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Denervation radiofrequency

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https://www.readbyqxmd.com/read/27916745/transcatheter-non-contact-microwave-ablation-may-enable-circumferential-renal-artery-denervation-while-sparing-the-vessel-intima-and-media
#1
Pierre C Qian, Michael A Barry, Sara Al-Raisi, Pramesh Kovoor, Jim Pouliopoulos, Chrishan Nalliah, Abhishek Bhaskaran, William Chik, Rahul Kurup, Virginia James, Winny Varikatt, Alistair McEwan, Aravinda Thiagalingam, Stuart P Thomas
AIMS: Trials of transcatheter renal artery denervation (RDN) have failed to show consistent antihypertensive efficacy. Procedural factors and limitations of radiofrequency ablation can lead to incomplete denervation. We hypothesized that non-contact microwave catheter ablation could produce deep circumferential perivascular heating while avoiding the renal artery intima and media injury. METHOD AND RESULTS: A novel microwave catheter was designed and tested in a renal artery model consisting layers of phantom materials embedded with a thermochromic liquid crystal sheet, colour range 50-78°C...
December 6, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27890862/randomized-blinded-and-controlled-comparative-study-of-chemical-and-radiofrequency-based-renal-denervation-in-a-porcine-model
#2
Stefan Bertog, Tim A Fischell, Félix Vega, Vartan Ghazarossian, Atul Pathak, Laura Vaskelyte, Darrin Kent, Horst Sievert, Elena Ladich, Kazuyuki Yahagi, Renu Virmani
AIMS: The blood pressure lowering effect of percutaneous renal denervation (RDN) is controversial. Success of RDN may be device-dependent. We sought to compare the efficacy of RDN by chemical neurolysis using alcohol (Peregrine System™ Infusion Catheter, Ablative Solutions, Inc. Menlo Park, CA, USA) to RDN by radiofrequency (RF) ablation with the single-electrode RF catheter (Symplicity™ Flex, Medtronic Inc., Minneapolis, MN, USA) in a porcine model. METHODS AND RESULTS: This was a prospective, randomized, blinded study...
November 29, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27735104/a-modified-posterolateral-approach-for-radiofrequency-denervation-of-the-medial-branch-of-the-cervical-segmental-nerve-in-cervical-facet-joint-pain-based-on-anatomical-considerations
#3
Maarten van Eerd, Arno Lataster, Micha Sommer, Jacob Patijn, Maarten van Kleef
The cervical facet joints, also called the zygapophyseal joints, are a potential source of neck pain (cervical facet joint pain). The cervical facet joints are innervated by the cervical medial branches (CMBs) of the cervical segmental nerves. Cervical facet joint pain has been shown to respond to multisegmental radiofrequency denervation of the cervical medial branches. This procedure is performed under fluoroscopic guidance. Currently, three approaches are described and used. Those three techniques of radiofrequency treatment of the CMBs, classified on the base of the needle trajectory toward the anatomical planes, are as follows: the posterolateral technique, the posterior technique, and the lateral technique...
