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https://www.readbyqxmd.com/read/28527321/short-term-exposure-to-gold-nanoparticle-suspension-impairs-swimming-behavior-in-a-widespread-calanoid-copepod
#1
François-Gaël Michalec, Markus Holzner, Alexandre Barras, Anne-Sophie Lacoste, Loïc Brunet, Jae-Seong Lee, Christian Slomianny, Rabah Boukherroub, Sami Souissi
Calanoid copepods play an important role in the functioning of marine and brackish ecosystems. Information is scarce on the behavioral toxicity of engineered nanoparticles to these abundant planktonic organisms. We assessed the effects of short-term exposure to nonfunctionalized gold nanoparticles on the swimming behavior of the widespread estuarine copepod Eurytemora affinis. By means of three-dimensional particle tracking velocimetry, we reconstructed the trajectories of males, ovigerous and non-ovigerous females...
May 17, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28525549/the-change-in-circulating-galectin-3-predicts-absence-of-atrial-fibrillation-after-thoracoscopic-surgical-ablation
#2
Wouter R Berger, Benoît Jagu, Nicoline W E van den Berg, Dean R P P Chan Pin Yin, Jan P van Straalen, Onno J de Boer, Antoine H G Driessen, Jolien Neefs, Sébastien P J Krul, WimJan P van Boven, Allard C van der Wal, Joris R de Groot
Aims: Galectin-3 (Gal-3) is an important mediator of cardiac fibrosis, particularly in heart failure. Increased Gal-3 concentration (Gal-3), associated with increased risk of developing atrial fibrillation (AF), may reflect atrial fibrotic remodelling underlying AF progression. We aimed to investigate whether the change in serum Gal-3 reflects alterations of the arrhythmogenic atrial substrate following thoracoscopic AF surgery, and predicts absence of AF. Methods and results: Consecutive patients undergoing thoracoscopic AF surgery were included...
May 19, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28522304/left-atrial-appendage-occlusion-with-the-lambre-device-initial-experience
#3
Ignacio Cruz-González, Xavier Freixa, José Antonio Fernández-Díaz, José Carlos Moreno-Samos, Victoria Martín-Yuste, Javier Goicolea
No abstract text is available yet for this article.
May 15, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28522235/a-review-of-terrestrial-aerial-and-aquatic-keratins-the-structure-and-mechanical-properties-of-pangolin-scales-feather-shafts-and-baleen-plates
#4
Bin Wang, Tarah N Sullivan
Keratinous materials, omnipresent as the hard and durable epidermal appendages of animals, are one of the toughest biological materials. They exhibit diverse morphologies and structures that serve a variety of amazing and inspiring mechanical functions. In this work, we provide a review of representative terrestrial, aerial and aquatic keratinous materials, pangolin scales, feather shafts and baleen plates, and correlate their hierarchical structures to respective functions of dermal armor, flight material and undersea filter...
May 8, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28515740/left-atrial-appendage-occlusion-procedures
#5
EDITORIAL
Krzysztof Bartuś
No abstract text is available yet for this article.
March 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28515329/inference-of-facultative-mobility-in-the-enigmatic-ediacaran-organism-parvancorina
#6
Simon A F Darroch, Imran A Rahman, Brandt Gibson, Rachel A Racicot, Marc Laflamme
Establishing how Ediacaran organisms moved and fed is critical to deciphering their ecological and evolutionary significance, but has long been confounded by their non-analogue body plans. Here, we use computational fluid dynamics to quantitatively analyse water flow around the Ediacaran taxon Parvancorina, thereby testing between competing models for feeding mode and mobility. The results show that flow was not distributed evenly across the organism, but was directed towards localized areas; this allows us to reject osmotrophy, and instead supports either suspension feeding or detritivory...
May 2017: Biology Letters
https://www.readbyqxmd.com/read/28514632/a-waterborne-pursuit-deterrent-signal-deployed-by-a-sea-urchin
#7
Hannah Sheppard-Brennand, Alistair G B Poore, Symon A Dworjanyn
Selection by consumers has led to the evolution of a vast array of defenses in animals and plants. These defenses include physical structures, behaviors, and chemical signals that mediate interactions with predators. Some of the strangest defensive structures in nature are the globiferous pedicellariae of the echinoderms. These are small venomous appendages with jaws and teeth that cover the test of many sea urchins and sea stars. In this study, we report a unique use of these defensive structures by the collector sea urchin Tripneustes gratilla...
