keyword
https://read.qxmd.com/read/38634701/pharmacokinetics-of-tranexamic-acid-txa-delivered-by-expeditious-routes-in-a-swine-model-of-polytrauma-and-hemorrhagic-shock
#1
JOURNAL ARTICLE
Mallori Wilson, Sean Stuart, Brittany Lassiter, Timothy Parker, Clyde Martin, Robert Healy, Christopher Treager, Eric Sulava, Lorie Gower, Pravina Fernandez, Emily Friedrich
OBJECTIVE: Hemorrhage is the leading cause of preventable death in civilian trauma centers and on the battlefield. One of the emerging treatment options for hemorrhage in austere environments is tranexamic acid (TXA). However, the landscape is not amenable to the current delivery standard. This study compared the pharmacokinetics of TXA via a standard 10-minute intravenous infusion (IV infusion), intravenous rapid push over 10 s (IV push), and intramuscular injection (IM) in a swine polytrauma and hemorrhagic shock model (trauma group) compared to uninjured controls (control group)...
April 18, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38634125/epidemiology-and-severity-of-medical-events-for-mountain-bikers-and-hikers-transported-by-ambulance-in-western-australia-2015-to-2020
#2
JOURNAL ARTICLE
Paul J Braybrook, Hideo Tohira, Deon Brink, Judith Finn, Peter L Buzzacott
INTRODUCTION: Outdoor activities offer physical and mental health benefits. However, incidents can occur requiring ambulance transport to hospital. This study aimed to describe the epidemiology and severity of traumatic and medical incidents for mountain bikers and hikers transported by ambulance within Western Australia. METHODS: This was a retrospective cohort study of ambulance-transported mountain bikers and hikers within Western Australia from 2015 to 2020...
April 18, 2024: Wilderness & Environmental Medicine
https://read.qxmd.com/read/38634073/thoracic-ultrasound-may-improve-paramedic-diagnostic-and-management-accuracy-in-undifferentiated-respiratory-distress
#3
JOURNAL ARTICLE
Emily Fitzgerald, Shelby Parker, Sarah Hancock, Courtney Marie-Cora Jones, Julie Kittel, John DeAngelis, Maia Dorsett
OBJECTIVES: Patients with chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) exacerbations present with similar history and physical examination findings. This complicates both the diagnostic process and the creation of appropriate treatment plans for patients presenting in respiratory distress, particularly in the prehospital setting. Thoracic point-of-care-ultrasound (POCUS) may increase diagnostic accuracy; however, its potential to improve patient management by emergency medical services clinicians is unknown...
April 2024: Journal of the American College of Emergency Physicians open
https://read.qxmd.com/read/38631798/out-of-hospital-cardiac-arrest
#4
REVIEW
Ryan B Gerecht, Jose V Nable
Survival from out-of-hospital cardiac arrest (OHCA) is predicated on a community and system-wide approach that includes rapid recognition of cardiac arrest, capable bystander CPR, effective basic and advanced life support (BLS and ALS) by EMS providers, and coordinated postresuscitation care. Management of these critically ill patients continues to evolve. This article focuses on the management of OHCA by EMS providers.
May 2024: Cardiology Clinics
https://read.qxmd.com/read/38627852/optimizing-remote-and-rural-prehospital-resources-using-air-transport-of-thrombectomy-candidates
#5
REVIEW
Pauli Vuorinen, Piritta Setälä, Sanna Hoppu
BACKGROUND: In Finland, the yearly number of mechanical thrombectomies for acute stroke is increasing and more patients are transported over 100 km to the comprehensive stroke centre (CSC) for definitive care. This leaves the rural townships without immediate emergency medical services (EMS) for hours. In this study we compare the EMS' estimated return times to own station after the handover of a thrombectomy candidate between two transport methods: (1) using ground transportation with an ambulance to the CSC or (2) using a hydrid strategy starting the transportation with an ambulance and continuing by air with a helicopter emergency medical services unit (HEMS)...
