka, Rasha El-Kotob, Désirée B Maltais, Dalton L Wolfe, B Catharine Craven
Context Endocrine-metabolic disease (EMD) risk following spinal cord injury (SCI) is associated with significant multi-morbidity (i.e. fracture, diabetes, heart disease), mortality, and economic burden. It is unclear to what extent rehabilitation interventions can modify EMD risk and improve health status in community-dwelling adults with chronic SCI. Objectives To characterize rehabilitation interventions and summarize evidence on their efficacy/effectiveness to modify precursors to EMD risk in community-dwelling adults with chronic SCI...
July 13, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28697785/effect-of-aquatic-physical-therapy-on-pain-perception-functional-capacity-and-quality-of-life-in-older-people-with-knee-osteoarthritis-study-protocol-for-a-randomized-controlled-trial
#15
Guilherme Eleutério Alcalde, Ana Carolina Fonseca, Thais Fernanda Bôscoa, Mirella Regina Gonçalves, Gabriele Candido Bernardo, Bruna Pianna, Bianca Ferdin Carnavale, Camila Gimenes, Silvia Regina Barrile, Eduardo Aguilar Arca
BACKGROUND: Aquatic therapy promotes short-term benefits for patients with knee osteoarthritis (OA), and it may be the first therapeutic option for this pathological condition. The objective of this study was to investigate the effects of an aquatic therapy program on pain intensity, functional ability, and quality of life in older people with knee OA. METHODS/DESIGN: This is a parallel, two-arm, open, randomized controlled clinical trial with older people with knee OA...
July 11, 2017: Trials
https://www.readbyqxmd.com/read/28697015/the-p50-research-center-in-perioperative-sciences-how-the-investment-by-the-national-institute-of-general-medical-sciences-in-team-science-has-reduced-post-burn-mortality
#16
Celeste C Finnerty, Karel Capek, Charles Voigt, Gabriel Hundeshagen, Janos Cambiaso-Daniel, Craig Porter, Linda E Sousse, Amina El Ayadi, Ramon Zapata-Sirvent, Ashley Guillory, Oscar E Suman, David N Herndon
Since the inception of the P50 Research Center in Peri-Operative Sciences (RCIPS) funding mechanism, the National Institute for General Medical Sciences has supported a team approach to science. Many advances in critical care, particularly burns, have been driven by RCIPS teams. In fact, burns that were fatal in the early 1970s, prior to the inception of the P50 RCIPS program, are now routinely survived as a result of the P50-funded research. The advances in clinical care that led to the reduction in post-burn death were made by optimizing resuscitation, incorporating early excision and grafting, bolstering acute care including support for inhalation injury, modulating the hypermetabolic response, augmenting the immune response, incorporating aerobic exercise, and developing anti-scarring strategies...
July 8, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28694221/nordic-walking-for-the-management-of-people-with-parkinson-s-disease-a-systematic-review
#17
REVIEW
Lucia Cugusi, Andrea Manca, Daniele Dragone, Franca Deriu, Paolo Solla, Claudio Secci, Marco Monticone, Giuseppe Mercuro
BACKGROUND: It is well known that physical exercise is the main therapeutic element of rehabilitation programs for people with Parkinson's disease (PD). As traditional forms of exercise can guarantee significant health benefits, the emergence of non-conventional physical activities, such as Nordic walking (NW), may add positive effects. OBJECTIVE: To appraise the available evidence on the main effects of NW in the rehabilitation programs for people with PD and to propose a design for upcoming research that might improve the uniformity of future trials...
July 7, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28690704/experienced-practitioners-beliefs-utilized-to-create-a-successful-massage-therapist-conceptual-model-a-qualitative-investigation
#18
Anne B Kennedy, Niki Munk
BACKGROUND: The massage therapy profession in the United States has grown exponentially, with 35% of the profession's practitioners in practice for three years or less. Investigating personal and social factors with regard to the massage therapy profession could help to identify constructs needed to be successful in the field. PURPOSE: This data-gathering exercise explores massage therapists' perceptions on what makes a successful massage therapist that will provide guidance for future research...
June 2017: International Journal of Therapeutic Massage & Bodywork
https://www.readbyqxmd.com/read/28689206/guide-for-current-nutrigenetic-nutrigenomic-and-nutriepigenetic-approaches-for-precision-nutrition-involving-the-prevention-and-management-of-chronic-diseases-associated-with-obesity
#19
Omar Ramos-Lopez, Fermín I Milagro, Hooman Allayee, Agata Chmurzynska, Myung Sook Choi, Rui Curi, Raffaele De Caterina, Lynnette R Ferguson, Leticia Goni, Jing X Kang, Martin Kohlmeier, Amelia Marti, Luis A Moreno, Louis Pérusse, Chandan Prasad, Lu Qi, Ram Reifen, Jose I Riezu-Boj, Rodrigo San-Cristobal, Jose Luis Santos, J Alfredo Martínez
Chronic diseases, including obesity, are major causes of morbidity and mortality in most countries. The adverse impacts of obesity and associated comorbidities on health remain a major concern due to the lack of effective interventions for prevention and management. Precision nutrition is an emerging therapeutic approach that takes into account an individual's genetic and epigenetic information, as well as age, gender, or particular physiopathological status. Advances in genomic sciences are contributing to a better understanding of the role of genetic variants and epigenetic signatures as well as gene expression patterns in the development of diverse chronic conditions, and how they may modify therapeutic responses...
July 8, 2017: Journal of Nutrigenetics and Nutrigenomics
https://www.readbyqxmd.com/read/28686557/the-biopsychosocial-model-40-years-of-application-in-psychiatry
#20
G Papadimitriou
In 1977, the American pathologist and psychiatrist George Engel (1913-1999) published in the Journal Science his paper "TheIn 1977, the American pathologist and psychiatrist George Engel (1913-1999) published in the Journal Science his paper "Theneed for a new medical model: A challenge for biomedicine", introducing the term Biopsychosocial Model. This model basedon the results of Engel's studies in ulcerative colitis, depression and psychogenic pain, constituted a challenge for biomedicineand the biomedical model...
April 2017: Psychiatrikē, Psychiatriki
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