June 2017: American Naturalist
https://www.readbyqxmd.com/read/28506939/printed-mdct-3d-models-for-prediction-of-left-atrial-appendage-laa-occluder-device-size-a-feasibility-study
#8
Orly Goitein, Noam Fink, Victor Guetta, Roy Beinart, Yafim Brodov, Eli Konen, David Goitein, Elio Di Segni, Avishay Grupper, Michael Glikson
AIMS: Trans-esophageal echocardiography (TEE) and MDCT currently serve as imaging modalities for left atrial appendage (LAA) occlusion pre-procedural planning. We assessed the feasibility of multi-detector CT (MDCT) based models to predict the correct size of device for LAA occlusion procedures. METHODS AND RESULTS: Patients planned for LAA occlusion underwent MDCT before implantation, which was used for creating and printing 3D LAA models. Three cardiologists evaluated the 3D models and predicted the correct size of the device by manual manipulation, these predictions were compared with the actual device implanted during the procedure...
May 16, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504238/united-kingdom-coronary-and-structural-heart-interventions-from-2010-to-2015
#9
Peter F Ludman, Mark A de Belder, Simon Redwood, Adrian Banning
In the United Kingdom, a clinical data set is completed for every patient undergoing coronary intervention and certain structural interventions, and sent to central servers in the National Institute for Cardiovascular Outcomes Research (NICOR) on behalf of the British Cardiovascular Intervention Society (BCIS). These data are linked to the national mortality register. In addition, data are obtained about the structure of healthcare provision using an annual survey. Analyses of these data are provided for different audiences in several formats...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504234/spain-coronary-and-structural-heart-interventions-from-2010-to-2015
#10
Bruno García Del Blanco, Pilar Jiménez Quevedo, José D Diaz, Felipe Hernández, José Ramón Rumoroso, Manel Sabaté, José Maria de la Torre Hernandez, Ana Serrador, Armando Pérez de Prado, Javier Goicolea, Ramiro Trillo, Manolo Pan
Since 1990 The Spanish Society of Cardiology Working Group on Cardiac Catheterization and Interventional Cardiology has presented a yearly report on the data collected in the National Registry, with online support since 2010. The Steering Committee has analysed all data provided voluntarily by institutions, which consisted of a total of anywhere between 105 and 113 hospitals. Medical care was provided to a population of 46.8 million inhabitants in 2015. During this period, diagnostic procedures increased progressively from 2010, reaching a maximum of 145,836 in 2015, 86% (125,484) corresponding to coronary angiograms...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504231/poland-coronary-and-structural-heart-interventions-from-2010-to-2015
#11
Jacek Legutko, Zbigniew Siudak, Radosław Parma, Andrzej Ochała, Dariusz Dudek
For the last five years, invasive cardiology in Poland has developed extensively. Currently, 98% of the 161 Polish cathlabs operate in 24/7 mode, 37 of them supported by cardiac surgery departments on-site. A certification curriculum for interventional cardiology operators is supported by dedicated workshops and scientific meetings during national conferences. The rise in the number of coronary angiographies and PCIs was paralleled by an increased use of drug-eluting stents, bioresorbable vascular scaffolds and physiologic assessment of coronary arteries...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28504228/italy-coronary-and-structural-heart-interventions-from-2010-to-2015
#12
Sergio Berti, Ferdinando Varbella, Alfredo Marchese, Luigi Emilio Pastormerlo, Giuseppe Musumeci
The aim of this report is to analyse trends in Italian cathlab activity between 2010 and 2015. Data were obtained from the national database of the Italian Society of Interventional Cardiology (GISE), which includes 97% of Italian cardiac catheterisation laboratories. The number of percutaneous coronary interventions (PCI) has remained relatively stable in the past five years. We have observed a significant increase in the number of primary PCI (pPCI) from 471.5 to 557.5 per million inhabitants with a consequent reduction of rescue primary PCI/fibrinolysis...
May 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28500479/-catheter-ablation-of-persistent-atrial-fibrillation-where-do-we-go
#13
C Lemeš, K-H Kuck, S Mathew
Despite the very promising initial results of clinical studies, catheter ablation of persistent atrial fibrillation (AF) remains a challenge in modern electrophysiology. On the basis of the hypothesized pathophysiological mechanisms, a variety of ablation strategies have been developed over the course of time. The current ablation strategies range from pulmonary vein isolation (PVI) alone as first-line therapy, through ablation of multiple linear lesions, ablation of complex fractionated atrial electrograms (CFAE), rotor ablation, isolation of fibrotic and scar tissue up to isolation of the left atrial appendage (LAA); however, it is unclear even to the present day whether these complex and time-consuming strategies actually improve the success rate of ablation therapy...