October 13, 2016: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/27673128/poster-374-sexual-dysfunction-after-sacroiliac-joint-radiofrequency-denervation-a-case-report
#4
Ada Lyn Yao, Charles A Odonkor, David Taftian, Akhil Chhatre
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27636921/-criteria-for-selecting-patients-with-resistant-hypertension-for-a-renal-sympathetic-denervation
#5
T M Ripp, T Yu Rebrova, V F Mordovin, S A Afanas'ev, S E Pekarsky, G V Semke, A Yu Fal'kovskaya, V A Lichikaki, E V Tsymbalyuk
AIM: to define and develop a procedure that can select patients with resistant hypertension (RH) for a renal sympathetic denervation (RSD) procedure, by being orienting to the specific initial values of β-adrenoreactivity (β-AR) and systolic blood pressure (SBP). SUBJECTS AND METHODS: The analysis included 23 RH patients receiving the maximally tolerable doses of 4 antihypertensive drugs. The investigations involving BP control and a Russian spectrophotometric procedure for determining β-AR in terms of the change in the osmoresistance of erythrocyte membranes (EM) were performed at baseline and 4 and 24 weeks...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27636920/-possibility-of-evaluating-the-effectiveness-of-renal-artery-sympathetic-denervation-in-resistant-hypertension-early-after-radiofrequency-ablation
#6
T Yu Rebrova, T M Ripp, S A Afanas'ev, V F Mordovin, E F Muslimova
AIM: to investigate time course of changes in the adrenoreactivity (AR) of erythrocyte membranes (EM) after radiofrequency ablation of the synaptic nerves of the renal arteries (RA) in patients with resistant hypertension (RH) and to assess whether this indicator can be used for the early evaluation of the efficiency of an invasive intervention into the RA. SUBJECTS AND METHODS: 24 patients with RH, who received full-dose antihypertensive therapy with at least three drugs, including a diuretic, were examined...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27618781/percutaneous-radiofrequency-facet-capsule-denervation-as-an-alternative-target-in-lumbar-facet-syndrome
#7
Wael Mohamed Mohamed Moussa, Wael Khedr
OBJECTIVES: Percutaneous radiofrequency denervation of the medial dorsal branch is often used in chronic low back pain of intervertebral facet etiology, which is sometimes difficult to perform and recurrence of pain often ensues. We theorized that shifting the target of RF coagulation to the facet joint capsule would provide an easier target and a longer-lived pain relieving response. PATIENTS AND METHODS: A prospective randomized controlled trial where 120 patients diagnosed with CLBP of a confirmed facet origin were randomly divided into three equal groups, the first was submitted to percutaneous radiofrequency coagulation of the facet joint capsule, the second underwent percuataneous denervation of the medial dorsal branch and the third did not receive radiofrequency lesioning...
November 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27617388/anatomical-and-procedural-determinants-of-catheter-based-renal-denervation
#8
Sebastian Ewen, Christian Ukena, Thomas Felix Lüscher, Martin Bergmann, Peter J Blankestijn, Erwin Blessing, Bodo Cremers, Oliver Dörr, Dagmara Hering, Lukas Kaiser, Holger Nef, Elias Noory, Markus Schlaich, Faisal Sharif, Isabella Sudano, Britta Vogel, Michiel Voskuil, Thomas Zeller, Abraham R Tzafriri, Elazer R Edelman, Lucas Lauder, Bruno Scheller, Michael Böhm, Felix Mahfoud
BACKGROUND/PURPOSE: Catheter-based renal sympathetic denervation (RDN) can reduce blood pressure (BP) and sympathetic activity in certain patients with uncontrolled hypertension. Less is known about the impact of renal anatomy and procedural parameters on subsequent BP response. METHODS/MATERIALS: A total of 564 patients with resistant hypertension underwent bilateral RDN in 9 centers in Europe and Australia using a mono-electrode radiofrequency catheter (Symplicity Flex, Medtronic)...
October 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/27551419/-simplicity-radiofrequency-neurotomy-of-sacroiliac-joint-a-real-life-1-year-follow-up-uk-data
#9
Vinay S Anjana Reddy, Chhaya Sharma, Kuang-Yi Chang, Vivek Mehta
BACKGROUND: Sacroiliac joint (SIJ) pain is considered to be the third most common cause of low back pain with the prevalence of 13-25% in all low back pain patients. Its diagnosis and treatment remain a challenge with the poor evidence base for interventional procedures. Patients with SIJ pain experience a low quality of life, worse than some of the chronic health conditions. Simplicity radiofrequency (RF) neurotomy is a novel technique which tackles some of the problems faced by conventional RF neurotomy and may offer better results in managing pain arising from SIJ...