April 16, 2024: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://read.qxmd.com/read/38627823/effect-of-intra-arrest-transport-extracorporeal-cardiopulmonary-resuscitation-and-immediate-invasive-assessment-in-refractory-out-of-hospital-cardiac-arrest-a-long-term-follow-up-of-the-prague-ohca-trial
#6
RANDOMIZED CONTROLLED TRIAL
Daniel Rob, Klaudia Farkasovska, Marketa Kreckova, Ondrej Smid, Petra Kavalkova, Jaromir Macoun, Michal Huptych, Petra Havrankova, Juraj Gallo, Jan Pudil, Milan Dusik, Stepan Havranek, Ales Linhart, Jan Belohlavek
BACKGROUND: Randomized data evaluating the impact of the extracorporeal cardiopulmonary resuscitation (ECPR) approach on long-term clinical outcomes in patients with refractory out-of-hospital cardiac arrest (OHCA) are lacking. The objective of this follow-up study was to assess the long-term clinical outcomes of the ECPR-based versus CCPR approach. METHODS: The Prague OHCA trial was a single-center, randomized, open-label trial. Patients with witnessed refractory OHCA of presumed cardiac origin, without return of spontaneous circulation, were randomized during ongoing resuscitation on scene to conventional CPR (CCPR) or an ECPR-based approach (intra-arrest transport, ECPR if ROSC is not achieved prehospital and immediate invasive assessment)...
April 16, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38626643/fixed-dose-ketamine-for-prehospital-management-of-hyperactive-delirium-with-severe-agitation
#7
JOURNAL ARTICLE
Michael C O'Brien, Kyle J Kelleran, Susan J Burnett, Kaylee A Hausrath, Mary S Kneer, Nan Nan, Chang-Xing Ma, Robert W McCartin, Brian M Clemency
INTRODUCTION: Patients exhibiting signs of hyperactive delirium with severe agitation (HDSA) may require sedating medications for stabilization and safe transport to the hospital. Determining the patient's weight and calculating the correct weight-based dose may be challenging in an emergency. A fixed dose ketamine protocol is an alternative to the traditional weight-based administration, which may also reduce dosing errors. The objective of this study was to evaluate the frequency and characteristics of adverse events following pre-hospital ketamine administration for HDSA...
April 9, 2024: American Journal of Emergency Medicine
https://read.qxmd.com/read/38626286/dispatch-categories-as-indicators-of-out-of-hospital-time-critical-interventions-and-associated-emergency-department-outcomes
#8
JOURNAL ARTICLE
Matthew J Levy, Remle P Crowe, Heidi Abraham, Anna Bailey, Matt Blue, Reinhard Ekl, Eric Garfinkel, Joshua B Holloman, Jeff Hutchens, Ryan Jacobsen, Colin Johnson, Asa Margolis, Ruben Troncoso, Jefferson G Williams, J Brent Myers
OBJECTIVES: Emergency medical services (EMS) systems increasingly grapple with rising call volumes and workforce shortages, forcing systems to decide which responses may be delayed. Limited research has linked dispatch codes, on-scene findings, and emergency department (ED) outcomes. This study evaluated the association between dispatch categorizations and time-critical EMS responses defined by prehospital interventions and ED outcomes. Secondarily, we proposed a framework for identifying dispatch categorizations that are safe or unsafe to hold in queue...
April 16, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38626165/in-response-to-dr-golcuk-re-delta-shock-index-enhancing-prehospital-assessment-of-gi-bleeding
#9
JOURNAL ARTICLE
Joshua Lowe
No abstract text is available yet for this article.
April 16, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38625453/the-chain-of-survival-and-rehabilitation-for-sepsis-concepts-and-proposals-for-healthcare-trajectory-optimization
#10
REVIEW
Romain Jouffroy, Félix Djossou, Rémi Neviere, Samir Jaber, Benoît Vivien, Nicholas Heming, Papa Gueye
This article describes the structures and processes involved in healthcare delivery for sepsis, from the prehospital setting until rehabilitation. Quality improvement initiatives in sepsis may reduce both morbidity and mortality. Positive outcomes are more likely when the following steps are optimized: early recognition, severity assessment, prehospital emergency medical system activation when available, early therapy (antimicrobials and hemodynamic optimization), early orientation to an adequate facility (emergency room, operating theater or intensive care unit), in-hospital organ failure resuscitation associated with source control, and finally a comprehensive rehabilitation program...