May 12, 2017: Herz
https://www.readbyqxmd.com/read/28496929/management-of-patients-with-atrial-fibrillation-focus-on-treatment-options
#14
REVIEW
Pawel Matusik, Jacek Lelakowski, Barbara Malecka, Jacek Bednarek, Remigiusz Noworolski
Atrial fibrillation (AF) is leading cardiac arrhythmia with important clinical implications. Its diagnosis is usually made on the basis on 12-lead ECG or 24-hour Holter monitoring. More and more clinical evidence supports diagnostic use of cardiac event recorders and cardiovascular implantable electronic devices (CIED). Treatment options in patients with atrial fibrillation are extensive and are based on chosen rhythm and/or rate control strategy. The use and selected contraindications to AF related pharmacotherapy, including anticoagulants are shown...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28496927/e-ea-for-the-prediction-of-left-atrial-appendage-thrombi-in-patients-with-atrial-fibrillation-and-severe-mitral-stenosis
#15
Atoosheh Rohani, Hoorak Poorzand, Mohammad R Arefifar
Atrial fibrillation (AF), left atrial appendage thrombi (LAAT) and subsequent embolic stroke are the most frequent complications of mitral stenosis .E/Ea is used traditionally for the assessment of left atrium pressure, and besides AF and dilated LA size which promotes stasis of blood in LA, high LA pressure also play a role to clot formation in LA .The receiver operator characteristics (ROC) curve point-coordinates identified an E:e' value of ≥ 36.5to have 57.14% sensitivity and 90.91% specificity for LAAT;We find this ratio relatively specific for prediction of LAAT, independent of MVA and LA volume, however it needs to be externally validated...
October 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/28495432/changes-in-coagulation-and-platelet-activation-markers-following-transcatheter-left-atrial-appendage-closure
#16
Josep Rodés-Cabau, Gilles O'Hara, Jean-Michel Paradis, Mathieu Bernier, Tania Rodriguez-Gabella, Ander Regueiro, Kim O'Connor, Jonathan Beaudoin, Rishi Puri, Mélanie Côté, Jean Champagne
The recommendations for antithrombotic treatment after left atrial appendage closure (LAAC) remain empirical, and no data exist on the changes in hemostatic markers associated with LACC. The objective of the present study is to determine the presence, degree, and timing of changes in the markers of platelet and coagulation activation after LAAC. Forty-three patients (mean age 76 ± 9 years, 23 men) with atrial fibrillation who underwent successful LACC with the Watchman (n = 27) or Amplatzer Cardiac Plug (n = 16) devices were included in the study...
April 12, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28495117/first-experience-with-the-watchman-flx-occluder-for-percutaneous-left-atrial-appendage-closure
#17
Julia Seeger, Ralf Birkemeyer, Wolfgang Rottbauer, Jochen Wöhrle
BACKGROUND: We aimed to evaluate efficacy and safety of left atrial appendage (LAA) closure with the new Watchman FLX and analyze procedural features in a consecutive series of high risk non-valvular atrial fibrillation patients. METHODS AND RESULTS: Twelve consecutive non-valvular atrial fibrillation patients (age 76.6±7.8years) at high risk for stroke (CHA2DS2-VASc-Score 5.5±0.9) and bleeding (HAS-BLED-Score 3.8±0.9), received LAA closure with the Watchman FLX...
April 29, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28493331/pilus-biogenesis-of-gram-positive-bacteria-roles-of-sortases-and-implications-for-assembly
#18
REVIEW
Baldeep Khare, Sthanam Vl Narayana
Successful adherence, colonization, and survival of Gram-positive bacteria require surface proteins, and multi-protein assemblies called pili. These surface appendages are attractive pharmacotherapeutic targets and understanding their assembly mechanisms is essential for identifying a new class of 'anti-infectives' that do not elicit microbial resistance. Molecular details of the Gram-negative pilus assembly are available in-depth, but the Gram-positive pilus biogenesis is still an emerging field and investigations continue to reveal novel insights into this process...
May 10, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28491759/termination-of-anticoagulation-therapy-at-45-days-after-concomitant-atrial-fibrillation-catheter-ablation-and-left-atrial-appendage-occlusion-resulting-in-device-related-thrombosis-and-stroke
#19
https://www.readbyqxmd.com/read/28491735/air-emboli-during-the-procedure-of-transcatheter-left-atrial-appendage-closure
#20
Shuang Li, Wei Chen, Shuang Li, Dongdong Zhao, Kai Tang, Yat-Yam Lam, Yawei Xu
No abstract text is available yet for this article.
November 2016: HeartRhythm Case Reports
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