May 2016: British Journal of Pain
https://www.readbyqxmd.com/read/27538721/sympathoinhibitory-effect-of-radiofrequency-renal-denervation-in-spontaneously-hypertensive-rats-with-established-hypertension
#10
Juan Gao, Edmund K Kerut, Frank Smart, Akemi Katsurada, Dale Seth, L Gabriel Navar, Daniel R Kapusta
BACKGROUND: Radiofrequency ablation of the renal arteries (RF-ABL) has been shown to decrease blood pressure (BP) in drug-resistant hypertensive patients who receive antihypertensive drug therapy. However, there remain questions regarding how RF-ABL influences BP independent of drug therapy and whether complete renal denervation is necessary to maximally lower BP. To study these questions, we examined the cardiovascular, sympathetic, and renal effects produced by RF-ABL of the proximal renal arteries in spontaneously hypertensive rats (SHR) with established hypertension...
August 18, 2016: American Journal of Hypertension
https://www.readbyqxmd.com/read/27529585/resistant-hypertension-comparison-of-unifocal-versus-multifocal-radiofrequency-ablation-for-renal-denervation-up-to-24months-follow-up
#11
Dirk Prochnau, Christina Schweizer, Matthias Hoyme, Hans-Reiner Figulla, P Christian Schulze, Ralf Surber
No abstract text is available yet for this article.
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27528372/renal-denervation-in-patients-with-loin-pain-hematuria%C3%A2-syndrome
#12
Bhanu Prasad, Shelley Giebel, Francisco Garcia, Kunal Goyal, Jennifer Rose St Onge
Loin pain hematuria syndrome (LPHS) is a painful and incapacitating condition that typically affects young women. Treatment options, including opiates and/or surgical denervation of the renal nerves by autotransplantation, have variable success. In this report, we describe the successful use of endovascular renal nerve ablation in this population. Four women with LPHS and intractable pain unresponsive to conservative measures underwent endovascular ablation of the renal nerves between July and November 2015 using the Vessix renal denervation system...
August 12, 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/27493150/accessory-renal-arteries-prevalence-in-resistant-hypertension-and-an-important-role-in-nonresponse-to-radiofrequency-renal-denervation
#13
Paige VonAchen, Jason Hamann, Thomas Houghland, John R Lesser, Yale Wang, David Caye, Kristi Rosenthal, Ross F Garberich, Mary Daniels, Robert S Schwartz
OBJECTIVE: The aim of this study was to understand the role of accessory renal arteries in resistant hypertension, and to establish their role in nonresponse to radiofrequency renal denervation (RDN) procedures. BACKGROUND: Prior studies suggest a role for accessory renal arteries in hypertensive syndromes, and recent clinical trials of renal denervation report that these anomalies are highly prevalent in resistant hypertension. This study evaluated the relationships among resistant hypertension, accessory renal arteries, and the response to radiofrequency (RF) renal denervation...
October 2016: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/27442000/an-investigation-on-the-effect-of-improved-x-rays-guided-radiofrequency-thermocoagulation-denervation-on-lumbar-facet-joint-syndrome
#14
Qin Zhou, Fang Zhou, Long Wang, Kang Liu
OBJECTIVES: This study aims to observe the clinical efficacy and feasibility of improved X-rays-guided radiofrequency thermocoagulation denervation for treating low back pain secondary to lumbar facet joint syndrome (LFJS). PATIENTS AND METHODS: Eighty LFJS patients were randomly assigned into two groups: the denervation group (n=40), treated with percutaneous radiofrequency thermocoagulation denervation on the lumbar facet joint, and the control group (n=40), injected with betamethasone and lidocaine into the lumbar facet joint...
September 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27429632/one-year-follow-up-effect-of-renal-sympathetic-denervation-in-patients-with-resistant-hypertension
#15
Masoud Pourmoghaddas, Alireza Khosravi, Mohammadreza Akhbari, Mojtaba Akbari, Mohamadreza Pourbehi, Fereshteh Ziaei, Leila Salehizade, Nahid Sistan, Masoumeh Esmaeili, Peyman Bidram
BACKGROUND: Resistant hypertension is a common clinical problem of blood pressure that is not controlled despite the simultaneous application of multiple antihypertensive agents. Ablation of renal afferent nerves has been applied and proved to decrease hypertension and injuries produced by severe sympathetic hyperactivity. The main objective of this study was to investigate the long-term effect of renal artery sympathetic ablation and its complications in patients with treatment-resistant hypertension...