April 16, 2024: Annals of Intensive Care
https://read.qxmd.com/read/38622511/from-symptom-onset-to-ed-departure-understanding-the-acute-care-chain-for-patients-with-undifferentiated-complaints-a-prospective-observational-study
#11
JOURNAL ARTICLE
Lieke Claassen, Laura Magdalena Ritter, Gideon Hubertus Petrus Latten, Noortje Zelis, Jochen Willo Lennert Cals, Patricia Maria Stassen
BACKGROUND: For most acute conditions, the phase prior to emergency department (ED) arrival is largely unexplored. However, this prehospital phase has proven an important part of the acute care chain (ACC) for specific time-sensitive conditions, such as stroke and myocardial infarction. For patients with undifferentiated complaints, exploration of the prehospital phase of the ACC may also offer a window of opportunity for improvement of care. This study aims to explore the ACC of ED patients with undifferentiated complaints, with specific emphasis on time in ACC and patient experience...
April 15, 2024: International Journal of Emergency Medicine
https://read.qxmd.com/read/38619868/safety-and-adverse-events-during-primary-care-paramedic-interfacility-transfer-of-stable-stemi-patients
#12
JOURNAL ARTICLE
Michael Feldman, Fahad Bahaidarah, Mahbod Rahimi, Sara Howaidi, Linda Turner, P Richard Verbeek, Warren Cantor, Sheldon Cheskes, Ian Drennan, Kristen Gilmartin
OBJECTIVE: Current guidelines recommend that patients presenting with ST-elevation myocardial infarction (STEMI) to hospitals not capable of performing primary percutaneous coronary intervention (PCI) be transferred to a PCI-capable hospital if reperfusion can be accomplished within 120 minutes. Most STEMI patients are accompanied by an advanced care paramedic (ACP, equivalent to EMT-P), nurse, or physician who can manage complications should they arise. In our region, stable STEMI patients are transported by primary care paramedics (PCPs, similar scope of practice to advanced EMT) in cases where a nurse, physician, or ACP paramedic is not available...
April 15, 2024: Prehospital Emergency Care
https://read.qxmd.com/read/38618841/effect-of-the-presence-of-emergency-departments-with-300-or-more-hospital-beds-in-health-service-areas-on-30-day-mortality-in-korea-a-nationwide-retrospective-cross-sectional-study
#13
JOURNAL ARTICLE
Stephen Gyung Won Lee, Haibin Bai, Joo Won Park, Seonhwa Lee, Mi Young Kwak, Won Mo Jang, Yoon Kim
BACKGROUND: Disparities in emergency care accessibility exist between health service areas (HSAs). There is limited evidence on whether the presence of an emergency department (ED) that exceeds a certain hospital bed capacity is associated with emergency patient outcomes at the regional level. The objective of this study was to evaluate the effect of HSAs with or without of regional or local emergency centers with 300 or more hospital beds (EC300 or nEC300, respectively) by comparing the 30-day mortality of patients with severe emergency diseases (SEDs) admitted to the hospital through the ED...
March 17, 2024: International Journal of Health Policy and Management
https://read.qxmd.com/read/38614365/current-status-of-emergency-medical-service-use-in-st-segment-elevation-myocardial-infarction-in-china-findings-from-china-acute-myocardial-infarction-cami-registry
#14
JOURNAL ARTICLE
Jingang Yang, Yanyan Zhao, Jianyi Wang, Liyuan Ma, Haiyan Xu, Wenxiu Leng, Yang Wang, Yan Wang, Zhifang Wang, Xiaojin Gao, Yuejin Yang
BACKGROUND: The mortality rate of myocardial infarction in China has increased dramatically in the past three decades. Although emergency medical service (EMS) played a pivotal role for the management of patients with ST-segment elevation myocardial infarction (STEMI), the corresponding data in China are limited. METHODS: An observational analysis was performed in 26,305 STEMI patients, who were documented in China acute myocardial infarction (CAMI) Registry and treated in 162 hospitals from January 1st, 2013 to January 31th, 2016...
April 11, 2024: International Journal of Cardiology
https://read.qxmd.com/read/38613681/interobserver-variability-in-preclinical-assessment-of-collision-variables-following-traffic-accidents
#15
JOURNAL ARTICLE
Michael Hetz, Julius Rosch, Thomas Unger, Manuel F Struck, Klaus-Dieter Schaser, Christian Kleber
PURPOSE: Traffic accidents persist as a leading cause of death. European law mandates the integration of automatic emergency call systems (eCall). Our project focuses on an automated injury prediction device for car accidents, correlating technical and epidemiological input data, such as age, gender, seating position, impact on the passenger compartment, seatbelt usage, impact direction, EES, vehicle class, and airbag deployment. This study aims to explore interobserver variability in data collection quality in real accident scenarios...
