Saverio Continisio, Carolina Montonati, Filippo Angelini, Pier Paolo Bocchino, Carla Carbonaro, Federico Giacobbe, Veronica Dusi, Ovidio De Filippo, Alfonso Ielasi, Giuseppe Giannino, Emiliano Boldi, Tommaso Fabris, Fabrizio D'Ascenzo, Gaetano Maria De Ferrari, Giuseppe Tarantini
BACKGROUND: In the last few years, percutaneous LAA occlusion (LAAO) has become a plausible alternative in atrial fibrillation (AF) patients with contraindications to anticoagulation therapy. Nevertheless, the optimal antiplatelet strategy following percutaneous LAAO remains to be defined. METHODS: Studies comparing single antiplatelet therapy (SAPT) versus dual antiplatelet therapy (DAPT) following LAAO were systematically searched and screened. The outcomes of interest were ischemic stroke, device-related thrombus (DRT) and major bleeding...
April 10, 2024: European Journal of Clinical Investigation