March 2016: ARYA Atherosclerosis
https://www.readbyqxmd.com/read/27383322/effects-of-local-radiofrequency-denervation-on-ventricular-electrophysiological-properties-in-normal-and-acute-myocardial-ischemia-heart
#16
Y Huang, D-N Wang, P Liu, Y Song, H-M Cui, J-Y Zhang, J Blackwell, D-N Liao
OBJECTIVE: To observe the effects of local radiofrequency denervation on ventricular effective refractory periods, electrical alternans and ventricular arrhythmia susceptibility post myocardial infarction. MATERIALS AND METHODS: Thirty-four mongrel dogs were randomly divided into the normal heart group (n = 16, 8 in sham and 8 in local sympathetic denervation - LSD) and the acute myocardial ischemia (AMI) group (n = 18, 9 in control and 9 in LSD). The left cardiac sympathetic nerve was denervated with irrigated catheter radiofrequency ablation...
June 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27378266/-the-crux-of-the-sacroiliac-joint
#17
J Fleisch, A Dahan
Pain from the sacroiliac (SI) joint is, along with osteoarthritis of the facet joints, one of the main sources of mechanical low back pain. Here we discuss the negative results of two recent randomized controlled trials in the Netherlands on the use of radiofrequency (RF) denervation to treat low back pain arising from the SI joint. Possible causes of treatment failure are discussed. The authors also discuss the use of an intra-articular injection of the combination of a local anaesthetic and a glucocorticoid as an alternative to RF denervation...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27319336/renal-denervation-in-the-era-of-htn-3-comprehensive-review-and-glimpse-into-the-future
#18
REVIEW
Joana Delgado Silva, Marco Costa, Bernard J Gersh, Lino Gonçalves
The pathophysiological role of sympathetic overactivity in conditions such as hypertension has been well documented. Catheter-based renal denervation (RDN) is a minimally invasive percutaneous procedure which aims to disrupt sympathetic nerve afferent and efferent activity through the application of radiofrequency energy directly within the renal artery wall. This technique has emerged as a very promising treatment with dramatic effects on refractory hypertension but also in other conditions in which a sympathetic influence is present...
August 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27318998/left-sympathetic-cardiac-denervation-in-managing-electrical-storm-acute-outcome-and-long-term-follow-up
#19
Mukund A Prabhu, Srinivas B V Prasad, S P Abhilash, Anees Thajudeen, Balasubramoniam K R, Narayanan Namboodiri
PURPOSE: Left sympathetic cardiac denervation (LSCD) may be beneficial in treating electrical storm (ES) of varied aetiologies. The present study analyse the outcome and long term follow up of LSCD in treating ES. METHODS: This is a retrospective study of patients with ES who underwent LSCD. RESULTS: Nine patients (majority males (88.89 %), median age 52 years, IQR 50.5-56.5) underwent LSCD. Coronary artery disease was the commonest substrate (7 (77...
December 2016: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/27296507/radiofrequency-renal-denervation-protects-the-ischemic-heart-via-inhibition-of-grk2-and-increased-nitric-oxide-signaling
#20
David J Polhemus, Juan Gao, Amy L Scarborough, Rishi Trivedi, Kathleen H McDonough, Traci T Goodchild, Frank Smart, Daniel R Kapusta, David J Lefer
RATIONALE: Catheter-based renal denervation (RDN) is currently under development for the treatment of resistant hypertension and is thought to reduce blood pressure via interruption of sympathetic pathways that modulate cardiovascular function. The sympathetic nervous system also plays a critical role in the pathogenesis of acute myocardial infarction and heart failure. OBJECTIVE: We examined whether treatment with radiofrequency (RF)-RDN would protect the heart against subsequent myocardial ischemia/reperfusion injury via direct effects on the myocardium...
July 22, 2016: Circulation Research
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