April 13, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38613475/clinical-implications-of-over-and-under-triage-using-need-for-trauma-intervention-and-cribari-indices
#16
JOURNAL ARTICLE
Emily K Lenart, Saskya E Byerly, Megan G Gross, Yasmin M Ali, Cory R Evans, Thomas S Easterday, Isaac W Howley, Andy J Kerwin, Peter E Fischer, Dina M Filiberto
BACKGROUND: Need for Trauma Intervention (NFTI) score was proposed to help identify injured trauma patients while minimizing under (UT) and over triage (OT). Using a national database, we aimed to describe UT and OT of NFTI vs standard Cribari method (CM) and hypothesized triage sensitivity remains poor. METHODS: The 2021 Trauma Quality Improvement Program (TQIP) database was queried. Demographics, mechanism, verification level, interfacility transfer (IF), and level of activation were collected...
April 13, 2024: American Surgeon
https://read.qxmd.com/read/38610746/blood-pressure-variability-in-acute-stroke-a-narrative-review
#17
REVIEW
Christina Zompola, Lina Palaiodimou, Konstantinos Voumvourakis, Leonidas Stefanis, Aristeidis H Katsanos, Else C Sandset, Estathios Boviatsis, Georgios Tsivgoulis
The management of blood pressure variability (BPV) in acute stroke presents a complex challenge with profound implications for patient outcomes. This narrative review examines the role of BPV across various stages of acute stroke care, highlighting its impact on treatment strategies and prognostic considerations. In the prehospital setting, while guidelines lack specific recommendations for BP management, emerging evidence suggests a potential link between BPV and outcomes. Among ischaemic stroke patients who are ineligible for reperfusion therapies, BPV independently influences functional outcomes, emphasising the need for individualised approaches to BP control...
March 29, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610595/predictors-of-short-term-trauma-laparotomy-outcomes-in-an-integrated-military-civilian-health-system-a-23-year-retrospective-cohort-study
#18
JOURNAL ARTICLE
Sami Gendler, Shaul Gelikas, Tomer Talmy, Roy Nadler, Avishai M Tsur, Irina Radomislensky, Moran Bodas, Elon Glassberg, Ofer Almog, Avi Benov, Jacob Chen
Background : Trauma laparotomy (TL) remains a cornerstone of trauma care. We aimed to investigate prehospital measures associated with in-hospital mortality among casualties subsequently undergoing TLs in civilian hospitals. Methods : This retrospective cohort study cross-referenced the prehospital and hospitalization data of casualties treated by Israel Defense Forces-Medical Corps teams who later underwent TLs in civilian hospitals between 1997 and 2020. Results : Overall, we identified 217 casualties treated by IDF-MC teams that subsequently underwent a TL, with a mortality rate of 15...
March 22, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38609897/changes-in-temperature-in-preheated-crystalloids-at-ambient-temperatures-relevant-to-a-prehospital-setting-an-experimental-simulation-study-with-the-application-of-prehospital-treatment-of-trauma-patients-suffering-from-accidental-hypothermia
#19
JOURNAL ARTICLE
Emil Jensen, Helena Rentzhog, Johan Herlitz, Christer Axelsson, Peter Lundgren
BACKGROUND: Accidental hypothermia is common in all trauma patients and contributes to the lethal diamond, increasing both morbidity and mortality. In hypotensive shock, fluid resuscitation is recommended using fluids with a temperature of 37-42°, as fluid temperature can decrease the patient's body temperature. In Sweden, virtually all prehospital services use preheated fluids. The aim of the present study was to investigate how the temperature of preheated infusion fluids is affected by the ambient temperatures and flow rates relevant for prehospital emergency care...
April 12, 2024: BMC Emergency Medicine
https://read.qxmd.com/read/38609787/education-and-training-of-prehospital-first-responders-in-low-and-middle-income-countries
#20
JOURNAL ARTICLE
Zachary J Eisner, Ken Diango, Jared H Sun
Prehospital emergency medical services play a vital role in providing essential emergency medical and trauma care. However, in many low- and middle-income countries, there is a significant lack of adequate emergency medical services coverage, a problem compounded by a profound deficit of first responder training programs. The African Federation of Emergency Medicine classifies prehospital emergency care into 2 categories: tier-1, which includes laypersons, and tier-2, consisting of professionals equipped with dispatch capabilities...
April 11, 2024: Surgery
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